메뉴 건너뛰기




Volumn 3, Issue 4, 2005, Pages 329-337

Activation of the RNA-dependent protein kinase (PKR) of lymphocytes by regulatory RNAs: Implications for immunomodulation in HIV infection

Author keywords

Cytokines; Interferon (IFN ); Noncoding RNAs; Nuclear factor kappa B (NF B); Regulatory RNA; RNA dependent protein kinase (PKR)

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOMODULATING AGENT; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; RNA; SYNTHETIC PEPTIDE;

EID: 27844589460     PISSN: 1570162X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016205774370447     Document Type: Review
Times cited : (13)

References (132)
  • 3
    • 4644309196 scopus 로고    scopus 로고
    • Nature. The functions of animal microRNAs
    • Ambros V. (2004). Nature. The functions of animal microRNAs. 431: 350-355.
    • (2004) , vol.431 , pp. 350-355
    • Ambros, V.1
  • 4
    • 0005665482 scopus 로고    scopus 로고
    • Cytotoxic T-Lymphocyte Response to HIV
    • Gupta S. Ed. New York, Plenum Press
    • Autran B. (1996). Cytotoxic T-Lymphocyte Response to HIV. In: Gupta S. Ed. Immunology of HIV Infection. New York, Plenum Press. pp. 201-228.
    • (1996) Immunology of HIV Infection , pp. 201-228
    • Autran, B.1
  • 5
    • 11444253965 scopus 로고    scopus 로고
    • HIV-1 TAR RNA: The target of molecular interactions between the virus and its host
    • Bannwarth S, Gatignol A. (2005). HIV-1 TAR RNA: the target of molecular interactions between the virus and its host. Current HIV Research. 3: 61-71.
    • (2005) Current HIV Research. , vol.3 , pp. 61-71
    • Bannwarth, S.1    Gatignol, A.2
  • 6
    • 0029061555 scopus 로고
    • Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation
    • Barber GN, Wambach M, Thompson S, Jagus R, Katze MG. (1995). Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation. Molecular and Cellular Biology. 15: 3138-3146.
    • (1995) Molecular and Cellular Biology , vol.15 , pp. 3138-3146
    • Barber, G.N.1    Wambach, M.2    Thompson, S.3    Jagus, R.4    Katze, M.G.5
  • 7
    • 4344569076 scopus 로고    scopus 로고
    • The role of CD8+ T-cell response in HIV infection
    • Benito JM, Lopez M, Soriano V. (2004). The role of CD8+ T-cell response in HIV infection. AIDS Reviews. 6: 79-88.
    • (2004) AIDS Reviews , vol.6 , pp. 79-88
    • Benito, J.M.1    Lopez, M.2    Soriano, V.3
  • 8
    • 0022635533 scopus 로고
    • Poly (A)-containing RNA from the spleens of mice with Chagas' disease triggers in vitro macrophage resistance to Trypanosoma cruzi
    • Bertolini MC, De Lucca FL. (1986). Poly (A)-containing RNA from the spleens of mice with Chagas' disease triggers in vitro macrophage resistance to Trypanosoma cruzi. Journal of Protozoology. 33: 81-84.
    • (1986) Journal of Protozoology , vol.33 , pp. 81-84
    • Bertolini, M.C.1    De Lucca, F.L.2
  • 9
    • 0029782652 scopus 로고    scopus 로고
    • Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR
    • Bevilacqua PC, Cech TR. (1996). Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR. Biochemistry. 35: 9983-9994.
    • (1996) Biochemistry , vol.35 , pp. 9983-9994
    • Bevilacqua, P.C.1    Cech, T.R.2
  • 10
    • 0032485912 scopus 로고    scopus 로고
    • Binding of the protein kinase PKR to RNAs with secondary structure defects: Role of the tandem A-G mismatch and noncontiguous helixes
    • Bevilacqua PC, George CX, Samuel CE, Cech TR. (1998). Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes. Biochemistry. 37: 6303-6316.
    • (1998) Biochemistry , vol.37 , pp. 6303-6316
    • Bevilacqua, P.C.1    George, C.X.2    Samuel, C.E.3    Cech, T.R.4
  • 11
    • 0014988196 scopus 로고
    • Uptake of nonviral nucleic acids by mammalian cells
    • Davidson JN, Cohn, WE Eds, New York, Academic Press
    • Bhargava PM, Shanmugam G. (1971). Uptake of nonviral nucleic acids by mammalian cells. In: Davidson JN, Cohn, WE Eds, Progress in Nucleic Acid Research and Molecular Biology. New York, Academic Press. pp. 103-192.
    • (1971) Progress in Nucleic Acid Research and Molecular Biology , pp. 103-192
    • Bhargava, P.M.1    Shanmugam, G.2
  • 13
    • 0036235730 scopus 로고    scopus 로고
    • The mRNA of the translationally controlled tumor protein P23/TCTP is a highly structured RNA, which activates the dsRNA-dependent protein kinase PKR
    • Bommer UA, Borovjagin AV, Greagg MA, Jeffrey IW, Russell P, Laing KG, Lee M, Clemens MJ. (2002). The mRNA of the translationally controlled tumor protein P23/TCTP is a highly structured RNA, which activates the dsRNA-dependent protein kinase PKR. RNA. 8: 478-496.
    • (2002) RNA , vol.8 , pp. 478-496
    • Bommer, U.A.1    Borovjagin, A.V.2    Greagg, M.A.3    Jeffrey, I.W.4    Russell, P.5    Laing, K.G.6    Lee, M.7    Clemens, M.J.8
  • 14
    • 0030928832 scopus 로고    scopus 로고
    • The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR
    • Brand SR, Kobayashi R, Mathews MB. (1997). The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR. The Journal of Biological Chemistry. 13: 8388-8395.
    • (1997) The Journal of Biological Chemistry , vol.13 , pp. 8388-8395
    • Brand, S.R.1    Kobayashi, R.2    Mathews, M.B.3
  • 17
    • 4544301217 scopus 로고    scopus 로고
    • Recent advances in the development of HIV-1 Tat-based vaccines
    • Caputo A, Gavioli R, Ensoli B. (2004). Recent advances in the development of HIV-1 Tat-based vaccines. Current HIV Research. 2: 357-376.
    • (2004) Current HIV Research , vol.2 , pp. 357-376
    • Caputo, A.1    Gavioli, R.2    Ensoli, B.3
  • 19
    • 0030725442 scopus 로고    scopus 로고
    • The double-stranded RNA-dependent protein kinase PKR: Structure and function
    • Clemens MJ, Elia A. (1997). The double-stranded RNA-dependent protein kinase PKR: structure and function. Journal of Interferon Cytokine Research. 17: 503-524.
    • (1997) Journal of Interferon Cytokine Research , vol.17 , pp. 503-524
    • Clemens, M.J.1    Elia, A.2
  • 22
    • 2342641580 scopus 로고    scopus 로고
    • Targets and mechanisms for the regulation of translation in malignant transformation
    • Clemens MJ. (2004). Targets and mechanisms for the regulation of translation in malignant transformation. Oncogene. 23: 3180-3188.
    • (2004) Oncogene , vol.23 , pp. 3180-3188
    • Clemens, M.J.1
  • 23
    • 0043199284 scopus 로고    scopus 로고
    • How HIV Evades CTL Recognition
    • Collins KL. (2003). How HIV Evades CTL Recognition. Current HIV Research. 1: 31-40.
    • (2003) Current HIV Research , vol.1 , pp. 31-40
    • Collins, K.L.1
  • 24
    • 0033614407 scopus 로고    scopus 로고
    • The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro
    • Cuddihy AR, Wong AH, Tam NW, Li S, Koromilas AE. (1999). The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro. Oncogene. 18: 2690-2702.
    • (1999) Oncogene , vol.18 , pp. 2690-2702
    • Cuddihy, A.R.1    Wong, A.H.2    Tam, N.W.3    Li, S.4    Koromilas, A.E.5
  • 25
    • 0030033398 scopus 로고    scopus 로고
    • In vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3′ untranslated regions of human alpha-tropomyosin
    • Davis S, Watson JC. (1996). In vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3′ untranslated regions of human alpha-tropomyosin. Proceedings of the National Academy of Sciences USA. 93: 508-513.
    • (1996) Proceedings of the National Academy of Sciences USA , vol.93 , pp. 508-513
    • Davis, S.1    Watson, J.C.2
  • 27
    • 0020072375 scopus 로고
    • In vitro transfer of reactivity to Trypanosoma cruzi antigens from rat cells to human cells with immune RNA
    • De Lucca FL, Bertolini MC, Zini MN. (1982). In vitro transfer of reactivity to Trypanosoma cruzi antigens from rat cells to human cells with immune RNA. Journal of Infectious Diseases. 45: 148-151.
    • (1982) Journal of Infectious Diseases , vol.45 , pp. 148-151
    • De Lucca, F.L.1    Bertolini, M.C.2    Zini, M.N.3
  • 28
    • 0035708686 scopus 로고    scopus 로고
    • Effect of the calcium phosphate-mediated RNA uptake on the transfer of cellular immunity of a synthetic peptide of HIV-1 to human lymphocytes by exogenous RNA
    • De Lucca FL, Sawan FM, Watanabe MAE, Souza LR. (2001). Effect of the calcium phosphate-mediated RNA uptake on the transfer of cellular immunity of a synthetic peptide of HIV-1 to human lymphocytes by exogenous RNA. Molecular and Cellular Biochemistry. 228: 9-14.
    • (2001) Molecular and Cellular Biochemistry , vol.228 , pp. 9-14
    • De Lucca, F.L.1    Sawan, F.M.2    Watanabe, M.A.E.3    Souza, L.R.4
  • 29
    • 0036718372 scopus 로고    scopus 로고
    • Evidence for the involvement of the RNA-dependent protein kinase (PKR) in the induction of human cytotoxic T lymphocytes against a synthetic peptide of HIV-1 by regulatory RNA
    • De Lucca FL, Sales VSF, Sousa LR, Watanabe MAE. (2002). Evidence for the involvement of the RNA-dependent protein kinase (PKR) in the induction of human cytotoxic T lymphocytes against a synthetic peptide of HIV-1 by regulatory RNA. Molecular and Cellular Biochemistry. 238: 19-26.
    • (2002) Molecular and Cellular Biochemistry , vol.238 , pp. 19-26
    • De Lucca, F.L.1    Sales, V.S.F.2    Sousa, L.R.3    Watanabe, M.A.E.4
  • 30
    • 0037118911 scopus 로고    scopus 로고
    • Activation of RNA-dependent protein kinase and nuclear factor-kB by regulatory RNA from lipopolysaccharide-stimulated macrophages: Implications for cytokine production
    • De Lucca FL, Serrano SV, Souza LR, Watanabe MAE. (2002). Activation of RNA-dependent protein kinase and nuclear factor-kB by regulatory RNA from lipopolysaccharide-stimulated macrophages: implications for cytokine production. European Journal of Pharmacology. 450: 85-89.
    • (2002) European Journal of Pharmacology , vol.450 , pp. 85-89
    • De Lucca, F.L.1    Serrano, S.V.2    Souza, L.R.3    Watanabe, M.A.E.4
  • 31
    • 0038757561 scopus 로고    scopus 로고
    • Regulatory RNA induces the production of IFN-gamma, but not IL-4 in human lymphocytes: Role of RNA-dependent protein kinase (PKR) and NF-kappaB
    • De Lucca FL, Sales VSF, Sousa LR, Murad JM, Watanabe MAE. (2003). Regulatory RNA induces the production of IFN-gamma, but not IL-4 in human lymphocytes: role of RNA-dependent protein kinase (PKR) and NF-kappaB. Molecular and Cellular Biochemistry. 247: 211-217.
    • (2003) Molecular and Cellular Biochemistry , vol.247 , pp. 211-217
    • De Lucca, F.L.1    Sales, V.S.F.2    Sousa, L.R.3    Murad, J.M.4    Watanabe, M.A.E.5
  • 33
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C. (2004). Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science. 303: 1529-1531.
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis e Sousa, C.5
  • 35
    • 1442264796 scopus 로고    scopus 로고
    • The protein kinase PKR: A molecular clock that sequentially activates survival and death programs
    • Donzé O, Deng J, Curran J, Sladek R, Picard D, Sonenberg N. (2004). The protein kinase PKR: a molecular clock that sequentially activates survival and death programs. The EMBO Journal. 23: 564-571.
    • (2004) The EMBO Journal , vol.23 , pp. 564-571
    • Donzé, O.1    Deng, J.2    Curran, J.3    Sladek, R.4    Picard, D.5    Sonenberg, N.6
  • 36
    • 0018746793 scopus 로고
    • Some perspectives on the transfer of cell-mediated immunity by immune-RNA
    • Dray S, Braun DP. (1979). Some perspectives on the transfer of cell-mediated immunity by immune-RNA. Molecular and Cellular Biochemistry. 25: 15-30.
    • (1979) Molecular and Cellular Biochemistry , vol.25 , pp. 15-30
    • Dray, S.1    Braun, D.P.2
  • 38
    • 0035656688 scopus 로고    scopus 로고
    • Non-coding RNA genes and the modern RNA world
    • Eddy SR. (2001). Non-coding RNA genes and the modern RNA world. Nature Reviews Genetics. 2: 919-929.
    • (2001) Nature Reviews Genetics , vol.2 , pp. 919-929
    • Eddy, S.R.1
  • 39
    • 18144367709 scopus 로고    scopus 로고
    • Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription
    • Endo-Munoz L, Warby T, Harrich D, McMillan NA. (2005). Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription. Virology Journal. 2: 17.
    • (2005) Virology Journal , vol.2 , pp. 17
    • Endo-Munoz, L.1    Warby, T.2    Harrich, D.3    McMillan, N.A.4
  • 42
    • 0141483742 scopus 로고    scopus 로고
    • Transport of dsRNA into cells by the transmembrane protein SID-1
    • Feinberg EH, Hunter CP. (2003). Transport of dsRNA into cells by the transmembrane protein SID-1. Science. 301: 1545-1547.
    • (2003) Science , vol.301 , pp. 1545-1547
    • Feinberg, E.H.1    Hunter, C.P.2
  • 43
    • 0026653870 scopus 로고
    • Identification of double-stranded RNA binding domains in interferon-induced double-stranded RNA-activated p68 kinase
    • Feng GS, Chong K, Kumar A, Williams BRG. (1992). Identification of double-stranded RNA binding domains in interferon-induced double-stranded RNA-activated p68 kinase. Proceedings of the National Academy of Sciences USA. 89: 5447-5451.
    • (1992) Proceedings of the National Academy of Sciences USA , vol.89 , pp. 5447-5451
    • Feng, G.S.1    Chong, K.2    Kumar, A.3    Williams, B.R.G.4
  • 44
    • 0034192148 scopus 로고    scopus 로고
    • Proteins binding to duplexed RNA: One motif, multiple functions
    • Fierro-Monti I, Mathews MB. (2000). Proteins binding to duplexed RNA: one motif, multiple functions. Trends in Biochemical Sciences. 255: 241-246.
    • (2000) Trends in Biochemical Sciences , vol.255 , pp. 241-246
    • Fierro-Monti, I.1    Mathews, M.B.2
  • 45
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 391: 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 46
    • 0344731406 scopus 로고    scopus 로고
    • Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB
    • Gil J, Alcami J, Esteban M. (1999). Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB. Molecular and Cellular Biology. 19: 4653-4663.
    • (1999) Molecular and Cellular Biology , vol.19 , pp. 4653-4663
    • Gil, J.1    Alcami, J.2    Esteban, M.3
  • 47
    • 0034084338 scopus 로고    scopus 로고
    • Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): Mechanism of action
    • Gil J, Esteban M. (2000). Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action. Apoptosis. 5: 107-114.
    • (2000) Apoptosis , vol.5 , pp. 107-114
    • Gil, J.1    Esteban, M.2
  • 48
    • 0034721082 scopus 로고    scopus 로고
    • The interferon-induced protein kinase (PKR) triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-alpha receptors
    • Gil J, Esteban M. (2000). The interferon-induced protein kinase (PKR) triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-alpha receptors. Oncogene. 19: 3665-3674.
    • (2000) Oncogene , vol.19 , pp. 3665-3674
    • Gil, J.1    Esteban, M.2
  • 49
    • 0037048685 scopus 로고    scopus 로고
    • Caspase 9 activation by the dsRNA-dependent protein kinase, PKR: Molecular mechanism and relevance
    • Gil J, Garcia MA, Esbeban M. (2002). Caspase 9 activation by the dsRNA-dependent protein kinase, PKR: molecular mechanism and relevance. FEBS Letters. 529: 249-255.
    • (2002) FEBS Letters , vol.529 , pp. 249-255
    • Gil, J.1    Garcia, M.A.2    Esbeban, M.3
  • 51
    • 0032851620 scopus 로고    scopus 로고
    • Apoptosis and HIV infection: T-cells fiddle while the immune system burns
    • Goldberg B, Sticker RB. (1999). Apoptosis and HIV infection: T-cells fiddle while the immune system burns. Immunology Letters. 701: 5-8.
    • (1999) Immunology Letters , vol.701 , pp. 5-8
    • Goldberg, B.1    Sticker, R.B.2
  • 52
    • 0033380647 scopus 로고    scopus 로고
    • Programmed cell death as a mechanism of CD4 and CD8 T cell deletion in AIDS. Molecular control and effect of highly active anti-retroviral therapy
    • Gougeon ML, Montagnier L. (1999). Programmed cell death as a mechanism of CD4 and CD8 T cell deletion in AIDS. Molecular control and effect of highly active anti-retroviral therapy. Annals New York Academy of Sciences. 887: 199-212.
    • (1999) Annals New York Academy of Sciences , vol.887 , pp. 199-212
    • Gougeon, M.L.1    Montagnier, L.2
  • 54
    • 3543078012 scopus 로고    scopus 로고
    • HIV and SIV CTL escape: Implications for vaccine design
    • Goulder PJ, Watkins DI. (2004). HIV and SIV CTL escape: implications for vaccine design. Nature Reviews Immunology. 4: 630-640.
    • (2004) Nature Reviews Immunology , vol.4 , pp. 630-640
    • Goulder, P.J.1    Watkins, D.I.2
  • 55
    • 0027105279 scopus 로고
    • Two RNA binding motifs in the dsRNA-activated protein kinase, DAI
    • Green SR, Mathews MB. (1992). Two RNA binding motifs in the dsRNA-activated protein kinase, DAI. Genes and Development. 6: 2478-2490.
    • (1992) Genes and Development , vol.6 , pp. 2478-2490
    • Green, S.R.1    Mathews, M.B.2
  • 56
    • 0031716920 scopus 로고    scopus 로고
    • RNA binding and modulation of PKR activity
    • Gunnery S, Mathews MB. (1998). RNA binding and modulation of PKR activity. Methods. 15: 189-198.
    • (1998) Methods , vol.15 , pp. 189-198
    • Gunnery, S.1    Mathews, M.B.2
  • 57
    • 0029020282 scopus 로고
    • Protein kinases 6. The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification
    • Hanks SK, Hunter T. (1995). Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. The FASEB Journal. 9: 576-596.
    • (1995) The FASEB Journal , vol.9 , pp. 576-596
    • Hanks, S.K.1    Hunter, T.2
  • 58
    • 0023885305 scopus 로고
    • The protein kinase family: Conserved features and deduced phylogeny of catalytic domains
    • Hanks SK, Quinn AM, Hunter T. (1988). The protein kinase family: conserved features and deduced phylogeny of catalytic domains. Science. 241: 42-52.
    • (1988) Science , vol.241 , pp. 42-52
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 60
    • 0031964793 scopus 로고    scopus 로고
    • Distinct mechanisms trigger apoptosis in human immunodeficiency virus type 1-infected and in uninfected bystander T lymphocytes
    • Herbein G, Van Lint C, Lovett JL, Verdin E. (1998). Distinct mechanisms trigger apoptosis in human immunodeficiency virus type 1-infected and in uninfected bystander T lymphocytes. Journal of Virology. 721: 660-670.
    • (1998) Journal of Virology , vol.721 , pp. 660-670
    • Herbein, G.1    Van Lint, C.2    Lovett, J.L.3    Verdin, E.4
  • 62
    • 1242269845 scopus 로고    scopus 로고
    • Multiple effects of HIV-1 trans-activator protein on the pathogenesis of HIV-1 infection
    • Huigen MC, Kamp W, Nottet HS. (2004). Multiple effects of HIV-1 trans-activator protein on the pathogenesis of HIV-1 infection. European Journal of Clinical Investigation. 34: 57-66.
    • (2004) European Journal of Clinical Investigation , vol.34 , pp. 57-66
    • Huigen, M.C.1    Kamp, W.2    Nottet, H.S.3
  • 64
    • 17644399432 scopus 로고    scopus 로고
    • Two mechanisms of caspase 9 processing in double-stranded RNA- and virus-triggered apoptosis
    • Iordanov MS, Ryabinina OP, Schneider P, Magun BE. (2005). Two mechanisms of caspase 9 processing in double-stranded RNA- and virus-triggered apoptosis. Apoptosis. 10: 153-166.
    • (2005) Apoptosis , vol.10 , pp. 153-166
    • Iordanov, M.S.1    Ryabinina, O.P.2    Schneider, P.3    Magun, B.E.4
  • 66
    • 0030013325 scopus 로고    scopus 로고
    • 2-Aminopurine selectively inhibits splicing of tumor necrosis factor alpha mRNA
    • Jarrous N, Osman F, Kaempfer R. (1996). 2-Aminopurine selectively inhibits splicing of tumor necrosis factor alpha mRNA. Molecular and Cellular Biology. 16: 2814-2822.
    • (1996) Molecular and Cellular Biology , vol.16 , pp. 2814-2822
    • Jarrous, N.1    Osman, F.2    Kaempfer, R.3
  • 67
    • 0038714270 scopus 로고    scopus 로고
    • Poly (I-C)-induced Toll-like receptor 3 (TLR3) mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR
    • Jiang Z, Zamanian-Daryoush M, Nie H, Silva AM, Williams BR, Li X. (2003). Poly (I-C)-induced Toll-like receptor 3 (TLR3) mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR. The Journal Biological Chemistry. 278: 16713-16719.
    • (2003) The Journal Biological Chemistry , vol.278 , pp. 16713-16719
    • Jiang, Z.1    Zamanian-Daryoush, M.2    Nie, H.3    Silva, A.M.4    Williams, B.R.5    Li, X.6
  • 68
    • 0348133608 scopus 로고    scopus 로고
    • RNA sensors: Novel regulators of gene expression
    • Kaempfer R. (2003). RNA sensors: novel regulators of gene expression. EMBO Reports. 4: 1043-1047.
    • (2003) EMBO Reports , vol.4 , pp. 1043-1047
    • Kaempfer, R.1
  • 69
    • 0031903406 scopus 로고    scopus 로고
    • Role of the Fas/Fas ligand apoptotic pathway in human immunodeficiency virus type 1disease
    • Kaplan D, Sieg S. (1998). Role of the Fas/Fas ligand apoptotic pathway in human immunodeficiency virus type 1disease. Journal of Virology. 72: 6279-6282.
    • (1998) Journal of Virology , vol.72 , pp. 6279-6282
    • Kaplan, D.1    Sieg, S.2
  • 70
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-κB activity
    • Karin M, Ben-Neriah Y. (2000). Phosphorylation meets ubiquitination: the control of NF-κB activity. Annual Review of Immunology 18: 621-663.
    • (2000) Annual Review of Immunology , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 71
    • 0032692634 scopus 로고    scopus 로고
    • Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: A new role for an old actor
    • Kaufman RJ. (1999). Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor. Proceedings of the National Academy of Science USA. 96: 11693-11695.
    • (1999) Proceedings of the National Academy of Science USA , vol.96 , pp. 11693-11695
    • Kaufman, R.J.1
  • 73
    • 0034702174 scopus 로고    scopus 로고
    • Human breast cancer cells contain elevated levels and activity of the protein kinase, PKR
    • Kim SH, Forman AP, Mathews MB, Gunnery S. (2000). Human breast cancer cells contain elevated levels and activity of the protein kinase, PKR. Oncogene. 19: 3086-3094.
    • (2000) Oncogene , vol.19 , pp. 3086-3094
    • Kim, S.H.1    Forman, A.P.2    Mathews, M.B.3    Gunnery, S.4
  • 74
    • 0037069935 scopus 로고    scopus 로고
    • Neoplastic progression in melanoma and colon cancer is associated with increased expression and activity of the interferon-inducible protein kinase, PKR
    • Kim SH, Gunnery S, Choe JK, Mathews MB. (2002). Neoplastic progression in melanoma and colon cancer is associated with increased expression and activity of the interferon-inducible protein kinase, PKR. Oncogene. 21: 8741-8748.
    • (2002) Oncogene , vol.21 , pp. 8741-8748
    • Kim, S.H.1    Gunnery, S.2    Choe, J.K.3    Mathews, M.B.4
  • 76
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T. (2001). Identification of novel genes coding for small expressed RNAs. Science. 294: 853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 78
    • 17144431791 scopus 로고    scopus 로고
    • Double-stranded RNA-activated protein kinase is required for the LPS-induced activation of STAT1 inflammatory signaling in rat brain glial cells
    • Lee JH, Park EJ, Kim OS, Kim HY, Joe EY, Jou I. (2005). Double-stranded RNA-activated protein kinase is required for the LPS-induced activation of STAT1 inflammatory signaling in rat brain glial cells. Glia. 50: 66-79.
    • (2005) Glia , vol.50 , pp. 66-79
    • Lee, J.H.1    Park, E.J.2    Kim, O.S.3    Kim, H.Y.4    Joe, E.Y.5    Jou, I.6
  • 79
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee RC, Ambros V. (2001). An extensive class of small RNAs in Caenorhabditis elegans. Science. 294: 862-864.
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 81
    • 0026010912 scopus 로고
    • Activation of the double-stranded RNA-dependent eIF-2 alpha kinase by cellular RNA from 3T3-F442A cells
    • Li J, Petryshyn RA. (1991). Activation of the double-stranded RNA-dependent eIF-2 alpha kinase by cellular RNA from 3T3-F442A cells. European Journal of Biochemistry. 195: 41-48.
    • (1991) European Journal of Biochemistry , vol.195 , pp. 41-48
    • Li, J.1    Petryshyn, R.A.2
  • 82
    • 20444422574 scopus 로고    scopus 로고
    • Mechanisms for HIV Tat upregulation of IL-10 and other cytokine expression: Kinase signaling and PKR-mediated immune response
    • Li JC, Le DC, Cheung BK, Lau AS. (2005). Mechanisms for HIV Tat upregulation of IL-10 and other cytokine expression: kinase signaling and PKR-mediated immune response. FEBS Letters. 579: 3055-3062.
    • (2005) FEBS Letters , vol.579 , pp. 3055-3062
    • Li, J.C.1    Le, D.C.2    Cheung, B.K.3    Lau, A.S.4
  • 83
    • 0026674886 scopus 로고
    • Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction
    • Liang P, Pardee AB. (1992). Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science. 257: 967-971.
    • (1992) Science , vol.257 , pp. 967-971
    • Liang, P.1    Pardee, A.B.2
  • 86
    • 0026713151 scopus 로고
    • Interactions between double-stranded RNA regulators and the protein kinase DAI
    • Manche L, Green SR, Schmedt C, Mathews MB. (1992). Interactions between double-stranded RNA regulators and the protein kinase DAI. Molecular and Cellular Biology. 12: 5238-5248.
    • (1992) Molecular and Cellular Biology , vol.12 , pp. 5238-5248
    • Manche, L.1    Green, S.R.2    Schmedt, C.3    Mathews, M.B.4
  • 87
    • 0034882101 scopus 로고    scopus 로고
    • The evolution of controlled multitasked gene networks: The role of introns and other noncoding RNAs in the development of complex organisms
    • Mattick JS, Gagen MJ. (2001). The evolution of controlled multitasked gene networks: the role of introns and other noncoding RNAs in the development of complex organisms. Molecular Biology Evolution. 18: 1611-1630.
    • (2001) Molecular Biology Evolution , vol.18 , pp. 1611-1630
    • Mattick, J.S.1    Gagen, M.J.2
  • 88
    • 0035195942 scopus 로고    scopus 로고
    • Non-coding RNAs: The architects of eukaryotic complexity
    • Mattick JS. (2001). Non-coding RNAs: the architects of eukaryotic complexity. EMBO Reports. 2: 986-991.
    • (2001) EMBO Reports , vol.2 , pp. 986-991
    • Mattick, J.S.1
  • 89
    • 1842584883 scopus 로고    scopus 로고
    • RNA regulation: A new genetics?
    • Mattick JS. (2004). RNA regulation: a new genetics? Nature Reviews Genetics. 5: 316-323.
    • (2004) Nature Reviews Genetics , vol.5 , pp. 316-323
    • Mattick, J.S.1
  • 93
    • 0036023470 scopus 로고    scopus 로고
    • Non-coding ribonucleic acids - A class of their own?
    • Michel, U. (2002). Non-coding ribonucleic acids - a class of their own? International Review of Cytology. 218: 143-219.
    • (2002) International Review of Cytology , vol.218 , pp. 143-219
    • Michel, U.1
  • 95
    • 0028852619 scopus 로고
    • Platelet-derived growth factor signal transduction through the interferon-inducible kinase PKR. Immediate early gene induction
    • Mundschau LJ, Faller DV. (1995). Platelet-derived growth factor signal transduction through the interferon-inducible kinase PKR. Immediate early gene induction. The Journal of Biological Chemistry. 270: 3100-3106.
    • (1995) The Journal of Biological Chemistry , vol.270 , pp. 3100-3106
    • Mundschau, L.J.1    Faller, D.V.2
  • 96
    • 10944220731 scopus 로고    scopus 로고
    • A point mutation in the RNA-binding domain I results in decrease of PKR activation in acute lymphoblastic leukemia
    • Murad JM, Tone LG, de Souza LR, De Lucca FL. (2005). A point mutation in the RNA-binding domain I results in decrease of PKR activation in acute lymphoblastic leukemia. Blood Cells, Molecules and Diseases. 34: 1-5.
    • (2005) Blood Cells, Molecules and Diseases , vol.34 , pp. 1-5
    • Murad, J.M.1    Tone, L.G.2    de Souza, L.R.3    De Lucca, F.L.4
  • 98
    • 0036488945 scopus 로고    scopus 로고
    • The 3′-untranslated regions of cytoskeletal muscle mRNAs inhibit translation by activating the double-stranded RNA-dependent protein kinase PKR
    • Nussbaum JM, Gunnery S, Mathews MB. (2002). The 3′-untranslated regions of cytoskeletal muscle mRNAs inhibit translation by activating the double-stranded RNA-dependent protein kinase PKR. Nucleic Acids Research. 30: 1205-1212.
    • (2002) Nucleic Acids Research , vol.30 , pp. 1205-1212
    • Nussbaum, J.M.1    Gunnery, S.2    Mathews, M.B.3
  • 99
    • 4043060710 scopus 로고    scopus 로고
    • Correlates of immune protection in HIV-1 infection: What we know, what we don't know, what we should know
    • Pantaleo G, Koup RA. (2004). Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know. Nature Medicine. 10: 806-810.
    • (2004) Nature Medicine , vol.10 , pp. 806-810
    • Pantaleo, G.1    Koup, R.A.2
  • 101
    • 0026352593 scopus 로고
    • RNA-medilited transfer of cellular immunity to a synthetic env antigen of the human immunodeficiency virus (HIV-1)
    • Passos GAS Jr, De Lucca FL. (1991). RNA-medilited transfer of cellular immunity to a synthetic env antigen of the human immunodeficiency virus (HIV-1). Molecular and Cellular Biochemistry. 108: 1-8.
    • (1991) Molecular and Cellular Biochemistry. , vol.108 , pp. 1-8
    • Passos Jr., G.A.S.1    De Lucca, F.L.2
  • 102
    • 0026686791 scopus 로고
    • Identification of dsRNA binding domain of human, interferon-inducible protein kinase
    • Patel RC, Sen GC. (1992). Identification of dsRNA binding domain of human, interferon-inducible protein kinase. The Journal of Biological Chemistry. 267: 7871-7876.
    • (1992) The Journal of Biological Chemistry , vol.267 , pp. 7871-7876
    • Patel, R.C.1    Sen, G.C.2
  • 103
    • 0017659715 scopus 로고
    • Preliminary studies of specific immunotherapy of cancer with immune RNA
    • Pilch YH, Ramming KP, DeKernion JB. (1977). Preliminary studies of specific immunotherapy of cancer with immune RNA. Cancer. 40: 2747-2757.
    • (1977) Cancer , vol.40 , pp. 2747-2757
    • Pilch, Y.H.1    Ramming, K.P.2    DeKernion, J.B.3
  • 105
    • 0345477304 scopus 로고    scopus 로고
    • Genetic Organization of HIV
    • S. Ed New York, Plenum Press
    • Ratner L. (1996). Genetic Organization of HIV. In: Gupta, S. Ed, Immunology of HIV Infection. New York, Plenum Press, pp 3-22.
    • (1996) Immunology of HIV Infection , pp. 3-22
    • Ratner, L.1
  • 106
    • 0027135426 scopus 로고
    • RNA from LPS-stimulated macrophages induces the release of tumor necrosis factor α and interleukin-1 by resident macrophages
    • Ribeiro RA, De Lucca FL, Flares CA, Cunha FQ, Ferreira SH. (1993). RNA from LPS-stimulated macrophages induces the release of tumor necrosis factor α and interleukin-1 by resident macrophages. Mediators of Inflammation. 2: 435-442.
    • (1993) Mediators of Inflammation , vol.2 , pp. 435-442
    • Ribeiro, R.A.1    De Lucca, F.L.2    Flares, C.A.3    Cunha, F.Q.4    Ferreira, S.H.5
  • 107
    • 0029117104 scopus 로고
    • Partial characterization of the RNA from LPS-stimulated macrophages that induces the release of chemotactic cytokines by resident macrophages
    • Ribeiro RA, Flores CA, Cunha FQ, Ferreira SH, Dc Lucca FL. (1995). Partial characterization of the RNA from LPS-stimulated macrophages that induces the release of chemotactic cytokines by resident macrophages. Molecular and Cellular Biochemistry. 148: 105-113.
    • (1995) Molecular and Cellular Biochemistry , vol.148 , pp. 105-113
    • Ribeiro, R.A.1    Flores, C.A.2    Cunha, F.Q.3    Ferreira, S.H.4    Dc Lucca, F.L.5
  • 108
    • 0019467317 scopus 로고
    • In vivo and in vitro effects of xenogeneic immune ribonucleic acid in patients with advanced renal cell carcinoma: A phase I study
    • Richie JP, Wang BS, Steele Jr GD, Wilson RE, Mannick JA. (1981). In vivo and in vitro effects of xenogeneic immune ribonucleic acid in patients with advanced renal cell carcinoma: a phase I study. Journal of Urology. 126: 24-28.
    • (1981) Journal of Urology , vol.126 , pp. 24-28
    • Richie, J.P.1    Wang, B.S.2    Steele Jr, G.D.3    Wilson, R.E.4    Mannick, J.A.5
  • 110
    • 0030440591 scopus 로고    scopus 로고
    • The regulation of the protein kinase PKR by RNA
    • Robertson HD, Mathews MB. (1996). The regulation of the protein kinase PKR by RNA. Biochimie. 78: 909-914.
    • (1996) Biochimie , vol.78 , pp. 909-914
    • Robertson, H.D.1    Mathews, M.B.2
  • 112
    • 0032967979 scopus 로고    scopus 로고
    • Abnormal levels and minimal activity of the dsRNA-activated protein kinase, PKR, in breast carcinoma cells
    • Savinova O, Joshi B, Jagus R. (1999). Abnormal levels and minimal activity of the dsRNA-activated protein kinase, PKR, in breast carcinoma cells. The International Journal of Biochemistry and Cell Biology. 31: 175-189.
    • (1999) The International Journal of Biochemistry and Cell Biology , vol.31 , pp. 175-189
    • Savinova, O.1    Joshi, B.2    Jagus, R.3
  • 113
    • 0028042337 scopus 로고
    • HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes
    • Silverman RH. (1994). HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes. Virology. 204: 823-827.
    • (1994) Virology , vol.204 , pp. 823-827
    • Silverman, R.H.1
  • 114
    • 0031891869 scopus 로고    scopus 로고
    • Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase
    • Srivastava SP, Kumar KU, Kaufman RJ. (1998). Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase. The Journal of Biological Chemistry. 273: 2416-2423.
    • (1998) The Journal of Biological Chemistry , vol.273 , pp. 2416-2423
    • Srivastava, S.P.1    Kumar, K.U.2    Kaufman, R.J.3
  • 116
    • 0019469631 scopus 로고
    • Results of xenogeneic I-RNA therapy in patients with metastatic renal cell carcinoma
    • Steele G Jr, Wang BS, Richie JP, Ervin T, Yankee R, Mannick JA. (1982). Results of xenogeneic I-RNA therapy in patients with metastatic renal cell carcinoma. Cancer. 47: 1286-1288.
    • (1982) Cancer , vol.47 , pp. 1286-1288
    • Steele Jr., G.1    Wang, B.S.2    Richie, J.P.3    Ervin, T.4    Yankee, R.5    Mannick, J.A.6
  • 117
    • 2542490238 scopus 로고    scopus 로고
    • Virus-host interactions: Role of HIV proteins Vif, Tat, and Rev
    • Strebel K. (2003). Virus-host interactions: role of HIV proteins Vif, Tat, and Rev. AIDS. 17: S25-34.
    • (2003) AIDS , vol.17
    • Strebel, K.1
  • 118
    • 0036262226 scopus 로고    scopus 로고
    • Beyond the proteome: Non-coding regulatory RNAs
    • reviews 0005.1-0005.8
    • Szymanski M, Barciszewski J. (2002). Beyond the proteome: non-coding regulatory RNAs. Genome Biology. 3 (5): reviews 0005.1-0005.8.
    • (2002) Genome Biology , vol.3 , Issue.5
    • Szymanski, M.1    Barciszewski, J.2
  • 119
    • 0029842883 scopus 로고    scopus 로고
    • Possible involvement of double-stranded RNA-activated protein kinase in cell death by influenza virus infection
    • Takizawa T, Ohashi K, Nakanishi Y. (1996). Possible involvement of double-stranded RNA-activated protein kinase in cell death by influenza virus infection. Journal of Virology. 70: 8128-8132.
    • (1996) Journal of Virology , vol.70 , pp. 8128-8132
    • Takizawa, T.1    Ohashi, K.2    Nakanishi, Y.3
  • 120
    • 0033023069 scopus 로고    scopus 로고
    • Double-stranded RNA-activated protein kinase (PKR) fused to green fluorescent protein induces apoptosis of human embryonic kidney cells: Possible role in the Fas signaling pathway
    • Takizawa T, Tatematsu C, Nakanishi Y. (1999). Double-stranded RNA-activated protein kinase (PKR) fused to green fluorescent protein induces apoptosis of human embryonic kidney cells: possible role in the Fas signaling pathway. Journal of Biochemistry. 125: 391-398.
    • (1999) Journal of Biochemistry , vol.125 , pp. 391-398
    • Takizawa, T.1    Tatematsu, C.2    Nakanishi, Y.3
  • 121
    • 0032811002 scopus 로고    scopus 로고
    • The emerging role of the interferon-induced PKR protein kinase as an apoptotic effector: A new face of death?
    • Tan SL, Katze MG. (1999). The emerging role of the interferon-induced PKR protein kinase as an apoptotic effector: a new face of death? Journal of Interferon and Cytokine Research. 19: 543-554.
    • (1999) Journal of Interferon and Cytokine Research , vol.19 , pp. 543-554
    • Tan, S.L.1    Katze, M.G.2
  • 124
    • 0026716253 scopus 로고
    • cDNA structure, expression, and regulation of PKR from human cells
    • Thomis DC, Samuel CE. (1992). cDNA structure, expression, and regulation of PKR from human cells. Virology. 188: 33-46.
    • (1992) Virology , vol.188 , pp. 33-46
    • Thomis, D.C.1    Samuel, C.E.2
  • 125
    • 0035971150 scopus 로고    scopus 로고
    • Functional characterization of and cooperation between the double-stranded RNA-binding motifs of the protein kinase PKR
    • Tian B, Mathews MB. (2001). Functional characterization of and cooperation between the double-stranded RNA-binding motifs of the protein kinase PKR. The Journal of Biological Chemistry. 276: 9936-9944.
    • (2001) The Journal of Biological Chemistry , vol.276 , pp. 9936-9944
    • Tian, B.1    Mathews, M.B.2
  • 127
    • 0037418822 scopus 로고    scopus 로고
    • Antitumor activity induced by regulatory RNA: Possible role of RNA-dependent protein kinase and nuclear factor-kappaB
    • Watanabe MAE, Souza LR, Murad JM, De Lucca FL. (2003). Antitumor activity induced by regulatory RNA: possible role of RNA-dependent protein kinase and nuclear factor-kappaB. European Journal of Pharmacology. 465: 205-210.
    • (2003) European Journal of Pharmacology , vol.465 , pp. 205-210
    • Watanabe, M.A.E.1    Souza, L.R.2    Murad, J.M.3    De Lucca, F.L.4
  • 128
    • 0343852938 scopus 로고    scopus 로고
    • Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways
    • Wong AH, Tam NW, Yang YL, Cuddihy AR, Li S, Kirchhoff S, Hauser H, Decker T, Koromilas AE. (1997). Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways. The EMBO Journal. 16: 1291-1304.
    • (1997) The EMBO Journal , vol.16 , pp. 1291-1304
    • Wong, A.H.1    Tam, N.W.2    Yang, Y.L.3    Cuddihy, A.R.4    Li, S.5    Kirchhoff, S.6    Hauser, H.7    Decker, T.8    Koromilas, A.E.9
  • 129
    • 0041468870 scopus 로고    scopus 로고
    • CD8 T cell responses to infectious pathogens
    • Wong P, Pamer EG. (2003). CD8 T cell responses to infectious pathogens. Annual Review of Immunology. 21: 29-70.
    • (2003) Annual Review of Immunology , vol.21 , pp. 29-70
    • Wong, P.1    Pamer, E.G.2
  • 131
    • 0034687782 scopus 로고    scopus 로고
    • Straightening of bulged RNA by the double-stranded RNA-binding domain from the protein kinase PKR
    • Zheng X, Bevilacqua PC. (2000). Straightening of bulged RNA by the double-stranded RNA-binding domain from the protein kinase PKR. Proceedings of the National Academy of Sciences USA. 97: 14162-14167.
    • (2000) Proceedings of the National Academy of Sciences USA , vol.97 , pp. 14162-14167
    • Zheng, X.1    Bevilacqua, P.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.