Functional significance of endothelin B receptors in mediating sinusoidal and extrasinusoidal effects of endothelins in the intact rat liver

Hepatology

Volumn 31, Issue 4, 2000, Pages 937-947

  Bauer, Michael ^a,b   Bauer, Inge ^a   Sonin, Natalie V ^a   Kresge, Nicole ^a   Baveja, Rajiv ^a   Yokoyama, Yukihiro ^a   Harding, David ^a   Zhang, Jian X ^a   Clemens, Mark G ^a  

^a UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN; ENDOTHELIN B RECEPTOR; LACTATE DEHYDROGENASE; NITRIC OXIDE SYNTHASE;

ANIMAL TISSUE; ARTICLE; ENZYME ACTIVATION; ENZYME RELEASE; LIVER PROTECTION; LIVER SINUSOID; NONHUMAN; PORTAL VEIN BLOOD FLOW; PORTAL VEIN BLOOD PRESSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STELLATE CELL;

EID: 0034073597     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/he.2000.5922     Document Type: Article

References (7)

1. Pannen BH, Bauer M, Zhang JX, Robotham JL, Clemens MG. Endotoxin pretreatment enhances portal venous contractile response to endothelin-1. Am J Physiol 1996;270:H7-H15.
2. Pannen BHJ, Bauer M, Zhang JX, Robotham JL, Clemens MG. A time-dependent balance between endothelins and nitric oxide regulating portal resistance after endotoxin. Am J Physiol 1996;271:H1953-H1961.
3. Housset CN, Rockey DC, Friedman SL, Bissell DM. Hepatic lipocytes: a major target for endothelin-1. J Hepatol 1995;22:55-60.
4. Bauer M, Zhang JX, Bauer I, Clemens MG. ET-1 induced alterations of hepatic microcirculation: sinusoidal and extrasinusoidal sites of action. Am J Physiol 1994;267:G143-G149.
5. Zhang JX, Bauer M, Clemens MG. Vessel and target cell specific actions of endothelin-1 and endothelin-3 in rat liver. Am J Physiol 1995;269:G269-G277.
6. Rockey D. The cellular pathogenesis of portal hypertension: stellate cell contractility, endothelin, and nitric oxide. HEPATOLOGY 1997;25:2-5.
7. Rockey DC, Housset CN, Friedman SL. Activation-dependent contractility of rat hepatic lipocytes in culture and in vivo. J Clin Invest 1993;92:1795-1804.