메뉴 건너뛰기




Volumn 8, Issue 6, 2005, Pages 757-775

Polymer-assisted solution-phase chemical library synthesis

Author keywords

Polymer assisted solution phase synthesis; Resin capture release; Tagged reagents substrates

Indexed keywords

ALANINE DERIVATIVE; ANTHRACENE; ANTICOAGULANT AGENT; BENZAZEPINE DERIVATIVE; BENZODIAZEPINE DERIVATIVE; BENZOIC ACID DERIVATIVE; BENZOTRIAZOLE DERIVATIVE; COLECALCIFEROL DERIVATIVE; CYANAMIDE; ETHYLENE GLYCOL; GLYCOSIDE; GUANIDINE; IMIDAZOLE DERIVATIVE; OXADIAZOLE DERIVATIVE; PHOSPHINE; PHOSPHORUS DERIVATIVE; POLYMER; PROTEINASE INHIBITOR; PYRAZOLE DERIVATIVE; THIAZINE DERIVATIVE; TRIFLUOROACETIC ACID;

EID: 27844536483     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (16)

References (36)
  • 1
    • 2442658813 scopus 로고    scopus 로고
    • 1,2,3,4-Tetrahydro-γ-carbolinium salts. Novel reactions with thiols, mediated by polymer-supported reagents
    • Lizarzaburu ME, Shuttleworth SJ: 1,2,3,4-Tetrahydro-γ-carbolinium salts. Novel reactions with thiols, mediated by polymer-supported reagents. Tetrahedron Lett (2004) 45(24):4781-4783.
    • (2004) Tetrahedron Lett , vol.45 , Issue.24 , pp. 4781-4783
    • Lizarzaburu, M.E.1    Shuttleworth, S.J.2
  • 3
    • 5144232199 scopus 로고    scopus 로고
    • Expedited SAR study of an mGluR5 antagonists: Generation of a focused library using a solution-phase Suzuki coupling methodology
    • Eastman B, Chen C, Smith ND, Poon S, Chung J, Reyes-Manalo G, Cosford ND, Munoz B: Expedited SAR study of an mGluR5 antagonists: Generation of a focused library using a solution-phase Suzuki coupling methodology. Bioorg Med Chem Lett (2004) 14(22):5485-5488.
    • (2004) Bioorg Med Chem Lett , vol.14 , Issue.22 , pp. 5485-5488
    • Eastman, B.1    Chen, C.2    Smith, N.D.3    Poon, S.4    Chung, J.5    Reyes-Manalo, G.6    Cosford, N.D.7    Munoz, B.8
  • 4
    • 1042288489 scopus 로고    scopus 로고
    • Combinatorial synthesis of functionalized 1,3-thiazine libraries using a combined polymer-supported reagent/catch-and-release strategy
    • Strohmeier GA, Kappe CO: Combinatorial synthesis of functionalized 1,3-thiazine libraries using a combined polymer-supported reagent/catch-and- release strategy. Angew Chem Int Ed (2004) 43(5):621-624.
    • (2004) Angew Chem Int Ed , vol.43 , Issue.5 , pp. 621-624
    • Strohmeier, G.A.1    Kappe, C.O.2
  • 5
    • 0942300606 scopus 로고    scopus 로고
    • Modular three-component solid-phase synthesis of unsymmetrical guanidines via resin capture of carbodiimides
    • Boguszewski PA, Rahman SS, Ganesan A: Modular three-component solid-phase synthesis of unsymmetrical guanidines via resin capture of carbodiimides. J Comb Chem (2004) 6(1):32-34.
    • (2004) J Comb Chem , vol.6 , Issue.1 , pp. 32-34
    • Boguszewski, P.A.1    Rahman, S.S.2    Ganesan, A.3
  • 7
    • 0036654301 scopus 로고    scopus 로고
    • New developments in chemical library synthesis. Norbornenyl tags for use in phase-switching, sequestration, capture-release and soluble support applications
    • Flynn DL, Hanson PR, Berk SC, Makara GM: New developments in chemical library synthesis. Norbornenyl tags for use in phase-switching, sequestration, capture-release and soluble support applications. Curr Opin Drug Discovery Dev (2002) 5(4):571-579.
    • (2002) Curr Opin Drug Discovery Dev , vol.5 , Issue.4 , pp. 571-579
    • Flynn, D.L.1    Hanson, P.R.2    Berk, S.C.3    Makara, G.M.4
  • 8
    • 0036811250 scopus 로고    scopus 로고
    • ROMPgel reagents in parallel synthesis
    • Barrett AG, Hopkins BT, Kobberling J: ROMPgel reagents in parallel synthesis. Chem Rev (2002) 102(10):3301-3323.
    • (2002) Chem Rev , vol.102 , Issue.10 , pp. 3301-3323
    • Barrett, A.G.1    Hopkins, B.T.2    Kobberling, J.3
  • 9
    • 0036663850 scopus 로고    scopus 로고
    • Fluorous techniques for combinatorial and parallel synthesis
    • Curran DP: Fluorous techniques for combinatorial and parallel synthesis. Pharma News (2002) 9(3):179-188.
    • (2002) Pharma News , vol.9 , Issue.3 , pp. 179-188
    • Curran, D.P.1
  • 10
    • 10444255354 scopus 로고    scopus 로고
    • Fluorous tagging strategy for solution-phase synthesis of small molecules, peptides and oligosaccharides
    • Zhang W: Fluorous tagging strategy for solution-phase synthesis of small molecules, peptides and oligosaccharides. Curr Opin Drug Discovery Dev (2004) 7(6):784-797.
    • (2004) Curr Opin Drug Discovery Dev , vol.7 , Issue.6 , pp. 784-797
    • Zhang, W.1
  • 11
    • 15444379608 scopus 로고    scopus 로고
    • TEMPO-derived task-specific ionic liquids for oxidation of alcohols
    • Wu XE, Ma L, Ding MX, Gao, Lian X: TEMPO-derived task-specific ionic liquids for oxidation of alcohols. Synlett (2005) (4):607-610.
    • (2005) Synlett , Issue.4 , pp. 607-610
    • Wu, X.E.1    Ma, L.2    Ding, M.X.3    Gao4    Lian, X.5
  • 12
    • 0347916940 scopus 로고    scopus 로고
    • Exploration of ionic liquids as soluble supports for organic synthesis. Demonstration with a Suzuki coupling reaction
    • Miao W, Chan TH: Exploration of ionic liquids as soluble supports for organic synthesis. Demonstration with a Suzuki coupling reaction. Org Lett (2003) 5(26):5003-5005.
    • (2003) Org Lett , vol.5 , Issue.26 , pp. 5003-5005
    • Miao, W.1    Chan, T.H.2
  • 13
    • 1242317869 scopus 로고    scopus 로고
    • Development of a novel ionic support and its application in the ionic liquid phase assisted synthesis of a potent antithrombotic
    • de Kort M, Tuin AW, Kuiper S, Overkleeft HS, van der Marel GA, Buijsman RC: Development of a novel ionic support and its application in the ionic liquid phase assisted synthesis of a potent antithrombotic. Tetrahedron Lett (2004) 45(10):2171-2175.
    • (2004) Tetrahedron Lett , vol.45 , Issue.10 , pp. 2171-2175
    • De Kort, M.1    Tuin, A.W.2    Kuiper, S.3    Overkleeft, H.S.4    Van Der Marel, G.A.5    Buijsman, R.C.6
  • 14
    • 3242701692 scopus 로고    scopus 로고
    • Precipiton reagents: Precipiton phosphines for solution-phase reductions
    • Bosanac T, Wilcox CS: Precipiton reagents: Precipiton phosphines for solution-phase reductions. Org Lett (2004) 6(14):2321-2324.
    • (2004) Org Lett , vol.6 , Issue.14 , pp. 2321-2324
    • Bosanac, T.1    Wilcox, C.S.2
  • 15
    • 4344579712 scopus 로고    scopus 로고
    • Preparation and evaluation of bipyridyl-tagged reagents and scavengers
    • Convers E, Tye H, Whittaker M: Preparation and evaluation of bipyridyl-tagged reagents and scavengers. Tetrahedron (2004) 60(39):8729-8738.
    • (2004) Tetrahedron , vol.60 , Issue.39 , pp. 8729-8738
    • Convers, E.1    Tye, H.2    Whittaker, M.3
  • 16
    • 13844272603 scopus 로고    scopus 로고
    • Dialyzable carbosilane dendrimers as soluble supports for the functionalization of pyridine fragments via palladium-catalyzed coupling reactions
    • Le Notre J, Firet JJ, Sliedregt LA, Van Steen BJ, Van Koten G, Klein Gebbink RJ: Dialyzable carbosilane dendrimers as soluble supports for the functionalization of pyridine fragments via palladium-catalyzed coupling reactions. Org Lett (2005) 7(3):363-366.
    • (2005) Org Lett , vol.7 , Issue.3 , pp. 363-366
    • Le Notre, J.1    Firet, J.J.2    Sliedregt, L.A.3    Van Steen, B.J.4    Van Koten, G.5    Klein Gebbink, R.J.6
  • 17
    • 13944275622 scopus 로고    scopus 로고
    • Oligomeric ethylene glycols as sorting tags for parallel and combinatorial mixture synthesis
    • Wilcox CS, Turkyilmaz S: Oligomeric ethylene glycols as sorting tags for parallel and combinatorial mixture synthesis. Tetrahedron Lett (2005) 46(11):1827-1829.
    • (2005) Tetrahedron Lett , vol.46 , Issue.11 , pp. 1827-1829
    • Wilcox, C.S.1    Turkyilmaz, S.2
  • 18
    • 0141572268 scopus 로고    scopus 로고
    • The development of a chromatography-free Mitsunobu reaction: Synthesis and applications of an anthracene-tagged phosphine reagent
    • Lan P, Porco JA Jr, South MS, Parlow JJ: The development of a chromatography-free Mitsunobu reaction: Synthesis and applications of an anthracene-tagged phosphine reagent. J Comb Chem (2003) 5(5):660-669.
    • (2003) J Comb Chem , vol.5 , Issue.5 , pp. 660-669
    • Lan, P.1    Porco Jr., J.A.2    South, M.S.3    Parlow, J.J.4
  • 19
    • 0344666674 scopus 로고    scopus 로고
    • Polymer-assisted solution-phase (PASP) Suzuki couplings employing an anthracene-tagged palladium catalyst
    • Lan P, Berta D, Porco JA, South MS, Parlow JJ: Polymer-assisted solution-phase (PASP) Suzuki couplings employing an anthracene-tagged palladium catalyst J Org Chem (2003) 68(25):9678-9686.
    • (2003) J Org Chem , vol.68 , Issue.25 , pp. 9678-9686
    • Lan, P.1    Berta, D.2    Porco, J.A.3    South, M.S.4    Parlow, J.J.5
  • 20
    • 0038441605 scopus 로고    scopus 로고
    • A novel anthracenyl tagged protecting group for "phase- switching" applications in parallel synthesis
    • Li X, Abell C, Ladlow M: A novel anthracenyl tagged protecting group for "phase-switching" applications In parallel synthesis. J Org Chem (2003) 68(11):4189-4194.
    • (2003) J Org Chem , vol.68 , Issue.11 , pp. 4189-4194
    • Li, X.1    Abell, C.2    Ladlow, M.3
  • 21
    • 2342580707 scopus 로고    scopus 로고
    • A novel phase-switching protecting group for multi-step parallel solution phase synthesis
    • Li X, Abell C, Congreve MS, Warrington BH, Ladlow M: A novel phase-switching protecting group for multi-step parallel solution phase synthesis. Org Biomol Chem (2004) 2(7):989-998.
    • (2004) Org Biomol Chem , vol.2 , Issue.7 , pp. 989-998
    • Li, X.1    Abell, C.2    Congreve, M.S.3    Warrington, B.H.4    Ladlow, M.5
  • 22
    • 18844454506 scopus 로고    scopus 로고
    • The rapid preparation of 2-aminosulfonamide-1,3,4-oxadiazoles using polymer-supported reagents and microwave heating
    • Baxendqale IR, Ley SV, Martinelli M: The rapid preparation of 2-aminosulfonamide-1,3,4-oxadiazoles using polymer-supported reagents and microwave heating. Tetrahedron (2005) 61(22):5323-5349.
    • (2005) Tetrahedron , vol.61 , Issue.22 , pp. 5323-5349
    • Baxendqale, I.R.1    Ley, S.V.2    Martinelli, M.3
  • 23
    • 2342488212 scopus 로고    scopus 로고
    • One-pot preparation and activation of glycosyl trichloroacetimidates: Operationally simple glycosylation induced by combined use of solid-supported, reactivity-opposing reagents
    • Oikawa M, Tanaka T, Fukuda N, Kusumoto S: One-pot preparation and activation of glycosyl trichloroacetimidates: Operationally simple glycosylation induced by combined use of solid-supported, reactivity-opposing reagents. Tetrahedron Lett (2004) 45(21):4039-4042.
    • (2004) Tetrahedron Lett , vol.45 , Issue.21 , pp. 4039-4042
    • Oikawa, M.1    Tanaka, T.2    Fukuda, N.3    Kusumoto, S.4
  • 24
    • 0141906323 scopus 로고    scopus 로고
    • Synthesis of carbohydrate derivatives using solid-phase work-up and scavenging techniques
    • MacCoss RN, Brennan PE, Ley SV: Synthesis of carbohydrate derivatives using solid-phase work-up and scavenging techniques. Org Biomol Chem (2003) 1(12):2029-2031.
    • (2003) Org Biomol Chem , vol.1 , Issue.12 , pp. 2029-2031
    • MacCoss, R.N.1    Brennan, P.E.2    Ley, S.V.3
  • 25
    • 2542589435 scopus 로고    scopus 로고
    • Fully automated polymer-assisted synthesis of 1,5-biaryl pyrazoles
    • Vickerstaffe E, Warrington BH, Ladlow M, Ley SV: Fully automated polymer-assisted synthesis of 1,5-biaryl pyrazoles. J Comb Chem (2004) 6(3):332-339.
    • (2004) J Comb Chem , vol.6 , Issue.3 , pp. 332-339
    • Vickerstaffe, E.1    Warrington, B.H.2    Ladlow, M.3    Ley, S.V.4
  • 26
    • 1242328670 scopus 로고    scopus 로고
    • Multicomponent Hantzsch cyclocondensation as a route to highly functionalized 2- And 4-dihydropyridylalanlnes, 2- and 4-pyridylalanines, and their N-oxides: Preparation via a polymer-assisted solution-phase approach
    • Dondoni A, Massi A, Minghini E, Bertolasi V: Multicomponent Hantzsch cyclocondensation as a route to highly functionalized 2- and 4-dihydropyridylalanlnes, 2- and 4-pyridylalanines, and their N-oxides: Preparation via a polymer-assisted solution-phase approach. Tetrahedron (2004) 60(10):2311-2326.
    • (2004) Tetrahedron , vol.60 , Issue.10 , pp. 2311-2326
    • Dondoni, A.1    Massi, A.2    Minghini, E.3    Bertolasi, V.4
  • 27
    • 2342640881 scopus 로고    scopus 로고
    • Automated parallel, multi-step polymer-assisted solution phase (PASP) synthesis of substituted benzimidazole derivatives
    • Andrews SP, Jonsson D, Warrington BH, Ladlow M: Automated parallel, multi-step polymer-assisted solution phase (PASP) synthesis of substituted benzimidazole derivatives. Comb Chem High Throughput Screen (2004) 7(2): 161-176.
    • (2004) Comb Chem High Throughput Screen , vol.7 , Issue.2 , pp. 161-176
    • Andrews, S.P.1    Jonsson, D.2    Warrington, B.H.3    Ladlow, M.4
  • 28
    • 4143050396 scopus 로고    scopus 로고
    • Automated flow-through synthesis of heterocyclic thioethers
    • Jonsson D, Warrington BH, Ladlow M: Automated flow-through synthesis of heterocyclic thioethers. J Comb Chem (2004) 6(4):584-595.
    • (2004) J Comb Chem , vol.6 , Issue.4 , pp. 584-595
    • Jonsson, D.1    Warrington, B.H.2    Ladlow, M.3
  • 29
    • 9644254197 scopus 로고    scopus 로고
    • Synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepines by employing polymer-supported reagents: Preparation of DC-81
    • Kamal A, Reddy KL, Devaiah V, Shankaraiah N: Synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepines by employing polymer-supported reagents: Preparation of DC-81. Synlett (2004) (14):2533-2536.
    • (2004) Synlett , Issue.14 , pp. 2533-2536
    • Kamal, A.1    Reddy, K.L.2    Devaiah, V.3    Shankaraiah, N.4
  • 30
    • 8744253299 scopus 로고    scopus 로고
    • Environmentally benign preparation of heteroaromatics from ketones or alcohols, with macroporous polystyrenesulfonic acid and (diacetoxyiodo)benzene, followed by thioamide, amidine and 2-aminopyridine
    • Ueno M, Togo H: Environmentally benign preparation of heteroaromatics from ketones or alcohols, with macroporous polystyrenesulfonic acid and (diacetoxyiodo)benzene, followed by thioamide, amidine and 2-aminopyridine. Synthesis (2004) (16):2673-2677.
    • (2004) Synthesis , Issue.16 , pp. 2673-2677
    • Ueno, M.1    Togo, H.2
  • 31
    • 4143076840 scopus 로고    scopus 로고
    • Solid-supported solution-phase synthesis of 4-amino-1,2,4,5-tetrahydro-2- benzazepine-3-ones
    • Van den Eynde I, Van Rompaey K, Lazzaro F, Tourwe O: Solid-supported solution-phase synthesis of 4-amino-1,2,4,5-tetrahydro-2-benzazepine-3-ones. J Comb Chem (2004) 6(4):468-473.
    • (2004) J Comb Chem , vol.6 , Issue.4 , pp. 468-473
    • Van Den Eynde, I.1    Van Rompaey, K.2    Lazzaro, F.3    Tourwe, O.4
  • 32
    • 2942604950 scopus 로고    scopus 로고
    • Multi-step application of immobilized reagents and scavengers: A total synthesis of epothilone C
    • Storer RI, Takemoto T, Jackson PS, Brown DS, Baxendale IR, Ley SV: Multi-step application of immobilized reagents and scavengers: A total synthesis of epothilone C. Chemistry (2004) 10(10):2529-2547.
    • (2004) Chemistry , vol.10 , Issue.10 , pp. 2529-2547
    • Storer, R.I.1    Takemoto, T.2    Jackson, P.S.3    Brown, D.S.4    Baxendale, I.R.5    Ley, S.V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.