-
1
-
-
0030725442
-
The double-stranded RNA-dependent protein kinase PKR: Structure and function
-
M.J. Clemens, A. Elia, The double-stranded RNA-dependent protein kinase PKR: structure and function, J. Interferon Cytokine Res. 17 (1997) 503-524.
-
(1997)
J. Interferon Cytokine Res.
, vol.17
, pp. 503-524
-
-
Clemens, M.J.1
Elia, A.2
-
2
-
-
0030440591
-
The regulation of the protein kinase PKR by RNA
-
H.D. Robertson, M.B. Mathews, The regulation of the protein kinase PKR by RNA, Biochimie 78 (1996) 909-914.
-
(1996)
Biochimie
, vol.78
, pp. 909-914
-
-
Robertson, H.D.1
Mathews, M.B.2
-
3
-
-
0029968705
-
Initiation of protein synthesis in eukaryotic cells
-
V.M. Pain, Initiation of protein synthesis in eukaryotic cells, Eur. J. Biochem. 236 (1996) 747-771.
-
(1996)
Eur. J. Biochem.
, vol.236
, pp. 747-771
-
-
Pain, V.M.1
-
4
-
-
0030267336
-
The eIF2α kinases and the control of protein synthesis
-
C. DeHaro, The eIF2α kinases and the control of protein synthesis, FASEB J. 10 (1996) 1378-1387.
-
(1996)
FASEB J.
, vol.10
, pp. 1378-1387
-
-
Deharo, C.1
-
5
-
-
0028290902
-
The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis
-
S.B. Lee, M. Esteban, The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis, Virol. 199 (1994) 491-496.
-
(1994)
Virol.
, vol.199
, pp. 491-496
-
-
Lee, S.B.1
Esteban, M.2
-
6
-
-
0343812093
-
The apoptosis pathway triggered by the interferon-induced protein kinase, PKR, requires the third basic domain, initiates upstream of Bcl-2, and involves ICE-like proteases
-
S.B. Lee, D. Rodriguez, J.R. Rodriguez, M. Esteban, The apoptosis pathway triggered by the interferon-induced protein kinase, PKR, requires the third basic domain, initiates upstream of Bcl-2, and involves ICE-like proteases, Virology 231 (1997) 81-88.
-
(1997)
Virology
, vol.231
, pp. 81-88
-
-
Lee, S.B.1
Rodriguez, D.2
Rodriguez, J.R.3
Esteban, M.4
-
7
-
-
0030992545
-
A dsRNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis
-
S.D. Der, Y.L. Yang, C. Weissman, B.R. Williams, A dsRNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis, Proc. Natl. Acad. Sci. 94 (1997) 3279-3283.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 3279-3283
-
-
Der, S.D.1
Yang, Y.L.2
Weissman, C.3
Williams, B.R.4
-
8
-
-
0031891869
-
Phosphorylation of eIF2 mediates apoptosis in response to activation of PKR
-
S.P. Srivastava, K.U. Kumar, R.J. Kaufman, Phosphorylation of eIF2 mediates apoptosis in response to activation of PKR, J. Biol. Chem. 273 (1998) 2416-2423.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 2416-2423
-
-
Srivastava, S.P.1
Kumar, K.U.2
Kaufman, R.J.3
-
9
-
-
25044477096
-
Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis and employs the death signal transducer FADD
-
in press
-
S. Balachandran, N. Kim, W.-C. Yeh, T.W. Mak, K. Bhalla, G.N. Barber, Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis and employs the death signal transducer FADD. EMBO J., in press.
-
EMBO J.
-
-
Balachandran, S.1
Kim, N.2
Yeh, W.-C.3
Mak, T.W.4
Bhalla, K.5
Barber, G.N.6
-
10
-
-
0033045295
-
PKR, apoptosis and cancer
-
R. Jagus, B. Joshi, G.N. Barber, PKR, apoptosis and cancer. Int. J. Biochem. Cell Biol., 31 (1999) 123-138.
-
(1999)
Int. J. Biochem. Cell Biol.
, vol.31
, pp. 123-138
-
-
Jagus, R.1
Joshi, B.2
Barber, G.N.3
-
11
-
-
0026701570
-
Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase
-
A.E. Koromilas, S. Roy, G.N. Barber, M. Katze, N. Sonenberg, Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase, Science 257 (1992) 1685-1689.
-
(1992)
Science
, vol.257
, pp. 1685-1689
-
-
Koromilas, A.E.1
Roy, S.2
Barber, G.N.3
Katze, M.4
Sonenberg, N.5
-
12
-
-
0027396813
-
Interferon-induced dsRNA activated protein kinase: Antiviral and antitumoral functions
-
E. Meurs, J. Galabru, G.N. Barber, M.G. Katze, A.G. Hovanessian, Interferon-induced dsRNA activated protein kinase: antiviral and antitumoral functions, Proc. Natl. Acad. Sci. 90 (1993) 232-236.
-
(1993)
Proc. Natl. Acad. Sci.
, vol.90
, pp. 232-236
-
-
Meurs, E.1
Galabru, J.2
Barber, G.N.3
Katze, M.G.4
Hovanessian, A.G.5
-
13
-
-
0029061555
-
Mutants of PKR lacking dsRNA binding domain I can act as transdominant inhibitors and induce malignant transformation
-
G. Barber, M. Wambach, S. Thompson, R. Jagus, M.G. Katze, Mutants of PKR lacking dsRNA binding domain I can act as transdominant inhibitors and induce malignant transformation, Mol. Cell. Biol. 15 (1995) 3138-3146.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3138-3146
-
-
Barber, G.1
Wambach, M.2
Thompson, S.3
Jagus, R.4
Katze, M.G.5
-
14
-
-
0029122270
-
Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of PKR
-
G.N. Barber, R. Jagus, E.F. Meurs, A. Hovanessian, M.G. Katze, Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of PKR, J. Biol. Chem. 270 (1995) 17423-17428.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17423-17428
-
-
Barber, G.N.1
Jagus, R.2
Meurs, E.F.3
Hovanessian, A.4
Katze, M.G.5
-
15
-
-
0028211253
-
The 58-kDa inhibitor of PKR is a TPR protein with oncogenic properties
-
G.N. Barber, S. Thompson, T.G. Lee, T. Strom, R. Jagus, A. Darveau, M.G. Katze, The 58-kDa inhibitor of PKR is a TPR protein with oncogenic properties, Proc. Natl. Acad. Sci. 91 (1994) 4278-4282.
-
(1994)
Proc. Natl. Acad. Sci.
, vol.91
, pp. 4278-4282
-
-
Barber, G.N.1
Thompson, S.2
Lee, T.G.3
Strom, T.4
Jagus, R.5
Darveau, A.6
Katze, M.G.7
-
16
-
-
0029118217
-
Abrogation of translation initiation factor eIF-2 phosphorylation
-
O. Donze, R. Jagus, A.E. Koromilas, J.W.B. Hershey, N. Sonenberg, Abrogation of translation initiation factor eIF-2 phosphorylation, EMBO J. 14 (1995) 3828-3834.
-
(1995)
EMBO J.
, vol.14
, pp. 3828-3834
-
-
Donze, O.1
Jagus, R.2
Koromilas, A.E.3
Hershey, J.W.B.4
Sonenberg, N.5
-
17
-
-
0029590069
-
Deficient signaling in mice devoid of dsRNA-dependent protein kinase (PKR)
-
Y.-L. Yang, L.F.L. Reis, J. Pavlovic, A. Aguzzi, R. Schafer, A. Kumar, B.R.G. Williams, M. Aguet, C. Weissman, Deficient signaling in mice devoid of dsRNA-dependent protein kinase (PKR), EMBO J. 14 (1995) 6095-6106.
-
(1995)
EMBO J.
, vol.14
, pp. 6095-6106
-
-
Yang, Y.-L.1
Reis, L.F.L.2
Pavlovic, J.3
Aguzzi, A.4
Schafer, R.5
Kumar, A.6
Williams, B.R.G.7
Aguet, M.8
Weissman, C.9
-
18
-
-
0028978183
-
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
-
C. Deng, P. Zhang, J.W. Harper, S.J. Elledge, P. Leder, Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control, Cell 82 (1995) 675-684.
-
(1995)
Cell
, vol.82
, pp. 675-684
-
-
Deng, C.1
Zhang, P.2
Harper, J.W.3
Elledge, S.J.4
Leder, P.5
-
19
-
-
1842374435
-
Cyclin dependent kinase inhibitors
-
J.W. Harper, Cyclin dependent kinase inhibitors, Cancer Surv. 29 (1997) 91-107.
-
(1997)
Cancer Surv.
, vol.29
, pp. 91-107
-
-
Harper, J.W.1
-
20
-
-
0031306844
-
The regulation of cyclin-dependent kinase inhibitors (CKIs)
-
M. Peter, The regulation of cyclin-dependent kinase inhibitors (CKIs), Progr. Cell Cycle Res. 3 (1997) 99-108.
-
(1997)
Progr. Cell Cycle Res.
, vol.3
, pp. 99-108
-
-
Peter, M.1
-
21
-
-
0029658030
-
The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression
-
C. Missero, F. Di Cunto, H. Kiyokawa, A. Koff, G.P. Dotto, The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression, Genes Dev. 10 (1996) 3065-3075.
-
(1996)
Genes Dev.
, vol.10
, pp. 3065-3075
-
-
Missero, C.1
Di Cunto, F.2
Kiyokawa, H.3
Koff, A.4
Dotto, G.P.5
-
22
-
-
0027179117
-
Multiple steps in carcinogenesis involving alterations of multiple tumor suppressor genes
-
J. Yokota, T. Sugimura, Multiple steps in carcinogenesis involving alterations of multiple tumor suppressor genes, FASEB J. 7 (1993) 920-925.
-
(1993)
FASEB J.
, vol.7
, pp. 920-925
-
-
Yokota, J.1
Sugimura, T.2
-
23
-
-
0027272839
-
Expression of p68 protein kinase as recognized by the monoclonal antibody TJ4C4 during human fetal development
-
G.K. Haines, G. Ghadge, J.A. Radosevich, Expression of p68 protein kinase as recognized by the monoclonal antibody TJ4C4 during human fetal development, Tumor Biol. 14 (1993) 95-104.
-
(1993)
Tumor Biol.
, vol.14
, pp. 95-104
-
-
Haines, G.K.1
Ghadge, G.2
Radosevich, J.A.3
-
24
-
-
0026669650
-
Expression of PKR (p68) recognized by the monoclonal antibody TJ4C4 in human lung neoplasms
-
G.K. Haines, G.D. Ghadge, B. Thimmapaya, J.A. Radosevich, Expression of PKR (p68) recognized by the monoclonal antibody TJ4C4 in human lung neoplasms, Virch. Arch. B Cell Pathol. 62 (1992) 151-158.
-
(1992)
Virch. Arch. B Cell Pathol.
, vol.62
, pp. 151-158
-
-
Haines, G.K.1
Ghadge, G.D.2
Thimmapaya, B.3
Radosevich, J.A.4
-
25
-
-
0027383066
-
Expression of PKR(p68) in squamous cell carcinoma of the head and neck region
-
G.K. Haines, S. Becker, G. Ghadge, M. Kies, H. Pelzer, J.A. Radosevich, Expression of PKR(p68) in squamous cell carcinoma of the head and neck region, Arch. Otolaryngol. Head Neck Surg. 119 (1993) 1142-1147.
-
(1993)
Arch. Otolaryngol. Head Neck Surg.
, vol.119
, pp. 1142-1147
-
-
Haines, G.K.1
Becker, S.2
Ghadge, G.3
Kies, M.4
Pelzer, H.5
Radosevich, J.A.6
-
26
-
-
0027324680
-
Correlation of the expression of PKR (p68) with differentiation in head and neck squamous cell carcinoma
-
G.K. Haines, G.D. Ghadge, S. Becker, M. Kies, H. Pelzer, B. Thimmapaya, J.A. Radosevich, Correlation of the expression of PKR (p68) with differentiation in head and neck squamous cell carcinoma, Virch. Arch. B Cell Pathol. 63 (1993) 289-295.
-
(1993)
Virch. Arch. B Cell Pathol.
, vol.63
, pp. 289-295
-
-
Haines, G.K.1
Ghadge, G.D.2
Becker, S.3
Kies, M.4
Pelzer, H.5
Thimmapaya, B.6
Radosevich, J.A.7
-
27
-
-
0031456383
-
Elevated apoptotic cell population in patients with chronic fatigue syndrome: The pivotal role of protein kinase RNA
-
A. Vojdani, M. Ghoneum, P.C. Choppa, L. Magtoto, C.W. Lapp, Elevated apoptotic cell population in patients with chronic fatigue syndrome: the pivotal role of protein kinase RNA, J. Intern. Med. 242 (1997) 465-478.
-
(1997)
J. Intern. Med.
, vol.242
, pp. 465-478
-
-
Vojdani, A.1
Ghoneum, M.2
Choppa, P.C.3
Magtoto, L.4
Lapp, C.W.5
-
28
-
-
0029134011
-
Expression of p68 (PKR) in human colon cancer
-
C. Singh, G.K. Haines, M.S. Talamonti, J.A. Radosevich, Expression of p68 (PKR) in human colon cancer, Tumor Biol. 16 (1995) 281-289.
-
(1995)
Tumor Biol.
, vol.16
, pp. 281-289
-
-
Singh, C.1
Haines, G.K.2
Talamonti, M.S.3
Radosevich, J.A.4
-
29
-
-
0031458299
-
Interferon-responsive protein kinase (p68) and proliferating cell nuclear antigen are inversely distributed in head and neck squamous cell carcinoma
-
G.K. Haines, R.J. Panos, P.M. Bak, T. Brown, M. Zielinski, J. Leyland, J.A. Radosevich, Interferon-responsive protein kinase (p68) and proliferating cell nuclear antigen are inversely distributed in head and neck squamous cell carcinoma, Tumor Biol. 19 (1998) 52-59.
-
(1998)
Tumor Biol.
, vol.19
, pp. 52-59
-
-
Haines, G.K.1
Panos, R.J.2
Bak, P.M.3
Brown, T.4
Zielinski, M.5
Leyland, J.6
Radosevich, J.A.7
-
30
-
-
0029655361
-
Expression of p68 (PKR) in human breast tissues
-
G.K. Haines, R. Cajulis, R. Hayden, R. Duda, M. Talamonti, J.A. Radosevich, Expression of p68 (PKR) in human breast tissues, Tumor Biol. 17 (1996) 5-12.
-
(1996)
Tumor Biol.
, vol.17
, pp. 5-12
-
-
Haines, G.K.1
Cajulis, R.2
Hayden, R.3
Duda, R.4
Talamonti, M.5
Radosevich, J.A.6
-
31
-
-
0025129726
-
Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
-
H.D. Soule, T.M. Maloney, S.R. Wolman, W.D. Peterson, R. Brenz, C.M. McGrath, J. Russo, R.J. Pauley, R.F. Jones, S.C. Brooks, Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10, Cancer Res. 50 (1990) 6075-6086.
-
(1990)
Cancer Res.
, vol.50
, pp. 6075-6086
-
-
Soule, H.D.1
Maloney, T.M.2
Wolman, S.R.3
Peterson, W.D.4
Brenz, R.5
McGrath, C.M.6
Russo, J.7
Pauley, R.J.8
Jones, R.F.9
Brooks, S.C.10
-
32
-
-
0021275744
-
Further characterization of the protein kinase activity mediated by interferon in mouse and human cells
-
B. Krust, J. Galabru, A.G. Hovanessian, Further characterization of the protein kinase activity mediated by interferon in mouse and human cells, J. Biol. Chem. 259 (1984) 8494-8498.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 8494-8498
-
-
Krust, B.1
Galabru, J.2
Hovanessian, A.G.3
-
33
-
-
0023665208
-
Phosphorylation of eIF-2 during physiological stresses which affect protein synthesis
-
K.A. Scorsone, R. Panniers, A.G. Rowlands, E.C. Henshaw, Phosphorylation of eIF-2 during physiological stresses which affect protein synthesis, J. Biol. Chem. 262 (1987) 14538-14543.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 14538-14543
-
-
Scorsone, K.A.1
Panniers, R.2
Rowlands, A.G.3
Henshaw, E.C.4
-
34
-
-
0023708282
-
Influenza virus regulates protein synthesis by repressing the autophosphorylation of PKR
-
M.G. Katze, J. Tomita, T. Black, B. Safer, A.G. Hovanessian, Influenza virus regulates protein synthesis by repressing the autophosphorylation of PKR, J. Virol. 62 (1988) 3710-3717.
-
(1988)
J. Virol.
, vol.62
, pp. 3710-3717
-
-
Katze, M.G.1
Tomita, J.2
Black, T.3
Safer, B.4
Hovanessian, A.G.5
-
35
-
-
0027163011
-
Recombinant vaccinia virus K3L gene product prevents activation of double-stranded RNA-dependent initiation factor 2 alpha-specific protein kinase
-
K. Carroll, O. Elroy-Stein, B. Moss, R. Jagus, Recombinant vaccinia virus K3L gene product prevents activation of double-stranded RNA-dependent initiation factor 2 alpha-specific protein kinase, J. Biol. Chem. 268 (1993) 12837-12842.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 12837-12842
-
-
Carroll, K.1
Elroy-Stein, O.2
Moss, B.3
Jagus, R.4
-
36
-
-
0024593159
-
Cellular PKR is highly phosphorylated and activated yet significantly degraded during polio virus infection
-
T.L. Black, B. Safer, A.G. Hovanessian, M.G. Katze, Cellular PKR is highly phosphorylated and activated yet significantly degraded during polio virus infection, J. Virol. 63 (1989) 2244-2251.
-
(1989)
J. Virol.
, vol.63
, pp. 2244-2251
-
-
Black, T.L.1
Safer, B.2
Hovanessian, A.G.3
Katze, M.G.4
-
37
-
-
0344333720
-
Purification of eIF-2:eIF-2B complex and its nucleotide exchange activity
-
A. Konieczny, B. Safer, Purification of eIF-2:eIF-2B complex and its nucleotide exchange activity, J. Biol. Chem. 258 (1982) 3402-3408.
-
(1982)
J. Biol. Chem.
, vol.258
, pp. 3402-3408
-
-
Konieczny, A.1
Safer, B.2
-
38
-
-
0031009311
-
Use of vertical slab gel isoelectric focusing and immunoblotting to evaluate steady state levels of eIF2α phosphorylation in cells
-
O. Savinova, R. Jagus, Use of vertical slab gel isoelectric focusing and immunoblotting to evaluate steady state levels of eIF2α phosphorylation in cells, Methods 11 (1997) 419-425.
-
(1997)
Methods
, vol.11
, pp. 419-425
-
-
Savinova, O.1
Jagus, R.2
-
39
-
-
0029070762
-
Elevated levels of eIF4E mRNa in a broad spectrum of transformed cell lines
-
Y. Miyagi, A. Sugiyama, A. Asai, T. Okazaki, Y. Kuchino, S.J. Kerr, Elevated levels of eIF4E mRNA in a broad spectrum of transformed cell lines, Cancer Lett. 91 (1995) 247-252.
-
(1995)
Cancer Lett.
, vol.91
, pp. 247-252
-
-
Miyagi, Y.1
Sugiyama, A.2
Asai, A.3
Okazaki, T.4
Kuchino, Y.5
Kerr, S.J.6
-
40
-
-
0027289462
-
Increased expression of eukaryotic initiation factors eIF-4E and eIF-2α in response to growth induction by c-myc
-
I.B. Rosenwald, D.B. Rhoads, L.D. Callanan, K.J. Isselbacher, E.V. Schmidt, Increased expression of eukaryotic initiation factors eIF-4E and eIF-2α in response to growth induction by c-myc, Proc. Natl. Acad. Sci. 90 (1993) 6175-6178.
-
(1993)
Proc. Natl. Acad. Sci.
, vol.90
, pp. 6175-6178
-
-
Rosenwald, I.B.1
Rhoads, D.B.2
Callanan, L.D.3
Isselbacher, K.J.4
Schmidt, E.V.5
-
41
-
-
0030111237
-
Deregulation of protein synthesis as a mechanism of neoplastic transformation
-
I.B. Rosenwald, Deregulation of protein synthesis as a mechanism of neoplastic transformation, BioEssays 18 (1996) 243-250.
-
(1996)
BioEssays
, vol.18
, pp. 243-250
-
-
Rosenwald, I.B.1
-
42
-
-
0029873363
-
Upregulated expression of the genes encoding eIF4E and eIF2α in transformed cells
-
I.B. Rosenwald, Upregulated expression of the genes encoding eIF4E and eIF2α in transformed cells, Cancer Lett. 102 (1996) 113-123.
-
(1996)
Cancer Lett.
, vol.102
, pp. 113-123
-
-
Rosenwald, I.B.1
-
43
-
-
0344074151
-
Expression of a translationally regulated, dominant-negative C/EBPβ isoform and upregulation of eIF2α are correlated with neoplastic transformation of mammary epithelial cells
-
B. Raught, A.-C. Gingras, A. James, D. Medina, N. Sonenberg, J.M. Rosen, Expression of a translationally regulated, dominant-negative C/EBPβ isoform and upregulation of eIF2α are correlated with neoplastic transformation of mammary epithelial cells, Cancer Lett. 59 (1996) 4382-4386.
-
(1996)
Cancer Lett.
, vol.59
, pp. 4382-4386
-
-
Raught, B.1
Gingras, A.-C.2
James, A.3
Medina, D.4
Sonenberg, N.5
Rosen, J.M.6
-
44
-
-
0027399614
-
C-myc oncogene expression in estrogen-dependent and -independent breast cancer
-
R.P. Shiu, P.H. Watson, D. Dubik, c-myc oncogene expression in estrogen-dependent and -independent breast cancer, Clin. Chem. 39 (1993) 353-355.
-
(1993)
Clin. Chem.
, vol.39
, pp. 353-355
-
-
Shiu, R.P.1
Watson, P.H.2
Dubik, D.3
-
45
-
-
0028305728
-
A key transcription factor for eIF2α is strongly homologous to developmental transcription factors and may link metabolic genes to cellular growth and development
-
B.J. Efiok, J.A. Chiorini, B. Safer, A key transcription factor for eIF2α is strongly homologous to developmental transcription factors and may link metabolic genes to cellular growth and development, J. Biol. Chem. 269 (1994) 18921-18930.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18921-18930
-
-
Efiok, B.J.1
Chiorini, J.A.2
Safer, B.3
-
46
-
-
0029043142
-
Nuclear localization of PKR in human cells and transfected mouse cells
-
I.W. Jeffrey, S. Kadereit, T. Metzger, M. Bachmann, M. Scwemmle, A.G. Hovanessian, M.J. Clemens, Nuclear localization of PKR in human cells and transfected mouse cells, Exp. Cell Res. 218 (1995) 17-27.
-
(1995)
Exp. Cell Res.
, vol.218
, pp. 17-27
-
-
Jeffrey, I.W.1
Kadereit, S.2
Metzger, T.3
Bachmann, M.4
Scwemmle, M.5
Hovanessian, A.G.6
Clemens, M.J.7
-
47
-
-
0029996794
-
SV40 large-T antigen bypasses the translational block imposed by the phosphorylation of eIF2α
-
S. Swaminathan, P. Rajan, O. Savinova, R. Jagus, B. Thimmapaya, SV40 large-T antigen bypasses the translational block imposed by the phosphorylation of eIF2α, Virology 219 (1996) 321-323.
-
(1996)
Virology
, vol.219
, pp. 321-323
-
-
Swaminathan, S.1
Rajan, P.2
Savinova, O.3
Jagus, R.4
Thimmapaya, B.5
-
48
-
-
0028820772
-
The interferon-inducible protein kinase, PKR, mediates the transcriptional activation of the immunoglobulin κ gene
-
A. Koromilas, C. Cantin, A. Craig, R. Jagus, J. Hiscott, N. Sonenberg, The interferon-inducible protein kinase, PKR, mediates the transcriptional activation of the immunoglobulin κ gene, J. Biol. Chem. 270 (1995) 25426-25434.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25426-25434
-
-
Koromilas, A.1
Cantin, C.2
Craig, A.3
Jagus, R.4
Hiscott, J.5
Sonenberg, N.6
-
49
-
-
0028977912
-
Activation of PKR and induction of vascular cell adhesion molecule-1 by dsRNA in endothelial cells
-
M.K. Offerman, J. Zimring, K.H. Mellits, M.K. Hagan, R. Shaw, R.M. Medford, M.B. Mathews, S. Goodbourn, R. Jagus, Activation of PKR and induction of vascular cell adhesion molecule-1 by dsRNA in endothelial cells, Eur. J. Biochem. 232 (1995) 28-36.
-
(1995)
Eur. J. Biochem.
, vol.232
, pp. 28-36
-
-
Offerman, M.K.1
Zimring, J.2
Mellits, K.H.3
Hagan, M.K.4
Shaw, R.5
Medford, R.M.6
Mathews, M.B.7
Goodbourn, S.8
Jagus, R.9
-
50
-
-
17544376424
-
Modulations of IFN-inducible gene expression by retinoic acid: Upregulation of STAT1 in IFN-unresponsive cells
-
V. Kolla, D.J. Lindner, W. Xiao, E.C. Borden, D.V. Kalvakolanu, Modulations of IFN-inducible gene expression by retinoic acid: upregulation of STAT1 in IFN-unresponsive cells, J. Biol. Chem. 271 (1996) 10508-10514.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10508-10514
-
-
Kolla, V.1
Lindner, D.J.2
Xiao, W.3
Borden, E.C.4
Kalvakolanu, D.V.5
-
51
-
-
0023696578
-
A heat-sensitive inhibitor in poliovirus-infected cells which selectively blocks phosphorylation of eIF-2α by PKR
-
L.J. Ransome, A. Dasgupta, A heat-sensitive inhibitor in poliovirus-infected cells which selectively blocks phosphorylation of eIF-2α by PKR, J. Virol. 62 (1988) 3551-3557.
-
(1988)
J. Virol.
, vol.62
, pp. 3551-3557
-
-
Ransome, L.J.1
Dasgupta, A.2
-
52
-
-
0025298202
-
Molecular cloning and characterization of the double-stranded, RNA-activated protein kinase induced by interferon
-
E. Meurs, K. Chong, J. Galabru, N.S. Thomas, I.M. Kerr, B.R.G. Williams, A.G. Hovanessian, Molecular cloning and characterization of the double-stranded, RNA-activated protein kinase induced by interferon, Cell 62 (1990) 379-390
-
(1990)
Cell
, vol.62
, pp. 379-390
-
-
Meurs, E.1
Chong, K.2
Galabru, J.3
Thomas, N.S.4
Kerr, I.M.5
Williams, B.R.G.6
Hovanessian, A.G.7
-
53
-
-
0024078349
-
Effects of mutations in stem and loop regions on the structure and function of adenovirus VA RNA
-
K. Mellits, M.B. Mathews, Effects of mutations in stem and loop regions on the structure and function of adenovirus VA RNA, EMBO J. 7 (1988) 2849-2859.
-
(1988)
EMBO J.
, vol.7
, pp. 2849-2859
-
-
Mellits, K.1
Mathews, M.B.2
-
54
-
-
0025746604
-
Functional expression and characterization of interferon-induced double-stranded RNA activated P68 protein kinase from Escherichia coli
-
G.N. Barber, T. Tomita, A.G. Hovanessian, E. Meurs, M.G. Katze, Functional expression and characterization of interferon-induced double-stranded RNA activated P68 protein kinase from Escherichia coli, Biochem. 30 (1991) 10356-10361.
-
(1991)
Biochem.
, vol.30
, pp. 10356-10361
-
-
Barber, G.N.1
Tomita, T.2
Hovanessian, A.G.3
Meurs, E.4
Katze, M.G.5
-
55
-
-
0025361887
-
Interaction of adenovirus VAI RNA with PKR: Nonequivalence of binding and function
-
K.H. Mellits, M. Kostura, M.B. Mathews, Interaction of adenovirus VAI RNA with PKR: nonequivalence of binding and function, Cell 61 (1990) 843-852.
-
(1990)
Cell
, vol.61
, pp. 843-852
-
-
Mellits, K.H.1
Kostura, M.2
Mathews, M.B.3
-
56
-
-
0027487288
-
Comparative analysis of the regulation of PKR by Epstein-Barr virus RNAs, EBER-1 and EBER-2 and adenovirus VA1 RNA
-
T.V. Sharp, Q. Xiao, D.R. Gewert, M.J. Clemens, Comparative analysis of the regulation of PKR by Epstein-Barr virus RNAs, EBER-1 and EBER-2 and adenovirus VA1 RNA, Nucleic Acids Res. 21 (1993) 4483-4489.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 4483-4489
-
-
Sharp, T.V.1
Xiao, Q.2
Gewert, D.R.3
Clemens, M.J.4
-
57
-
-
0026511984
-
Role of the apical stem in maintaining structure and function of adenovirus-associated RNAs
-
K.H. Mellits, T. Pe'ery, M.B. Mathews, Role of the apical stem in maintaining structure and function of adenovirus-associated RNAs, J. Virol. 66 (1992) 2369-2377.
-
(1992)
J. Virol.
, vol.66
, pp. 2369-2377
-
-
Mellits, K.H.1
PE'Ery, T.2
Mathews, M.B.3
-
58
-
-
0000335423
-
Games viruses play: A strategic initiative against PKR
-
M.G. Katze, Games viruses play: a strategic initiative against PKR, Seminars Virol. 4 (1993) 259-268.
-
(1993)
Seminars Virol.
, vol.4
, pp. 259-268
-
-
Katze, M.G.1
-
59
-
-
0028589116
-
Proteins that interact with PKR
-
R. Jagus, M.E. Gray, Proteins that interact with PKR, Biochimie 76 (1994) 779-791.
-
(1994)
Biochimie
, vol.76
, pp. 779-791
-
-
Jagus, R.1
Gray, M.E.2
-
60
-
-
0030585155
-
When two strands are better than one: The mediators and modulators of the cellular responses to double-stranded RNA
-
B.L. Jacobs, J.O. Langland, When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA, Virology 219 (1996) 339-349.
-
(1996)
Virology
, vol.219
, pp. 339-349
-
-
Jacobs, B.L.1
Langland, J.O.2
-
61
-
-
0025180598
-
Purification and partial characterization of an inhibitor of PKR during influenza virus infection
-
T.G. Lee, J. Tomita, A.G. Hovanessian, M.G. Katze, Purification and partial characterization of an inhibitor of PKR during influenza virus infection, Proc. Natl. Acad. Sci. 87 (1990) 6208-6212.
-
(1990)
Proc. Natl. Acad. Sci.
, vol.87
, pp. 6208-6212
-
-
Lee, T.G.1
Tomita, J.2
Hovanessian, A.G.3
Katze, M.G.4
-
62
-
-
0026628369
-
Characterization and regulation of the 58 kDa cellular inhibitor of PKR
-
T.G. Lee, J. Tomita, A.G. Hovanessian, M.G. Katze, Characterization and regulation of the 58 kDa cellular inhibitor of PKR, J. Biol. Chem. 267 (1992) 14238-14243.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 14238-14243
-
-
Lee, T.G.1
Tomita, J.2
Hovanessian, A.G.3
Katze, M.G.4
-
64
-
-
0027949937
-
The 58-kDa cellular inhibitor of PKR is a member of the TPR family of proteins
-
T.G. Lee, N. Tang, S. Thompson, J. Miller, M.G. Katze, The 58-kDa cellular inhibitor of PKR is a member of the TPR family of proteins, Mol. Cell. Biol. 14 (1994) 2331-2342.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2331-2342
-
-
Lee, T.G.1
Tang, N.2
Thompson, S.3
Miller, J.4
Katze, M.G.5
-
65
-
-
8944219769
-
Interaction of the interferon-induced kinase, PKR, with inhibitory proteins p58 and vaccinia virus K3L is mediated by unique domains -implications for kinase function
-
M. Gale, S.L. Tan, M. Wambach, M.G. Katze, Interaction of the interferon-induced kinase, PKR, with inhibitory proteins p58 and vaccinia virus K3L is mediated by unique domains -implications for kinase function, Mol. Cell. Biol. 16 (1996) 4172-4181.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4172-4181
-
-
Gale, M.1
Tan, S.L.2
Wambach, M.3
Katze, M.G.4
-
66
-
-
0031013877
-
The molecular chaperone hsp40 regulates the activity of p58, the cellular inhibitor of PKR
-
M.W. Melville, W.J. Hansen, B.C. Freeman, W.J. Welch, M.G. Katze, The molecular chaperone hsp40 regulates the activity of p58, the cellular inhibitor of PKR, Proc. Natl. Acad. Sci. 94 (1997) 97-102.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 97-102
-
-
Melville, M.W.1
Hansen, W.J.2
Freeman, B.C.3
Welch, W.J.4
Katze, M.G.5
-
67
-
-
2642648639
-
Regulation of interferon-induced protein kinase PKR: Modulation of P58IPK inhibitory function by a novel protein, P52rIPK
-
M. Gale, C.M. Blakely, D.A. Hopkins, M.W. Melville, M. Wambach, P.R. Romano, M.G. Katze, Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPK, Mol. Cell. Biol. 18 (1998) 859-871.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 859-871
-
-
Gale, M.1
Blakely, C.M.2
Hopkins, D.A.3
Melville, M.W.4
Wambach, M.5
Romano, P.R.6
Katze, M.G.7
-
68
-
-
0026575232
-
The eIF2-associated 67-kDa polypeptide (p67) plays a critical role in the regulation of protein synthesis in animal cells
-
M.K. Ray, B. Datta, A. Chakraborty, A. Chattopadhyay, S. Meza-Keuthen, N.K. Gupta, The eIF2-associated 67-kDa polypeptide (p67) plays a critical role in the regulation of protein synthesis in animal cells, Proc. Natl. Acad. Sci. 89 (1992) 539-543.
-
(1992)
Proc. Natl. Acad. Sci.
, vol.89
, pp. 539-543
-
-
Ray, M.K.1
Datta, B.2
Chakraborty, A.3
Chattopadhyay, A.4
Meza-Keuthen, S.5
Gupta, N.K.6
-
69
-
-
0025819309
-
Partial characterization of a cellular factor that regulates dsRNA-dependent eIF-2α kinase in 3T3-F442a fibroblasts
-
R. Judware, R. Petryshyn, Partial characterization of a cellular factor that regulates dsRNA-dependent eIF-2α kinase in 3T3-F442A fibroblasts, Mol. Cell. Biol. 11 (1991) 3259-3267.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 3259-3267
-
-
Judware, R.1
Petryshyn, R.2
-
70
-
-
0026787750
-
Mechanism of action of a cellular inhibitor of the dsRNA-dependent protein kinase from 3T3-F442a cells
-
R. Judware, R. Petryshyn, Mechanism of action of a cellular inhibitor of the dsRNA-dependent protein kinase from 3T3-F442A cells, J. Biol. Chem. 267 (1992) 21685-21690.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 21685-21690
-
-
Judware, R.1
Petryshyn, R.2
-
71
-
-
0026343517
-
Inhibitor of interferon-induced dsRNA-dependent protein kinase
-
S. Saito, M. Kawakita, Inhibitor of interferon-induced dsRNA-dependent protein kinase, Microbiol. Immunol. 35 (1991) 1105-1114.
-
(1991)
Microbiol. Immunol.
, vol.35
, pp. 1105-1114
-
-
Saito, S.1
Kawakita, M.2
-
72
-
-
0025223478
-
Enhancement of the interferon-induced dsRNA-dependent protein kinase by Sindbis virus infection and heat-shock stress
-
S. Saito, Enhancement of the interferon-induced dsRNA-dependent protein kinase by Sindbis virus infection and heat-shock stress, Microbiol. Immunol. 34 (1990) 859-870.
-
(1990)
Microbiol. Immunol.
, vol.34
, pp. 859-870
-
-
Saito, S.1
-
73
-
-
0026481080
-
Oncogenic ras induces inhibition of PKR
-
L.J. Mundschau, D.V. Faller, Oncogenic ras induces inhibition of PKR, J. Biol. Chem. 267 (1992) 23092-23098.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 23092-23098
-
-
Mundschau, L.J.1
Faller, D.V.2
-
74
-
-
0028558943
-
Endogenous inhibitors of PKR in normal and ras transformed cells
-
L.J. Mundschau, D.V. Faller, Endogenous inhibitors of PKR in normal and ras transformed cells, Biochimie 76 (1994) 792-800.
-
(1994)
Biochimie
, vol.76
, pp. 792-800
-
-
Mundschau, L.J.1
Faller, D.V.2
-
75
-
-
0027966119
-
IL-3 stimulates protein synthesis by regulating dsRNA-dependent protein kinase (PKR)
-
T. Ito, R. Jagus, S. May, IL-3 stimulates protein synthesis by regulating dsRNA-dependent protein kinase (PKR), Proc. Natl. Acad. Sci. 91 (1994) 7455-7459.
-
(1994)
Proc. Natl. Acad. Sci.
, vol.91
, pp. 7455-7459
-
-
Ito, T.1
Jagus, R.2
May, S.3
-
76
-
-
0029670477
-
Translational control of p27Kip1 accumulation during the cell cycle
-
L. Hengst, S.I. Reed, Translational control of p27Kip1 accumulation during the cell cycle, Science 271 (1996) 1861-1864.
-
(1996)
Science
, vol.271
, pp. 1861-1864
-
-
Hengst, L.1
Reed, S.I.2
-
77
-
-
15144357686
-
Enhanced ribosomal association of p27(Kip1) mRNa is a mechanism contributing to accumulation during growth arrest
-
S.S. Millard, J.S. Yan, H. Nguyen, M. Pagano, H. Kiyokawa, A. Koff, Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest, J. Biol. Chem. 272 (1997) 7093-7098.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7093-7098
-
-
Millard, S.S.1
Yan, J.S.2
Nguyen, H.3
Pagano, M.4
Kiyokawa, H.5
Koff, A.6
-
78
-
-
0026698263
-
Association of human cyclin e with a periodic G1-S phase protein kinase
-
V. Dulic, S. Lee, S. Reed, Association of human cyclin E with a periodic G1-S phase protein kinase, Science 257 (1992) 1958-1961.
-
(1992)
Science
, vol.257
, pp. 1958-1961
-
-
Dulic, V.1
Lee, S.2
Reed, S.3
-
79
-
-
0028988585
-
Inhibitors of mammalian G1 cyclin-dependent kinases
-
C.J. Sherr, J.M. Roberts, Inhibitors of mammalian G1 cyclin-dependent kinases, Genes Dev. 9 (1995) 1149-1163.
-
(1995)
Genes Dev.
, vol.9
, pp. 1149-1163
-
-
Sherr, C.J.1
Roberts, J.M.2
-
80
-
-
16944363001
-
Decreased levels of the cell cycle inhibitor p27: Prognostic implications in primary breast cancer
-
C. Catzavelos, N. Bhattacharya, Y.C. Ung, J.A. Wilson, L. Roncari, C. Sandhu, P. Shaw, H. Yeger, I. Morava-Protzner, L. Kaputsa, E. Franssen, K.I. Pritchard, J.M. Slingerland, Decreased levels of the cell cycle inhibitor p27: prognostic implications in primary breast cancer, Nature Med. 3 (1997) 227-230.
-
(1997)
Nature Med.
, vol.3
, pp. 227-230
-
-
Catzavelos, C.1
Bhattacharya, N.2
Ung, Y.C.3
Wilson, J.A.4
Roncari, L.5
Sandhu, C.6
Shaw, P.7
Yeger, H.8
Morava-Protzner, I.9
Kaputsa, L.10
Franssen, E.11
Pritchard, K.I.12
Slingerland, J.M.13
-
81
-
-
0031048716
-
Expression of cell cycle regulators p27 and cyclin E, alone or in combination, correlate with survival in young breast cancer patients
-
P.L. Porter, K.E. Malone, P.J. Heagerty, G. M. Alexander, L.A. Gatti, E.J. Firpo, J.R. Daling, J.M. Roberts, Expression of cell cycle regulators p27 and cyclin E, alone or in combination, correlate with survival in young breast cancer patients, Nature Med. 3 (1997) 222-225.
-
(1997)
Nature Med.
, vol.3
, pp. 222-225
-
-
Porter, P.L.1
Malone, K.E.2
Heagerty, P.J.3
Alexander, G.M.4
Gatti, L.A.5
Firpo, E.J.6
Daling, J.R.7
Roberts, J.M.8
-
82
-
-
0031283125
-
Overexpression of C/EBPbeta-LIP, a naturally occurring, dominant-negative transcription factor, in human breast cancer
-
C.A. Zahnow, P. Younes, R. Laucirica, J.M. Rosen, Overexpression of C/EBPbeta-LIP, a naturally occurring, dominant-negative transcription factor, in human breast cancer, J. Natl. Cancer Inst. 89 (1997) 1887-1891
-
(1997)
J. Natl. Cancer Inst.
, vol.89
, pp. 1887-1891
-
-
Zahnow, C.A.1
Younes, P.2
Laucirica, R.3
Rosen, J.M.4
-
83
-
-
0031283125
-
Overexpression of C/EBPbeta-LIP, a naturally occurring, dominant-negative transcription factor, in human breast cancer
-
C.A. Zahnow, P. Younes, R. Laucirica, J.M. Rosen, Overexpression of C/EBPbeta-LIP, a naturally occurring, dominant-negative transcription factor, in human breast cancer, J. Natl. Cancer Inst. 89 (1997) 1887-1891.
-
(1997)
J. Natl. Cancer Inst.
, vol.89
, pp. 1887-1891
-
-
Zahnow, C.A.1
Younes, P.2
Laucirica, R.3
Rosen, J.M.4
-
84
-
-
0028013216
-
LAP (NF-IL-6), a tissue-specific transcriptional activator, is an inhibitor of hepatoma cell proliferation
-
M. Buck, H. Turler, M. Chojkier, LAP (NF-IL-6), a tissue-specific transcriptional activator, is an inhibitor of hepatoma cell proliferation, EMBO J. 13 (1994) 851-860.
-
(1994)
EMBO J.
, vol.13
, pp. 851-860
-
-
Buck, M.1
Turler, H.2
Chojkier, M.3
-
85
-
-
0028944271
-
Expression of bcl-2 family in normal and malignant breast tissue
-
R.C. Bargou, P.T. Daniel, M.Y. Mapara, K. Bommert, C. Wagener, B. Kallinich, H.D. Royer, B. Dorken, Expression of bcl-2 family in normal and malignant breast tissue, Int. J. Cancer 60 (1995) 854-859.
-
(1995)
Int. J. Cancer
, vol.60
, pp. 854-859
-
-
Bargou, R.C.1
Daniel, P.T.2
Mapara, M.Y.3
Bommert, K.4
Wagener, C.5
Kallinich, B.6
Royer, H.D.7
Dorken, B.8
-
86
-
-
0029045784
-
Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma
-
S. Krajewski, C. Blomqvist, K. Franssila, M. Krajewska, V.M. Wasenius, E. Niskanen, S. Nordling, J.C. Reed, Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma, Cancer Res. 55 (1995) 4471-4478.
-
(1995)
Cancer Res.
, vol.55
, pp. 4471-4478
-
-
Krajewski, S.1
Blomqvist, C.2
Franssila, K.3
Krajewska, M.4
Wasenius, V.M.5
Niskanen, E.6
Nordling, S.7
Reed, J.C.8
-
87
-
-
0030803256
-
Translational regulation of yeast GCN4. a window on factors that control initiator-tRNa binding to the ribosome
-
A.G. Hinnebusch, Translational regulation of yeast GCN4. A window on factors that control initiator-tRNA binding to the ribosome, J. Biol. Chem. 272 (1997) 21661-21664.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21661-21664
-
-
Hinnebusch, A.G.1
-
88
-
-
0030162560
-
Balancing cell life and death: Bax, apoptosis and breast cancer
-
J.C. Reed, Balancing cell life and death: bax, apoptosis and breast cancer, J. Clin. Invest. 97 (1996) 2403-2404.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2403-2404
-
-
Reed, J.C.1
|