Homologous unequal cross-over within the human CYP2A gene cluster as a mechanism for the deletion of the entire CYP2A6 gene associated with the poor metabolizer phenotype

Journal of Biochemistry

Volumn 126, Issue 2, 1999, Pages 402-407

  Nunoya, Ken Ichi ^a   Yokoi, Tsuyoshi ^a   Takahashi, Yuki ^a   Kimura, Kanzo ^b   Kinoshita, Moritoshi ^c   Kamataki, Tetsuya ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^c OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Coumarin; Gene analysis; Genetic polymorphism; Pharmacogenetics; RFLP

Indexed keywords

CYTOCHROME P450 ISOENZYME; DNA;

ARTICLE; CROSSING OVER; DNA FLANKING REGION; DNA SEQUENCE; ENZYME POLYMORPHISM; GENE CLUSTER; GENE DELETION; HUMAN; HUMAN CELL; METABOLISM; PHARMACOGENETICS; POLYMERASE CHAIN REACTION;

EID: 0032838745     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022464     Document Type: Article

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