Abundant neuritic inclusions and microvacuolar changes in a case of diffuse Lewy body disease with the A53T mutation in the α-synuclein gene

Acta Neuropathologica

Volumn 110, Issue 3, 2005, Pages 298-305

  Yamaguchi, Keiji ^a   Cochran, Elizabeth J ^b   Murrell, Jill R ^a   Polymeropoulos, Mihael H ^c   Shannon, Kathleen M ^b   Crowther, R Anthony ^d   Goedert, Michel ^d   Ghetti, Bernardino ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

^d MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Synuclein; A53T mutation; Diffuse Lewy body disease; Lewy neurites; Microvacuolar changes

Indexed keywords

ALANINE; ALPHA SYNUCLEIN; EOSIN; HEMATOXYLIN; LEVODOPA; PROTEIN ANTIBODY; TAU PROTEIN; THREONINE;

ADULT; ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; BRAIN REGION; CARBOXY TERMINAL SEQUENCE; CASE REPORT; CELL INCLUSION; CELL ISOLATION; CELL LOSS; CELL VACUOLE; COGNITIVE DEFECT; DEATH; DEMENTIA; DIFFUSE LEWY BODY DISEASE; ELECTRON MICROSCOPY; FAMILY HISTORY; FEMALE; GENE CLUSTER; GENE MUTATION; GRANULAR CELL; HALLUCINATION; HUMAN; IDIOPATHIC DISEASE; LEWY BODY; LIMBIC CORTEX; MEYNERT BASAL NUCLEUS; MOTONEURON NUCLEUS; NEURITE; NEUROFIBRILLARY TANGLE; NEUROFILAMENT; NUCLEUS ACCUMBENS; OLIVARY NUCLEUS; PARKINSONISM; PERIKARYON; PRIORITY JOURNAL; SENILE PLAQUE; SPHEROID CELL; STAINING; SUBSTANTIA NIGRA; VAGUS NERVE;

ADULT; ALPHA-SYNUCLEIN; BRAIN; CYTOPLASM; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INCLUSION BODIES; INHERITANCE PATTERNS; LEWY BODIES; LEWY BODY DISEASE; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MUTATION; NEURITES; RETROSPECTIVE STUDIES; VACUOLES;

EID: 26444445118     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-005-1042-4     Document Type: Article

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