-
1
-
-
0013394889
-
Mechanisms of alternative pre-messenger RNA splicing
-
Black DL: Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem (2003) 72:291-336.
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 291-336
-
-
Black, D.L.1
-
2
-
-
0036534129
-
Alternative splicing: Multiple control mechanisms and involvement in human disease
-
Caceres JF, Kornblihtt AR: Alternative splicing: Multiple control mechanisms and involvement in human disease. Trends Genet (2002) 18(4):186-193.
-
(2002)
Trends Genet.
, vol.18
, Issue.4
, pp. 186-193
-
-
Caceres, J.F.1
Kornblihtt, A.R.2
-
3
-
-
0036207384
-
Listening to silence and understanding nonsense: Exonic mutations that affect splicing
-
Cartegni L, Chew SL, Krainer AR: Listening to silence and understanding nonsense: Exonic mutations that affect splicing. Nat Rev Genet (2002) 3(4):285-298.
-
(2002)
Nat. Rev. Genet.
, vol.3
, Issue.4
, pp. 285-298
-
-
Cartegni, L.1
Chew, S.L.2
Krainer, A.R.3
-
4
-
-
0037443035
-
Pre-mRNA splicing and human disease
-
Faustino NA, Cooper TA: Pre-mRNA splicing and human disease. Genes Dev (2003) 17(4):419-437.
-
(2003)
Genes Dev.
, vol.17
, Issue.4
, pp. 419-437
-
-
Faustino, N.A.1
Cooper, T.A.2
-
5
-
-
0037678415
-
Cell-specific RNA-binding proteins in human disease
-
Musunuru K: Cell-specific RNA-binding proteins in human disease. Trends Cardiovasc Med (2003) 13(5):188-195.
-
(2003)
Trends Cardiovasc. Med.
, vol.13
, Issue.5
, pp. 188-195
-
-
Musunuru, K.1
-
6
-
-
0344011094
-
Intrinsic differences between authentic and cryptic 5′ splice sites
-
Roca X, Sachidanandam R, Krainer AR: Intrinsic differences between authentic and cryptic 5′ splice sites. Nucleic Acids Res (2003) 31(21):6321-6333.
-
(2003)
Nucleic Acids Res.
, vol.31
, Issue.21
, pp. 6321-6333
-
-
Roca, X.1
Sachidanandam, R.2
Krainer, A.R.3
-
8
-
-
0038617729
-
Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss
-
Modrek B, Lee CJ: Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss. Nat Genet (2003) 34(2):177-180.
-
(2003)
Nat. Genet.
, vol.34
, Issue.2
, pp. 177-180
-
-
Modrek, B.1
Lee, C.J.2
-
9
-
-
0347623371
-
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays
-
Johnson JM, Castle J, Garrett-Engele P, Kan Z, Loerch PM, Armour CD, Santos R, Schadt EE, Stoughton R, Shoemaker DD: Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Science (2003) 302(5653):2141-2144.
-
(2003)
Science
, vol.302
, Issue.5653
, pp. 2141-2144
-
-
Johnson, J.M.1
Castle, J.2
Garrett-Engele, P.3
Kan, Z.4
Loerch, P.M.5
Armour, C.D.6
Santos, R.7
Schadt, E.E.8
Stoughton, R.9
Shoemaker, D.D.10
-
10
-
-
1642473041
-
How prevalent is functional alternative splicing in the human genome?
-
Sorek R, Shamir R, Ast G: How prevalent is functional alternative splicing in the human genome? Trends Genet (2004) 20(2):68-71.
-
(2004)
Trends Genet.
, vol.20
, Issue.2
, pp. 68-71
-
-
Sorek, R.1
Shamir, R.2
Ast, G.3
-
11
-
-
2542603045
-
Evidence for a subpopulation of conserved alternative splicing events under selection pressure for protein reading frame preservation
-
Resch A, Xing Y, Alekseyenko A, Modrek B, Lee C: Evidence for a subpopulation of conserved alternative splicing events under selection pressure for protein reading frame preservation. Nucleic Acids Res (2004) 32(4):1261-1269.
-
(2004)
Nucleic Acids Res.
, vol.32
, Issue.4
, pp. 1261-1269
-
-
Resch, A.1
Xing, Y.2
Alekseyenko, A.3
Modrek, B.4
Lee, C.5
-
12
-
-
27144556381
-
-
Human Gene Mutation Database. HGMD, Cardiff, UK January 19
-
Human Gene Mutation Database. HGMD, Cardiff, UK (2005): January 19. http://www.hgmd.org/
-
(2005)
-
-
-
13
-
-
0037897328
-
Disruption of exon definition produces a dominant-negative growth hormone isoform that causes somatotroph death and IGHD II
-
Ryther RC, McGuinness LM, Phillips JA 3rd, Moseley CT, Magoulas CB, Robinson IC, Patton JG: Disruption of exon definition produces a dominant-negative growth hormone isoform that causes somatotroph death and IGHD II. Hum Genet (2003) 113(2):140-148.
-
(2003)
Hum. Genet.
, vol.113
, Issue.2
, pp. 140-148
-
-
Ryther, R.C.1
McGuinness, L.M.2
Phillips III, J.A.3
Moseley, C.T.4
Magoulas, C.B.5
Robinson, I.C.6
Patton, J.G.7
-
14
-
-
0037243203
-
Novel mutations of the growth hormone 1 (GH1) gene disclosed by modulation of the clinical selection criteria for individuals with short stature
-
Millar DS, Lewis MD, Horan M, Newsway V, Easter TE, Gregory JW, Fryklund L, Norin M, Crowne EC, Davies SJ, Edwards P et al: Novel mutations of the growth hormone 1 (GH1) gene disclosed by modulation of the clinical selection criteria for individuals with short stature. Hum Mutat (2003) 21(4):424-440.
-
(2003)
Hum. Mutat.
, vol.21
, Issue.4
, pp. 424-440
-
-
Millar, D.S.1
Lewis, M.D.2
Horan, M.3
Newsway, V.4
Easter, T.E.5
Gregory, J.W.6
Fryklund, L.7
Norin, M.8
Crowne, E.C.9
Davies, S.J.10
Edwards, P.11
-
15
-
-
0029004293
-
Are CD44 variant isoforms involved in human tumour progression?
-
Gunthert U, Stauder R, Mayer B, Terpe HJ, Finke L, Friedrichs K: Are CD44 variant isoforms involved in human tumour progression? Cancer Surv (1995) 24:19-42.
-
(1995)
Cancer Surv.
, vol.24
, pp. 19-42
-
-
Gunthert, U.1
Stauder, R.2
Mayer, B.3
Terpe, H.J.4
Finke, L.5
Friedrichs, K.6
-
16
-
-
7444220147
-
Aberrant and alternative splicing in cancer
-
Venables JP: Aberrant and alternative splicing in cancer. Cancer Res (2004) 64(21):7647-7654.
-
(2004)
Cancer Res.
, vol.64
, Issue.21
, pp. 7647-7654
-
-
Venables, J.P.1
-
17
-
-
0037101633
-
Ischemia induces a translocation of the splicing factor tra2-β1 and changes alternative splicing patterns in the brain
-
Daoud R, Mies G, Smialowska A, Olah L, Hossmann KA, Stamm S: Ischemia induces a translocation of the splicing factor tra2-β1 and changes alternative splicing patterns in the brain. J Neurosci (2002) 22(14):5889-5899.
-
(2002)
J. Neurosci.
, vol.22
, Issue.14
, pp. 5889-5899
-
-
Daoud, R.1
Mies, G.2
Smialowska, A.3
Olah, L.4
Hossmann, K.A.5
Stamm, S.6
-
18
-
-
0027198248
-
Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy
-
Yan G, Fukabori Y, McBride G, Nikolaropolous S, McKeehan WL: Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy. Mol Cell Biol (1993) 13(8):4513-4522.
-
(1993)
Mol. Cell Biol.
, vol.13
, Issue.8
, pp. 4513-4522
-
-
Yan, G.1
Fukabori, Y.2
McBride, G.3
Nikolaropolous, S.4
McKeehan, W.L.5
-
19
-
-
0031577732
-
Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancer
-
Carstens RP, Eaton JV, Krigman HR, Walther PJ, Garcia-Blanco MA: Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancer. Oncogene (1997) 15(25):3059-3065.
-
(1997)
Oncogene
, vol.15
, Issue.25
, pp. 3059-3065
-
-
Carstens, R.P.1
Eaton, J.V.2
Krigman, H.R.3
Walther, P.J.4
Garcia-Blanco, M.A.5
-
20
-
-
5344273996
-
Restoration of fibroblast growth factor receptor 2 suppresses growth and tumorigenicity of malignant human prostate carcinoma PC-3 cells
-
Yasumoto H, Matsubara A, Mutaguchi K, Usui T, McKeehan WL: Restoration of fibroblast growth factor receptor 2 suppresses growth and tumorigenicity of malignant human prostate carcinoma PC-3 cells. Prostate (2004) 61(3):236-242.
-
(2004)
Prostate
, vol.61
, Issue.3
, pp. 236-242
-
-
Yasumoto, H.1
Matsubara, A.2
Mutaguchi, K.3
Usui, T.4
McKeehan, W.L.5
-
21
-
-
0142134358
-
The relevance of alternative RNA splicing to pharmacogenomics
-
Bracco L, Kearsey J: The relevance of alternative RNA splicing to pharmacogenomics. Trends Biotechnol (2003) 21(8):346-353.
-
(2003)
Trends Biotechnol.
, vol.21
, Issue.8
, pp. 346-353
-
-
Bracco, L.1
Kearsey, J.2
-
22
-
-
0037108979
-
COX-3, a cyclooxygenase-II variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression
-
Chandrasekharan NV, Dai H, Roos KL, Evanson NK, Tomsik J, Elton TS, Simmons DL: COX-3, a cyclooxygenase-II variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression. Proc Natl Acad Sci USA (2002) 99(21):13926-13931.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.21
, pp. 13926-13931
-
-
Chandrasekharan, N.V.1
Dai, H.2
Roos, K.L.3
Evanson, N.K.4
Tomsik, J.5
Elton, T.S.6
Simmons, D.L.7
-
23
-
-
0142258064
-
Variants of cyclooxygenass-1 and their roles in medicine
-
Simmons DL: Variants of cyclooxygenass-1 and their roles in medicine. Thromb Res (2003) 110(5-6):265-268.
-
(2003)
Thromb. Res.
, vol.110
, Issue.5-6
, pp. 265-268
-
-
Simmons, D.L.1
-
24
-
-
0141834020
-
Evidence for a modifying pathway in SMA discordant families: Reduced SMN level decreases the amount of its interacting partners and Htra2-β1
-
Helmken C, Hofmann Y, Schoenen F, Oprea G, Raschke H, Rudnik-Schoneborn S, Zerres K, Wirth B: Evidence for a modifying pathway in SMA discordant families: Reduced SMN level decreases the amount of its interacting partners and Htra2-β1. Hum Genet (2003) 114(1):11-21.
-
(2003)
Hum. Genet.
, vol.114
, Issue.1
, pp. 11-21
-
-
Helmken, C.1
Hofmann, Y.2
Schoenen, F.3
Oprea, G.4
Raschke, H.5
Rudnik-Schoneborn, S.6
Zerres, K.7
Wirth, B.8
-
25
-
-
0033033434
-
A single nuclootide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy
-
Lorson CL, Hahnen E, Androphy EJ, Wirth B: A single nuclootide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy. Proc Natl Acad Sci USA (1999) 96(11):6307-6311.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, Issue.11
, pp. 6307-6311
-
-
Lorson, C.L.1
Hahnen, E.2
Androphy, E.J.3
Wirth, B.4
-
26
-
-
0041665176
-
A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy
-
Kashima T, Manley JL: A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy. Nat Genet (2003) 34(4):460-463.
-
(2003)
Nat. Genet.
, vol.34
, Issue.4
, pp. 460-463
-
-
Kashima, T.1
Manley, J.L.2
-
27
-
-
0842289003
-
An extended inhibitory context causes skipping of exon 7 of SMN2 in spinal muscular atrophy
-
Singh NN, Androphy EJ, Singh RN: An extended inhibitory context causes skipping of exon 7 of SMN2 in spinal muscular atrophy. Biochem Biophys Res Commun (2004) 316(2):381-388.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.316
, Issue.2
, pp. 381-388
-
-
Singh, N.N.1
Androphy, E.J.2
Singh, R.N.3
-
28
-
-
0034327218
-
Interferons and IRF-1 induce expression of the survival motor neuron (SMN) genes
-
Baron-Delage S, Abadie A, Echaniz-Laguna A, Melki J, Beretta L: Interferons and IRF-1 induce expression of the survival motor neuron (SMN) genes. Mol Med (2000) 6(11):957-968.
-
(2000)
Mol. Med.
, vol.6
, Issue.11
, pp. 957-968
-
-
Baron-Delage, S.1
Abadie, A.2
Echaniz-Laguna, A.3
Melki, J.4
Beretta, L.5
-
29
-
-
0141506887
-
Valproic acid increases the SMN2 protein level: A well-known drug as a potential therapy for spinal muscular atrophy
-
Brichta L, Hofmann Y, Hahnen E, Siebzehnrubl FA, Raschke H, Blumcke I, Eyupoglu IY, Wirth B: Valproic acid increases the SMN2 protein level: A well-known drug as a potential therapy for spinal muscular atrophy. Hum Mol Genet (2003) 12(19):2481-2489.
-
(2003)
Hum. Mol. Genet.
, vol.12
, Issue.19
, pp. 2481-2489
-
-
Brichta, L.1
Hofmann, Y.2
Hahnen, E.3
Siebzehnrubl, F.A.4
Raschke, H.5
Blumcke, I.6
Eyupoglu, I.Y.7
Wirth, B.8
-
30
-
-
0035859952
-
Treatment of spinal muscular atrophy by sodium butyrate
-
Chang JG, Hsieh-Li HM, Jong YJ, Wang NM, Tsai CH, Li H: Treatment of spinal muscular atrophy by sodium butyrate. Proc Natl Acad Sci USA (2001) 98(17):9808-9813.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.17
, pp. 9808-9813
-
-
Chang, J.G.1
Hsieh-Li, H.M.2
Jong, Y.J.3
Wang, N.M.4
Tsai, C.H.5
Li, H.6
-
32
-
-
0035891862
-
Aclarubicin treatment restores SMN levels to cells derived from type I spinal muscular atrophy patients
-
Andreassi C, Jarecki J, Zhou J, Coovert DD, Monani UR, Chen X, Whitney M, Pollok B, Zhang M, Androphy E, Burghes AH: Aclarubicin treatment restores SMN levels to cells derived from type I spinal muscular atrophy patients. Hum Mol Genet (2001) 10(24):2841-2849.
-
(2001)
Hum. Mol. Genet.
, vol.10
, Issue.24
, pp. 2841-2849
-
-
Andreassi, C.1
Jarecki, J.2
Zhou, J.3
Coovert, D.D.4
Monani, U.R.5
Chen, X.6
Whitney, M.7
Pollok, B.8
Zhang, M.9
Androphy, E.10
Burghes, A.H.11
-
33
-
-
3242719541
-
Antisense strategies
-
Crooke ST: Antisense strategies. Curr Mol Med (2004) 4(5):465-487.
-
(2004)
Curr. Mol. Med.
, vol.4
, Issue.5
, pp. 465-487
-
-
Crooke, S.T.1
-
34
-
-
1542269161
-
Progress in antisense technology
-
Crooke ST: Progress in antisense technology. Annu Rev Med (2004) 55:61-95.
-
(2004)
Annu. Rev. Med.
, vol.55
, pp. 61-95
-
-
Crooke, S.T.1
-
35
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
-
Zamecnik PC, Stephenson ML: Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc Natl Acad Sci USA (1978) 75(1):280-284.
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, Issue.1
, pp. 280-284
-
-
Zamecnik, P.C.1
Stephenson, M.L.2
-
36
-
-
0005772676
-
Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide
-
Stephenson ML, Zamecnik PC: Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc Natl Acad Sci USA (1978) 75(1):285-288.
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, Issue.1
, pp. 285-288
-
-
Stephenson, M.L.1
Zamecnik, P.C.2
-
37
-
-
0036202668
-
A randomized controlled clinical trial of intravitreous fomivirsen for treatment of newly diagnosed peripheral cytomegalovirus retinitis in patients with AIDS
-
Vitravene Study Group
-
Vitravene Study Group: A randomized controlled clinical trial of intravitreous fomivirsen for treatment of newly diagnosed peripheral cytomegalovirus retinitis in patients with AIDS. Am J Ophthalmol (2002) 133(4):467-474.
-
(2002)
Am. J. Ophthalmol.
, vol.133
, Issue.4
, pp. 467-474
-
-
-
38
-
-
0027284424
-
Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides
-
Dominski Z, Kole R: Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides. Proc Natl Acad Sci USA (1993) 90(18):8673-8677.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, Issue.18
, pp. 8673-8677
-
-
Dominski, Z.1
Kole, R.2
-
39
-
-
0029803547
-
Repair of thalassemic human β-globin mRNA in mammalian cells by antisense oligonucleotides
-
Sierakowska H, Sambade MJ, Agrawal S, Kole R: Repair of thalassemic human β-globin mRNA in mammalian cells by antisense oligonucleotides. Proc Natl Acad Sci USA (1996) 93(23):12840-12844.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, Issue.23
, pp. 12840-12844
-
-
Sierakowska, H.1
Sambade, M.J.2
Agrawal, S.3
Kole, R.4
-
40
-
-
24144502840
-
Effects of base modifications on antisense properties of 2′-O-methoxyethyl and PNA oligonucleotides
-
Sazani P, Astriab-Fischer A, Kole R: Effects of base modifications on antisense properties of 2′-O-methoxyethyl and PNA oligonucleotides. Antisense Nucleic Acid Drug Dev (2003) 13(3):119-128.
-
(2003)
Antisense Nucleic Acid Drug Dev.
, vol.13
, Issue.3
, pp. 119-128
-
-
Sazani, P.1
Astriab-Fischer, A.2
Kole, R.3
-
41
-
-
1942453441
-
Modification of alternative splicing by antisense therapeutics
-
Kole R, Vacek M, Williams T: Modification of alternative splicing by antisense therapeutics. Oligonucleotides (2004) 14(1):65-74.
-
(2004)
Oligonucleotides
, vol.14
, Issue.1
, pp. 65-74
-
-
Kole, R.1
Vacek, M.2
Williams, T.3
-
42
-
-
3242749727
-
RNA modulation, repair and remodeling by splice switching oligonucleotides
-
Kole R, Williams T, Cohen L: RNA modulation, repair and remodeling by splice switching oligonucleotides. Acta Biochim Pol (2004) 51(2):373-378.
-
(2004)
Acta Biochim. Pol.
, vol.51
, Issue.2
, pp. 373-378
-
-
Kole, R.1
Williams, T.2
Cohen, L.3
-
43
-
-
0034662881
-
Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients
-
Lacerra G, Sierakowska H, Carestia C, Fucharoen S, Summerton J, Weller D, Kole R: Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients. Proc Natl Acad Sci USA (2000) 97(17):9591-9596.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, Issue.17
, pp. 9591-9596
-
-
Lacerra, G.1
Sierakowska, H.2
Carestia, C.3
Fucharoen, S.4
Summerton, J.5
Weller, D.6
Kole, R.7
-
44
-
-
0038614842
-
Antisense-mediated redirection of mRNA splicing
-
Vacek M, Sazani P, Kole R: Antisense-mediated redirection of mRNA splicing. Cell Mol Life Sci (2003) 60(5):825-833.
-
(2003)
Cell Mol. Life Sci.
, vol.60
, Issue.5
, pp. 825-833
-
-
Vacek, M.1
Sazani, P.2
Kole, R.3
-
45
-
-
0032574744
-
Stable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAs
-
Gorman L, Suter D, Emerick V, Schumperli D, Kole R: Stable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAs. Proc Natl Acad Sci USA (1998) 95(9):4929-4934.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.9
, pp. 4929-4934
-
-
Gorman, L.1
Suter, D.2
Emerick, V.3
Schumperli, D.4
Kole, R.5
-
46
-
-
0033579478
-
Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides
-
Friedman KJ, Kole J, Cohn JA, Knowles MR, Silverman LM, Kole R: Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides. J Biol Chem (1999) 274(51):36193-36199.
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.51
, pp. 36193-36199
-
-
Friedman, K.J.1
Kole, J.2
Cohn, J.A.3
Knowles, M.R.4
Silverman, L.M.5
Kole, R.6
-
47
-
-
0030582315
-
Induction of exon skipping of the dystrophin transcript in lymphoblastoid cells by transfecting an antisense oligodeoxynucleotide complementary to an exon recognition sequence
-
Pramono ZA, Takeshima Y, Alimsardjono H, Ishii A, Takeda S, Matsuo M: Induction of exon skipping of the dystrophin transcript in lymphoblastoid cells by transfecting an antisense oligodeoxynucleotide complementary to an exon recognition sequence. Biochem Biophys Res Commun (1996) 226(2):445-449.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.226
, Issue.2
, pp. 445-449
-
-
Pramono, Z.A.1
Takeshima, Y.2
Alimsardjono, H.3
Ishii, A.4
Takeda, S.5
Matsuo, M.6
-
48
-
-
0031800293
-
Modification of splicing in the dystrophin gene in cultured mdx muscle cells by antisense oligoribonucleotides
-
Dunckley MG, Manoharan M, Villiet P, Eperon IC, Dickson G: Modification of splicing in the dystrophin gene in cultured mdx muscle cells by antisense oligoribonucleotides. Hum Mol Genet (1998) 7(7):1083-1090.
-
(1998)
Hum. Mol. Genet.
, vol.7
, Issue.7
, pp. 1083-1090
-
-
Dunckley, M.G.1
Manoharan, M.2
Villiet, P.3
Eperon, I.C.4
Dickson, G.5
-
49
-
-
0033044501
-
Specific removal of the nonsense mutation from the mdx dystrophin mRNA using antisense oligonucleotides
-
Wilton SD, Lloyd F, Carville K, Fletcher S, Honeyman K, Agrawal S, Kole R: Specific removal of the nonsense mutation from the mdx dystrophin mRNA using antisense oligonucleotides. Neuromuscul Disord (1999) 9(5):330-338.
-
(1999)
Neuromuscul. Disord.
, vol.9
, Issue.5
, pp. 330-338
-
-
Wilton, S.D.1
Lloyd, F.2
Carville, K.3
Fletcher, S.4
Honeyman, K.5
Agrawal, S.6
Kole, R.7
-
50
-
-
0037047111
-
Chimeric snRNA molecules carrying antisense sequences against the splice junctions of exon 51 of the dystrophin pre-mRNA induce exon skipping and restoration of a dystrophin synthesis in Δ48-50 DMD cells
-
De Angelis FG, Sthandier O, Berarducci B, Toso S, Galluzzi G, Ricci E, Cossu G, Bozzoni I: Chimeric snRNA molecules carrying antisense sequences against the splice junctions of exon 51 of the dystrophin pre-mRNA induce exon skipping and restoration of a dystrophin synthesis in Δ48-50 DMD cells. Proc Natl Acad Sci USA (2002) 99(14):9456-9461.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.14
, pp. 9456-9461
-
-
De Angelis, F.G.1
Sthandier, O.2
Berarducci, B.3
Toso, S.4
Galluzzi, G.5
Ricci, E.6
Cossu, G.7
Bozzoni, I.8
-
51
-
-
3142731884
-
Inhibition of HIV-1 multiplication by antisense U7 snRNAs and siRNAs targeting cyclophilin A
-
Liu S, Asparuhova M, Brondani V, Ziekau I, Klimkait T, Schumperli D: Inhibition of HIV-1 multiplication by antisense U7 snRNAs and siRNAs targeting cyclophilin A. Nucleic Acids Res (2004) 32(12):3752-3759.
-
(2004)
Nucleic Acids Res.
, vol.32
, Issue.12
, pp. 3752-3759
-
-
Liu, S.1
Asparuhova, M.2
Brondani, V.3
Ziekau, I.4
Klimkait, T.5
Schumperli, D.6
-
52
-
-
0003826861
-
s through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides
-
s through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides. Nat Biotechnol (1999) 17(11):1097-1100.
-
(1999)
Nat. Biotechnol.
, vol.17
, Issue.11
, pp. 1097-1100
-
-
Taylor, J.K.1
Zhang, Q.Q.2
Wyatt, J.R.3
Dean, N.M.4
-
53
-
-
0035800055
-
Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-α chain
-
Karras JG, Maier MA, Lu T, Watt A, Manoharan M: Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-α chain. Biochemistry (2001) 40(26):7853-7859.
-
(2001)
Biochemistry
, vol.40
, Issue.26
, pp. 7853-7859
-
-
Karras, J.G.1
Maier, M.A.2
Lu, T.3
Watt, A.4
Manoharan, M.5
-
54
-
-
0035900725
-
Correction of alternative splicing of τ in frontotemporal dementia and Parkinsonism linked to chromosome 17
-
Kalbfuss B, Mabon SA, Misteli T: Correction of alternative splicing of τ in frontotemporal dementia and Parkinsonism linked to chromosome 17. J Biol Chem (2001) 276(46):42986-42993.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.46
, pp. 42986-42993
-
-
Kalbfuss, B.1
Mabon, S.A.2
Misteli, T.3
-
55
-
-
10744229294
-
Lamin a truncation in Hutchinson-Gilford progeria
-
De Sandre-Giovannoli A, Bernard R, Cau P, Navarro C, Amiel J, Boccaccio I, Lyonnet S, Stewart CL, Munnich A, Le Merrer M, Levy N: Lamin a truncation in Hutchinson-Gilford progeria. Science (2003) 300(5628):2055.
-
(2003)
Science
, vol.300
, Issue.5628
, pp. 2055
-
-
De Sandre-Giovannoli, A.1
Bernard, R.2
Cau, P.3
Navarro, C.4
Amiel, J.5
Boccaccio, I.6
Lyonnet, S.7
Stewart, C.L.8
Munnich, A.9
Le Merrer, M.10
Levy, N.11
-
56
-
-
0037673950
-
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome
-
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A et al: Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature (2003) 423(6937):293-298.
-
(2003)
Nature
, vol.423
, Issue.6937
, pp. 293-298
-
-
Eriksson, M.1
Brown, W.T.2
Gordon, L.B.3
Glynn, M.W.4
Singer, J.5
Scott, L.6
Erdos, M.R.7
Robbins, C.M.8
Moses, T.Y.9
Berglund, P.10
Dutra, A.11
-
57
-
-
17644373758
-
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
-
Scaffidi P, Misteli T: Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat Med (2005) 11(4):440-445.
-
(2005)
Nat. Med.
, vol.11
, Issue.4
, pp. 440-445
-
-
Scaffidi, P.1
Misteli, T.2
-
58
-
-
0035196165
-
Oligonucleotides against a splicing enhancer sequence led to dystrophin production in muscle cells from a Duchenne muscular dystrophy patient
-
Takeshima Y, Wada H, Yagi M, Ishikawa Y, Ishikawa Y, Minami R, Nakamura H, Matsuo, M: Oligonucleotides against a splicing enhancer sequence led to dystrophin production in muscle cells from a Duchenne muscular dystrophy patient. Brain Dev (2001) 23(8):788-790.
-
(2001)
Brain Dev.
, vol.23
, Issue.8
, pp. 788-790
-
-
Takeshima, Y.1
Wada, H.2
Yagi, M.3
Ishikawa, Y.4
Ishikawa, Y.5
Minami, R.6
Nakamura, H.7
Matsuo, M.8
-
59
-
-
19544363571
-
Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements
-
Bruno IG, Jin W, Cote GJ: Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements. Hum Mol Genet (2004) 13(20):2409-2420.
-
(2004)
Hum. Mol. Genet.
, vol.13
, Issue.20
, pp. 2409-2420
-
-
Bruno, I.G.1
Jin, W.2
Cote, G.J.3
-
60
-
-
0036903132
-
Systemically delivered antisense oligomers upregulate gene expression in mouse tissues
-
Sazani P, Gemignani F, Kang SH, Maier MA, Manoharan M, Persmark M, Bortner D, Kole R: Systemically delivered antisense oligomers upregulate gene expression in mouse tissues. Nat Biotechnol (2002) 20(12):1228-1233.
-
(2002)
Nat. Biotechnol.
, vol.20
, Issue.12
, pp. 1228-1233
-
-
Sazani, P.1
Gemignani, F.2
Kang, S.H.3
Maier, M.A.4
Manoharan, M.5
Persmark, M.6
Bortner, D.7
Kole, R.8
-
61
-
-
0344420060
-
Dystrophin and mutations: One gene, several proteins, multiple phenotypes
-
Muntoni F, Torelli S, Ferlini A: Dystrophin and mutations: One gene, several proteins, multiple phenotypes. Lancet Neurol (2003) 2(12):731-740.
-
(2003)
Lancet Neurol.
, vol.2
, Issue.12
, pp. 731-740
-
-
Muntoni, F.1
Torelli, S.2
Ferlini, A.3
-
62
-
-
0347003516
-
Antisense-induced multiexon skipping for Duchenne muscular dystrophy makes more sense
-
Aartsma-Rus A, Janson AA, Kaman WE, Bremmer-Bout M, van Ommen GJ, den Dunnen JT, van Deutekom JC: Antisense-induced multiexon skipping for Duchenne muscular dystrophy makes more sense. Am J Hum Genet (2004) 74(1):83-92.
-
(2004)
Am. J. Hum. Genet.
, vol.74
, Issue.1
, pp. 83-92
-
-
Aartsma-Rus, A.1
Janson, A.A.2
Kaman, W.E.3
Bremmer-Bout, M.4
van Ommen, G.J.5
den Dunnen, J.T.6
van Deutekom, J.C.7
-
63
-
-
0024353559
-
The molecular basis of muscular dystrophy in the mdx mouse: A point mutation
-
Sicinski P, Geng Y, Ryder-Cook AS, Barnard EA, Darlison MG, Barnard PJ: The molecular basis of muscular dystrophy in the mdx mouse: A point mutation. Science (1989) 244(4912):1578-1580.
-
(1989)
Science
, vol.244
, Issue.4912
, pp. 1578-1580
-
-
Sicinski, P.1
Geng, Y.2
Ryder-Cook, A.S.3
Barnard, E.A.4
Darlison, M.G.5
Barnard, P.J.6
-
64
-
-
0035793047
-
Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse
-
Mann CJ, Honeyman K, Cheng AJ, Ly T, Lloyd F, Fletcher S, Morgan JE, Partridge TA, Wilton SD: Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse. Proc Natl Acad Sci USA (2001) 98(1):42-47.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.1
, pp. 42-47
-
-
Mann, C.J.1
Honeyman, K.2
Cheng, A.J.3
Ly, T.4
Lloyd, F.5
Fletcher, S.6
Morgan, J.E.7
Partridge, T.A.8
Wilton, S.D.9
-
65
-
-
0042536463
-
Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse
-
Lu QL, Mann CJ, Lou F, Bou-Gharios G, Morris GE, Xue SA, Fletcher S, Partridge TA, Wilton SD: Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse. Nat Med (2003) 9(8):1009-1014.
-
(2003)
Nat. Med.
, vol.9
, Issue.8
, pp. 1009-1014
-
-
Lu, Q.L.1
Mann, C.J.2
Lou, F.3
Bou-Gharios, G.4
Morris, G.E.5
Xue, S.A.6
Fletcher, S.7
Partridge, T.A.8
Wilton, S.D.9
-
66
-
-
0141760549
-
Enhanced in vivo delivery of antisense oligonucleotides to restore dystrophin expression in adult mdx mouse muscle
-
Wells KE, Fletcher S, Mann CJ, Wilton SD, Wells DJ: Enhanced in vivo delivery of antisense oligonucleotides to restore dystrophin expression in adult mdx mouse muscle. FEBS Lett (2003) 552(2-3):145-149.
-
(2003)
FEBS Lett.
, vol.552
, Issue.2-3
, pp. 145-149
-
-
Wells, K.E.1
Fletcher, S.2
Mann, C.J.3
Wilton, S.D.4
Wells, D.J.5
-
67
-
-
10044240371
-
Rescue of dystrophic muscle through U7 snRNA-mediated exon skipping
-
Goyenvalle A, Vulin A, Fougerousse F, Leturcq F, Kaplan JC, Garcia L, Danos O: Rescue of dystrophic muscle through U7 snRNA-mediated exon skipping. Science (2004) 306(5702):1796-1799.
-
(2004)
Science
, vol.306
, Issue.5702
, pp. 1796-1799
-
-
Goyenvalle, A.1
Vulin, A.2
Fougerousse, F.3
Leturcq, F.4
Kaplan, J.C.5
Garcia, L.6
Danos, O.7
-
68
-
-
11844256373
-
Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles
-
Lu QL, Rabinowitz A, Chen YC, Yokota T, Yin H, Alter J, Jadoon A, Bou-Gharios G, Partridge T: Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles. Proc Natl Acad Sci USA (2005) 102(1):198-203.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.1
, pp. 198-203
-
-
Lu, Q.L.1
Rabinowitz, A.2
Chen, Y.C.3
Yokota, T.4
Yin, H.5
Alter, J.6
Jadoon, A.7
Bou-Gharios, G.8
Partridge, T.9
-
69
-
-
4344693568
-
Targeted exon skipping in transgenic hDMD mice: A model for direct preclinical screening of human-specific antisense oligonucleotides
-
Bremmer-Bout M, Aartsma-Rus A, de Meijer EJ, Kaman WE, Janson AA, Vossen RH, van Ommen GJ, den Dunnen JT, van Deutekom JC: Targeted exon skipping in transgenic hDMD mice: A model for direct preclinical screening of human-specific antisense oligonucleotides. Mol Ther (2004) 10(2):232-240.
-
(2004)
Mol. Ther.
, vol.10
, Issue.2
, pp. 232-240
-
-
Bremmer-Bout, M.1
Aartsma-Rus, A.2
de Meijer, E.J.3
Kaman, W.E.4
Janson, A.A.5
Vossen, R.H.6
van Ommen, G.J.7
den Dunnen, J.T.8
van Deutekom, J.C.9
-
70
-
-
0346749521
-
Reprogramming alternative pre-messenger RNA splicing through the use of protein-binding antisense oligonucleotides
-
Villemaire J, Dion I, Elela SA, Chabot B: Reprogramming alternative pre-messenger RNA splicing through the use of protein-binding antisense oligonucleotides. J Biol Chem (2003) 278(50):50031-50039.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.50
, pp. 50031-50039
-
-
Villemaire, J.1
Dion, I.2
Elela, S.A.3
Chabot, B.4
-
71
-
-
0037388256
-
Bifunctional antisense oligonucleotides provide a trans-acting splicing enhancer that stimulates SMN2 gene expression in patient fibroblasts
-
Skordis LA, Dunckley MG, Yue B, Eperon IC, Muntoni F: Bifunctional antisense oligonucleotides provide a trans-acting splicing enhancer that stimulates SMN2 gene expression in patient fibroblasts. Proc Natl Acad Sci USA (2003) 100(7):4114-4119.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.7
, pp. 4114-4119
-
-
Skordis, L.A.1
Dunckley, M.G.2
Yue, B.3
Eperon, I.C.4
Muntoni, F.5
-
72
-
-
0037313165
-
Correction of disease-associated exon skipping by synthetic exon-specific activators
-
Cartegni L, Krainer AR: Correction of disease-associated exon skipping by synthetic exon-specific activators. Nat Struct Biol (2003) 10(2):120-125.
-
(2003)
Nat. Struct. Biol.
, vol.10
, Issue.2
, pp. 120-125
-
-
Cartegni, L.1
Krainer, A.R.2
-
73
-
-
0038603946
-
Response to Buratti et al: Can a 'patch' in a skipped exon make the pre-mRNA splicing machine run better?
-
Eperon IC, Muntoni F: Response to Buratti et al: Can a 'patch' in a skipped exon make the pre-mRNA splicing machine run better? Trends Mol Med (2003) 9(6):233-234.
-
(2003)
Trends Mol. Med.
, vol.9
, Issue.6
, pp. 233-234
-
-
Eperon, I.C.1
Muntoni, F.2
-
74
-
-
8544283791
-
The survival motor neuron protein in spinal muscular atrophy
-
Coovert DD, Le TT, McAndrew PE, Strasswimmer J, Crawford TO, Mendell JR, Coulson SE, Androphy EJ, Prior TW, Burghes AH: The survival motor neuron protein in spinal muscular atrophy. Hum Mol Genet (1997) 6(8):1205-1214.
-
(1997)
Hum. Mol. Genet.
, vol.6
, Issue.8
, pp. 1205-1214
-
-
Coovert, D.D.1
Le, T.T.2
McAndrew, P.E.3
Strasswimmer, J.4
Crawford, T.O.5
Mendell, J.R.6
Coulson, S.E.7
Androphy, E.J.8
Prior, T.W.9
Burghes, A.H.10
-
75
-
-
0038265106
-
Can a 'patch' in a skipped exon make the pre-mRNA splicing machine run better?
-
Buratti E, Baralle FE, Pagani F: Can a 'patch' in a skipped exon make the pre-mRNA splicing machine run better? Trends Mol Med (2003) 9(6):229-232.
-
(2003)
Trends Mol. Med.
, vol.9
, Issue.6
, pp. 229-232
-
-
Buratti, E.1
Baralle, F.E.2
Pagani, F.3
-
76
-
-
0142071068
-
Putting some spine into alternative splicing
-
Khoo B, Akker SA, Chew SL: Putting some spine into alternative splicing. Trends Biotechnol (2003) 21(8):328-330.
-
(2003)
Trends Biotechnol.
, vol.21
, Issue.8
, pp. 328-330
-
-
Khoo, B.1
Akker, S.A.2
Chew, S.L.3
-
77
-
-
0346216853
-
Local gene knockdown in the brain using viral-mediated RNA interference
-
Hommel JD, Sears RM, Georgescu D, Simmons DL, DiLeone RJ: Local gene knockdown in the brain using viral-mediated RNA interference. Nat Med (2003) 9(12):1539-1544.
-
(2003)
Nat. Med.
, vol.9
, Issue.12
, pp. 1539-1544
-
-
Hommel, J.D.1
Sears, R.M.2
Georgescu, D.3
Simmons, D.L.4
DiLeone, R.J.5
-
79
-
-
0242317385
-
Small RNA: Can RNA interference be exploited for therapy?
-
Wall NR, Shi Y: Small RNA: Can RNA interference be exploited for therapy? Lancet (2003) 362(9393):1401-1403.
-
(2003)
Lancet
, vol.362
, Issue.9393
, pp. 1401-1403
-
-
Wall, N.R.1
Shi, Y.2
-
80
-
-
6044248871
-
Therapeutic potential of RNA interference
-
Stevenson M: Therapeutic potential of RNA interference. N Engl J Med (2004) 351(17):1772-1777.
-
(2004)
N. Engl. J. Med.
, vol.351
, Issue.17
, pp. 1772-1777
-
-
Stevenson, M.1
-
81
-
-
0036276110
-
Exon-specific RNAi: A tool for dissecting the functional relevance of alternative splicing
-
Celotto AM, Graveley BR: Exon-specific RNAi: A tool for dissecting the functional relevance of alternative splicing. RNA (2002) 8(6):718-724.
-
(2002)
RNA
, vol.8
, Issue.6
, pp. 718-724
-
-
Celotto, A.M.1
Graveley, B.R.2
-
82
-
-
0141608626
-
Messenger RNA reprogramming by spliceosome-mediated RNA trans-splicing
-
Garcia-Blanco MA: Messenger RNA reprogramming by spliceosome-mediated RNA trans-splicing. J Clin Invest (2003) 112(4):474-480.
-
(2003)
J. Clin. Invest.
, vol.112
, Issue.4
, pp. 474-480
-
-
Garcia-Blanco, M.A.1
|