메뉴 건너뛰기




Volumn 33, Issue 10, 2005, Pages 2323-2331

Carbon monoxide, but not endothelin-1, plays a major role for the hepatic microcirculation in a murine model of early systemic inflammation

Author keywords

Inflammation; Liver; Microcirculation

Indexed keywords

CARBON MONOXIDE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; MESSENGER RNA; TEZOSENTAN;

EID: 26444458748     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000182794.42733.71     Document Type: Article
Times cited : (17)

References (52)
  • 1
    • 0034108825 scopus 로고    scopus 로고
    • The epidemiology of the systemic inflammatory response
    • Brun-Buisson C: The epidemiology of the systemic inflammatory response. Intensive Care Med 2000; 26(Suppl 1):S64-S74
    • (2000) Intensive Care Med , vol.26 , Issue.SUPPL. 1
    • Brun-Buisson, C.1
  • 2
    • 0029024552 scopus 로고
    • Systemic inflammatory response syndrome, sepsis, severe sepsis and septic shock: Incidence, morbidities and outcomes in surgical ICU patient
    • Pittet D, Rangel-Frausto S, Li N, et al: Systemic inflammatory response syndrome, sepsis, severe sepsis and septic shock: Incidence, morbidities and outcomes in surgical ICU patient. Intensive Care Med 1995; 21:302-309
    • (1995) Intensive Care Med , vol.21 , pp. 302-309
    • Pittet, D.1    Rangel-Frausto, S.2    Li, N.3
  • 3
    • 0036737893 scopus 로고    scopus 로고
    • Hepatic dysfunction increases length of stay and risk of death after injury
    • Harbrecht BG, Zenati MS, Doyle HR, et al: Hepatic dysfunction increases length of stay and risk of death after injury. J Trauma 2002; 53:517-523
    • (2002) J Trauma , vol.53 , pp. 517-523
    • Harbrecht, B.G.1    Zenati, M.S.2    Doyle, H.R.3
  • 4
    • 0023859136 scopus 로고
    • A novel potent vasoconstrictor peptide produced by vascular endothelial cells
    • Yanagisawa M, Kurihara H, Kimura S, et al: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332:411-415
    • (1988) Nature , vol.332 , pp. 411-415
    • Yanagisawa, M.1    Kurihara, H.2    Kimura, S.3
  • 5
    • 0025080836 scopus 로고
    • Endothelin, a potent peptide agonist in the liver
    • Gandhi CR, Stephenson K, Olson MS: Endothelin, a potent peptide agonist in the liver. J Biol Chem 1990; 265:17432-17435
    • (1990) J Biol Chem , vol.265 , pp. 17432-17435
    • Gandhi, C.R.1    Stephenson, K.2    Olson, M.S.3
  • 6
    • 0027496798 scopus 로고
    • Endothelin receptors in rat liver: Lipocytes as a contractile target for endothelin 1
    • Housset C, Rockey DC, Bissell DM: Endothelin receptors in rat liver: Lipocytes as a contractile target for endothelin 1. Proc Natl Acad Sci USA 1993; 90:9266-9270
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9266-9270
    • Housset, C.1    Rockey, D.C.2    Bissell, D.M.3
  • 7
    • 0028052485 scopus 로고
    • ET-1 induced alterations of hepatic microcirculation: Sinusoidal and extrasinusoidal sites of action
    • Bauer M, Zhang JX, Bauer I, et al: ET-1 induced alterations of hepatic microcirculation: sinusoidal and extrasinusoidal sites of action. Am J Physiol 1994; 267:G143-G149
    • (1994) Am J Physiol , vol.267
    • Bauer, M.1    Zhang, J.X.2    Bauer, I.3
  • 9
    • 0025904585 scopus 로고
    • Elevated plasma levels of endothelin in patients with sepsis syndrome
    • Weitzberg E, Lundberg JM, Rudehill A: Elevated plasma levels of endothelin in patients with sepsis syndrome. Circ Shock 1991; 33:222-227
    • (1991) Circ Shock , vol.33 , pp. 222-227
    • Weitzberg, E.1    Lundberg, J.M.2    Rudehill, A.3
  • 10
    • 0030023763 scopus 로고    scopus 로고
    • Endotoxin pretreatment enhances portal venous contractile response to endothelin-1
    • Pannen BH, Bauer M, Zhang JX, et al: Endotoxin pretreatment enhances portal venous contractile response to endothelin-1. Am J Physiol 1996; 270:H7-H15
    • (1996) Am J Physiol , vol.270
    • Pannen, B.H.1    Bauer, M.2    Zhang, J.X.3
  • 11
    • 3042517374 scopus 로고    scopus 로고
    • Heme oxygenase modulates hepatic leukocyte sequestration via changes in sinusoidal tone in systemic inflammation in mice
    • Wunder C, Scott JR, Lush CW, et al: Heme oxygenase modulates hepatic leukocyte sequestration via changes in sinusoidal tone in systemic inflammation in mice. Microvasc Res 2004; 68:20-29
    • (2004) Microvasc Res , vol.68 , pp. 20-29
    • Wunder, C.1    Scott, J.R.2    Lush, C.W.3
  • 12
    • 0030271238 scopus 로고    scopus 로고
    • Gaseous monoxides: A new class of microvascular regulator in the liver
    • Suematsu M, Wakabayashi Y, Ishimura Y: Gaseous monoxides: A new class of microvascular regulator in the liver. Cardiovasc Res 1996; 32:679-686
    • (1996) Cardiovasc Res , vol.32 , pp. 679-686
    • Suematsu, M.1    Wakabayashi, Y.2    Ishimura, Y.3
  • 13
    • 0032005790 scopus 로고    scopus 로고
    • Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation
    • Goda N, Suzuki K, Naito M, et al: Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation. J Clin Invest 1998; 101:604-612
    • (1998) J Clin Invest , vol.101 , pp. 604-612
    • Goda, N.1    Suzuki, K.2    Naito, M.3
  • 14
    • 0036894517 scopus 로고    scopus 로고
    • Endothelin-1 and heme oxygenase-1 as modulators of sinusoidal tone in the stress-exposed rat liver
    • Rensing H, Bauer I, Zhang JX, et al: Endothelin-1 and heme oxygenase-1 as modulators of sinusoidal tone in the stress-exposed rat liver. Hepatology 2002; 36:1453-1465
    • (2002) Hepatology , vol.36 , pp. 1453-1465
    • Rensing, H.1    Bauer, I.2    Zhang, J.X.3
  • 15
    • 0032531163 scopus 로고    scopus 로고
    • Protective role of endogenous carbon monoxide in hepatic microcirculatory dysfunction after hemorrhagic shock in rats
    • Pannen BH, Kohler N, Hole B, et al: Protective role of endogenous carbon monoxide in hepatic microcirculatory dysfunction after hemorrhagic shock in rats. J Clin Invest 1998; 102:1220-1228
    • (1998) J Clin Invest , vol.102 , pp. 1220-1228
    • Pannen, B.H.1    Kohler, N.2    Hole, B.3
  • 16
    • 0032766706 scopus 로고    scopus 로고
    • Pharmacology of tezosentan, new endothelin receptor antagonist designed for parenteral use
    • Clozel M, Ramuz H, Clozel JP, et al: Pharmacology of tezosentan, new endothelin receptor antagonist designed for parenteral use. J Pharmacol Exp Ther 1999; 290:840-846
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 840-846
    • Clozel, M.1    Ramuz, H.2    Clozel, J.P.3
  • 17
    • 0037487004 scopus 로고    scopus 로고
    • ETA and ETB receptor function in pancreatitis-associated microcirculatory failure, inflammation, and parenchymal injury
    • Plusczyk T, Witzel B, Menger MD, et al: ETA and ETB receptor function in pancreatitis-associated microcirculatory failure, inflammation, and parenchymal injury. Am J Physiol Gastrointest Liver Physiol 2003; 285: G145-G153
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.285
    • Plusczyk, T.1    Witzel, B.2    Menger, M.D.3
  • 18
    • 0025860484 scopus 로고
    • Influence of aromatic hydrocarbons on the metabolism of dichloromethane to carbon monoxide in rats
    • Pankow D, Matschiner F, Weigmann HJ: Influence of aromatic hydrocarbons on the metabolism of dichloromethane to carbon monoxide in rats. Toxicology 1991; 68:89-100
    • (1991) Toxicology , vol.68 , pp. 89-100
    • Pankow, D.1    Matschiner, F.2    Weigmann, H.J.3
  • 19
    • 7044269687 scopus 로고    scopus 로고
    • Cooperative effect of biliverdin and carbon monoxide on survival of mice in immune-mediated liver injury
    • Sass G, Seyfried S, Parreira SM, et al: Cooperative effect of biliverdin and carbon monoxide on survival of mice in immune-mediated liver injury. Hepatology 2004; 40:1128-1135
    • (2004) Hepatology , vol.40 , pp. 1128-1135
    • Sass, G.1    Seyfried, S.2    Parreira, S.M.3
  • 20
    • 0036588447 scopus 로고    scopus 로고
    • Inhibition of haem oxygenase activity increases leukocyte accumulation in the liver following limb ischaemia-reperfusion in mice
    • Wunder C, Brock RW, McCarter SD, et al: Inhibition of haem oxygenase activity increases leukocyte accumulation in the liver following limb ischaemia-reperfusion in mice. J Physiol 2002; 540:1013-1021
    • (2002) J Physiol , vol.540 , pp. 1013-1021
    • Wunder, C.1    Brock, R.W.2    McCarter, S.D.3
  • 21
    • 1842411863 scopus 로고    scopus 로고
    • Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension
    • Hocher B, Thone-Reineke C, Rohmeiss P, et al: Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension. J Clin Invest 1997; 99:1380-1389
    • (1997) J Clin Invest , vol.99 , pp. 1380-1389
    • Hocher, B.1    Thone-Reineke, C.2    Rohmeiss, P.3
  • 22
    • 0027169767 scopus 로고
    • A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples
    • Chomczynski P: A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques 1993; 15:532-537
    • (1993) Biotechniques , vol.15 , pp. 532-537
    • Chomczynski, P.1
  • 23
    • 85048550370 scopus 로고    scopus 로고
    • Erythropoietin-induced excessive erythrocytosis activates the tissue endothelin system in mice
    • Quaschning T, Ruschitzka F, Stallmach T, et al: Erythropoietin-induced excessive erythrocytosis activates the tissue endothelin system in mice. FASEB J 2003; 17:259-261
    • (2003) FASEB J , vol.17 , pp. 259-261
    • Quaschning, T.1    Ruschitzka, F.2    Stallmach, T.3
  • 24
    • 0032808710 scopus 로고    scopus 로고
    • Microcirculatory perfusion deficits are not essential for remote parenchymal injury within the liver
    • Brock RW, Carson MW, Harris KA, et al: Microcirculatory perfusion deficits are not essential for remote parenchymal injury within the liver. Am J Physiol 1999; 27: G55-G60
    • (1999) Am J Physiol , vol.27
    • Brock, R.W.1    Carson, M.W.2    Harris, K.A.3
  • 25
    • 0031239425 scopus 로고    scopus 로고
    • High-resolution microscopic determination of hepatic NADH fluorescence for in vivo monitoring of tissue oxygenation during hemorrhagic shock and resuscitation
    • Vollmar B, Burkhardt M, Minor T, et al: High-resolution microscopic determination of hepatic NADH fluorescence for in vivo monitoring of tissue oxygenation during hemorrhagic shock and resuscitation. Microvasc Res 1997; 54:164-173
    • (1997) Microvasc Res , vol.54 , pp. 164-173
    • Vollmar, B.1    Burkhardt, M.2    Minor, T.3
  • 26
    • 0022404412 scopus 로고
    • Hepatic microcirculatory failure after ischemia and reperfusion: Improvement with ATP-MgC12 treatment
    • Clemens MG, McDonagh PF, Chaudry IH, et al: Hepatic microcirculatory failure after ischemia and reperfusion: Improvement with ATP-MgC12 treatment. Am J Physiol 1985; 248:H804-H811
    • (1985) Am J Physiol , vol.248
    • Clemens, M.G.1    McDonagh, P.F.2    Chaudry, I.H.3
  • 27
    • 0036258002 scopus 로고    scopus 로고
    • The role of endogenous heme oxygenase in the initiation of liver injury following limb ischemia/reperfusion
    • Nie RG, McCarter SD, Harris KA, et al: The role of endogenous heme oxygenase in the initiation of liver injury following limb ischemia/reperfusion. J Hepatol 2002; 36:624-630
    • (2002) J Hepatol , vol.36 , pp. 624-630
    • Nie, R.G.1    McCarter, S.D.2    Harris, K.A.3
  • 28
    • 0032733172 scopus 로고    scopus 로고
    • Contribution of endothelin-1 to myocardial injury in a murine model of myocarditis: Acute effects of bosentan, an endothelin receptor antagonist
    • Ono K, Matsumori A, Shioi T, et al: Contribution of endothelin-1 to myocardial injury in a murine model of myocarditis: Acute effects of bosentan, an endothelin receptor antagonist Circulation 1999; 100:1823-1829
    • (1999) Circulation , vol.100 , pp. 1823-1829
    • Ono, K.1    Matsumori, A.2    Shioi, T.3
  • 29
    • 13644272554 scopus 로고    scopus 로고
    • A remission spectroscopy system for in vivo monitoring of hemoglobin oxygen saturation in murine hepatic sinusoids, in early systemic inflammation
    • Wunder C, Brock RW, Krug A, et al: A remission spectroscopy system for in vivo monitoring of hemoglobin oxygen saturation in murine hepatic sinusoids, in early systemic inflammation. Comp Hepatol 2005; 4:1
    • (2005) Comp Hepatol , vol.4 , pp. 1
    • Wunder, C.1    Brock, R.W.2    Krug, A.3
  • 30
    • 0036581719 scopus 로고    scopus 로고
    • Endothelin 1 impairs oxygen delivery in livers from LPS-primed animals
    • Baveja R, Yokoyama Y, Korneszczuk K, et al: Endothelin 1 impairs oxygen delivery in livers from LPS-primed animals. Shock 2002; 17:383-388
    • (2002) Shock , vol.17 , pp. 383-388
    • Baveja, R.1    Yokoyama, Y.2    Korneszczuk, K.3
  • 31
    • 0037253077 scopus 로고    scopus 로고
    • Endothelin receptor antagonist bosentan improves microcirculatory blood flow in splanchnic organs in septic shock
    • Krejci V, Hiltebrand LB, Erni D, et al: Endothelin receptor antagonist bosentan improves microcirculatory blood flow in splanchnic organs in septic shock. Crit Care Med 2003; 31:203-210
    • (2003) Crit Care Med , vol.31 , pp. 203-210
    • Krejci, V.1    Hiltebrand, L.B.2    Erni, D.3
  • 32
    • 20644455950 scopus 로고    scopus 로고
    • Initiation of remote hepatic injury in the rat: Interactions between Kupffer cells, tumor necrosis factor-alpha, and microvascular perfusion
    • Brock RW, Lawlor DK, Harris KA, et al: Initiation of remote hepatic injury in the rat: Interactions between Kupffer cells, tumor necrosis factor-alpha, and microvascular perfusion. Hepatology 1999; 30:137-142
    • (1999) Hepatology , vol.30 , pp. 137-142
    • Brock, R.W.1    Lawlor, D.K.2    Harris, K.A.3
  • 33
    • 0029780321 scopus 로고    scopus 로고
    • Mortality following lower limb ischemia-reperfusion: A systemic inflammatory response?
    • Yassin MM, Barros DS, Parks G, et al: Mortality following lower limb ischemia-reperfusion: A systemic inflammatory response? World J Surg 1996; 20:961-966
    • (1996) World J Surg , vol.20 , pp. 961-966
    • Yassin, M.M.1    Barros, D.S.2    Parks, G.3
  • 34
    • 0031776019 scopus 로고    scopus 로고
    • Regulation of endothelin synthesis in hepatic endothelial cells
    • Bakes AT, Olson MS: Regulation of endothelin synthesis in hepatic endothelial cells. Am J Physiol 1998; 274:G1068-G1076
    • (1998) Am J Physiol , vol.274
    • Bakes, A.T.1    Olson, M.S.2
  • 35
    • 0033609060 scopus 로고    scopus 로고
    • Smads bind directly to the Jun family of AP-1 transcription factors
    • Liberati NT, Datto MB, Frederick JP, et al: Smads bind directly to the Jun family of AP-1 transcription factors. Proc Natl Acad Sci U S A 1999; 96:4844-4849
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 4844-4849
    • Liberati, N.T.1    Datto, M.B.2    Frederick, J.P.3
  • 36
    • 0027163936 scopus 로고
    • Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP
    • Malek AM, Greene AL, Izumo S: Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP. Proc Natl Acad Sci U S A 1993; 90):5999-6003
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 5999-6003
    • Malek, A.M.1    Greene, A.L.2    Izumo, S.3
  • 37
    • 0035012538 scopus 로고    scopus 로고
    • Kupffer cell-initiated remote hepatic injury following bilateral hind limb ischemia is complement dependent
    • Brock RW, Nie RG, Harris KA, et al: Kupffer cell-initiated remote hepatic injury following bilateral hind limb ischemia is complement dependent. Am J Physiol Gastrointest Liver Physiol 2001; 280:G279-G284
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.280
    • Brock, R.W.1    Nie, R.G.2    Harris, K.A.3
  • 38
    • 0035490919 scopus 로고    scopus 로고
    • Regional distribution of endothelin-1 and endothelin converting enzyme-1 in porcine endotoxemia
    • Magder S, Javeshghani D, Cernacek P, et al: Regional distribution of endothelin-1 and endothelin converting enzyme-1 in porcine endotoxemia. Shock 2001; 16:320-325
    • (2001) Shock , vol.16 , pp. 320-325
    • Magder, S.1    Javeshghani, D.2    Cernacek, P.3
  • 39
    • 0031017599 scopus 로고    scopus 로고
    • Effect of bacterial lipopolysaccharide on endothelin-1 production in human vascular endothelial clls
    • Ros J, Leivas A, Jimenez W, et al: Effect of bacterial lipopolysaccharide on endothelin-1 production in human vascular endothelial clls. J Hepatol 1997; 26:81-87
    • (1997) J Hepatol , vol.26 , pp. 81-87
    • Ros, J.1    Leivas, A.2    Jimenez, W.3
  • 41
    • 0034073597 scopus 로고    scopus 로고
    • Functional significance of endothelin B receptors in mediating sinusoidal and extrasinusoidal effects of endothelins in the intact rat liver
    • Bauer M, Bauer I, Sonin NV, et al: Functional significance of endothelin B receptors in mediating sinusoidal and extrasinusoidal effects of endothelins in the intact rat liver. Hepatology 2000; 31:937-947
    • (2000) Hepatology , vol.31 , pp. 937-947
    • Bauer, M.1    Bauer, I.2    Sonin, N.V.3
  • 42
    • 12344274713 scopus 로고    scopus 로고
    • Remote trauma sensitizes hepatic microcirculation to endothelin via caveolin inhibition of eNOS activity
    • Ashburn JH, Baveja R, Kresge N, et al: Remote trauma sensitizes hepatic microcirculation to endothelin via caveolin inhibition of eNOS activity. Shock 2004; 22:120-130
    • (2004) Shock , vol.22 , pp. 120-130
    • Ashburn, J.H.1    Baveja, R.2    Kresge, N.3
  • 43
    • 0029891589 scopus 로고    scopus 로고
    • Endothelin induced contractility of stellate cells from normal and cirrhotic rat liver: Implications for regulation of portal pressure and resistance
    • Rockey DC, Weisiger RA: Endothelin induced contractility of stellate cells from normal and cirrhotic rat liver: Implications for regulation of portal pressure and resistance. Hepatology 1996; 24:233-240
    • (1996) Hepatology , vol.24 , pp. 233-240
    • Rockey, D.C.1    Weisiger, R.A.2
  • 44
    • 33750700881 scopus 로고    scopus 로고
    • A time-dependent balance between endothelins and nitric oxide regulating portal resistance after endotoxin
    • Pannen BH, Bauer M, Zhang JX, et al: A time-dependent balance between endothelins and nitric oxide regulating portal resistance after endotoxin. Am J Physiol 1996; 271: H1953-H1961
    • (1996) Am J Physiol , vol.271
    • Pannen, B.H.1    Bauer, M.2    Zhang, J.X.3
  • 45
    • 0028856163 scopus 로고
    • Carbon monoxide: An endogenous modulator of sinusoidal tone in the perfused rat liver
    • Suematsu M, Goda N, Sano Tm et al: Carbon monoxide: An endogenous modulator of sinusoidal tone in the perfused rat liver. J Clin Invest 1995; 96:2431-2437
    • (1995) J Clin Invest , vol.96 , pp. 2431-2437
    • Suematsu, M.1    Goda, N.2    Sano, T.3
  • 46
    • 0032171410 scopus 로고    scopus 로고
    • Oxidative chemistry of nitric oxide: The roles of superoxide, peroxynitrite, and carbon dioxide
    • Squadrito GL, Pryor WA: Oxidative chemistry of nitric oxide: The roles of superoxide, peroxynitrite, and carbon dioxide. Free Radic Biol Med 1998; 25:392-403
    • (1998) Free Radic Biol Med , vol.25 , pp. 392-403
    • Squadrito, G.L.1    Pryor, W.A.2
  • 47
    • 0035186392 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase in the regulation of leucocyte recruitment
    • Hickey MJ: Role of inducible nitric oxide synthase in the regulation of leucocyte recruitment. Clin Sci (Lond) 2001; 100:1-12
    • (2001) Clin Sci (Lond) , vol.100 , pp. 1-12
    • Hickey, M.J.1
  • 48
    • 0027190038 scopus 로고
    • The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus
    • Kawada N, Tran-Thi TA, Klein H, et al: The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus. Eur J Biochem 1993; 213:815-823
    • (1993) Eur J Biochem , vol.213 , pp. 815-823
    • Kawada, N.1    Tran-Thi, T.A.2    Klein, H.3
  • 49
    • 1942485280 scopus 로고    scopus 로고
    • Nitric oxide decreases in endothelin-1 secretion through the activation of soluble guanylate cyclase
    • Kelly LK, Wedgwood S, Steinhorn RH, et al: Nitric oxide decreases in endothelin-1 secretion through the activation of soluble guanylate cyclase. Am J Physiol Lung Cell Mol Physiol 2003; 286:L984-L991
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.286
    • Kelly, L.K.1    Wedgwood, S.2    Steinhorn, R.H.3
  • 50
    • 0036670319 scopus 로고    scopus 로고
    • Effects of endothelin receptor antagonists on endothelin-1 and inducible nitric oxide synthase genes in a rat endotoxic shock model
    • Hirata Y, Ishimaru S: Effects of endothelin receptor antagonists on endothelin-1 and inducible nitric oxide synthase genes in a rat endotoxic shock model. Clin Sci (Lond) 2002; 103(Suppl 48):332S-335S
    • (2002) Clin Sci (Lond) , vol.103 , Issue.SUPPL. 48
    • Hirata, Y.1    Ishimaru, S.2
  • 51
    • 11244279637 scopus 로고    scopus 로고
    • Inhalation of carbon monoxide prevents liver injury and inflammation following hind limb ischemia/reperfusion
    • Ott MC, Scott JR, Bihari A, et al: Inhalation of carbon monoxide prevents liver injury and inflammation following hind limb ischemia/reperfusion. FASEB J 2005; 19:106-108
    • (2005) FASEB J , vol.19 , pp. 106-108
    • Ott, M.C.1    Scott, J.R.2    Bihari, A.3
  • 52
    • 3042609714 scopus 로고    scopus 로고
    • Endogenous heme oxygenase induction is a critical mechanism attenuating apoptosis and restoring microvascular perfusion following limb ischemia/reperfusion
    • McCarter SD, Akyea TG, Lu X, et al: Endogenous heme oxygenase induction is a critical mechanism attenuating apoptosis and restoring microvascular perfusion following limb ischemia/reperfusion. Surgery 2004; 136:67-75
    • (2004) Surgery , vol.136 , pp. 67-75
    • McCarter, S.D.1    Akyea, T.G.2    Lu, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.