-
1
-
-
0032545433
-
Requirement for IL-13 independently of IL-4 in experimental asthma
-
Grunig, G., Warnock, M., Wakil, A. E. et al. 1998. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 282:2261.
-
(1998)
Science
, vol.282
, pp. 2261
-
-
Grunig, G.1
Warnock, M.2
Wakil, A.E.3
-
2
-
-
0032545213
-
Interleukin-13: Central mediator of allergic asthma
-
Wills-Karp, M., Luyimbazi, J., Xu, X. et al. 1998. Interleukin-13: central mediator of allergic asthma. Science 282:2258.
-
(1998)
Science
, vol.282
, pp. 2258
-
-
Wills-Karp, M.1
Luyimbazi, J.2
Xu, X.3
-
3
-
-
0034661356
-
Lineage commitment in the immune system: The T helper lymphocyte grows up
-
Glimcher, L. H. and Murphy, K. M. 2000. Lineage commitment in the immune system: The T helper lymphocyte grows up. Genes Dev. 14:1693.
-
(2000)
Genes Dev.
, vol.14
, pp. 1693
-
-
Glimcher, L.H.1
Murphy, K.M.2
-
4
-
-
13944277507
-
Mast cells as "tunable" effector and immunoregulatory cells: Recent advances
-
Galli, S. J., Kalesnikoff, J., Grimbaldeston, M. A., Piliponsky, A. M., Williams, C. M. and Tsai, M. 2005. Mast cells as "tunable" effector and immunoregulatory cells: Recent advances. Annu. Rev. Immunol. 23:749.
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 749
-
-
Galli, S.J.1
Kalesnikoff, J.2
Grimbaldeston, M.A.3
Piliponsky, A.M.4
Williams, C.M.5
Tsai, M.6
-
5
-
-
13944249962
-
Mast cells in the development of adaptive immune responses
-
Galli, S. J., Nakae, S. and Tsai, M. 2005. Mast cells in the development of adaptive immune responses. Nat. Immunol. 6:135.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 135
-
-
Galli, S.J.1
Nakae, S.2
Tsai, M.3
-
6
-
-
4344622415
-
Role of NFAT proteins in IL13 gene transcription in mast cells
-
Monticelli, S., Solymar, D. C. and Rao, A. 2004. Role of NFAT proteins in IL13 gene transcription in mast cells. J. Biol. Chem. 279:36210.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 36210
-
-
Monticelli, S.1
Solymar, D.C.2
Rao, A.3
-
7
-
-
0029008237
-
Characterization of the constitutive and inducible components of a T cell IL-4 activation responsive element
-
Tara, D., Weiss, D. L. and Brown, M. A. 1995. Characterization of the constitutive and inducible components of a T cell IL-4 activation responsive element. J. Immunol. 154:4592.
-
(1995)
J. Immunol.
, vol.154
, pp. 4592
-
-
Tara, D.1
Weiss, D.L.2
Brown, M.A.3
-
8
-
-
0029655781
-
Nuclear factor of activated T cells is associated with a mast cell interleukin 4 transcription complex
-
Weiss, D. L., Hural, J., Tara, D., Timmerman, L. A., Henkel, G. and Brown, M. A. 1996. Nuclear factor of activated T cells is associated with a mast cell interleukin 4 transcription complex. Mol. Cell. Biol. 16:228.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 228
-
-
Weiss, D.L.1
Hural, J.2
Tara, D.3
Timmerman, L.A.4
Henkel, G.5
Brown, M.A.6
-
9
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
Zheng, W. and Flavell, R. A. 1997. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89:587.
-
(1997)
Cell
, vol.89
, pp. 587
-
-
Zheng, W.1
Flavell, R.A.2
-
10
-
-
0030604714
-
The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4
-
Ho, I. C., Hodge, M. R., Rooney, J. W. and Glimcher, L. H. 1996. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 85:973.
-
(1996)
Cell
, vol.85
, pp. 973
-
-
Ho, I.C.1
Hodge, M.R.2
Rooney, J.W.3
Glimcher, L.H.4
-
11
-
-
0033567014
-
IL-4 production by mast cells does not require c-maf
-
Sherman, M. A., Nachman, T. Y. and Brown, M. 1999. IL-4 production by mast cells does not require c-maf. J. Immunol. 163:1733.
-
(1999)
J. Immunol.
, vol.163
, pp. 1733
-
-
Sherman, M.A.1
Nachman, T.Y.2
Brown, M.3
-
12
-
-
0026352777
-
GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene
-
Zon, L. I., Gurish, M. F., Stevens, R. L. et al. 1991. GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene. J. Biol. Chem. 266:22948.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 22948
-
-
Zon, L.I.1
Gurish, M.F.2
Stevens, R.L.3
-
13
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
Shimoda, K., van Deursen, J., Sangster, M. Y. et al. 1996. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 380:630.
-
(1996)
Nature
, vol.380
, pp. 630
-
-
Shimoda, K.1
van Deursen, J.2
Sangster, M.Y.3
-
14
-
-
15844404509
-
Essential role of Stat6 in IL-4 signalling
-
Takeda, K., Tanaka, T., Shi, W. et al. 1996. Essential role of Stat6 in IL-4 signalling. Nature 380:627.
-
(1996)
Nature
, vol.380
, pp. 627
-
-
Takeda, K.1
Tanaka, T.2
Shi, W.3
-
15
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
-
Kaplan, M. H., Schindler, U., Smiley, S. T. and Grusby, M. J. 1996. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4:313.
-
(1996)
Immunity
, vol.4
, pp. 313
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
16
-
-
0032960869
-
Stat6-independent production of IL-4 by mast cells
-
Sherman, M. A., Secor, V. H., Lee, S. K., Lopez, R. D. and Brown, M. 1999. Stat6-independent production of IL-4 by mast cells. Eur. J. Immunol. 29:1235.
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 1235
-
-
Sherman, M.A.1
Secor, V.H.2
Lee, S.K.3
Lopez, R.D.4
Brown, M.5
-
17
-
-
0028201726
-
Acquisition of lymphokine-producing phenotype by CD4+ T cells
-
Seder, R. A. and Paul, W. E. 1994. Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu. Rev. Immunol. 12:635.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 635
-
-
Seder, R.A.1
Paul, W.E.2
-
18
-
-
0034616398
-
Identification of a coordinate regulator of interleukin 4, 13 and 5 by cross-species sequence comparison
-
Loots, G. G., Locksley, R. M., Blankespoor, C. M. et al. 2000. Identification of a coordinate regulator of interleukin 4, 13 and 5 by cross-species sequence comparison. Science 288:136.
-
(2000)
Science
, vol.288
, pp. 136
-
-
Loots, G.G.1
Locksley, R.M.2
Blankespoor, C.M.3
-
19
-
-
14444281570
-
Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region
-
Frazer, K. A., Ueda, Y., Zhu, Y. et al. 1997. Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region. Genome Res. 7:495.
-
(1997)
Genome Res.
, vol.7
, pp. 495
-
-
Frazer, K.A.1
Ueda, Y.2
Zhu, Y.3
-
20
-
-
0037963472
-
Regulation of the Th2 cytokine locus by a locus control region
-
Lee, G. R., Fields, P. E., Griffin, T. J. and Flavell, R. A. 2003. Regulation of the Th2 cytokine locus by a locus control region. Immunity 19:145.
-
(2003)
Immunity
, vol.19
, pp. 145
-
-
Lee, G.R.1
Fields, P.E.2
Griffin, T.J.3
Flavell, R.A.4
-
21
-
-
8644220507
-
Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: A target for STAT6 but not GATA3
-
Lee, D. U. and Rao, A. 2004. Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: A target for STAT6 but not GATA3. Proc. Natl Acad. Sci. USA 101:16010.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 16010
-
-
Lee, D.U.1
Rao, A.2
-
22
-
-
12344250807
-
Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions
-
Lee, G. R., Spilianakis, C. G. and Flavell, R. A. 2005. Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions. Nat. Immunol. 6:42.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 42
-
-
Lee, G.R.1
Spilianakis, C.G.2
Flavell, R.A.3
-
23
-
-
10344234192
-
Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region
-
Fields, P. E., Lee, G. R., Kim, S. T., Bartsevich, V. V. and Flavell, R. A. 2004. Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region. Immunity 21:865.
-
(2004)
Immunity
, vol.21
, pp. 865
-
-
Fields, P.E.1
Lee, G.R.2
Kim, S.T.3
Bartsevich, V.V.4
Flavell, R.A.5
-
24
-
-
0038638583
-
An epigenetic view of helper T cell differentiation
-
Ansel, K. M., Lee, D. U. and Rao, A. 2003. An epigenetic view of helper T cell differentiation. Nat. Immunol. 4:616.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 616
-
-
Ansel, K.M.1
Lee, D.U.2
Rao, A.3
-
25
-
-
0023899769
-
Nuclease hypersensitive sites in chromatin
-
Gross, D. S. and Garrard, W. T. 1988. Nuclease hypersensitive sites in chromatin. Annu. Rev. Biochem. 57:159.
-
(1988)
Annu. Rev. Biochem.
, vol.57
, pp. 159
-
-
Gross, D.S.1
Garrard, W.T.2
-
26
-
-
4444364399
-
Bioinformatics for the 'bench biologist': How to find regulatory regions in genomic DNA
-
Nardone, J., Lee, D. U., Ansel, K. M. and Rao, A. 2004. Bioinformatics for the 'bench biologist': How to find regulatory regions in genomic DNA. Nat. Immunol. 5:768.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 768
-
-
Nardone, J.1
Lee, D.U.2
Ansel, K.M.3
Rao, A.4
-
27
-
-
0034254985
-
In vivo immunological function of mast cells derived from embryonic stem cells: An approach for the rapid analysis of even embryonic lethal mutations in adult mice in vivo
-
Tsai, M., Wedemeyer, J., Ganiatsas, S., Tam, S., Zom, L. I. and Galli, S. J. 2000. In vivo immunological function of mast cells derived from embryonic stem cells: An approach for the rapid analysis of even embryonic lethal mutations in adult mice in vivo. Proc. Natl Acad. Sci. USA 97:9186.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 9186
-
-
Tsai, M.1
Wedemeyer, J.2
Ganiatsas, S.3
Tam, S.4
Zom, L.I.5
Galli, S.J.6
-
28
-
-
0020372095
-
Mast cell clones: A model for the analysis of cellular maturation
-
Galli, S. J., Dvorak, A. M., Marcum, J. A. et al. 1982. Mast cell clones: A model for the analysis of cellular maturation. J. Cell Biol. 95:435.
-
(1982)
J. Cell Biol.
, vol.95
, pp. 435
-
-
Galli, S.J.1
Dvorak, A.M.2
Marcum, J.A.3
-
29
-
-
0035984591
-
A 3′ enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells
-
Solymar, D. C., Agarwal, S., Bassing, C. H., Alt, F. W. and Rao, A. 2002. A 3′ enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells. Immunity 17:41.
-
(2002)
Immunity
, vol.17
, pp. 41
-
-
Solymar, D.C.1
Agarwal, S.2
Bassing, C.H.3
Alt, F.W.4
Rao, A.5
-
30
-
-
0034675925
-
MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-kit ligand stimulation of ES cell-derived mast cells
-
Garrington, T. P., Ishizuka, T., Papst, P. J. et al. 2000. MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-kit ligand stimulation of ES cell-derived mast cells. EMBO J. 19:5387.
-
(2000)
EMBO J.
, vol.19
, pp. 5387
-
-
Garrington, T.P.1
Ishizuka, T.2
Papst, P.J.3
-
31
-
-
0032412441
-
Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
-
Agarwal, S. and Rao, A. 1998. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity 9:765.
-
(1998)
Immunity
, vol.9
, pp. 765
-
-
Agarwal, S.1
Rao, A.2
-
32
-
-
0029876439
-
Tissue-specific factors additively increase the probability of the all-or-none formation of a hypersensitive site
-
Boyes, J. and Felsenfeld, G. 1996. Tissue-specific factors additively increase the probability of the all-or-none formation of a hypersensitive site. EMBO J. 15:2496.
-
(1996)
EMBO J.
, vol.15
, pp. 2496
-
-
Boyes, J.1
Felsenfeld, G.2
-
33
-
-
0036305450
-
T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
-
Avni, O., Lee, D., Macian, F., Szabo, S. J., Glimcher, L. H. and Rao, A. 2002. T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat. Immunol. 3:643.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 643
-
-
Avni, O.1
Lee, D.2
Macian, F.3
Szabo, S.J.4
Glimcher, L.H.5
Rao, A.6
-
34
-
-
0033667895
-
Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo
-
Agarwal, S., Avni, O. and Rao, A. 2000. Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo. Immunity 12:643.
-
(2000)
Immunity
, vol.12
, pp. 643
-
-
Agarwal, S.1
Avni, O.2
Rao, A.3
-
35
-
-
0022006791
-
Neoplastic transformation of mast cells by Abelson MuLV: Abrogation of IL-3 dependence by a nonautocrine mechanism
-
Pierce, J. H., DiFiore, P. P., Aaronson, S. A. et al. 1985. Neoplastic transformation of mast cells by Abelson MuLV: Abrogation of IL-3 dependence by a nonautocrine mechanism. Cell 41:685.
-
(1985)
Cell
, vol.41
, pp. 685
-
-
Pierce, J.H.1
DiFiore, P.P.2
Aaronson, S.A.3
-
36
-
-
0342748481
-
In activated mast cells, IL-1 up-regulates the production of several Th2-related cytokines including IL-9
-
Hultner, L., Kolsch, S., Stassen, M. et al. 2000. In activated mast cells, IL-1 up-regulates the production of several Th2-related cytokines including IL-9. J. Immunol. 164:5556.
-
(2000)
J. Immunol.
, vol.164
, pp. 5556
-
-
Hultner, L.1
Kolsch, S.2
Stassen, M.3
-
37
-
-
0031593671
-
Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region
-
Takemoto, N., Koyano-Nakagawa, N., Yokota, T., Arai, N., Miyatake, S. and Arai, K. 1998. Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region. Int. Immunol. 10:1981.
-
(1998)
Int. Immunol.
, vol.10
, pp. 1981
-
-
Takemoto, N.1
Koyano-Nakagawa, N.2
Yokota, T.3
Arai, N.4
Miyatake, S.5
Arai, K.6
-
38
-
-
0036830465
-
Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus
-
Yamashita, M., Ukai-Tadenuma, M., Kimura, M. et al.. 2002. Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus. J. Biol. Chem. 277:42399.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42399
-
-
Yamashita, M.1
Ukai-Tadenuma, M.2
Kimura, M.3
-
39
-
-
12344308991
-
Deletion of a conserved II4 silencer impairs T helper type 1-mediated immunity
-
Ansel, K. M., Greenwald, R. J., Agarwal, S. et al. 2004. Deletion of a conserved II4 silencer impairs T helper type 1-mediated immunity. Nat. Immunol. 5:1251.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 1251
-
-
Ansel, K.M.1
Greenwald, R.J.2
Agarwal, S.3
-
40
-
-
18744416572
-
Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates
-
Walsh, J. C., DeKoter, R. P., Lee, H. et al. 2002. Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates. Immunity 17:665.
-
(2002)
Immunity
, vol.17
, pp. 665
-
-
Walsh, J.C.1
DeKoter, R.P.2
Lee, H.3
-
41
-
-
0032479989
-
PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors
-
DeKoter, R. P., Walsh, J. C. and Singh, H. 1998. PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/ macrophage progenitors. EMBO J. 17:4456.
-
(1998)
EMBO J.
, vol.17
, pp. 4456
-
-
DeKoter, R.P.1
Walsh, J.C.2
Singh, H.3
-
42
-
-
0036199657
-
PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors
-
DeKoter, R. P., Lee, H. and Singh, H. 2002. PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. Immunity 16:297.
-
(2002)
Immunity
, vol.16
, pp. 297
-
-
DeKoter, R.P.1
Lee, H.2
Singh, H.3
-
43
-
-
0030611964
-
PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors
-
Scott, E. W., Fisher, R. C., Olson, M. C. et al. 1997. PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors. Immunity 6:437.
-
(1997)
Immunity
, vol.6
, pp. 437
-
-
Scott, E.W.1
Fisher, R.C.2
Olson, M.C.3
-
44
-
-
0035261381
-
Genomic strategies to identify mammalian regulatory sequences
-
Pennacchio, L. A. and Rubin, E. M. 2001. Genomic strategies to identify mammalian regulatory sequences. Nat. Rev. Genet. 2:100.
-
(2001)
Nat. Rev. Genet.
, vol.2
, pp. 100
-
-
Pennacchio, L.A.1
Rubin, E.M.2
-
45
-
-
0036281949
-
T cell development: Bottoms-up
-
Hedrick, S. M. 2002. T cell development: Bottoms-up. Immunity 16:619.
-
(2002)
Immunity
, vol.16
, pp. 619
-
-
Hedrick, S.M.1
-
46
-
-
0035555263
-
Deletion of a coordinate regulator of type 2 cytokine expression in mice
-
Mohrs, M., Blankespoor, C. M., Wang, Z. E. et al. 2001. Deletion of a coordinate regulator of type 2 cytokine expression in mice. Nat. Immunol. 2:842.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 842
-
-
Mohrs, M.1
Blankespoor, C.M.2
Wang, Z.E.3
-
47
-
-
0026467244
-
A DNase I-hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer
-
Henkel, G., Weiss, D. L., McCoy, R., Deloughery, T., Tara, D. and Brown, M. A. 1992. A DNase I-hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer. J. Immunol. 149:3239.
-
(1992)
J. Immunol.
, vol.149
, pp. 3239
-
-
Henkel, G.1
Weiss, D.L.2
McCoy, R.3
Deloughery, T.4
Tara, D.5
Brown, M.A.6
-
48
-
-
0027939672
-
PU.1 and GATA: Components of a mast cell-specific interleukin 4 intronic enhancer
-
Henkel, G. and Brown, M. A. 1994. PU.1 and GATA: Components of a mast cell-specific interleukin 4 intronic enhancer. Proc. Natl Acad. Sci. USA 91:7737.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7737
-
-
Henkel, G.1
Brown, M.A.2
-
49
-
-
0034665507
-
An intron transcriptional enhancer element regulates IL-4 gene locus accessibility in mast cells
-
Hural, J. A., Kwan, M., Henkel, G., Hock, M. B. and Brown, M. 2000. An intron transcriptional enhancer element regulates IL-4 gene locus accessibility in mast cells. J. Immunol. 165:3239.
-
(2000)
J. Immunol.
, vol.165
, pp. 3239
-
-
Hural, J.A.1
Kwan, M.2
Henkel, G.3
Hock, M.B.4
Brown, M.5
-
50
-
-
0035887640
-
The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3
-
Kishikawa, H., Sun, J., Choi, A., Miaw, S. C. and Ho, I. C. 2001. The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3. J. Immunol. 167:4414.
-
(2001)
J. Immunol.
, vol.167
, pp. 4414
-
-
Kishikawa, H.1
Sun, J.2
Choi, A.3
Miaw, S.C.4
Ho, I.C.5
|