DNA methyltransferase-3a interacts with p53 and represses p53-mediated gene expression

Cancer Biology and Therapy

Volumn 4, Issue 10, 2005, Pages 1138-1143

  Wang, Y Alan ^a,d   Kamarova, Yeugeniya ^a   Shen, Kate C ^a   Jiang, Zhongliang ^a   Hahn, Myong Joon ^b   Wang, Yaolin ^c   Brooks, S C ^a,d  

^a WAYNE STATE UNIVERSITY   (United States)

^b Sungkyunkwan University   (South Korea)

^c MERCK RESEARCH LABORATORIES   (United States)

^d NONE   (United States)

Author keywords

Chemoresistance; DNA methylation; DNA methyltransferases; DNMT3a; p21; p53; Transcriptional regulation

Indexed keywords

ANTIINFECTIVE AGENT; DEOXYCYTIDINE; DNA METHYLTRANSFERASE; ENZYME INHIBITOR; PROTEIN P53;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER THERAPY; CARCINOGENESIS; DEMETHYLATION; DNA DAMAGE; DNA METHYLATION; DNA REPLICATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE OVEREXPRESSION; GENE REPRESSION; GENOME; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSACTIVATION; TUMOR PROMOTION; UPREGULATION;

EID: 27744560484     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.4.10.2073     Document Type: Article

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