-
1
-
-
0013218415
-
-
(eds) 3rd edn. Oxford University Press, Oxford
-
Bates, G.P., Harper, P.S. and Jones, A.L. (eds) (2002) Huntington's Disease, 3rd edn. Oxford University Press, Oxford.
-
(2002)
Huntington's Disease
-
-
Bates, G.P.1
Harper, P.S.2
Jones, A.L.3
-
2
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DiFiglia, M., Sapp, E., Chase, K.O., Davies, S.W., Bates, G.P., Vonsattel, J.P. and Aronin, N. (1997) Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science, 277, 1990-1993.
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
Aronin, N.7
-
3
-
-
0031918640
-
Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: Correlation between the density of inclusions and IT15 CAG triplet repeat length
-
Becher, M.W., Kotzuk, J.A., Sharp, A.H., Davies, S.W., Bates, G.P., Price, D.L. and Ross, C.A. (1998) Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length. Neurobiol. Dis., 4, 387-397.
-
(1998)
Neurobiol. Dis.
, vol.4
, pp. 387-397
-
-
Becher, M.W.1
Kotzuk, J.A.2
Sharp, A.H.3
Davies, S.W.4
Bates, G.P.5
Price, D.L.6
Ross, C.A.7
-
4
-
-
0033119123
-
Nuclear and neuropil aggregates in Huntington's disease: Relationship to neuropathology
-
Gutekunst, C.A., Li, S.H., Yi, H., Mulroy, J.S., Kuemmerle, S., Jones, R., Rye, D., Ferrante, R.J., Hersch, S.M. and Li, X.J. (1999) Nuclear and neuropil aggregates in Huntington's disease: Relationship to neuropathology. J. Neurosci., 19, 2522-2534.
-
(1999)
J. Neurosci.
, vol.19
, pp. 2522-2534
-
-
Gutekunst, C.A.1
Li, S.H.2
Yi, H.3
Mulroy, J.S.4
Kuemmerle, S.5
Jones, R.6
Rye, D.7
Ferrante, R.J.8
Hersch, S.M.9
Li, X.J.10
-
5
-
-
3242692878
-
The polyglutamine diseases
-
Bates, G.P., Harper, P.S. and Jones, A.L. (eds), 3rd edn. Oxford University Press, Oxford
-
Bates, G.P. and Benn, C. (2002) The polyglutamine diseases. In Bates, G.P., Harper, P.S. and Jones, A.L. (eds), Huntington's Disease, 3rd edn. Oxford University Press, Oxford, pp. 429-472.
-
(2002)
Huntington's Disease
, pp. 429-472
-
-
Bates, G.P.1
Benn, C.2
-
6
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini, L., Sathasivam, K., Seller, M., Cozens, B., Harper, A., Hetherington, C., Lawton, M., Trottier, Y., Lehrach, H., Davies, S.W. et al. (1996) Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell, 87, 493-506.
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
-
7
-
-
0033560924
-
Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation
-
Carter, R.J., Lione, L.A., Humby, T., Mangiarini, L., Mahal, A., Bates, G.P., Dunnett, S.B. and Morton, A.J. (1999) Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation. J. Neurosci., 19, 3248-3257.
-
(1999)
J. Neurosci.
, vol.19
, pp. 3248-3257
-
-
Carter, R.J.1
Lione, L.A.2
Humby, T.3
Mangiarini, L.4
Mahal, A.5
Bates, G.P.6
Dunnett, S.B.7
Morton, A.J.8
-
8
-
-
0033500593
-
Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation
-
Lione, L.A., Carter, R.J., Hunt, M.J., Bates, G.P., Morton, A.J. and Dunnett, S.B. (1999) Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation. J. Neurosci., 19, 10428-10437.
-
(1999)
J. Neurosci.
, vol.19
, pp. 10428-10437
-
-
Lione, L.A.1
Carter, R.J.2
Hunt, M.J.3
Bates, G.P.4
Morton, A.J.5
Dunnett, S.B.6
-
9
-
-
0036670407
-
Huntingtin fragments that aggregate go their separate ways
-
DiFiglia, M. (2002) Huntingtin fragments that aggregate go their separate ways. Mol. Cell, 10, 224-225.
-
(2002)
Mol. Cell
, vol.10
, pp. 224-225
-
-
DiFiglia, M.1
-
10
-
-
19944427749
-
Orexin loss in Huntington's disease
-
Petersen, A., Gil, J., Maat-Schieman, M.L., Bjorkqvist, M., Tanila, H., Araujo, I.M., Smith, R., Popovic, N., Wierup, N., Norlen, P. et al. (2005) Orexin loss in Huntington's disease. Hum. Mol. Genet., 14, 39-47.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 39-47
-
-
Petersen, A.1
Gil, J.2
Maat-Schieman, M.L.3
Bjorkqvist, M.4
Tanila, H.5
Araujo, I.M.6
Smith, R.7
Popovic, N.8
Wierup, N.9
Norlen, P.10
-
11
-
-
25844526181
-
Gene expression in Huntington's disease skeletal muscle: A potential biomarker
-
Strand, A.D., Aragaki, A.K., Shaw, D., Bird, T., Holton, J., Turner, C., Tapscott, S.J., Tabrizi, S.J., Schapira, A., Kooperberg, C.L. et al. (2005) Gene expression in Huntington's disease skeletal muscle: A potential biomarker. Hum. Mol. Genet., 14, 1863-1876.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 1863-1876
-
-
Strand, A.D.1
Aragaki, A.K.2
Shaw, D.3
Bird, T.4
Holton, J.5
Turner, C.6
Tapscott, S.J.7
Tabrizi, S.J.8
Schapira, A.9
Kooperberg, C.L.10
-
12
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
Davies, S.W., Turmaine, M., Cozens, B.A., DiFiglia, M., Sharp, A.H., Ross, C.A., Scherzinger, E., Wanker, E.E., Mangiarini, L. and Bates, G.P. (1997) Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell, 90, 537-548.
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
DiFiglia, M.4
Sharp, A.H.5
Ross, C.A.6
Scherzinger, E.7
Wanker, E.E.8
Mangiarini, L.9
Bates, G.P.10
-
13
-
-
0032811511
-
Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice
-
Li, H., Li, S.H., Cheng, A.L., Mangiarini, L., Bates, G.P. and Li, X.J. (1999) Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice. Hum. Mol. Genet., 8, 1227-1236.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 1227-1236
-
-
Li, H.1
Li, S.H.2
Cheng, A.L.3
Mangiarini, L.4
Bates, G.P.5
Li, X.J.6
-
14
-
-
0032475931
-
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
-
Saudou, F., Finkbeiner, S., Devys, D. and Greenberg, M.E. (1998) Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell, 95, 55-66.
-
(1998)
Cell
, vol.95
, pp. 55-66
-
-
Saudou, F.1
Finkbeiner, S.2
Devys, D.3
Greenberg, M.E.4
-
15
-
-
0032475941
-
Ataxin-1 nuclear localization and aggregation: Role in polyglutamine-induced disease in SCA1 transgenic mice
-
Klement, I.A., Skinner, P.J., Kaytor, M.D., Yi, H., Hersch, S.M., Clark, H.B., Zoghbi, H.Y. and Orr, H.T. (1998) Ataxin-1 nuclear localization and aggregation: Role in polyglutamine-induced disease in SCA1 transgenic mice. Cell, 95, 41-53.
-
(1998)
Cell
, vol.95
, pp. 41-53
-
-
Klement, I.A.1
Skinner, P.J.2
Kaytor, M.D.3
Yi, H.4
Hersch, S.M.5
Clark, H.B.6
Zoghbi, H.Y.7
Orr, H.T.8
-
16
-
-
18644379256
-
Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy
-
Katsuno, M., Adachi, H., Kume, A., Li, M., Nakagomi, Y., Niwa, H., Sang, C., Kobayashi, Y., Doyu, M. and Sobue, G. (2002) Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy. Neuron, 35, 843-854.
-
(2002)
Neuron
, vol.35
, pp. 843-854
-
-
Katsuno, M.1
Adachi, H.2
Kume, A.3
Li, M.4
Nakagomi, Y.5
Niwa, H.6
Sang, C.7
Kobayashi, Y.8
Doyu, M.9
Sobue, G.10
-
17
-
-
0038104366
-
Nucleocytoplasmic transport signals affect the age at onset of abnormalities in knock-in mice expressing polyglutamine within an ectopic protein context
-
Jackson, W.S., Tallaksen-Greene, S.J., Albin, R.L. and Detloff, P.J. (2003) Nucleocytoplasmic transport signals affect the age at onset of abnormalities in knock-in mice expressing polyglutamine within an ectopic protein context. Hum. Mol. Genet., 12, 1621-1629.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 1621-1629
-
-
Jackson, W.S.1
Tallaksen-Greene, S.J.2
Albin, R.L.3
Detloff, P.J.4
-
18
-
-
4344636957
-
Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice
-
Schilling, G., Savonenko, A.V., Klevytska, A., Morton, J.L., Tucker, S.M., Poirier, M., Gale, A., Chan, N., Gonzales, V., Slunt, H.H. et al. (2004) Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice. Hum. Mol. Genet., 13, 1599-1610.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 1599-1610
-
-
Schilling, G.1
Savonenko, A.V.2
Klevytska, A.3
Morton, J.L.4
Tucker, S.M.5
Poirier, M.6
Gale, A.7
Chan, N.8
Gonzales, V.9
Slunt, H.H.10
-
19
-
-
0021716406
-
A short amino acid sequence able to specify nuclear location
-
Kalderon, D., Roberts, B.L., Richardson, W.D. and Smith, A.E. (1984) A short amino acid sequence able to specify nuclear location. Cell, 39, 499-509.
-
(1984)
Cell
, vol.39
, pp. 499-509
-
-
Kalderon, D.1
Roberts, B.L.2
Richardson, W.D.3
Smith, A.E.4
-
20
-
-
0029786994
-
Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal
-
Fukuda, M., Gotoh, I., Gotoh, Y. and Nishida, E. (1996) Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal. J. Biol. Chem., 271, 20024-20028.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20024-20028
-
-
Fukuda, M.1
Gotoh, I.2
Gotoh, Y.3
Nishida, E.4
-
21
-
-
0031453047
-
A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase
-
Fukuda, M., Gotoh, I., Adachi, M., Gotoh, Y. and Nishida, E. (1997) A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase. J. Biol. Chem., 272, 32642-32648.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32642-32648
-
-
Fukuda, M.1
Gotoh, I.2
Adachi, M.3
Gotoh, Y.4
Nishida, E.5
-
22
-
-
0031255352
-
Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment
-
Rogers, D.C., Fisher, E.M., Brown, S.D., Peters, J., Hunter, A.J. and Martin, J.E. (1997) Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment. Mamm. Genome, 8, 711-713.
-
(1997)
Mamm. Genome
, vol.8
, pp. 711-713
-
-
Rogers, D.C.1
Fisher, E.M.2
Brown, S.D.3
Peters, J.4
Hunter, A.J.5
Martin, J.E.6
-
23
-
-
0034608857
-
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
-
Turmaine, M., Raza, A., Mahal, A., Mangiarini, L., Bates, G.P. and Davies, S.W. (2000) Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease. Proc. Natl Acad. Sci. USA, 97, 8093-8097.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 8093-8097
-
-
Turmaine, M.1
Raza, A.2
Mahal, A.3
Mangiarini, L.4
Bates, G.P.5
Davies, S.W.6
-
24
-
-
0037444445
-
Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease
-
Yu, Z.X., Li, S.H., Evans, J., Pillarisetti, A., Li, H. and Li, X.J. (2003) Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease. J. Neurosci., 23, 2193-2202.
-
(2003)
J. Neurosci.
, vol.23
, pp. 2193-2202
-
-
Yu, Z.X.1
Li, S.H.2
Evans, J.3
Pillarisetti, A.4
Li, H.5
Li, X.J.6
-
25
-
-
0141828353
-
Mechanisms of transcriptional dysregulation in Huntington's disease
-
Luthi-Carter, R. and Cha, J.-H.J. (2003) Mechanisms of transcriptional dysregulation in Huntington's disease. Clin. Neurosci. Res., 3, 165-177.
-
(2003)
Clin. Neurosci. Res.
, vol.3
, pp. 165-177
-
-
Luthi-Carter, R.1
Cha, J.-H.J.2
-
26
-
-
0037101835
-
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: Parallel changes in muscle and brain
-
Luthi-Carter, R., Hanson, S.A., Strand, A.D., Bergstrom, D.A., Chun, W., Peters, N.L., Woods, A.M., Chan, E.Y., Kooperberg, C., Krainc, D. et al. (2002) Dysregulation of gene expression in the R6/2 model of polyglutamine disease: Parallel changes in muscle and brain. Hum. Mol. Genet., 11, 1911-1926.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1911-1926
-
-
Luthi-Carter, R.1
Hanson, S.A.2
Strand, A.D.3
Bergstrom, D.A.4
Chun, W.5
Peters, N.L.6
Woods, A.M.7
Chan, E.Y.8
Kooperberg, C.9
Krainc, D.10
-
27
-
-
0037101837
-
Polyglutamine and transcription: Gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects
-
Luthi-Carter, R., Strand, A.D., Hanson, S.A., Kooperberg, C., Schilling, G., La Spada, A.R., Merry, D.E., Young, A.B., Ross, C.A., Borchelt, D.R. et al. (2002) Polyglutamine and transcription: Gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects. Hum. Mol. Genet., 11, 1927-1937.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1927-1937
-
-
Luthi-Carter, R.1
Strand, A.D.2
Hanson, S.A.3
Kooperberg, C.4
Schilling, G.5
La Spada, A.R.6
Merry, D.E.7
Young, A.B.8
Ross, C.A.9
Borchelt, D.R.10
-
28
-
-
0041353535
-
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
-
Zuccato, C., Tartari, M., Crotti, A., Goffredo, D., Valenza, M., Conti, L., Cataudella, T., Leavitt, B.R., Hayden, M.R., Timmusk, T. et al. (2003) Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nat. Genet., 35, 76-83.
-
(2003)
Nat. Genet.
, vol.35
, pp. 76-83
-
-
Zuccato, C.1
Tartari, M.2
Crotti, A.3
Goffredo, D.4
Valenza, M.5
Conti, L.6
Cataudella, T.7
Leavitt, B.R.8
Hayden, M.R.9
Timmusk, T.10
-
29
-
-
13944275615
-
Polyglutamine expansion of huntingtin impairs its nuclear export
-
Cornett, J., Cao, F., Wang, C.E., Ross, C.A., Bates, G.P., Li, S.H. and Li, X.J. (2005) Polyglutamine expansion of huntingtin impairs its nuclear export. Nat. Genet., 37, 198-204.
-
(2005)
Nat. Genet.
, vol.37
, pp. 198-204
-
-
Cornett, J.1
Cao, F.2
Wang, C.E.3
Ross, C.A.4
Bates, G.P.5
Li, S.H.6
Li, X.J.7
-
30
-
-
0034110465
-
Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila
-
Marsh, J.L., Walker, H., Theisen, H., Zhu, Y.Z., Fielder, T., Purcell, J. and Thompson, L.M. (2000) Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila. Hum. Mol. Genet., 9, 13-25.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 13-25
-
-
Marsh, J.L.1
Walker, H.2
Theisen, H.3
Zhu, Y.Z.4
Fielder, T.5
Purcell, J.6
Thompson, L.M.7
-
31
-
-
0038476184
-
Evidence for more widespread cerebral pathology in early HD: An MRI-based morphometric analysis
-
Rosas, H.D., Koroshetz, W.J., Chen, Y.I., Skeuse, C., Vangel, M., Cudkowicz, M.E., Caplan, K., Marek, K., Seidman, L.J., Makris, N. et al. (2003) Evidence for more widespread cerebral pathology in early HD: An MRI-based morphometric analysis. Neurology, 60, 1615-1620.
-
(2003)
Neurology
, vol.60
, pp. 1615-1620
-
-
Rosas, H.D.1
Koroshetz, W.J.2
Chen, Y.I.3
Skeuse, C.4
Vangel, M.5
Cudkowicz, M.E.6
Caplan, K.7
Marek, K.8
Seidman, L.J.9
Makris, N.10
-
32
-
-
4644245086
-
In vivo evidence of cerebellar atrophy and cerebral white matter loss in Huntington disease
-
Fennema-Notestine, C., Archibald, S.L., Jacobson, M.W., Corey-Bloom, J., Paulsen, J.S., Peavy, G.M., Gamst, A.C., Hamilton, J.M., Salmon, D.P. and Jernigan, T.L. (2004) In vivo evidence of cerebellar atrophy and cerebral white matter loss in Huntington disease. Neurology, 63, 989-995.
-
(2004)
Neurology
, vol.63
, pp. 989-995
-
-
Fennema-Notestine, C.1
Archibald, S.L.2
Jacobson, M.W.3
Corey-Bloom, J.4
Paulsen, J.S.5
Peavy, G.M.6
Gamst, A.C.7
Hamilton, J.M.8
Salmon, D.P.9
Jernigan, T.L.10
-
33
-
-
10744224530
-
Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport
-
Szebenyi, G., Morfini, G.A., Babcock, A., Gould, M., Selkoe, K., Stenoien, D.L., Young, M., Faber, P.W., MacDonald, M.E., McPhaul, M.J. et al. (2003) Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport. Neuron, 40, 41-52.
-
(2003)
Neuron
, vol.40
, pp. 41-52
-
-
Szebenyi, G.1
Morfini, G.A.2
Babcock, A.3
Gould, M.4
Selkoe, K.5
Stenoien, D.L.6
Young, M.7
Faber, P.W.8
MacDonald, M.E.9
McPhaul, M.J.10
-
34
-
-
0141750470
-
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila
-
Gunawardena, S., Her, L.S., Brusch, R.G., Laymon, R.A., Niesman, I.R., Gordesky-Gold, B., Sintasath, L., Bonini, N.M. and Goldstein, L.S. (2003) Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron, 40, 25-40.
-
(2003)
Neuron
, vol.40
, pp. 25-40
-
-
Gunawardena, S.1
Her, L.S.2
Brusch, R.G.3
Laymon, R.A.4
Niesman, I.R.5
Gordesky-Gold, B.6
Sintasath, L.7
Bonini, N.M.8
Goldstein, L.S.9
-
35
-
-
0034426013
-
Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity
-
Li, H., Li, S.H., Johnston, H., Shelbourne, P.F. and Li, X.J. (2000) Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity. Nat. Genet., 25, 385-389.
-
(2000)
Nat. Genet.
, vol.25
, pp. 385-389
-
-
Li, H.1
Li, S.H.2
Johnston, H.3
Shelbourne, P.F.4
Li, X.J.5
-
36
-
-
0042921188
-
Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release
-
Li, H., Wyman, T., Yu, Z.X., Li, S.H. and Li, X.J. (2003) Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release. Hum. Mol. Genet., 12, 2021-2030.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 2021-2030
-
-
Li, H.1
Wyman, T.2
Yu, Z.X.3
Li, S.H.4
Li, X.J.5
-
37
-
-
0036327065
-
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines
-
Panov, A.V., Gutekunst, C.A., Leavitt, B.R., Hayden, M.R., Burke, J.R., Strittmatter, W.J. and Greenamyre, J.T. (2002) Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines. Nat. Neurosci., 5, 731-736.
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 731-736
-
-
Panov, A.V.1
Gutekunst, C.A.2
Leavitt, B.R.3
Hayden, M.R.4
Burke, J.R.5
Strittmatter, W.J.6
Greenamyre, J.T.7
-
38
-
-
4444302167
-
Deranged neuronal calcium signaling and Huntington disease
-
Bezprozvanny, I. and Hayden, M.R. (2004) Deranged neuronal calcium signaling and Huntington disease. Biochem. Biophys. Res. Commun., 322, 1310-1317.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.322
, pp. 1310-1317
-
-
Bezprozvanny, I.1
Hayden, M.R.2
-
39
-
-
0141678246
-
Standardization and statistical approaches to therapeutic trials in the R6/2 mouse
-
Hockly, E., Woodman, B., Mahal, A., Lewis, C.M. and Bates, G. (2003) Standardization and statistical approaches to therapeutic trials in the R6/2 mouse. Brain. Res. Bull., 61, 469-479.
-
(2003)
Brain Res. Bull.
, vol.61
, pp. 469-479
-
-
Hockly, E.1
Woodman, B.2
Mahal, A.3
Lewis, C.M.4
Bates, G.5
-
40
-
-
0031056685
-
Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation
-
Mangiarini, L., Sathasivam, K., Mahal, A., Mott, R., Seller, M. and Bates, G.P. (1997) Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation. Nat. Genet., 15, 197-200.
-
(1997)
Nat. Genet.
, vol.15
, pp. 197-200
-
-
Mangiarini, L.1
Sathasivam, K.2
Mahal, A.3
Mott, R.4
Seller, M.5
Bates, G.P.6
-
41
-
-
4544333738
-
Neurotransmitter receptor analysis in transgenic mouse models
-
Benn, C.L., Farrell, L.A. and Cha, J.H. (2004) Neurotransmitter receptor analysis in transgenic mouse models. Methods Mol. Biol., 277, 231-260.
-
(2004)
Methods Mol. Biol.
, vol.277
, pp. 231-260
-
-
Benn, C.L.1
Farrell, L.A.2
Cha, J.H.3
-
42
-
-
0009762312
-
Preparation of nuclei and nuclear envelopes: Identification of an integral membrane protein unique to the nuclear envelope
-
Celis, J.E. (ed.), Academic Press, San Diego
-
Hallberg, E. (1994) Preparation of nuclei and nuclear envelopes: identification of an integral membrane protein unique to the nuclear envelope. In Celis, J.E. (ed.), Cell Biology: A Laboratory Handbook. Academic Press, San Diego. Vol. 1, pp. 613-627.
-
(1994)
Cell Biology: A Laboratory Handbook
, vol.1
, pp. 613-627
-
-
Hallberg, E.1
-
43
-
-
0035504960
-
Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients
-
Sathasivam, K., Woodman, B., Mahal, A., Bertaux, F., Wanker, E.E., Shima, D.T. and Bates, G.P. (2001) Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients. Hum. Mol. Genet., 10, 2425-2435.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 2425-2435
-
-
Sathasivam, K.1
Woodman, B.2
Mahal, A.3
Bertaux, F.4
Wanker, E.E.5
Shima, D.T.6
Bates, G.P.7
-
44
-
-
18544400323
-
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo
-
Scherzinger, E., Lurz, R., Turmaine, M., Mangiarini, L., Hollenbach, B., Hasenbank, R., Bates, G.P., Davies, S.W., Lehrach, H. and Wanker, E.E. (1997) Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo. Cell, 90, 549-558.
-
(1997)
Cell
, vol.90
, pp. 549-558
-
-
Scherzinger, E.1
Lurz, R.2
Turmaine, M.3
Mangiarini, L.4
Hollenbach, B.5
Hasenbank, R.6
Bates, G.P.7
Davies, S.W.8
Lehrach, H.9
Wanker, E.E.10
-
45
-
-
0035668573
-
Inhibition of polyglutamine aggregation in R6/2 HD brain slices-complex dose-response profiles
-
Smith, D.L., Portier, R., Woodman, B., Hockly, E., Mahal, A., Klunk, W.E., Li, X.J., Wanker, E., Murray, K.D. and Bates, G.P. (2001) Inhibition of polyglutamine aggregation in R6/2 HD brain slices-complex dose-response profiles. Neurobiol Dis., 8, 1017-1026.
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 1017-1026
-
-
Smith, D.L.1
Portier, R.2
Woodman, B.3
Hockly, E.4
Mahal, A.5
Klunk, W.E.6
Li, X.J.7
Wanker, E.8
Murray, K.D.9
Bates, G.P.10
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