메뉴 건너뛰기




Volumn 107, Issue 3, 2005, Pages 231-245

Methylmercury alters the in vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells

Author keywords

GLAST; GLT 1; Glutamate transport; Methylmercury; Neurotoxicity

Indexed keywords

GLUTAMIC ACID; MESSENGER RNA; METHYLMERCURY;

EID: 27844497048     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1385/BTER:107:3:231     Document Type: Article
Times cited : (30)

References (45)
  • 1
    • 0015783264 scopus 로고
    • Methylmercury poisoning in Iraq
    • F. Bakir, S. F. Damluji, L. Amin-Zaki, et al., Methylmercury poisoning in Iraq. Science 181, 230-241 (1973).
    • (1973) Science , vol.181 , pp. 230-241
    • Bakir, F.1    Damluji, S.F.2    Amin-Zaki, L.3
  • 2
    • 0000413892 scopus 로고
    • Biological reactions and pathological changes in human beings and animals caused by organic mercury contamination
    • R. Hartung and B. D. Dinman, eds., Ann Arbor Science, Ann Arbor, MI
    • T. Takeuchi, Biological reactions and pathological changes in human beings and animals caused by organic mercury contamination, in Environmental Mercury Contamination, R. Hartung and B. D. Dinman, eds., Ann Arbor Science, Ann Arbor, MI, pp 247-289 (1972).
    • (1972) Environmental Mercury Contamination , pp. 247-289
    • Takeuchi, T.1
  • 3
    • 0029943154 scopus 로고    scopus 로고
    • Changes in the number of astrocytes and microglia in the thalamus of the monkey Macaca fascicularis following long-term subclinical methylmercury exposure
    • J. S. Charleston, R. L. Body, R. P. Bolander, et al., Changes in the number of astrocytes and microglia in the thalamus of the monkey Macaca fascicularis following long-term subclinical methylmercury exposure, Neurotoxicology 17, 127-138 (1996).
    • (1996) Neurotoxicology , vol.17 , pp. 127-138
    • Charleston, J.S.1    Body, R.L.2    Bolander, R.P.3
  • 4
    • 0028351420 scopus 로고
    • The role of -SH groups in methylmercuric chloride-induced D-aspartate and rubidium release from rat primary astrocyte cultures
    • K. J. Mullaney M. N. Fehm, D. Vitarella, et al., The role of -SH groups in methylmercuric chloride-induced D-aspartate and rubidium release from rat primary astrocyte cultures, Brain Res. 641, 1-9 (1994).
    • (1994) Brain Res. , vol.641 , pp. 1-9
    • Mullaney, K.J.1    Fehm, M.N.2    Vitarella, D.3
  • 5
    • 0035947014 scopus 로고    scopus 로고
    • 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase
    • 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase, Brain Res. 902, 92-100 (2001).
    • (2001) Brain Res. , vol.902 , pp. 92-100
    • Allen, J.W.1    Mutkus, L.A.2    Aschner, M.3
  • 6
    • 4344644501 scopus 로고    scopus 로고
    • Free radical formation in cerebral cortical astrocytes in culture induced by methylmercury
    • G. Shanker, J. L. Aschner, T. Syversen, et al., Free radical formation in cerebral cortical astrocytes in culture induced by methylmercury Mol. Brain Res. 128, 48-57 (2004).
    • (2004) Mol. Brain Res. , vol.128 , pp. 48-57
    • Shanker, G.1    Aschner, J.L.2    Syversen, T.3
  • 7
    • 20444403753 scopus 로고    scopus 로고
    • Modulatory effect of glutathione status and antioxidants on methylmercury induced free radical formation in primary cultures of cerebral astrocytes
    • G. Shanker, T. Syversen, J. L. Aschner, et al., Modulatory effect of glutathione status and antioxidants on methylmercury induced free radical formation in primary cultures of cerebral astrocytes, Brain Res. Mol. Brain Res. 137, 11-22 (2005).
    • (2005) Brain Res. Mol. Brain Res. , vol.137 , pp. 11-22
    • Shanker, G.1    Syversen, T.2    Aschner, J.L.3
  • 8
    • 0028060648 scopus 로고    scopus 로고
    • Localization of neuronal and glial glutamate transporters
    • J. D. Rothstein, L. Martin, A. I. Levey et al., Localization of neuronal and glial glutamate transporters, Neuron 13, 713-725 (1996).
    • (1996) Neuron , vol.13 , pp. 713-725
    • Rothstein, J.D.1    Martin, L.2    Levey, A.I.3
  • 9
    • 0026489330 scopus 로고
    • Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain
    • T. Storck, S. Schulte, K. Hofmann, et al., Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain, Proc. Natl. Acad. Sci. USA 89, 10,955-10,959 (1992).
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89
    • Storck, T.1    Schulte, S.2    Hofmann, K.3
  • 10
    • 0026486310 scopus 로고
    • Cloning and expression of a rat brain L-glutamate transporter
    • G. Pines, N. C. Danbolt, M. Bjoras, et al., Cloning and expression of a rat brain L-glutamate transporter, Nature 360, 464-467 (1992).
    • (1992) Nature , vol.360 , pp. 464-467
    • Pines, G.1    Danbolt, N.C.2    Bjoras, M.3
  • 11
    • 0026458124 scopus 로고
    • Primary structure and functional characterization of a high-affinity glutamate transporter
    • Y. Kanai and M. A. Hediger, Primary structure and functional characterization of a high-affinity glutamate transporter, Nature 360, 467-471 (1992).
    • (1992) Nature , vol.360 , pp. 467-471
    • Kanai, Y.1    Hediger, M.A.2
  • 12
    • 0032699070 scopus 로고    scopus 로고
    • Functional diversity of excitatory amino acid transporters: Ion channel and transport modes
    • W. A. Fairman and S. G. Amara, Functional diversity of excitatory amino acid transporters: ion channel and transport modes, Am. J. Physiol. 277, F481-F486 (1999).
    • (1999) Am. J. Physiol. , vol.277
    • Fairman, W.A.1    Amara, S.G.2
  • 13
    • 0030932152 scopus 로고    scopus 로고
    • Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance
    • J. L. Arriza, S. Eliasof, M. P. Kavanaugh, et al., Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance, Proc. Natl. Acad. Sci. USA 94, 4155-4160 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4155-4160
    • Arriza, J.L.1    Eliasof, S.2    Kavanaugh, M.P.3
  • 14
    • 0030858918 scopus 로고    scopus 로고
    • Family of neutral and acidic amino acid transporters: Molecular biology, physiology and medical implications
    • Y. Kanai, Family of neutral and acidic amino acid transporters: molecular biology, physiology and medical implications, Curr. Opin. Cell Biol. 9, 565-572 (1997).
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 565-572
    • Kanai, Y.1
  • 15
    • 0029910823 scopus 로고    scopus 로고
    • Brain glutamate transporter proteins from homomultimers
    • O. Haugeto, K. Ullensvang, L. M. Levy, et al., Brain glutamate transporter proteins from homomultimers, J. Biol. Chem. 271, 27,715-27,722 (1996).
    • (1996) J. Biol. Chem. , vol.271
    • Haugeto, O.1    Ullensvang, K.2    Levy, L.M.3
  • 16
    • 0025316950 scopus 로고
    • Purification and reconstitution of the sodium-and potassium-coupled glutamate transport glycoprotein from rat brain
    • N. C. Danbolt, G. Pines, and B. I. Kanner, Purification and reconstitution of the sodium-and potassium-coupled glutamate transport glycoprotein from rat brain, Biochemistry 29, 6734-6740 (1990).
    • (1990) Biochemistry , vol.29 , pp. 6734-6740
    • Danbolt, N.C.1    Pines, G.2    Kanner, B.I.3
  • 17
    • 0032862658 scopus 로고    scopus 로고
    • Expression patterns and regulation of glutamate transporters in the developing and adult nervous system
    • K. D. Sims and M. B. Robinson, Expression patterns and regulation of glutamate transporters in the developing and adult nervous system, Crit. Rev. Neurobiol. 13, 169-197 (1999).
    • (1999) Crit. Rev. Neurobiol. , vol.13 , pp. 169-197
    • Sims, K.D.1    Robinson, M.B.2
  • 18
    • 0028958939 scopus 로고
    • Differential expression of two glial glutamate transporters in the rat brain: Quantitative and immunocytochemical observations
    • K. P. Lehre, L. M. Levy, O. P. Ottersen, et al., Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations, J. Neurosci. 15, 1835-1853 (1995).
    • (1995) J. Neurosci. , vol.15 , pp. 1835-1853
    • Lehre, K.P.1    Levy, L.M.2    Ottersen, O.P.3
  • 19
    • 0028904229 scopus 로고
    • Reduced postischemic expression of a glial glutamate transporter, GLT1 in the rat hippocampus
    • R. Torp, D. Lekieffre, L. M. Levy, et al., Reduced postischemic expression of a glial glutamate transporter, GLT1 in the rat hippocampus, Exp. Brain Res. 103, 51-58 (1995).
    • (1995) Exp. Brain Res. , vol.103 , pp. 51-58
    • Torp, R.1    Lekieffre, D.2    Levy, L.M.3
  • 20
    • 0034257045 scopus 로고    scopus 로고
    • Are neuronal transporters relevant in retinal glutamate homeostasis?
    • D. V. Pow, N. L. Barnett, and P. Penfold, Are neuronal transporters relevant in retinal glutamate homeostasis? Neurochem. Int. 37, 191-198 (2000).
    • (2000) Neurochem. Int. , vol.37 , pp. 191-198
    • Pow, D.V.1    Barnett, N.L.2    Penfold, P.3
  • 21
    • 0031879593 scopus 로고    scopus 로고
    • The expression of the glial glutamate transporter protein EAAT2 in motor neuron disease: And immunohistochemical study
    • A. E. Fray, P. G. Ince, S. J. Banner, et al., The expression of the glial glutamate transporter protein EAAT2 in motor neuron disease: and immunohistochemical study, Eur. J. Neurosci. 10, 2481-2489 (1998).
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 2481-2489
    • Fray, A.E.1    Ince, P.G.2    Banner, S.J.3
  • 22
    • 0033938202 scopus 로고    scopus 로고
    • Excitatory amino acid transporter 1 and 2 immunoreactivity in the spinal cord in amyotrophic lateral sclerosis
    • S. Sasaki, T. Komori, and M. Iwata, Excitatory amino acid transporter 1 and 2 immunoreactivity in the spinal cord in amyotrophic lateral sclerosis, Acta Neuropathol. Berlin 100, 138-144 (2000).
    • (2000) Acta Neuropathol. Berlin , vol.100 , pp. 138-144
    • Sasaki, S.1    Komori, T.2    Iwata, M.3
  • 23
    • 0028535070 scopus 로고
    • The role of glutamate in epilepsy and other CNS disorders
    • B. S. Meldrum, The role of glutamate in epilepsy and other CNS disorders, Neurology 44, S14-S23 (1994).
    • (1994) Neurology , vol.44
    • Meldrum, B.S.1
  • 24
    • 0035906526 scopus 로고    scopus 로고
    • Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity
    • K. Miyamoto, H. Nakanishi, S. Moriguchi, et al., Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity Brain Res. 901, 252-258 (2001).
    • (2001) Brain Res. , vol.901 , pp. 252-258
    • Miyamoto, K.1    Nakanishi, H.2    Moriguchi, S.3
  • 25
    • 27844505390 scopus 로고    scopus 로고
    • Protective effect of MK-801 in methylmercury-induced neuronal injury, in Mercury as a Global Pollutant
    • K. Miyamoto, K. Murao, J. Wakamiya, et al., Protective effect of MK-801 in methylmercury-induced neuronal injury, in Mercury as a Global Pollutant. 5th International Conference, p. 376 (1999).
    • (1999) 5th International Conference , pp. 376
    • Miyamoto, K.1    Murao, K.2    Wakamiya, J.3
  • 26
    • 0027221998 scopus 로고
    • NMDA-dependent superoxide production and neurotoxicity
    • M. Lafon-Cazal, S. Pietri, M. Culcasi, et al., NMDA-dependent superoxide production and neurotoxicity Nature 364, 535-537 (1993).
    • (1993) Nature , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pietri, S.2    Culcasi, M.3
  • 27
    • 70449138981 scopus 로고
    • A physiochemical rationale for the biological activity of mercury and its compounds
    • W. H. Hughes, A physiochemical rationale for the biological activity of mercury and its compounds, Ann. NY Acad. Sci. 65, 454-460 (1957).
    • (1957) Ann. NY Acad. Sci. , vol.65 , pp. 454-460
    • Hughes, W.H.1
  • 28
    • 0029793450 scopus 로고    scopus 로고
    • New mutations and phenotypes associated with glutamate and aspartate transport in Chinese Hamster ovary (CHO-K1) cells
    • R. P. Igo and J. F. Ash, New mutations and phenotypes associated with glutamate and aspartate transport in Chinese Hamster ovary (CHO-K1) cells, Somat. Cell. Mol. Genet. 22, 87-103 (1996).
    • (1996) Somat. Cell. Mol. Genet. , vol.22 , pp. 87-103
    • Igo, R.P.1    Ash, J.F.2
  • 29
    • 0027400784 scopus 로고
    • The role of sulfhydryl groups and calcium in the mercuric chloride-induced inhibition of glutamate uptake in rat primary astrocyte cultures
    • J. Albrecht, M. Talbot, H. K. Kimelberg, et al., The role of sulfhydryl groups and calcium in the mercuric chloride-induced inhibition of glutamate uptake in rat primary astrocyte cultures, Brain Res. 607, 249-254 (1993).
    • (1993) Brain Res. , vol.607 , pp. 249-254
    • Albrecht, J.1    Talbot, M.2    Kimelberg, H.K.3
  • 30
    • 0025011377 scopus 로고
    • Interactions of methylmercury with rat primary astrocyte cultures: Inhibition of rubidium and glutamate uptake and induction of swelling
    • M. Aschner, N. B. Eberle, K. Miller, et al., Interactions of methylmercury with rat primary astrocyte cultures: inhibition of rubidium and glutamate uptake and induction of swelling, Brain Res. 530, 245-250 (1990).
    • (1990) Brain Res. , vol.530 , pp. 245-250
    • Aschner, M.1    Eberle, N.B.2    Miller, K.3
  • 31
    • 0024446685 scopus 로고
    • 2 and methylmercury in astrocytes: Selectivity and reversibility
    • 2 and methylmercury in astrocytes: selectivity and reversibility, J. Neurochem. 53, 1228-1237 (1989).
    • (1989) J. Neurochem. , vol.53 , pp. 1228-1237
    • Brooks, N.1    Kristt, D.A.2
  • 32
    • 27844497048 scopus 로고    scopus 로고
    • 2) inhibits the in vitro uptake of glutamate in GLAST and GLT-1 transfected mutant CHO-K1 cells
    • To be published
    • 2) inhibits the in vitro uptake of glutamate in GLAST and GLT-1 transfected mutant CHO-K1 cells, Biol. Trace Element Res. To be published. (2005).
    • (2005) Biol. Trace Element Res.
    • Mutkus, L.1    Aschner, J.L.2    Syversen, T.3
  • 33
    • 22444445508 scopus 로고    scopus 로고
    • The in vitro uptake of glutamate in GLAST and GLT-1 transfected mutant CHO-K1 cells is inhibited by the ethylmercury-containing preservative, thimerosal
    • L. A. Mutkus, J. L. Aschner, T. Syversen, et al., The in vitro uptake of glutamate in GLAST and GLT-1 transfected mutant CHO-K1 cells is inhibited by the ethylmercury-containing preservative, thimerosal, Biol. Trace Element Res. 105, 71-86 (2005).
    • (2005) Biol. Trace Element Res. , vol.105 , pp. 71-86
    • Mutkus, L.A.1    Aschner, J.L.2    Syversen, T.3
  • 34
    • 2642518976 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression in heart of rats exposed to hypobaric hypoxia: Differential response between mRNA and protein
    • O. J. Birot, A. Peinnequin, N. Simler, et al., Vascular endothelial growth factor expression in heart of rats exposed to hypobaric hypoxia: differential response between mRNA and protein, J. Cell Physiol. 200, 107-115 (2004).
    • (2004) J. Cell Physiol. , vol.200 , pp. 107-115
    • Birot, O.J.1    Peinnequin, A.2    Simler, N.3
  • 35
    • 0033501641 scopus 로고    scopus 로고
    • Glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of GLAST
    • S. Duan, C. M. Anderson, B. A. Stein, et al., Glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of GLAST, J. Neurosci. 19, 10,193-10,200 (1999).
    • (1999) J. Neurosci. , vol.19
    • Duan, S.1    Anderson, C.M.2    Stein, B.A.3
  • 36
    • 0031014266 scopus 로고    scopus 로고
    • Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression
    • Y. Qian, A. Galli, S. Ramamoorthy et al., Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression, J. Neurosci. 17, 45-57 (1997).
    • (1997) J. Neurosci. , vol.17 , pp. 45-57
    • Qian, Y.1    Galli, A.2    Ramamoorthy, S.3
  • 37
    • 0032053985 scopus 로고    scopus 로고
    • Multiple signaling pathways regulate cell surface expression and activity of the excitatory amino acid carrier 1 subtype of Glu transporter in C6 glioma
    • K. E. Davis, D. J. Straff, E. A. Weinstein, et al., Multiple signaling pathways regulate cell surface expression and activity of the excitatory amino acid carrier 1 subtype of Glu transporter in C6 glioma, J. Neurosci. 18, 2475-2485 (1998).
    • (1998) J. Neurosci. , vol.18 , pp. 2475-2485
    • Davis, K.E.1    Straff, D.J.2    Weinstein, E.A.3
  • 38
    • 0028239794 scopus 로고
    • The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents
    • V. Petronilli, P. Costantini, L. Scorrano, et al., The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents, J. Biol. Chem. 269, 16,638-16,642 (1994).
    • (1994) J. Biol. Chem. , vol.269
    • Petronilli, V.1    Costantini, P.2    Scorrano, L.3
  • 39
    • 0028952437 scopus 로고
    • Differential modulation by sulfhydryl redox agents and glutathione of GABA- and glycineevoked currents in rat retinal ganglion cells
    • Z. H. Pan, R. Bahring, R., Grantyn, et al., Differential modulation by sulfhydryl redox agents and glutathione of GABA- and glycine-evoked currents in rat retinal ganglion cells, J. Neurosci. 15, 1384-1391 (1995).
    • (1995) J. Neurosci , vol.15 , pp. 1384-1391
    • Pan, Z.H.1    Bahring, R.2    Grantyn, R.3
  • 40
    • 0032434691 scopus 로고    scopus 로고
    • A reentrant loop domain in the glutamate carrier EAAT1 participates in substrate binding and translocation
    • R. P. Seal and S. G. Amara, A reentrant loop domain in the glutamate carrier EAAT1 participates in substrate binding and translocation, Neuron 21, 1487-1498 (1998).
    • (1998) Neuron , vol.21 , pp. 1487-1498
    • Seal, R.P.1    Amara, S.G.2
  • 41
    • 0032169137 scopus 로고    scopus 로고
    • Biotinylation of single cysteine mutant of the glutamate transporter GLT-1 from rat brain reveals its unusual topology
    • M. Grunewald, A. Bendahan, and B. I. Kanner, Biotinylation of single cysteine mutant of the glutamate transporter GLT-1 from rat brain reveals its unusual topology, Neuron 21, 623-632 (1998).
    • (1998) Neuron , vol.21 , pp. 623-632
    • Grunewald, M.1    Bendahan, A.2    Kanner, B.I.3
  • 42
    • 0032486463 scopus 로고    scopus 로고
    • Cysteine scanning of the surroundings of an alkali-ion binding site of the glutamate transporter GLT-1 reveals a conformationally sensitive residue
    • R. Zarbiv, M. Grunewald, M. P. Kavanaugh, et al., Cysteine scanning of the surroundings of an alkali-ion binding site of the glutamate transporter GLT-1 reveals a conformationally sensitive residue, J. Biol. Chem. 273, 14,231-14,237 (1998).
    • (1998) J. Biol. Chem. , vol.273
    • Zarbiv, R.1    Grunewald, M.2    Kavanaugh, M.P.3
  • 43
    • 0031001036 scopus 로고    scopus 로고
    • Neuronal and glial glutamate transporters possess and SH-based redox regulatory mechanism
    • D. Trotti, B. L. Rizzini, D. Rossi, et al., Neuronal and glial glutamate transporters possess and SH-based redox regulatory mechanism, Eur. J. Neurosci. 9, 1236-1243 (1997).
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 1236-1243
    • Trotti, D.1    Rizzini, B.L.2    Rossi, D.3
  • 44
    • 0032145886 scopus 로고    scopus 로고
    • Glutamate transporters are oxidant-vulnerable: A molecular link between oxidative and excitotoxic neurodegeneration?
    • D. Trotti, N. C. Danbolt, and A. Volterra, Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol. Sci. 8, 328-334 (1998).
    • (1998) Trends Pharmacol. Sci. , vol.8 , pp. 328-334
    • Trotti, D.1    Danbolt, N.C.2    Volterra, A.3
  • 45
    • 0029860263 scopus 로고    scopus 로고
    • Flux coupling in a neuronal glutamate transporter
    • N. Zerangue and M. P. Kavanaugh, Flux coupling in a neuronal glutamate transporter, Nature 383, 634-637 (1996).
    • (1996) Nature , vol.383 , pp. 634-637
    • Zerangue, N.1    Kavanaugh, M.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.