Automated Parallel, Multi-Step Polymer-Assisted Solution Phase (PASP) Synthesis of Substituted Benzimidazole Derivatives

Combinatorial Chemistry and High Throughput Screening

Volumn 7, Issue 2, 2004, Pages 163-178

  Andrews, Stephen P ^a   Jönsson, Daniel ^a   Warrington, Brian H ^a   Ladlow, Mark ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Automation; Benzimidazole; Capture and Release; PASP; Polymer Assisted; Solution Phase

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; BENZIMIDAZOLIN 2 ONE; POLYMER; THIOBENZIMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; COMBINATORIAL LIBRARY; COMMERCIAL PHENOMENA; LABORATORY APPARATUS, EQUIPMENT AND SUPPLIES; LABORATORY AUTOMATION; PRIORITY JOURNAL; PURIFICATION; ROBOTICS; SYNTHESIS; AUTOMATION; CHEMISTRY; COMBINATORIAL CHEMISTRY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

AUTOMATION; BENZIMIDAZOLES; COMBINATORIAL CHEMISTRY TECHNIQUES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; POLYMERS;

EID: 2342640881     PISSN: 13862073     EISSN: None     Source Type: Journal    
DOI: 10.2174/138620704773120847     Document Type: Article

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24. MP-trisamine: (tris-(2-aminoethyl)aminomethyl poly(styrene-co-divinylbenzene)), product number 800397, was obtained from Argonaut Technologies (www.argotech.com).
25. PS-thiourea: methylthiourea polystyrene, product number 01-64-0181, was obtained from CN Biosciences (www.cnbiosciences.co.uk).
26. PS-HOBt(HL): 1-hydroxybenzotriazole-6-sulfonamidomethyl polystyrene, product number 800417, was obtained from Argonaut Technologies.