Caspase-3 is required in the apoptotic disintegration of the nuclear matrix

Experimental Cell Research

Volumn 311, Issue 1, 2005, Pages 62-73

  Kivinen, Katri ^a,b   Kallajoki, Markku ^a   Taimen, Pekka ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

Apoptosis; Caspase inhibitor; Caspase 3; Lamins; Nuclear matrix; NuMA

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; LAMIN A; LAMIN B; LAMIN C; STAUROSPORINE;

APOPTOSIS; ARTICLE; CELL DESTRUCTION; CELL NUCLEUS; CELL NUCLEUS MATRIX; CELL STRAIN MCF 7; CHROMATIN CONDENSATION; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MITOSIS; NUCLEAR LAMINA; PRIORITY JOURNAL;

MINK CELL FOCUS-FORMING VIRUS;

EID: 27344454003     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2005.08.006     Document Type: Article

References (45)

1. J.F. Kerr, A.H. Wyllie, and A.R. Currie Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics Br. J. Cancer 26 1972 239 257
2. M.O. Hengartner The biochemistry of apoptosis Nature 407 2000 770 776
3. J. Nickerson Experimental observations of a nuclear matrix J. Cell Sci. 114 2001 463 474
4. J.A. Nickerson, B.J. Blencowe, and S. Penman The architectural organization of nuclear metabolism Int. Rev. Cytol. 162A 1995 67 123
5. E.G. Fey, and S. Penman Nuclear matrix proteins reflect cell type of origin in cultured human cells Proc. Natl. Acad. Sci. U. S. A. 85 1988 121 125
6. B.K. Lydersen, and D.E. Pettijohn Human-specific nuclear protein that associates with the polar region of the mitotic apparatus: distribution in a human/hamster hybrid cell Cell 22 1980 489 499
7. M. Kallajoki, K. Weber, and M. Osborn A 210 kDa nuclear matrix protein is a functional part of the mitotic spindle; a microinjection study using SPN monoclonal antibodies EMBO J. 10 1991 3351 3362
8. A. Merdes, K. Ramyar, J.D. Vechio, and D.W. Cleveland A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly Cell 87 1996 447 458
9. D.A. Compton, and D.W. Cleveland NuMA is required for the proper completion of mitosis J. Cell Biol. 120 1993 947 957
10. J. Harborth, J. Wang, C. Gueth-Hallonet, K. Weber, and M. Osborn Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice EMBO J. 18 1999 1689 1700
11. M.E. Luderus, J.L. den Blaauwen, O.J. de Smit, D.A. Compton, and R. van Driel Binding of matrix attachment regions to lamin polymers involves single-stranded regions and the minor groove Mol. Cell. Biol. 14 1994 6297 6305
12. J. Harborth, K. Weber, and M. Osborn GAS41, a highly conserved protein in eukaryotic nuclei, binds to NuMA J. Biol. Chem. 275 2000 31979 31985
13. S.N. Mattagajasingh, S.C. Huang, J.S. Hartenstein, M. Snyder, V.T. Marchesi, and E.J. Benz A nonerythroid isoform of protein 4.1R interacts with the nuclear mitotic apparatus (NuMA) protein J. Cell Biol. 145 1999 29 43
14. C. Gueth-Hallonet, K. Weber, and M. Osborn Cleavage of the nuclear matrix protein NuMA during apoptosis Exp. Cell Res. 233 1997 21 24
15. P. Taimen, and M. Kallajoki NuMA and nuclear lamins behave differently in Fas-mediated apoptosis J. Cell Sci. 116 2003 571 583
16. R. Bortul, M. Zweyer, A.M. Billi, G. Tabellini, R.L. Ochs, R. Bareggi, L. Cocco, and A.M. Martelli Nuclear changes in necrotic HL-60 cells J. Cell. Biochem. 81 2001 19 31
17. P. Taimen, H. Berghäll, R. Vainionpää, and M. Kallajoki NuMA and nuclear lamins are cleaved during viral infection-inhibition of caspase activity prevents cleavage and rescues HeLa cells from measles virus-induced but not from rhinovirus 1B-induced cell death Virology 320 2004 85 98
18. J. Harborth, S.M. Elbashir, K. Bechert, T. Tuschl, and K. Weber Identification of essential genes in cultured mammalian cells using small interfering RNAs J. Cell Sci. 114 2001 4557 4565
19. A. Merdes, and D.W. Cleveland The role of NuMA in the interphase nucleus J. Cell Sci. 111 1998 71 79
20. P. Taimen, M. Viljamaa, and M. Kallajoki Preferential expression of NuMA in the nuclei of proliferating cells Exp. Cell Res. 256 2000 140 149
21. P. Taimen, M. Parvinen, M. Osborn, and M. Kallajoki NuMA in rat testis-evidence for roles in proliferative activity and meiotic cell division Exp. Cell Res. 298 2004 512 520
22. M. Cohen, K.K. Lee, K.L. Wilson, and Y. Gruenbaum Transcriptional repression, apoptosis, human disease and the functional evolution of the nuclear lamina Trends Biochem. Sci. 26 2001 41 47
23. M.E. Luderus, A. de Graaf, E. Mattia, J.L. den Blaauwen, M.A. Grande, L. de Jong, and R. van Driel Binding of matrix attachment regions to lamin B1 Cell 70 1992 949 959
24. A. Takahashi, E.S. Alnemri, Y.A. Lazebnik, T. Fernandes-Alnemri, G. Litwack, R.D. Moir, R.D. Goldman, G.G. Poirier, S.H. Kaufmann, and W.C. Earnshaw Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis Proc. Natl. Acad. Sci. U. S. A. 93 1996 8395 8400
25. L. Rao, D. Perez, and E. White Lamin proteolysis facilitates nuclear events during apoptosis J. Cell Biol. 135 1996 1441 1455
26. S. Ruchaud, N. Korfali, P. Villa, T.J. Kottke, C. Dingwall, S.H. Kaufmann, and W.C. Earnshaw Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation EMBO J. 21 2002 1967 1977
27. E.A. Slee, C. Adrain, and S.J. Martin Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis J. Biol. Chem. 276 2001 7320 7326
28. X.H. Yang, T.L. Sladek, X. Liu, B.R. Butler, C.J. Froelich, and A.D. Thor Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis Cancer Res. 61 2001 348 354
29. R.U. Janicke, M.L. Sprengart, M.R. Wati, and A.G. Porter Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis J. Biol. Chem. 273 1998 9357 9360
30. V.L. Johnson, S.C. Ko, T.H. Holmstrom, J.E. Eriksson, and S.C. Chow Effector caspases are dispensable for the early nuclear morphological changes during chemical-induced apoptosis J. Cell Sci. 113 2000 2941 2953
31. M. Tewari, L.T. Quan, K. O'Rourke, S. Desnoyers, Z. Zeng, D.R. Beidler, G.G. Poirier, G.S. Salvesen, and V.M. Dixit Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase Cell 81 1995 801 809
32. M. Enari, H. Sakahira, H. Yokoyama, K. Okawa, A. Iwamatsu, and S. Nagata A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD Nature 391 1998 43 50
33. T.K. Tang, C.J. Tang, Y.L. Chen, and C.W. Wu Nuclear proteins of the bovine esophageal epithelium: II. The NuMA gene gives rise to multiple mRNAs and gene products reactive with monoclonal antibody W1 J. Cell Sci. 104 1993 249 260
34. S. Nagata, H. Nagase, K. Kawane, N. Mukae, and H. Fukuyama Degradation of chromosomal DNA during apoptosis Cell Death Differ. 10 2003 108 116
35. L.Y. Xue, S.M. Chiu, and N.L. Oleinick Staurosporine-induced death of MCF-7 human breast cancer cells: a distinction between caspase-3-dependent steps of apoptosis and the critical lethal lesions Exp. Cell Res. 283 2003 135 145
36. S.A. Susin, H.K. Lorenzo, N. Zamzami, I. Marzo, B.E. Snow, G.M. Brothers, J. Mangion, E. Jacotot, P. Costantini, M. Loeffler, N. Larochette, D.R. Goodlett, R. Aebersold, D.P. Siderovski, J.M. Penninger, and G. Kroemer Molecular characterization of mitochondrial apoptosis-inducing factor Nature 397 1999 441 446
37. L.Y. Li, X. Luo, and X. Wang Endonuclease G is an apoptotic DNase when released from mitochondria Nature 412 2001 95 99
38. M. Leist, and M. Jäättelä Four deaths and a funeral: from caspases to alternative mechanisms Nat. Rev., Mol. Cell Biol. 2 2001 589 598
39. M. Germain, E.B. Affar, D. D'Amours, V.M. Dixit, G.S. Salvesen, and G.G. Poirier Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7 J. Biol. Chem. 274 1999 28379 28384
40. N. Korfali, S. Ruchaud, D. Loegering, D. Bernard, C. Dingwall, S.H. Kaufmann, and W.C. Earnshaw Caspase-7 gene disruption reveals an involvement of the enzyme during the early stages of apoptosis J. Biol. Chem. 279 2004 1030 1039
41. M. Peter, J. Nakagawa, M. Doree, J.C. Labbe, and E.A. Nigg In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase Cell 61 1990 591 602
42. T. Cross, G. Griffiths, E. Deacon, R. Sallis, M. Gough, D. Watters, and J.M. Lord PKC-delta is an apoptotic lamin kinase Oncogene 19 2000 2331 2337
43. H. Hirata, A. Takahashi, S. Kobayashi, S. Yonehara, H. Sawai, T. Okazaki, K. Yamamoto, and M. Sasada Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis J. Exp. Med. 187 1998 587 600
44. L.A. Allan, N. Morrice, S. Brady, G. Magee, S. Pathak, and P.R. Clarke Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK Nat. Cell Biol. 5 2003 647 654
45. V.S. Marsden, L. O'Connor, L.A. O'Reilly, J. Silke, D. Metcalf, P.G. Ekert, D.C. Huang, F. Cecconi, K. Kuida, K.J. Tomaselli, S. Roy, D.W. Nicholson, D.L. Vaux, P. Bouillet, J.M. Adams, and A. Strasser Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome Nature 419 2002 634 637