Quinoline and benzimidazole derivatives: Candidate probes for in vivo imaging of tau pathology in Alzheimer's disease

Journal of Neuroscience

Volumn 25, Issue 47, 2005, Pages 10857-10862

  Okamura, Nobuyuki ^a,b   Suemoto, Takahiro ^a   Furumoto, Shozo ^c   Suzuki, Masako ^a   Shimadzu, Hiroshi ^a   Akatsu, Hiroyasu ^d   Yamamoto, Takayuki ^d   Fujiwara, Hironori ^b   Nemoto, Miyako ^b   Maruyama, Masahiro ^b   Arai, Hiroyuki ^b   Yanai, Kazuhiko ^b   Sawada, Tohru ^a   Kudo, Yukitsuka ^a,c  

^a BF Research Institute Inc   (Japan)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

^d NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

A peptide; Imaging; Neurofibrillary tangles; Neuropathology; Paired helical filaments; Tau

Indexed keywords

2 (4 AMINOPHENYL)QUINOLINE; 2 [(4 METHYLAMINO)PHENYL]QUINOLINE; 4 [2 (2 BENZOIMIDAZOLYL)ETHENYL] N,N DIETHYLBENZENAMINE; BENZIMIDAZOLE DERIVATIVE; BF 126; BF 158; BF 170; QUINOLINE DERIVATIVE; TAU PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DISEASE SEVERITY; DRUG CLEARANCE; HISTOPATHOLOGY; MOLECULAR PROBE; MOUSE; NEUROFIBRILLARY TANGLE; NEUROPIL; NONHUMAN; PAIRED HELICAL FILAMENT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SENILE PLAQUE; TISSUE SECTION;

AGED; ALZHEIMER DISEASE; AMYLOID; ANILINE COMPOUNDS; ANIMALS; AUTORADIOGRAPHY; BENZIMIDAZOLES; BINDING, COMPETITIVE; BRAIN; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MICE; MICE, INBRED ICR; NEUROFIBRILLARY TANGLES; POSITRON-EMISSION TOMOGRAPHY; QUINOLINES; TAU PROTEINS;

EID: 28044460038     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1738-05.2005     Document Type: Article

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