Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit

Cancer Cell

Volumn 1, Issue 2, 2002, Pages 181-191

  Chan, Tung O ^a   Rodeck, Ulrich ^a   Chan, Andrew M ^b   Kimmelman, Alec C ^b   Rittenhouse, Susan E ^a   Panayotou, George ^c   Tsichlis, Philip N ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P85; PROTEIN TYROSINE KINASE; RAC1 PROTEIN; RAS PROTEIN; GROWTH PROMOTOR; INTEGRIN; ONCOPROTEIN; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; PROTEIN SUBUNIT; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; ENZYME SUBUNIT; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; ONCOGENE H RAS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; PROTEIN SYNTHESIS REGULATION; AMINO ACID SEQUENCE; ANIMAL; CELL MEMBRANE; CELL STRAIN 3T3; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; PROTEIN MOTIF; SRC HOMOLOGY DOMAIN;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3 CELLS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CELL MEMBRANE; ENZYME ACTIVATION; GROWTH SUBSTANCES; GTP PHOSPHOHYDROLASES; INTEGRINS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN SUBUNITS; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RAC1 GTP-BINDING PROTEIN; RAS PROTEINS; SRC HOMOLOGY DOMAINS; TUMOR SUPPRESSOR PROTEINS;

EID: 0036490708     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(02)00033-8     Document Type: Article

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