Modulation of MPP+ uptake by tea and some of its components in Caco-2 cells

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 372, Issue 2, 2005, Pages 147-152

  Monteiro, R ^a,b   Calhau, C ^a   Martel, F ^a   Faria, A ^b   Mateus, N ^b   Azevedo, I ^a  

^a University of Porto   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Flavonoids; Intestinal transport; Organic cations; Tea; Xanthines

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; CAFFEINE; CATION; EPIGALLOCATECHIN GALLATE; MYRICETIN; THEOPHYLLINE; TRITIUM;

ABSORPTION; ARTICLE; CATION TRANSPORT; CELL STRAIN CACO 2; COMPARATIVE STUDY; CONTROLLED STUDY; FOOD DRUG INTERACTION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; ISOTOPE LABELING; MOLECULE; SUPPLEMENTATION; TEA;

1-METHYL-4-PHENYLPYRIDINIUM; CACO-2 CELLS; CAFFEINE; CATECHIN; CORTICOSTERONE; FOOD-DRUG INTERACTIONS; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; ORGANIC CATION TRANSPORT PROTEINS; PLANT EXTRACTS; QUINOLINES; TEA; THEOPHYLLINE; TRITIUM;

EID: 27144527244     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-005-0012-7     Document Type: Article

References (39)

1. Artursson P (1991) Cell cultures as models for drug absorption across the intestinal mucosa. Crit Rev Ther Drug Carrier Syst 8:305-330
2. Artursson P, Karlsson J (1991) Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal (Caco-2) cells. Biochem Biophys Res Commun 175:880-885
3. Auger C, Al-Awwadi N, Bornet A, Rouanet J, Gasc F, Cros G, Teissedre F (2004) Catechins and procyanidins in Mediterranean diets. Food Res Int 37:233-245
4. Bergmeyer HU, Bernt E (1974) Lactate dehydrogenase. In: Bergmeyer HU (ed) Methods in enzymatic analysis. Academic, New York, pp 574-579
5. Bradford MM (1976) A rapid method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
6. Ciarimboli G, Schlatter E (2005) Regulation of organic cation transport. Pflügers Arch 449:423-441
7. Darné G, Madero-Tamargo J (1979) Mise au point d'une méthode d'extraction des lipides solubles totaux, des glucides solubles totaux et des composés phénoliques solubles totaux des organes de la vigne. Vitis 18:221-228
8. Deferme S, Augustijns P (2003) The effect of food components on the absorption of P-gp substrates: a review. J Pharm Pharmacol 55:153-162
9. Delie F, Rubas W (1997) A human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: advantages and limitations of the Caco-2 model. Crit Rev Ther Drug Carrier Syst 14:221-286
10. de Pascual-Teresa S, Santos-Buelga C, Rivas-Gonzalo JC (2000) Quantitative analysis of flavan-3-ols in Spanish foodstuffs and beverages. J Agric Food Chem 48:5331-5337
11. Gründemann D, Schechinger B, Rappold GA, Schömig E (1998) Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter. Nat Neurosci 1:349-351
12. Gründemann D, Liebich G, Kiefe N, Köster S, Schömig E (1999) Selective substracts for non-neuronal monoamine transporters. Mol Pharmacol 56:1-10
13. Harris RZ, Jang GR, Tsunoda S (2003) Dietary effects on drug metabolism and transport. Clin Pharmacokinet 42:1071-1088
14. Hidalgo IJ, Raub TJ, Borchardt RT (1989) Characterisation of the human colonic carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology 96:736-749
15. + in mouse brain. Neurosci Lett 101:83-88
16. Jodoin J, Demeule M, Beliveau R (2002) Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols. Biochim Biophys Acta 1542:149-159
17. Kekuda R, Prasad PD, Wu X, Wang H, Fei YJ, Leibach FH, Ganapathy V (1998) Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta. J Biol Chem 273:15971-15979
18. Koepsell H (2004) Polyspecific organic cation transporters: their functions and interactions with drugs. Trends Pharmacol Sci 25:375-381
19. Kuruto-Niwa R, Inoue S, Ogawa S, Muramatsu M, Nozawa R (2000) Effects of tea catechins on the ERE-regulated estrogenic activity. J Agric Food Chem 48:6355-6361
20. Lee VH (2000) Membrane transporters. Eur J Pharm Sci 11 [Suppl 2]:S41-S50
21. Lennernas H (1997) Human jejunal effective permeability and its correlation with preclinical drug absorption models. J Pharm Pharmacol 49:627-638
22. Lu YP, Lou YR, Lin Y, Shih WJ, Huang MT, Yang CS, Conney AH (2001) Inhibitory effects of orally administered green tea, black tea, and caffeine on skin carcinogenesis in mice previously treated with ultraviolet B light (high-risk mice): relationship to decreased tissue fat. Cancer Res 61:5002-5009
23. Lung HL, Ip WK, Wong CK, Mak NK, Chen ZY, Leung KN (2002) Anti-proliferative and differentiation-inducing activities of the green tea catechin epigallocatechin-3-gallate (EGCG) on the human eosinophilic leukemia EoL-1 cell line. Life Sci 72:257-268
24. + in human intestinal epithelial (Caco-2) cells. Naunyn-Schmiedebergs Arch Pharmacol 361:505-513
25. Martel F, Gründemann D, Calhau C, Schömig E (2001) Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters. Naunyn-Schmiedebergs Arch Pharmacol 363:40-49
26. Melamed E, Rosenthal J, Cohen O, Globus M, Uzzan A (1985) Dopamine but not norepinephrine or serotonin uptake inhibitors protect mice against neurotoxicity of MPTP. Eur J Pharmacol 116:179-181
27. Michaud J, Lacaze P, Masquelier J (1971) Fractionnement des oligomères flavanoliques du raisin. Bull Soc Phar Bordeaux 110:111-116
28. + is differently affected by red and white wine. Life Sci 75:2483-2496
29. Mukhtar H, Ahmad N (2000) Tea polyphenols: prevention of cancer and optimizing health. Am J Clin Nutr 71(6 Suppl):1698S-1702S
30. Paquay JB, Haenen GR, Stender G, Wiseman SA, Tijburg LB, Bast A (2000) Protection against nitric oxide toxicity by tea. J Agric Food Chem 48:5768-5772
31. Sayre LM (1989) Biochemical mechanism of action of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Toxicol Lett 48:121-149
32. Trevisanato SI, Kim YI (2000) Tea and health. Nutr Rev 58:1-10
33. Wagner D, Spahn-Langguth H, Hanafy A, Koggel A, Langguth P (2001) Intestinal drug efflux: formulation and food effects. Adv Drug Deliv Rev 50 [Suppl 1]:S13-S31
34. Yang CS, Landau JM (2000) Effects of tea consumption on nutrition and health. J Nutr 130:2409-2412
35. Yang CS, Chung JY, Yang G, Chhabra SK, Lee MJ (2000) Tea and tea polyphenols in cancer prevention. J Nutr 130[2S Suppl]:472S-478S
36. Yang CS, Maliakal P, Meng X (2002) Inhibition of carcinogenesis by tea. Annu Rev Pharmacol Toxicol 42:25-54
37. Yee S (1997) In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man - fact or myth. Pharmacol Res 14:763-766
38. Zhang L, Brett CM, Giacomini KM (1998) Role of organic cation transporters in drug absorption and elimination. Annu Rev Pharmacol Toxicol 38:431-460
39. Zhang M, Binns CW, Lee AH (2002) Tea consumption and ovarian cancer risk: a case-control study in China. Cancer Epidemiol Biomarkers Prev 11:713-718