Nuclear factor of activated T cells is associated with a mast cell interleukin 4 transcription complex

Molecular and Cellular Biology

Volumn 16, Issue 1, 1996, Pages 228-235

  Weiss, Deborah L ^a   Hural, John ^b   Tara, David ^a   Timmerman, Luika A ^c   Henkel, Greg ^a,e   Brown, Melissa A ^a,b,d  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^e BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; DNA; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; NUCLEAR FACTOR; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; ELECTROPHORETIC MOBILITY; IMMUNOREGULATION; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DNA INTERACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION REGULATION;

ANIMAL; BASE SEQUENCE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; COMPARATIVE STUDY; CYCLOSPORINE; DNA; DNA-BINDING PROTEINS; GENES, REPORTER; INTERLEUKIN-4; MAST CELLS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0029655781     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.1.228     Document Type: Article

References (41)

1. + T-cell subsets Immunol. Rev. 123:5-22.
2. Abe, E., R. D. Malefyt, I. Matsuda, K. Arai, and N. Arai. 1992. An 11 bp DNA sequence motif apparently unique to the human IL-4 gene confers responsiveness to T cell activation signals. Proc Natl Acad. Sci. USA 89: 2864-2868.
3. Boulay, J.-L., and W. E. Paul. 1992. The interleukin-4 family of lymphokines. Curr Opin Immunol. 4:294-298.
4. Bruhn, K.W., K. Nelms, J.-L. Boulay, W. E. Paul, and M. J. Lenardo. 1993. Molecular dissection of the mouse interleukin-4 promoter. Proc. Natl. Acad. Sci. USA 90:9707-9711
5. Burd, P. R., H. W. Rogers, J. R. Gordon, C. A. Martin, S. Jayaraman, S. D. Wislon, A. M. Dvorak, S. J. Galli, and M. E. Dorf. 1989. Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokines. J Exp. Med. 170:245-257.
6. Chodosh, L. A., A. S. Baldwin, R. W. Carthew, and P. A. Sharp. 1988 Human CCAAT-binding proteins have heterologous subunits. Cell 53:11-54
7. Chuvpilo, S., C. Schomberg, R. Gerwig, A. Heinfling, R. Reeses, F. Grummt, and E. Serfling. 1993 Multiple closely-linked NFAT/octamer and HMGI(Y) binding sites are part of the interleukin 4 promoter. Nucleic Acids Res 21: 5694-5704.
8. Czarnetzki, B. M. 1987 Mechanisms and mediators in Urticaria Semin. Dermatol 6:272-279.
9. Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei Nucleic Acids Res. 11:1475-1489.
10. Fitch, F. W., M. D. McKisic, D. W. Lancki, and T. F. Gajewski. 1993. Differential regulation of murine T lymphocyte subsets. Annu. Rev. Immunol. 11:29-48.
11. Galli, S. J. 1993. New concepts about the mast cell. N. Engl J. Med. 328: 257-265
12. Hatfield, S. M., J. S. Mynderse, and N. W. Roehm. 1992 Rapamycin and FK506 differentially inhibit mast cell cytokine production and cytokine-induced proliferation and act as reciprocal anatagonists. J Pharmacol Exp. Ther 260:680-687
13. Henkel, G., and M. A. Brown. 1994. PU.1 and GATA: components of a mast cell-specific IL-4 specific enhancer Proc. Natl. Acad. Sci. USA 91:7737-7741.
14. Henkel, G., D. L. Weiss, R. McCoy, T. DeLoughery, D. Tara, and M. A. Brown. 1992. A DNase I hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer. J. Immunol. 149: 3239-3246.
15. Hoey, T., Y. L. Sun, K. Williamson, and X. Xu. 1995 Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins. Immunity 2:461-472.
16. Hsieh, C. S., A. B. Heimberger, J. S. Gold, A. O'Garra, and K. M. Murphy. 1992. Differential regulation of T helper phenotype development by interleukins 4 and 10 in alpha beta T-cell-receptor transgenic system. Proc. Natl. Acad. Sci. USA 89:6065-6069
17. Israel, A. 1994. NF-AT comes under control. Nature (London) 369:443-444.
18. Jain, J., P. G. McCaffrey, V. E. Valge-Archer, and A. Rao. 1992. Nuclear factor of activated T cells contains Fos and Jun. Nature (London) 356: 801-804.
19. Kaye, R. E., D. A. Fruman, B. E. Bierer, M. W. Albers, L. D. Zydowsky, S. I. Ho, Y.-J. Jin, M. C. Castells, S. L. Schrieber, C. T. Walsh, S. J. Burakoff, K. F. Austen, and H. R. Katz. 1992. Effects of cyclosporin A and FK506 on Fcε rector type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12. Proc. Natl. Acad. Sci. USA 89:8542-8546
20. Khavari, P. A., C. L. Peterson, J. W. Tamkum, D. B. Mendel, and G. R. Crabtree. 1993. Brg1 contains a conserved domain of the SW12/SNF2 family necessary for normal mitotic growth and transcription. Nature (London) 366:170-174.
21. +/ calmodulin-activated, phosphoprotein phosphatase calcineurin is sufficient for positive transcriptional regulation of the mouse IL-4 gene. Int. Immunol 6:179-188.
22. Lee, W., P. Mitchell, and R. Tjian. 1987. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell 49:741.
23. Li-Weber, M., A. Eder, H. Krafft-Czepa, and P. H. Krammer. 1992. T cell specific negative regulation of transcription of the human cytokine IL-4. J. Immunol 148:1913-1918.
24. Li-Weber, M., H. Krafft, and P. H. Krammer. 1993. A novel enhancer element in the human IL-4 promoter is suppressed by a position-independent silencer. J Immunol. 151:1371-1882
25. Maniatis, T., S. Goodbourn, and J. A. Fischer. 1987. Regulation of inducible and tissue-specific gene expression. Science 236:1237-1244.
26. Matsuda, I., E. S. Masuda, A. Tsuboi, S. Behman, N. Arai, and K. Arai. 1992. Characterization of NF(P), the nuclear factor that interacts with the regulatory P sequence (5′-CGAAAATTTCC-3′) of the human interleukin-4 gene, relationship to NF-κB and NF-AT. Biochem Biophys Res. Commun. 199:439-446.
27. McCaffrey, P. G., C. Luo, T. K. Kerppola, J. Jain, T. M. Badalian, A. M. Ho, E. Burgeon, W. S. Lane, J. N. Lambert, T. Curran, G. L. Versine, A. Rao, and P. G. Hogan. 1993. Isolation of the cyclosporin-sensitive T cell transcription factor NFATp. Science 262:750-734.
28. Northrop, J. P., S. N. Ho, L. Chen, D. J. Thomas, L. A. Timmerman, G. P. Nolan, A. Admon, and G. R. Crabtree. 1994. NF-AT components define a family of transcription factor targeted in T-cell activation. Nature (London) 369:497-502
29. Paul, W. E. 1991. Interleukin 4: a prototypic immunoregulatory lymphokine. Blood 77:1859-1870.
30. Pierce, J. H., P. P. DiFiore, S. A. Aaronson, M. Potter, J. Pumphrey, A. Scott, and J. Ihle. 1985. Neoplasic transformation of mast cells by Abelson MuLV. abrogation of IL-3 dependence by a nonautocrine mechanism. Cell 41: 685-693
31. Plaut, M., J. H. Pierce, C. J. Watson, J. Hanley-Hyde, R. P. Nordon, and W. E. Paul. 1989. Mast cell lines produce lymphokines in response to cross-linkage of the FcεRI or calcium ionophores Nature (London) 339:64-67.
32. Rao, A. 1994. NFATp, a transcription factor required for the coordinate induction of several cytokine genes Immunol. Today 15:274-281.
33. Rooney, J. W., M. R. Hodge, P. G. McCaffrey, A. Rao, and L. H. Glimcher. 1994. A common factor regulates both Th1 and Th2-specific cytokine gene expression EMBO J 13:625-633.
34. - T cells from T cell receptor transgenic mice. J Exp. Med. 176:1091-1098.
35. Swain, S. L., G. Huston, S. Tokonogy, and A. D. Weinberg. 1991. Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector cells that differ in lymphokine secretion pattern and cell surface phenotype. J. Immunol. 147:2991-3000.
36. c. Mol. Cell Biol 13:4793-4805.
37. Tara, D., D. L. Weiss, and M. A. Brown. 1993. An activation responsive element in the murine interleukin 4 gene is the site of an inducible DNA-protein interaction J. Immunol. 151:3617-3626.
38. Tara, D., D. L. Weiss, and M. A. Brown. 1995. Characterization of the constitutive and inducible components of a T cell IL-4 activation responsive element. J. Immunol 154:4592-4602.
39. Thompson, C. B., C.-Y. Wang, I.-C. Ho, P. R. Bohjanen, B. Petryniak, C. H. June, S. Miesfeldt, L. Zhang, G. J. Nabel, B. Karpinski, and J. M. Leiden. 1992. cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1, Mol. Cell. Biol. 12:1043-1053
40. Todd, M. D., M. J. Grusby, J. A. Lederer, E. Lacy, A. H. Lichtman, and L. H. Glimcher. 1993. Transcription of the interleukin 4 gene is regulated by multiple promoter elements. J Exp Med. 177:1663-1674.
41. Wodnar-Filipowicz, A., C. H. Heusser, and C. Moroni. 1989. Production of the haemopoietic growth factors GM-CSF and interleukin 3 by mast cells in response to IgE receptor-mediated activation Nature (London) 339:150-152.