Signal transduction pathways of group I metabotropic glutamate receptor-induced long-term depression at sensory spinal synapses

Pain

Volumn 118, Issue 1-2, 2005, Pages 145-154

  Heinke, Bernhard ^a   Sandkühler, Jürgen ^a  

^a Medical University of Vienna   (Austria)

Author keywords

(S) 3,5 DHPG; Intracellular Ca2+ stores; L type VDCC; Nociception; Protein kinase C; Rat

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; 3,5 DIHYDROXYPHENYLGLYCINE; BISINDOLYLMALEIMIDE; CALCIUM ION; CHELERYTHRINE; CONTINUOUS ERYTHROPOIESIS RECEPTOR ACTIVATOR; CYCLOPIAZONIC ACID; INOSITOL 1,4,5 TRISPHOSPHATE; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR AGONIST; NIFEDIPINE; PROTEIN KINASE C INHIBITOR; RYANODINE; THAPSIGARGIN;

AFFERENT NERVE GROUP 1; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DORSAL ROOT; EVOKED RESPONSE; FEMALE; LONG TERM DEPRESSION; MALE; NERVE CELL; NONHUMAN; PATCH CLAMP; PREMEDICATION; PRIORITY JOURNAL; RAT; SENSORY NERVE; SIGNAL TRANSDUCTION; SPINAL NERVE; SYNAPSE;

ANIMALS; BENZOATES; CALCIUM; DISEASE MODELS, ANIMAL; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GLYCINE; INTRACELLULAR SPACE; LONG-TERM DEPRESSION (PHYSIOLOGY); MALE; NEURONS, AFFERENT; NOCICEPTORS; PATCH-CLAMP TECHNIQUES; POSTERIOR HORN CELLS; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; RESORCINOLS; SIGNAL TRANSDUCTION; SPINAL CORD; SYNAPSES; THAPSIGARGIN;

EID: 27644487894     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2005.08.004     Document Type: Article

References (72)

1. AHP in rat dentate granule neurons J Neurophysiol 76 1996 2691 2700
2. H. Adwanikar, F. Karim, and R.W. Gereau Inflammation persistently enhances nocifensive behaviors mediated by spinal group I mGluRs through sustained ERK activation Pain 111 2004 125 135
3. F.J. Alvarez, R.M. Villalba, P.A. Carr, P. Grandes, and P.M. Somohano Differential distribution of metabotropic glutamate receptors 1a, 1b, and 5 in the rat spinal cord J Comp Neurol 422 2000 464 487
4. 2+-ATPase inhibitor thapsigargin on spinal nociception in rats Pharmacology 62 2001 145 150
5. R.B. Avery, and D. Johnston Multiple channel types contribute to the low-voltage-activated calcium current in hippocampal CA3 pyramidal neurons J Neurosci 16 1996 5567 5582
6. J.J. Azkue, X.G. Liu, M. Zimmermann, and J Sandkühler Induction of long-term potentiation of C fibre-evoked spinal field potentials requires recruitment of group I, but not group II/III metabotropic glutamate receptors Pain 106 2003 373 379
7. M.A. Bernstein, and S.P. Welch Alterations in L-type calcium channels in the brain and spinal cord of acutely treated and morphine-tolerant mice Brain Res 696 1995 83 88
8. J.H. Bian, T.K. Ghosh, J.C. Wang, and D.L. Gill Identification of intracellular calcium pools. Selective modification by thapsigargin J Biol Chem 266 1991 8801 8806
9. 2+ rises in hippocampal pyramidal cells J Neurophysiol 81 1999 2903 2913
10. T.V. Bliss, and G.L. Collingridge A synaptic model of memory: long-term potentiation in the hippocampus Nature 361 1993 31 39
11. Z.A. Bortolotto, S.M. Fitzjohn, and G.L. Collingridge Roles of metabotropic glutamate receptors in LTP and LTD in the hippocampus Curr Opin Neurobiol 9 1999 299 304
12. P. Chavis, L. Fagni, J.B. Lansman, and J. Bockaert Functional coupling between ryanodine receptors and L-type calcium channels in neurons Nature 382 1996 719 722
13. J. Chen, and J. Sandkühler Induction of homosynaptic long-term depression at spinal synapses of sensory Aδ-fibers requires activation of metabotropic glutamate receptors. Neuroscience 98 2000 141 148
14. J. Chen, B. Heinke, and J. Sandkühler Activation of group I metabotropic glutamate receptors induces long-term depression at sensory synapses in superficial spinal dorsal horn Neuropharmacology 39 2000 2231 2243
15. B.R. Christie, and W.C. Abraham L-type voltage-sensitive calcium channel antagonists block heterosynaptic long-term depression in the dentate gyrus of anaesthetized rats Neurosci Lett 167 1994 41 45
16. P.J. Conn, and J.P. Pin Pharmacology and functions of metabotropic glutamate receptors Annu Rev Pharmacol Toxicol 37 1997 205 237
17. S. Dolan, and A.M. Nolan Behavioral evidence supporting a differential role for spinal group I and II metabotropic glutamate receptors in inflammatory hyperalgesia in sheep Neuropharmacology 43 2002 319 326
18. T. Endoh Characterization of modulatory effects of postsynaptic metabotropic glutamate receptors on calcium currents in rat nucleus tractus solitarius Brain Res 1024 2004 212 224
19. K. Fisher, and T.J. Coderre Hyperalgesia and allodynia induced by intrathecal (RS)-dihydroxyphenylglycine in rats NeuroReport 9 1998 1169 1172
20. M.E. Fundytus Glutamate receptors and nociception: implications for the drug treatment of pain CNS Drugs 15 2001 29 58
21. 1) alleviates pain and restores opioid efficacy after nerve injury in rats Br J Pharmacol 132 2001 354 367
22. S.M. Garraway, J.C. Petruska, and L.M. Mendell BDNF sensitizes the response of lamina II neurons to high threshold primary afferent inputs Eur J Neurosci 18 2003 2467 2476
23. G. Gerber, D.H. Youn, C.H. Hsu, D. Isaev, and M. Randic Spinal dorsal horn synaptic plasticity: involvement of group I metabotropic glutamate receptors J. Sandkühler B. Bromm G.F. Gebhart Nervous system plasticity and chronic pain 2000 Elsevier Amsterdam 115 134
24. W. Guo, F. Wei, S. Zou, M.T. Robbins, S. Sugiyo, T. Ikeda, J.C. Tu, P.F. Worley, R. Dubner, and K. Ren Group I metabotropic glutamate receptor NMDA receptor coupling and signaling cascade mediate spinal dorsal horn NMDA receptor 2B tyrosine phosphorylation associated with inflammatory hyperalgesia J Neurosci 24 2004 9161 9173
25. J.M. Herbert, J.M. Augereau, J. Gleye, and J.P. Maffrand Chelerythrine is a potent and specific inhibitor of protein kinase C Biochem Biophys Res Commun 172 1990 993 999
26. E. Hermans, and R.A. Challiss Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors Biochem J 359 2001 465 484
27. O.J. Igwe, and B.M. Chronwall Hyperalgesia induced by peripheral inflammation is mediated by protein kinase C βII isozyme in the rat spinal cord Neuroscience 104 2001 875 890
28. H. Ikeda, B. Heinke, R. Ruscheweyh, and J Sandkühler Synaptic plasticity in spinal lamina I projection neurons that mediate hyperalgesia Science 299 2003 1237 1240
29. I. Ito, A. Kohda, S. Tanabe, E. Hirose, M. Hayashi, S. Mitsunaga, and H. Sugiyama 3,5-Dihydroxyphenyl-glycine: a potent agonist of metabotropic glutamate receptors NeuroReport 3 1992 1013 1061
30. H. Jia, A. Rustioni, and J.G. Valtschanoff Metabotropic glutamate receptors in superficial laminae of the rat dorsal horn J Comp Neurol 410 1999 627 642
31. Y. Kawasaki, T. Kohno, Z.Y. Zhuang, G.J. Brenner, H. Wang, M.C. Van Der, K. Befort, C.J. Woolf, and R.R. Ji Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization J Neurosci 24 2004 8310 8321
32. N. Kemp, and Z.I. Bashir Long-term depression: a cascade of induction and expression mechanisms Prog Neurobiol 65 2001 339 365
33. P. Kettunen, P. Krieger, D. Hess, and A El Manira Signaling mechanisms of metabotropic glutamate receptor 5 subtype and its endogenous role in a locomotor network J Neurosci 22 2002 1868 1873
34. 2+ channels activating at negative voltages J Biol Chem 276 2001 22100 22106
35. C.L. Linn Second messenger pathways involved in up-regulation of an L-type calcium channel Vis Neurosci 17 2000 473 482
36. 2+ levels affect plasticity differently: the LTP zone, the LTD zone and no man's land J Physiol 532 2001 285
37. 2+ concentration of hippocampal CA1 pyramidal neurons J Neurophysiol 76 1996 3460 3470
38. A.B. Malmberg, C. Chen, S. Tonegawa, and A.I. Basbaum Preserved acute pain and reduced neuropathic pain in mice lacking PKCγ Science 278 1997 279 283
39. L. Mao, and J.Q. Wang Group I metabotropic glutamate receptor-mediated calcium signalling and immediate early gene expression in cultured rat striatal neurons Eur J Neurosci 17 2003 741 750
40. 2+ release J Biochem 122 1997 498 505
41. K.A. Moore, H. Baba, and C.J. Woolf Synaptic transmission and plasticity in the superficial dorsal horn J. Sandkühler B. Bromm G.F. Gebhart Nervous system plasticity and chronic pain 2000 Elsevier Amsterdam 63 81
42. V. Neugebauer Metabotropic glutamate receptors - important modulators of nociception and pain behavior Pain 98 2002 1 8
43. V. Neugebauer, P.S. Chen, and W.D. Willis Jr Role of metabotropic glutamate receptor subtype mGluR1 in brief nociception and central sensitization of primate STT cells J Neurophysiol 82 1999 272 282
44. 2+ channels J Neurosci 20 2000 8290 8297
45. M. Ohsawa, and J. Kamei Role of intracellular calcium in thermal allodynia and hyperalgesia in diabetic mice Brain Res 833 1999 278 281
46. S.M. O'Mara, M.J. Rowan, and R. Anwyl Dantrolene inhibits long-term depression and depotentiation of synaptic transmission in the rat dentate gyrus Neuroscience 68 1995 621 624
47. 2+ channels Brain Res Rev 40 2002 223 229
48. M. Randic, M.C. Jiang, and R. Cerne Long-term potentiation and long-term depression of primary afferent neurotransmission in the rat spinal cord J Neurosci 13 1993 5228 5241
49. 2+ from separate presynaptic and postsynaptic intracellular stores J Neurosci 16 1996 5951 5960
50. J. Rodrigo, A.M. Suburo, M.L. Bentura, T. Fernandez, S. Nakade, K. Mikoshiba, R. Martinez-Murillo, and J.M. Polak Distribution of the inositol 1,4,5-trisphosphate receptor, P400, in adult rat brain J Comp Neurol 337 1993 493 517
51. A.M. Rush, J. Wu, M.J. Rowan, and R. Anwyl Group I metabotropic glutamate receptor (mGluR)-dependent long-term depression mediated via p38 mitogen-activated protein kinase is inhibited by previous high-frequency stimulation and activation of mGluRs and protein kinase C in the rat dentate gyrus in vitro J Neurosci 22 2002 6121 6128
52. J. Sandkühler Learning and memory in pain pathways Pain 88 2000 113 118
53. Sandkühler J. Long-lasting analgesia following TENS and acupuncture: spinal mechanisms beyond gate control. In: Devor M, Rowbotham MC, editors. Proc. IXth World Congress on Pain, vol. 16. Seattle: IASP Press; 2000b. pp. 359-69.
54. J. Sandkühler, and H. Ikeda Two forms of synaptic long-term potentiation in ascending pain pathways Soc Neurosci Abstr 2003 131
55. J Sandkühler, and X. Liu Induction of long-term potentiation at spinal synapses by noxious stimulation or nerve injury Eur J Neurosci 10 1998 2476 2480
56. J. Sandkühler, J.G. Chen, G. Cheng, and M. Randic Low-frequency stimulation of afferent Aδ-fibers induces long-term depression at primary afferent synapses with substantia gelatinosa neurons in the rat J Neurosci 17 1997 6483 6491
57. R. Schnabel, I.C. Kilpatrick, and G.L. Collingridge An investigation into signal transduction mechanisms involved in DHPG-induced LTD in the CA1 region of the hippocampus Neuropharmacology 38 1999 1585 1596
58. R. Schnabel, I.C. Kilpatrick, and G.L. Collingridge Protein phosphatase inhibitors facilitate DHPG-induced LTD in the CA1 region of the hippocampus Br J Pharmacol 132 2001 1095 1101
59. A.H. Sharp, T.M. Dawson, C.A. Ross, M. Fotuhi, R.J. Mourey, and S.H. Snyder Inositol 1,4,5-trisphosphate receptors: immunohistochemical localization to discrete areas of rat central nervous system Neuroscience 53 1993 927 942
60. L.C. Stanfa, and A.H. Dickenson Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones Eur J Pharmacol 347 1998 165 172
61. G. Svirskis, and J. Hounsgaard Transmitter regulation of plateau properties in turtle motoneurons J Neurophysiol 79 1998 45 50
62. F.R. Tang, and M.K. Sim Pre- and/or post-synaptic localisation of metabotropic glutamate receptor 1α (mGluR1α) and 2/3 (mGluR2/3) in the rat spinal cord Neurosci Res 34 1999 73 78
63. D. Toullec, P. Pianetti, H. Coste, P. Bellevergue, T. Grand-Perret, M. Ajakane, V. Baudet, P. Boissin, E. Boursier, and F. Loriolle The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C J Biol Chem 266 1991 15771 15781
64. Z. Vidnyanszky, J. Hamori, L. Negyessy, D. Ruegg, T. Knöpfel, R. Kuhn, and T.J. Gorcs Cellular and subcellular localization of the mGluR5a metabotropic glutamate receptor in rat spinal cord NeuroReport 6 1994 209 213
65. N.V. Voitenko, E.P. Kostyuk, I.A. Kruglikov, and P.G. Kostyuk Changes in calcium signalling in dorsal horn neurons in rats with streptozotocin-induced diabetes Neuroscience 94 1999 887 890
66. 2+ from intracellular stores J Neurophysiol 77 1997 812 825
67. 2+ channel subtypes on rat spinal motor neurons, interneurons, and nerve terminals J Neurosci 18 1998 6319 6330
68. W.D. Willis Jr Long-term potentiation in spinothalamic neurons Brain Res Rev 40 2002 202 214
69. J. Wu, A. Rush, M. Rowan, and R. Anwyl NMDA receptor- and metabotropic glutamate receptor-dependent synaptic plasticity induced by high frequency stimulation in the rat dentate gyrus in vitro J Physiol 533 2001 745 755
70. K. Yashpal, K. Fisher, J.G. Chabot, and T.J. Coderre Differential effects of NMDA and group I mGluR antagonists on both nociception and spinal cord protein kinase C translocation in the formalin test and a model of neuropathic pain in rats Pain 94 2001 17 29
71. J. Zhong, G. Gerber, L. Kojic, and M. Randic Dual modulation of excitatory synaptic transmission by agonists at group I metabotropic glutamate receptors in the rat spinal dorsal horn Brain Res 887 2000 359 377
72. R.D. Zühlke, G.S. Pitt, K. Deisseroth, R.W. Tsien, and H. Reuter Calmodulin supports both inactivation and facilitation of L-type calcium channels Nature 399 1999 159 162