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Volumn 142, Issue 2, 2005, Pages 260-267

Short-term treatment with anti-CD44v7 antibody, but not CD44v4, restores the gut mucosa in established chronic dextran sulphate sodium (DSS)-induced colitis in mice

Author keywords

CD44 variant isoforms; CD44 variant therapy; Chronic inflammatory bowel disease

Indexed keywords

ANTIBODY; CD 44 VARIANT 4 ANTIBODY; CD 44 VARIANT 7 ANTIBODY; CD44V ANTIGEN; DEXTRAN SULFATE; ISOPROTEIN; MYELOPEROXIDASE; UNCLASSIFIED DRUG;

EID: 27644503980     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2005.02911.x     Document Type: Article
Times cited : (29)

References (38)
  • 1
    • 0346025500 scopus 로고    scopus 로고
    • Functional consequences of immune cell adhesion to endothelial cells
    • Rosemblatt M, Bono MR. Functional consequences of immune cell adhesion to endothelial cells. Curr Pharm Des 2004; 10:109-20.
    • (2004) Curr Pharm Des , vol.10 , pp. 109-120
    • Rosemblatt, M.1    Bono, M.R.2
  • 2
    • 0036935106 scopus 로고    scopus 로고
    • Abrogated lymphocyte infiltration and lowered CD14 in dextran sulfate induced colitis in mice treated with p65 antisense oligonucleotides
    • Spiik AK, Ridderstad A, Axelsson LG, Midtvedt T, Bjork L, Pettersson S. Abrogated lymphocyte infiltration and lowered CD14 in dextran sulfate induced colitis in mice treated with p65 antisense oligonucleotides. Int J Colorectal Dis 2002; 17:223-32.
    • (2002) Int J Colorectal Dis , vol.17 , pp. 223-232
    • Spiik, A.K.1    Ridderstad, A.2    Axelsson, L.G.3    Midtvedt, T.4    Bjork, L.5    Pettersson, S.6
  • 3
    • 0034782761 scopus 로고    scopus 로고
    • Quantification of mucosal leucocyte endothelial cell interaction by in vivo fluorescence microscopy in experimental colitis in mice
    • Farkas S, Herfarth H, Rossle M et al. Quantification of mucosal leucocyte endothelial cell interaction by in vivo fluorescence microscopy in experimental colitis in mice. Clin Exp Immunol 2001; 126:250-8.
    • (2001) Clin Exp Immunol , vol.126 , pp. 250-258
    • Farkas, S.1    Herfarth, H.2    Rossle, M.3
  • 4
    • 0023697064 scopus 로고
    • Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man
    • Jalkanen S, Jalkanen M, Bargatze R, Tammi M, Butcher EC. Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man. J Immunol 1988; 141:1615-23.
    • (1988) J Immunol , vol.141 , pp. 1615-1623
    • Jalkanen, S.1    Jalkanen, M.2    Bargatze, R.3    Tammi, M.4    Butcher, E.C.5
  • 6
    • 0033784987 scopus 로고    scopus 로고
    • CD44 supports T cell proliferation and apoptosis by apposition of protein kinases
    • Foger N, Marhaba R, Zoller M. CD44 supports T cell proliferation and apoptosis by apposition of protein kinases. Eur J Immunol 2000; 30:2888-99.
    • (2000) Eur J Immunol , vol.30 , pp. 2888-2899
    • Foger, N.1    Marhaba, R.2    Zoller, M.3
  • 7
    • 0035168660 scopus 로고    scopus 로고
    • Activated T lymphocytes regulate hyaluronan binding to monocyte CD44 via production of IL-2 and IFN-gamma
    • Levesque MC, Haynes BF. Activated T lymphocytes regulate hyaluronan binding to monocyte CD44 via production of IL-2 and IFN-gamma. J Immunol 2001; 166:188-96.
    • (2001) J Immunol , vol.166 , pp. 188-196
    • Levesque, M.C.1    Haynes, B.F.2
  • 8
    • 0032587164 scopus 로고    scopus 로고
    • TNFalpha and IL-4 regulation of hyaluronan binding to monocyte CD44 involves posttranslational modification of CD44
    • Levesque MC, Haynes BF. TNFalpha and IL-4 regulation of hyaluronan binding to monocyte CD44 involves posttranslational modification of CD44. Cell Immunol 1999; 193:209-18.
    • (1999) Cell Immunol , vol.193 , pp. 209-218
    • Levesque, M.C.1    Haynes, B.F.2
  • 9
    • 0031225365 scopus 로고    scopus 로고
    • Induction of IL-12 and chemokines by hyaluronan requires adhesion-dependent priming of resident but not elicited macrophages
    • Hodge-Dufour J, Noble PW, Horton MR et al. Induction of IL-12 and chemokines by hyaluronan requires adhesion-dependent priming of resident but not elicited macrophages. J Immunol 1997; 159:2492-500.
    • (1997) J Immunol , vol.159 , pp. 2492-2500
    • Hodge-Dufour, J.1    Noble, P.W.2    Horton, M.R.3
  • 10
    • 0038931747 scopus 로고    scopus 로고
    • Coupling of signal transduction to alternative pre-mRNA splicing by a composite splice regulator
    • Konig H, Ponta H, Herrlich P. Coupling of signal transduction to alternative pre-mRNA splicing by a composite splice regulator. EMBO J 1998; 17:2904-13.
    • (1998) EMBO J , vol.17 , pp. 2904-2913
    • Konig, H.1    Ponta, H.2    Herrlich, P.3
  • 11
    • 0026666626 scopus 로고
    • Participation in normal immune responses of a metastasis-inducing splice variant of CD44
    • Arch R, Wirth K, Hofmann M et al. Participation in normal immune responses of a metastasis-inducing splice variant of CD44. Science 1992; 257:682-5.
    • (1992) Science , vol.257 , pp. 682-685
    • Arch, R.1    Wirth, K.2    Hofmann, M.3
  • 12
    • 0025825209 scopus 로고
    • A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells
    • Gunthert U, Hofmann M, Rudy W et al. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 1991; 65:13-24.
    • (1991) Cell , vol.65 , pp. 13-24
    • Gunthert, U.1    Hofmann, M.2    Rudy, W.3
  • 13
    • 0032249736 scopus 로고    scopus 로고
    • Functional involvement of CD44, a family of cell adhesion molecules, in immune responses, tumour progression and haematopoiesis
    • Gunthert U, Schwarzler C, Wittig B et al. Functional involvement of CD44, a family of cell adhesion molecules, in immune responses, tumour progression and haematopoiesis. Adv Exp Med 1998; 451:43-9.
    • (1998) Adv Exp Med , vol.451 , pp. 43-49
    • Gunthert, U.1    Schwarzler, C.2    Wittig, B.3
  • 14
    • 0037442954 scopus 로고    scopus 로고
    • Expression of the CD44v2-10 isoform confers a metastatic phenotype: Importance of the heparan sulfate attachment site CD44v3
    • Barbour AP, Reeder JA, Walsh MD, Fawcett J, Antalis TM, Gotley DC. Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3. Cancer Res 2003; 63:887-92.
    • (2003) Cancer Res , vol.63 , pp. 887-892
    • Barbour, A.P.1    Reeder, J.A.2    Walsh, M.D.3    Fawcett, J.4    Antalis, T.M.5    Gotley, D.C.6
  • 15
    • 0027408671 scopus 로고
    • Prevention of tumor metastasis formation by anti-variant CD44
    • Seiter S, Arch R, Reber S et al. Prevention of tumor metastasis formation by anti-variant CD44. J Exp Med 1993; 177:443-55.
    • (1993) J Exp Med , vol.177 , pp. 443-455
    • Seiter, S.1    Arch, R.2    Reber, S.3
  • 16
    • 0030746538 scopus 로고    scopus 로고
    • Functional activity of murine CD44 variant isoforms in allergic and delayed type hypersensitivity
    • Wittig B, Seiter S, Foger N, Schwarzler C, Gunthert U, Zoller M. Functional activity of murine CD44 variant isoforms in allergic and delayed type hypersensitivity. Immunol Lett 1997; 57:217-23.
    • (1997) Immunol Lett , vol.57 , pp. 217-223
    • Wittig, B.1    Seiter, S.2    Foger, N.3    Schwarzler, C.4    Gunthert, U.5    Zoller, M.6
  • 17
    • 0034686511 scopus 로고    scopus 로고
    • Abrogation of experimental colitis correlates with increased apoptosis in mice deficient for CD44 variant exon 7 (CD44v7)
    • Wittig BM, Johansson B, Zoller M, Schwarzler C, Gunthert U. Abrogation of experimental colitis correlates with increased apoptosis in mice deficient for CD44 variant exon 7 (CD44v7). J Exp Med 2000; 191:2053-64.
    • (2000) J Exp Med , vol.191 , pp. 2053-2064
    • Wittig, B.M.1    Johansson, B.2    Zoller, M.3    Schwarzler, C.4    Gunthert, U.5
  • 18
    • 0029918501 scopus 로고    scopus 로고
    • Dextran sulfate sodium (DSS) induced experimental colitis in immunodeficient mice, effects in CD4(+)-cell depleted, athymic and NK-cell depleted SCID mice
    • Axelsson LG, Landstrom E, Goldschmidt TJ, Gronberg A, Bylund-Fellenius AC. Dextran sulfate sodium (DSS) induced experimental colitis in immunodeficient mice, effects in CD4(+)-cell depleted, athymic and NK-cell depleted SCID mice. Inflamm Res 1996; 45:181-91.
    • (1996) Inflamm Res , vol.45 , pp. 181-191
    • Axelsson, L.G.1    Landstrom, E.2    Goldschmidt, T.J.3    Gronberg, A.4    Bylund-Fellenius, A.C.5
  • 19
    • 0031015257 scopus 로고    scopus 로고
    • Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice
    • Kojouharoff G, Hans W, Obermeier F et al. Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice. Clin Exp Immunol 1997; 107:353-8.
    • (1997) Clin Exp Immunol , vol.107 , pp. 353-358
    • Kojouharoff, G.1    Hans, W.2    Obermeier, F.3
  • 21
    • 0032941175 scopus 로고    scopus 로고
    • Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice
    • Obermeier F, Kojouharoff G, Hans W, Scholmerich J, Gross V, Falk W. Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice. Clin Exp Immunol 1999; 116:238-45.
    • (1999) Clin Exp Immunol , vol.116 , pp. 238-245
    • Obermeier, F.1    Kojouharoff, G.2    Hans, W.3    Scholmerich, J.4    Gross, V.5    Falk, W.6
  • 22
    • 0032793928 scopus 로고    scopus 로고
    • Inhibition of dextran sulphate sodium (DSS)-induced colitis in mice by intracolonically administered antibodies against adhesion molecules endothelial leucocyte adhesion molecule-1 (ELAM-1) or intercellular adhesion molecule-1 (ICAM-1)
    • Hamamoto N, Maemura K, Hirata I, Murano M, Sasaki S, Katsu K. Inhibition of dextran sulphate sodium (DSS)-induced colitis in mice by intracolonically administered antibodies against adhesion molecules (endothelial leucocyte adhesion molecule-1 (ELAM-1) or intercellular adhesion molecule-1 (ICAM-1). Clin Exp Immunol 1999; 117:462-8.
    • (1999) Clin Exp Immunol , vol.117 , pp. 462-468
    • Hamamoto, N.1    Maemura, K.2    Hirata, I.3    Murano, M.4    Sasaki, S.5    Katsu, K.6
  • 23
    • 0242606051 scopus 로고    scopus 로고
    • Contrasting activity of cytosinguanosin dinucleotide oligonucleotides in mice with experimental colitis
    • Obermeier F, Dunger N, Strauch UG et al. Contrasting activity of cytosinguanosin dinucleotide oligonucleotides in mice with experimental colitis. Clin Exp Immunol 2003; 134:217-24.
    • (2003) Clin Exp Immunol , vol.134 , pp. 217-224
    • Obermeier, F.1    Dunger, N.2    Strauch, U.G.3
  • 25
    • 0034024741 scopus 로고    scopus 로고
    • Nuclear factor-kappa B activity and intestinal inflammation in dextran sulphate sodium (DSS)-induced colitis in mice is suppressed by gliotoxin
    • Herfarth H, Brand K, Rath HC, Rogler G, Scholmerich J, Falk W. Nuclear factor-kappa B activity and intestinal inflammation in dextran sulphate sodium (DSS)-induced colitis in mice is suppressed by gliotoxin. Clin Exp Immunol 2000; 120:59-65.
    • (2000) Clin Exp Immunol , vol.120 , pp. 59-65
    • Herfarth, H.1    Brand, K.2    Rath, H.C.3    Rogler, G.4    Scholmerich, J.5    Falk, W.6
  • 26
    • 0025891695 scopus 로고
    • T-cell memory: The connection between function, phenotype and migration pathways
    • Mackay CR. T-cell memory: the connection between function, phenotype and migration pathways. Immunol Today 1991; 12:189-92.
    • (1991) Immunol Today , vol.12 , pp. 189-192
    • Mackay, C.R.1
  • 27
    • 0034116088 scopus 로고    scopus 로고
    • The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion
    • Siegelman MH, Stanescu D, Estess P. The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion. J Clin Invest 2000; 105:683-91.
    • (2000) J Clin Invest , vol.105 , pp. 683-691
    • Siegelman, M.H.1    Stanescu, D.2    Estess, P.3
  • 28
    • 0029966274 scopus 로고    scopus 로고
    • CD44 and its ligand hyaluronate mediate rolling under physiologic flow: A novel lymphocyte-endothelial cell primary adhesion pathway
    • DeGrendele HC, Estess P, Picker LJ, Siegelman MH. CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte- endothelial cell primary adhesion pathway. J Exp Med 1996; 183:1119-30.
    • (1996) J Exp Med , vol.183 , pp. 1119-1130
    • Degrendele, H.C.1    Estess, P.2    Picker, L.J.3    Siegelman, M.H.4
  • 29
    • 0030690228 scopus 로고    scopus 로고
    • Requirement for CD44 in activated T cell extravasation into an inflammatory site
    • DeGrendele HC, Estess P, Siegelman MH. Requirement for CD44 in activated T cell extravasation into an inflammatory site. Science 1997; 278:672-5.
    • (1997) Science , vol.278 , pp. 672-675
    • Degrendele, H.C.1    Estess, P.2    Siegelman, M.H.3
  • 30
    • 0242551584 scopus 로고    scopus 로고
    • Homing and cellular traffic in lymph nodes
    • Von Andrian UH, Mempel TR. Homing and cellular traffic in lymph nodes. Nat Rev Immunol 2003; 3:867-78.
    • (2003) Nat Rev Immunol , vol.3 , pp. 867-878
    • Von Andrian, U.H.1    Mempel, T.R.2
  • 31
    • 0043071554 scopus 로고    scopus 로고
    • CD44v7 interferes with activation-induced cell death by up-regulation of anti-apoptotic gene expression
    • Marhaba R, Bourouba M, Zoller M. CD44v7 interferes with activation-induced cell death by up-regulation of anti-apoptotic gene expression. J Leukoc Biol 2003; 74:135-48.
    • (2003) J Leukoc Biol , vol.74 , pp. 135-148
    • Marhaba, R.1    Bourouba, M.2    Zoller, M.3
  • 32
    • 0033020640 scopus 로고    scopus 로고
    • CD44 variant isoforms on blood leukocytes in chronic inflammatory bowel disease and other systemic autoimmune diseases
    • Wittig B, Seiter S, Schmidt DS, Zuber M, Neurath M, Zoller M. CD44 variant isoforms on blood leukocytes in chronic inflammatory bowel disease and other systemic autoimmune diseases. Lab Invest 1999; 79:747-59.
    • (1999) Lab Invest , vol.79 , pp. 747-759
    • Wittig, B.1    Seiter, S.2    Schmidt, D.S.3    Zuber, M.4    Neurath, M.5    Zoller, M.6
  • 33
    • 0038480148 scopus 로고    scopus 로고
    • The gut as an organ of immunology
    • Wittig BM, Zeitz M. The gut as an organ of immunology. Int J Colorectal Dis 2003; 18:181-7.
    • (2003) Int J Colorectal Dis , vol.18 , pp. 181-187
    • Wittig, B.M.1    Zeitz, M.2
  • 34
    • 0037616163 scopus 로고    scopus 로고
    • Targeting dendritic cells with CD44 monoclonal antibodies selectively inhibits the proliferation of naive CD4+ T-helper cells by induction of FAS-independent T-cell apoptosis
    • Termeer C, Averbeck M, Hara H et al. Targeting dendritic cells with CD44 monoclonal antibodies selectively inhibits the proliferation of naive CD4+ T-helper cells by induction of FAS-independent T-cell apoptosis. Immunology 2003; 109:32-40.
    • (2003) Immunology , vol.109 , pp. 32-40
    • Termeer, C.1    Averbeck, M.2    Hara, H.3
  • 35
    • 0032134179 scopus 로고    scopus 로고
    • Curative treatment of an experimentally induced colitis by a CD44 variant V7-specific antibody
    • Wittig B, Schwarzler C, Fohr N, Gunthert U, Zoller M. Curative treatment of an experimentally induced colitis by a CD44 variant V7-specific antibody. J Immunol 1998; 161:1069-73.
    • (1998) J Immunol , vol.161 , pp. 1069-1073
    • Wittig, B.1    Schwarzler, C.2    Fohr, N.3    Gunthert, U.4    Zoller, M.5
  • 36
    • 0033978595 scopus 로고    scopus 로고
    • The CD44 variant isoforms CD44v6 and CD44v7 are expressed by distinct leukocyte subpopulations and exert non-overlapping functional activities
    • Seiter S, Schmidt DS, Zoller M. The CD44 variant isoforms CD44v6 and CD44v7 are expressed by distinct leukocyte subpopulations and exert non-overlapping functional activities. Int Immunol 2000; 12:37-49.
    • (2000) Int Immunol , vol.12 , pp. 37-49
    • Seiter, S.1    Schmidt, D.S.2    Zoller, M.3
  • 37
    • 0035021027 scopus 로고    scopus 로고
    • Osteopontin as a means to cope with environmental insults, regulation of inflammation, tissue remodeling, and cell survival
    • Denhardt DT, Noda M, O'Regan AW, Pavlin D, Berman JS. Osteopontin as a means to cope with environmental insults, regulation of inflammation, tissue remodeling, and cell survival. J Clin Invest 2001; 107:1055-61.
    • (2001) J Clin Invest , vol.107 , pp. 1055-1061
    • Denhardt, D.T.1    Noda, M.2    O'Regan, A.W.3    Pavlin, D.4    Berman, J.S.5
  • 38
    • 0032926684 scopus 로고    scopus 로고
    • CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis
    • Katagiri YU, Sleeman J, Fujii H et al. CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis. Cancer Res 1999; 59:219-26.
    • (1999) Cancer Res , vol.59 , pp. 219-226
    • Katagiri, Y.U.1    Sleeman, J.2    Fujii, H.3


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