Proteasome activity or expression is not altered by activation of the heat shock transcription factor Hsf1 in cultured fibroblasts or myoblasts

Cell Stress and Chaperones

Volumn 10, Issue 3, 2005, Pages 230-241

  Taylor, David M ^a   Kabashi, Edor ^a   Agar, Jeffrey N ^a   Minotti, Sandra ^a   Durham, Heather D ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CHYMOTRYPSIN; HEAT SHOCK PROTEIN; PEPTIDASE; PROTEASOME; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HSF1; TRYPSIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR; HSF1 PROTEIN, MOUSE; PROTEIN SUBUNIT;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FIBROBLAST; GENETIC CODE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MAMMAL CELL; MOUSE; MYOBLAST; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRESS; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; GENETICS; HEAT SHOCK RESPONSE; METABOLISM; WESTERN BLOTTING;

ANIMALIA; MAMMALIA;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; DNA-BINDING PROTEINS; FIBROBLASTS; HEAT-SHOCK RESPONSE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MICE; MYOBLASTS, SKELETAL; PLASMIDS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SUBUNITS; TRANSCRIPTION FACTORS; TRANSFECTION; UP-REGULATION;

EID: 26944432044     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1379/CSC-119R.1     Document Type: Article

References (63)

1. ALS CNTF Treatment Study Group. 1996. A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. Neurology 46: 1244-1249.
2. Anderson SP, Howroyd P, Liu J, et al. 2004. The transcriptional response to a peroxisome proliferator-activated receptor alpha agonist includes increased expression of proteome maintenance genes. J Biol Chem 279: 52390-52398.
3. Arribas J, Castano JG. 1990. Kinetic studies of the differential effect of detergents on the peptidase activities of the multicatalytic proteinase from rat liver. J Biol Chem 265: 13969-13973.
4. Batulan Z, Shinder GA, Minotti S, et al. 2003. High threshold for induction of the stress response in motor neurons is associated with failure to activate HSF1. J Neurosci 23: 5789-5798.
5. Beedholm R, Clark BF, Rattan SI. 2004. Mild heat stress stimulates 20S proteasome and its 11S activator in human fibroblasts undergoing aging in vitro. Cell Stress Chaperones 9: 49-57.
6. Bruening W, Roy J, Giasson B, Figlewicz DA, Mushynski WE, Durham HD. 1999. Upregulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis. J Neurochem 72: 693-699.
7. Cascio P, Call M, Petre BM, Walz T, Goldberg AL. 2002. Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes. EMBO J 21: 2636-2645.
8. Causton HC, Ren B, Koh SS, et al. 2001. Remodeling of yeast genome expression in response to environmental changes. Mol Biol Cell 12: 323-337.
9. Chen D, Toone WM, Mata J, et al. 2003. Global transcriptional responses of fission yeast to environmental stress. Mol Biol Cell 14: 214-229.
10. Cheroni C, Reviani P, Cascio S, DeBiasi C, Monti C, Bendotti C. 2005. Accumulation of human SOD1 and ubiquitinated deposits in the spinal cord of SOD1G93A mice during motor neuron disease progression correlates with a decrease of proteasome. Neurobiol Dis 18: 509-522.
11. Ciechanover A, Brundin P. 2003. The ubiquitin proteasome system in neurodegenerative diseases. Sometimes the chicken, sometimes the egg. Neuron 40: 427-446.
12. Dewji NN, Do C. 1996. Heat shock factor-1 mediates the transcriptional activation of Alzheimer's beta-amyloid precursor protein gene in response to stress. Brain Res Mol Brain Res 35: 325-328.
13. Ding Q, Bruce-Keller AJ, Chen Q, Keller JN. 2004. Analysis of gene expression in neural cells subject to chronic proteasome inhibition. Free Radic Biol Med 36: 445-455.
14. Ding Q, Reinacker K, Dimayuga E, et al. 2003. Role of the proteasome in protein oxidation and neural viability following low-level oxidative stress. FEBS Lett 546: 228-232.
15. Fleming JA, Lightcap ES, Sadis S, Thoroddsen V, Bulawa CE, Blackman RK. 2002. Complementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341. Proc Natl Acad Sci U S A 99: 1461-1466.
16. Gasch AP, Spellman PT, Kao CM, et al. 2000. Genomic expression programs in the response of yeast cells to environmental changes. Mol Biol Cell 11: 4241-4257.
17. Glickman MH, Ciechanover A. 2002. The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82: 373-428.
18. Grune T. 2000. Oxidative stress, aging and the proteasomal system. Biogerontology 1: 31-40.
19. Grune T, Reinheckel T, Joshi M, Davies KJ. 1995. Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome. J Biol Chem 270: 2344-2351.
20. Hahn JS, Hu Z, Thiele DJ, Iyer VR. 2004. Genome-wide analysis of the biology of stress responses through heat shock transcription factor. Mol Cell Biol 24: 5249-5256.
21. Jagoe RT, Goldberg AL. 2001. What do we really know about the ubiquitin-proteasome pathway in muscle atrophy? Curr Opin Clin Nutr Metab Care 4: 183-190.
22. Jho DH, Engelhard HH, Gandhi R, Chao J, Babcock T, Ong E, Espat NJ. 2004. Ciliary neurotrophic factor upregulates ubiquitin-proteasome components in a rat model of neuronal injury. Cytokine 27: 142-151.
23. Kabashi E, Agar JN, Taylor DM, Minotti S, Durham HD. 2004. Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis. J Neurochem 89: 1325-1335.
24. Kawazoe Y, Nakai A, Tanabe M, Nagata K. 1998. Proteasome inhibition leads to the activation of all members of the heat-shock-factor family. Eur J Biochem 255: 356-362.
25. Kieran D, Kalmar B, Dick JR, Riddoch-Contreras J, Burnstock G, Greensmith L. 2004. Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice. Nat Med 10: 402-405.
26. Kim D, Kim SH, Li GC. 1999. Proteasome inhibitors MG132 and lactacystin hyperphosphorylate HSF1 and induce hsp70 and hsp27 expression. Biochem Biophys Res Commun 254: 264-268.
27. Kloetzel PM. 2001. Antigen processing by the proteasome. Nat Rev Mol Cell Biol 2: 179-187.
28. Kopp F, Dahlmann B, Kuehn L. 2001. Reconstitution of hybrid proteasomes from purified PA700-20 S complexes and PA28alphabeta activator: ultrastructure and peptidase activities. J Mol Biol 313: 465-471.
29. Kuckelkorn U, Knuehl C, Boes-Fabian B, Drung I, Kloetzel PM. 2000. The effect of heat shock on 20S/26S proteasomes. Biol Chem 381: 1017-1023.
30. Kwak MK, Wakabayashi N, Greenlaw JL, Yamamoto M, Kensler TW. 2003a. Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway. Mol Cell Biol 23: 8786-8794.
31. Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW. 2003b. Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival. J Biol Chem 278: 8135-8145.
32. Lee CS, Tee LY, Warmke T, Vinjamoori A, Cai A, Fagan AM, Snider BJ. 2004. A proteasomal stress response: pre-treatment with proteasome inhibitors increases proteasome activity and reduces neuronal vulnerability to oxidative injury. J Neurochem 91: 996-1006.
33. Mannhaupt G, Schnall R, Karpov V, Vetter I, Feldmann H. 1999. Rpn4p acts as a transcription factor by binding to PACE, a nonamer box found upstream of 26S proteasomal and other genes in yeast. FEBS Lett 450: 27-34.
34. McMillan DR, Xiao X, Shao L, Graves K, Benjamin IJ. 1998. Targeted disruption of heat shock transcription factor 1 abolishes thermotolerance and protection against heat-inducible apoptosis. J Biol Chem 273: 7523-7528.
35. Meiners S, Heyken D, Weller A, Ludwig A, Stangl K, Kloetzel PM, Kruger E. 2003. Inhibition of proteasome activity induces concerted expression of proteasome genes and de novo formation of mammalian proteasomes. J Biol Chem.
36. Meriin AB, Gabai VL, Yaglom J, Shifrin VI, Sherman MY. 1998. Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis. J Biol Chem 273: 6373-6379.
37. Morimoto RI. 1998. Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. Genes Dev 12: 3788-3796.
38. Morimoto RI, Santoro MG. 1998. Stress-inducible responses and heat shock proteins: new pharmacologic targets for cytoprotection. Nat Biotechnol 16: 833-838.
39. Motohashi H, Yamamoto M. 2004. Nrf2-Keap1 defines a physiologically important stress response mechanism. Trends Mol Med 10: 549-557.
40. Muchowski PJ, Wacker JL. 2005. Modulation of neurodegeneration by molecular chaperones. Nat Rev Neurosci 6: 11-22.
41. Murray JI, Whitfield ML, Trinklein ND, Myers RM, Brown PO, Botstein D. 2004. Diverse and specific gene expression responses to stresses in cultured human cells. Mol Biol Cell 15: 2361-2374.
42. Nguyen T, Sherratt PJ, Huang HC, Yang CS, Pickett CB. 2003. Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome. J Biol Chem 278: 4536-4541.
43. Nguyen T, Yang CS, Pickett CB. 2004. The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress. Free Radic Biol Med 37: 433-441.
44. O'Brien ML, Cunningham ML, Spear BT, Glauert HP. 2002. Peroxisome proliferators do not activate the transcription factors AP-1, early growth response-1, or heat shock factors 1 and 2 in rats or hamsters. Toxicol Sci 69: 139-148.
45. Petrucelli L, Dawson TM. 2004. Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system. Ann Med 36: 315-320.
46. Pirkkala L, Alastalo TP, Zuo XX, Benjamin IJ, Sistonen L. 2000. Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway. Mol Cell Biol 20: 2670-2675.
47. Rechsteiner M, Hill CP. 2005. Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors. Trends Cell Biol 15: 27-33.
48. Reits EAJ, Benham AM, Plougastel B, Neefjes J, Trowsdale J. 1997. Dynamics of proteasome distribution in living cells. EMBO J 16: 6087-6094.
49. Rock KL, Gramm C, Rothstein L, et al. 1994. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78: 761-771.
50. Ross CA, Poirier MA. 2004. Protein aggregation and neurodegenerative disease. Nat Med 10(Suppl): S10-S17.
51. Sherman MY, Goldberg AL. 2001. Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases [review]. Neuron 29: 15-32.
52. Shringarpure R, Grune T, Davies KJA. 2001. Protein oxidation and 20S proteasome-dependent proteolysis in mammalian cells [review]. Cell Mol Life Sci 58: 1442-1450.
53. Sitte N, Merker K, Grune T. 1998. Proteasome-dependent degradation of oxidized proteins in MRC-5 fibroblasts. FEBS Lett 440: 399-402.
54. Tanahashi N, Murakami Y, Minami Y, Shimbara N, Hendil KB, Tanaka K. 2000. Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis. J Biol Chem 275: 14336-14345.
55. Taylor JR. 1996. An Introduction to Error Analysis: The Study of Uncertainties in Physical Measurements 2nd ed., University Science Books, Sausalito, CA.
56. Trinklein ND, Murray JI, Hartman SJ, Botstein D, Myers RM. 2003. The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response. Mol Biol Cell 15: 1254-1261.
57. Verbeke P, Fonager J, Clark BF, Rattan SI. 2001. Heat shock response and ageing: mechanisms and applications. Cell Biol Int 25: 845-857.
58. Voellmy R. 2004. On mechanisms that control heat shock transcription factor activity in metazoan cells. Cell Stress Chaperones 9: 122-133.
59. Wang Y, Morgan WD. 1994. Cooperative interaction of human HSF1 heat shock transcription factor with promoter DNA. Nucleic Acids Res 22: 3113-3118.
60. Westerheide SD, Bosman JD, Mbadugha BN, et al. 2004. Celastrols as inducers of the heat shock response and cytoprotection. J Biol Chem 279: 56053-56060.
61. Whitby FG, Masters EI, Kramer L, Knowlton JR, Yao Y, Wang CC, Hill CP. 2000. Structural basis for the activation of 20S proteasomes by 11S regulators. Nature 408: 115-120.
62. Xie Y, Varshavsky A. 2001. RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit. Proc Natl Acad Sci U S A 98: 3056-3061.
63. Zuo J, Rungger D, Voellmy R. 1995. Multiple layers of regulation of human heat shock transcription factor 1. Mol Cell Biol 15: 4319-4330.