-
1
-
-
0031000180
-
The first genome from the third domain of life
-
Clayton, R.A., White, O., Ketchum, K.A., Venter, J.C. (1997) The first genome from the third domain of life. Nature 29, 459-462.
-
(1997)
Nature
, vol.29
, pp. 459-462
-
-
Clayton, R.A.1
White, O.2
Ketchum, K.A.3
Venter, J.C.4
-
2
-
-
26244465561
-
-
Worth Publishing, New York
-
Lehninger, A.L., (1993) Principles. Biochem.. Worth Publishing, New York, pp. 1-1013.
-
(1993)
Principles. Biochem.
, pp. 1-1013
-
-
Lehninger, A.L.1
-
3
-
-
12444323307
-
-
Scientific American Books, New York
-
Lodish, H., Baltimore, D., Berk, A., Zipursky, S.L., Matsudaira, P., Darnell, J. (1995) Mol. Cell Biol.. Scientific American Books, New York, pp. 1-1417.
-
(1995)
Mol. Cell Biol.
, pp. 1-1417
-
-
Lodish, H.1
Baltimore, D.2
Berk, A.3
Zipursky, S.L.4
Matsudaira, P.5
Darnell, J.6
-
4
-
-
0032478498
-
Microbial genome analyses: Global comparisons of transport capabilities based on phylogenies, bioenergetics and substrate specificities
-
Paulsen, I.T., Sliwinski, M.K., Saier, M.H. Jr. (1998) Microbial genome analyses: global comparisons of transport capabilities based on phylogenies, bioenergetics and substrate specificities. J. Mol. Biol. 277, 573-592.
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 573-592
-
-
Paulsen, I.T.1
Sliwinski, M.K.2
Saier Jr., M.H.3
-
5
-
-
0032560586
-
Unified inventory of established and putative transporters encoded within the complete genome of Saccharomyces cerevisiae
-
Paulsen, I.T., Sliwinski, M.K., Nelissen, B., Goffeau, A., Saier, M.H. Jr. (1998) Unified inventory of established and putative transporters encoded within the complete genome of Saccharomyces cerevisiae. FEBS Lett. 430, 116-125.
-
(1998)
FEBS Lett.
, vol.430
, pp. 116-125
-
-
Paulsen, I.T.1
Sliwinski, M.K.2
Nelissen, B.3
Goffeau, A.4
Saier Jr., M.H.5
-
6
-
-
0343603660
-
A functional-phylogenetic classification system for transmembrane solute transporters
-
Saier, M.H. Jr. (2000) A functional-phylogenetic classification system for transmembrane solute transporters. Microbiol. Mol. Biol. Rev. 64, 354-411.
-
(2000)
Microbiol. Mol. Biol. Rev.
, vol.64
, pp. 354-411
-
-
Saier Jr., M.H.1
-
7
-
-
0026621245
-
ABC transporters: From microorganisms to man
-
Higgins, C.F. (1992) ABC transporters: from microorganisms to man. Curr. Opin. Cell Biol. 8, 67-113.
-
(1992)
Curr. Opin. Cell Biol.
, vol.8
, pp. 67-113
-
-
Higgins, C.F.1
-
8
-
-
0031006578
-
Compound missense mutations in the sodium/D-glucose cotransporter result in trafficking defects
-
Martin, M.G., Lostao, M.P., Turk, E., Lam, J., Kreman, M., Wright, E.M. (1997) Compound missense mutations in the sodium/D-glucose cotransporter result in trafficking defects. Gastroenterology 112, 1206-1212.
-
(1997)
Gastroenterology
, vol.112
, pp. 1206-1212
-
-
Martin, M.G.1
Lostao, M.P.2
Turk, E.3
Lam, J.4
Kreman, M.5
Wright, E.M.6
-
9
-
-
0033860638
-
Heteromeric amino acid transporters explain inherited aminoacidurias
-
Palacin, M., Bertran, J., Zorzano, A. (2000) Heteromeric amino acid transporters explain inherited aminoacidurias. Curr. Opin. Nephrol. Hypertens. 9, 547-553.
-
(2000)
Curr. Opin. Nephrol. Hypertens.
, vol.9
, pp. 547-553
-
-
Palacin, M.1
Bertran, J.2
Zorzano, A.3
-
10
-
-
0032912589
-
Structure and function of the CFTR chloride channel
-
Sheppard, D.N., Welsh, M.J. (1999) Structure and function of the CFTR chloride channel. Physiol. Rev. 79, S23-45.
-
(1999)
Physiol. Rev.
, vol.79
-
-
Sheppard, D.N.1
Welsh, M.J.2
-
11
-
-
0034634741
-
Promoter polymorphism of the 5-HT transporter and Alzheimer's disease
-
Hu, M., Retz, W., Baader, M., et al. (2000) Promoter polymorphism of the 5-HT transporter and Alzheimer's disease. Neurosci. Lett. 294, 63-65.
-
(2000)
Neurosci. Lett.
, vol.294
, pp. 63-65
-
-
Hu, M.1
Retz, W.2
Baader, M.3
-
12
-
-
0030921878
-
Association of a polymorphism in the dopamine-transporter gene with Parkinson's disease
-
Le Couteur, D.G., Leighton, P.W., McCann, S.J., Pond, S. (1997) Association of a polymorphism in the dopamine-transporter gene with Parkinson's disease. Mov. Disord. 12, 760-763.
-
(1997)
Mov. Disord.
, vol.12
, pp. 760-763
-
-
Le Couteur, D.G.1
Leighton, P.W.2
McCann, S.J.3
Pond, S.4
-
13
-
-
0034241856
-
Association of the dopamine transporter gene with Parkinson's disease in Korean patients
-
Kim, J.W., Kim, D.H., Kim, S.H., and Cha, J.K. (2000) Association of the dopamine transporter gene with Parkinson's disease in Korean patients. J. Korean Med. Sci. 15, 449-451.
-
(2000)
J. Korean Med. Sci.
, vol.15
, pp. 449-451
-
-
Kim, J.W.1
Kim, D.H.2
Kim, S.H.3
Cha, J.K.4
-
14
-
-
0033837202
-
Variability and validity of polymorphism association studies in Parkinson's disease
-
Tan, E.K., Khajavi, M., Thornby, J.I., Nagamitsu, S., Jankovic, J., and Ashizawa, T. (2000) Variability and validity of polymorphism association studies in Parkinson's disease. Neurology 55, 533-538.
-
(2000)
Neurology
, vol.55
, pp. 533-538
-
-
Tan, E.K.1
Khajavi, M.2
Thornby, J.I.3
Nagamitsu, S.4
Jankovic, J.5
Ashizawa, T.6
-
15
-
-
0033801280
-
Membrane transporters
-
Lee, V.H. (2000) Membrane transporters. Eur. J. Pharm. Sci. 11, S41-S50.
-
(2000)
Eur. J. Pharm. Sci.
, vol.11
-
-
Lee, V.H.1
-
16
-
-
0035996829
-
Altered drug disposition of the platelet activating factor antagonist apafant in mdrla knockout mice
-
Leusch, A., Volz, A., Muller, G., et al. (2002) Altered drug disposition of the platelet activating factor antagonist apafant in mdrla knockout mice. Eur. J. Pharm. Sci. 16, 119-128.
-
(2002)
Eur. J. Pharm. Sci.
, vol.16
, pp. 119-128
-
-
Leusch, A.1
Volz, A.2
Muller, G.3
-
17
-
-
0033756459
-
Transporter-mediated permeation of drugs across the blood-brain barrier
-
Tamai, I. and Tsuji, A. (2000) Transporter-mediated permeation of drugs across the blood-brain barrier. J. Pharm. Sci. 89, 1371-1388.
-
(2000)
J. Pharm. Sci.
, vol.89
, pp. 1371-1388
-
-
Tamai, I.1
Tsuji, A.2
-
18
-
-
0032874193
-
Kinetic and biochemical analysis of carrier-mediated efflux of drugs through the blood-brain and blood-cerebrospinal fluid barriers: Importance in the drug delivery to the brain
-
Sugiyama, Y., Kusuhara, H., and Suzuki, H. (1999) Kinetic and biochemical analysis of carrier-mediated efflux of drugs through the blood-brain and blood-cerebrospinal fluid barriers: importance in the drug delivery to the brain. J. Control Release. 62, 179-186.
-
(1999)
J. Control Release
, vol.62
, pp. 179-186
-
-
Sugiyama, Y.1
Kusuhara, H.2
Suzuki, H.3
-
19
-
-
0033849976
-
Cellular and molecular aspects of drug transport in the kidney
-
Inui, K.I., Masuda, S., and Saito, H. (2000) Cellular and molecular aspects of drug transport in the kidney. Kidney Int. 58, 944-958.
-
(2000)
Kidney Int.
, vol.58
, pp. 944-958
-
-
Inui, K.I.1
Masuda, S.2
Saito, H.3
-
20
-
-
0029584879
-
Biology of membrane transport proteins
-
Sadee, W., Drubbisch, V., and Amidon, G.L. (1995) Biology of membrane transport proteins. Pharm Res. 12, 1823-1837.
-
(1995)
Pharm Res.
, vol.12
, pp. 1823-1837
-
-
Sadee, W.1
Drubbisch, V.2
Amidon, G.L.3
-
21
-
-
0033250545
-
Multidrug-resistance transporters
-
Silverman, J.A. (1999) Multidrug-resistance transporters. Pharm. Biotechnol. 12, 353-386.
-
(1999)
Pharm. Biotechnol.
, vol.12
, pp. 353-386
-
-
Silverman, J.A.1
-
22
-
-
0033254582
-
Drug transport and targeting. Intestinal transport
-
Oh, D.M., Han, H.K., and Amidon, G.L. (1999) Drug transport and targeting. Intestinal transport. Pharm. Biotechnol. 12, 59-88.
-
(1999)
Pharm. Biotechnol.
, vol.12
, pp. 59-88
-
-
Oh, D.M.1
Han, H.K.2
Amidon, G.L.3
-
23
-
-
0036644903
-
Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918
-
Kruijtzer, C. M., Beijnen, J. H., Rosing, H., et al. (2002) Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918. J. Clin. Oncol. 1, 2943-2950.
-
(2002)
J. Clin. Oncol.
, vol.1
, pp. 2943-2950
-
-
Kruijtzer, C.M.1
Beijnen, J.H.2
Rosing, H.3
-
24
-
-
0033938105
-
Neurotransmitter transporters: Fruitful targets for CNS drug discovery
-
Iversen, L. (2000) Neurotransmitter transporters: fruitful targets for CNS drug discovery. Mol. Psychiatry. 5, 357-362.
-
(2000)
Mol. Psychiatry
, vol.5
, pp. 357-362
-
-
Iversen, L.1
-
25
-
-
0032620210
-
A mutation in the promoter of the multidrug resistance gene (MDR1) in human hematological malignancies may contribute to the pathogenesis of resistant disease
-
Rund, D., Azar, I., and Shperling, O. (1999) A mutation in the promoter of the multidrug resistance gene (MDR1) in human hematological malignancies may contribute to the pathogenesis of resistant disease. Adv. Exp. Med. Biol. 457, 71-75.
-
(1999)
Adv. Exp. Med. Biol.
, vol.457
, pp. 71-75
-
-
Rund, D.1
Azar, I.2
Shperling, O.3
-
26
-
-
0022833525
-
Multidrug resistance
-
Gerlach, J.H., Kartner, N., Bell, D.R., and Ling, V. (1986) Multidrug resistance. Cancer Surv. 5, 25-46.
-
(1986)
Cancer Surv.
, vol.5
, pp. 25-46
-
-
Gerlach, J.H.1
Kartner, N.2
Bell, D.R.3
Ling, V.4
-
27
-
-
84912924789
-
Multidrug resistance
-
DeVita,V.T.Jr., et al. eds., Lippincott Williams & Wilkins Publishers, Philadelphia
-
Dalton, W.S. and Miller, T.P. (1991) Multidrug resistance, in Cancer: Principles and Practice of Oncolgy.DeVita,V.T.Jr., et al. eds., Lippincott Williams & Wilkins Publishers, Philadelphia, pp. 1-13.
-
(1991)
Cancer: Principles and Practice of Oncolgy
, pp. 1-13
-
-
Dalton, W.S.1
Miller, T.P.2
-
28
-
-
0036593544
-
Novel animal-health drug targets from ligand-gated chloride channels
-
Raymond, V. and Sattelle, D.B. (2002 ) Novel animal-health drug targets from ligand-gated chloride channels. Nat. Rev. Drug Discov. 1, 427-436.
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 427-436
-
-
Raymond, V.1
Sattelle, D.B.2
-
29
-
-
0033656073
-
The impact of genomics on therapeutic drug development
-
Kennedy, G.C. (2000) The impact of genomics on therapeutic drug development. EXS. 89, 1-10.
-
(2000)
EXS
, vol.89
, pp. 1-10
-
-
Kennedy, G.C.1
-
30
-
-
0033569516
-
Pharmacogenomics: Translating functional genomics into rational therapeutics
-
Evans, W.E. and Relling, M.V. (1999) Pharmacogenomics: translating functional genomics into rational therapeutics. Science 286, 487-491.
-
(1999)
Science
, vol.286
, pp. 487-491
-
-
Evans, W.E.1
Relling, M.V.2
-
31
-
-
0033403326
-
Technologies for detecting genetic polymorphisms in pharmacogenomics
-
Shi, M.M., Bleavins, M.R., and de la Iglesia, F.A. (1999) Technologies for detecting genetic polymorphisms in pharmacogenomics. Mol. Diagn. 4, 343-351.
-
(1999)
Mol. Diagn.
, vol.4
, pp. 343-351
-
-
Shi, M.M.1
Bleavins, M.R.2
De La Iglesia, F.A.3
-
32
-
-
85046914149
-
Pharmacogenomics: The implementation phase
-
Sadee, W. (2002) Pharmacogenomics: the implementation phase. AAPS PharmSci 4, E5.
-
(2002)
AAPS PharmSci.
, vol.4
-
-
Sadee, W.1
-
33
-
-
0033928586
-
Impact of genomics on drug discovery and clinical medicine
-
Emilien, G., Ponchon, M., Caldas, C., Isacson, O., and Maloteaux, J.M. (2000) Impact of genomics on drug discovery and clinical medicine. QJM. 93, 391-423.
-
(2000)
QJM
, vol.93
, pp. 391-423
-
-
Emilien, G.1
Ponchon, M.2
Caldas, C.3
Isacson, O.4
Maloteaux, J.M.5
-
34
-
-
0033428029
-
Impact of pharmacogenomics on the clinical laboratory
-
Hess, P. and Cooper, D. (1999) Impact of pharmacogenomics on the clinical laboratory. Mol. Diagn. 4, 289-298.
-
(1999)
Mol. Diagn.
, vol.4
, pp. 289-298
-
-
Hess, P.1
Cooper, D.2
-
35
-
-
0034567052
-
Pharmacogenetics and pharmacogenomics in the discovery and development of medicines
-
Roses, A.D. (2000) Pharmacogenetics and pharmacogenomics in the discovery and development of medicines. Novartis Found Symp. 229, 63-66.
-
(2000)
Novartis Found Symp.
, vol.229
, pp. 63-66
-
-
Roses, A.D.1
-
36
-
-
33748428120
-
Pharmacogenomics: The genomics of drug response
-
March, R. (2000) Pharmacogenomics: the genomics of drug response. Yeast 17, 16-21.
-
(2000)
Yeast
, vol.17
, pp. 16-21
-
-
March, R.1
-
37
-
-
0002150481
-
Moderne probleme der Human-genetik
-
Vogel, F. (1959) Moderne probleme der Human-genetik. Ergeb. Inn. Med. Kinderheilkd. 12, 52-125.
-
(1959)
Ergeb. Inn. Med. Kinderheilkd.
, vol.12
, pp. 52-125
-
-
Vogel, F.1
-
38
-
-
0031035007
-
Polymorphisms in drug-metabolizing enzymes: What is their clinical relevance and why do they exist?
-
Nebert, D.W. (1997) Polymorphisms in drug-metabolizing enzymes: what is their clinical relevance and why do they exist? Am. J. Hum. Genet. 60, 265-271.
-
(1997)
Am. J. Hum. Genet.
, vol.60
, pp. 265-271
-
-
Nebert, D.W.1
-
39
-
-
0036500993
-
Systems biology: A brief overview
-
Kitano H. (2002) Systems biology: a brief overview. Science 295, 1662-1664.
-
(2002)
Science
, vol.295
, pp. 1662-1664
-
-
Kitano, H.1
-
40
-
-
0032695572
-
Association of the dopamine transporter gene (DAT1) with poor methylphenidate response
-
Winsberg, B.G. and Comings, D.E. (1999) Association of the dopamine transporter gene (DAT1) with poor methylphenidate response. J. Am. Acad. Child Adolesc. Psychiatry. 38, 1474-1477.
-
(1999)
J. Am. Acad. Child Adolesc. Psychiatry
, vol.38
, pp. 1474-1477
-
-
Winsberg, B.G.1
Comings, D.E.2
-
41
-
-
2542440464
-
Interactions between hepatic Mrp4 and Sult2A as revealed by the constitutive androstane receptor and Mrp4 knockout mice
-
Assem, M., Schuetz, E.G., Leggas, M., et al. (2004) Interactions between hepatic Mrp4 and Sult2A as revealed by the constitutive androstane receptor and Mrp4 knockout mice. J. Biol. Chem. 279, 22250-22257.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 22250-22257
-
-
Assem, M.1
Schuetz, E.G.2
Leggas, M.3
-
42
-
-
0142070958
-
Regulated secretion of macrophage migration inhibitory factor is mediated by a non-classical pathway involving an ABC transporter
-
Flieger, O., Engling, A., Bucala, R., Lue, H., Nickel, W., and Bernhagen, J. (2003) Regulated secretion of macrophage migration inhibitory factor is mediated by a non-classical pathway involving an ABC transporter. FEBS Lett. 11, 78-86.
-
(2003)
FEBS Lett.
, vol.11
, pp. 78-86
-
-
Flieger, O.1
Engling, A.2
Bucala, R.3
Lue, H.4
Nickel, W.5
Bernhagen, J.6
-
43
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer, S., Burk, O., von Richter, O., et al. (2000) Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. USA 97, 3473-3478.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
-
44
-
-
0006463359
-
Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
-
Lesch, K.P., Bengel, D., Heils, A., et al. (1996) Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274, 1527-1531.
-
(1996)
Science
, vol.274
, pp. 1527-1531
-
-
Lesch, K.P.1
Bengel, D.2
Heils, A.3
-
45
-
-
0031736757
-
Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine
-
Smeraldi, E., Zanardi, R., Benedetti, F., Di Bella, D., Perez, J., and Catalano, M. (1998) Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine. Mol. Psychiatry. 3, 508-511.
-
(1998)
Mol. Psychiatry
, vol.3
, pp. 508-511
-
-
Smeraldi, E.1
Zanardi, R.2
Benedetti, F.3
Di Bella, D.4
Perez, J.5
Catalano, M.6
-
46
-
-
0034677021
-
Serotonin transporter gene polymorphism and antidepressant response
-
Kim, D.K., Lim, S.W., Lee, S., et al. (2000) Serotonin transporter gene polymorphism and antidepressant response. Neuroreport. 11, 215-219.
-
(2000)
Neuroreport
, vol.11
, pp. 215-219
-
-
Kim, D.K.1
Lim, S.W.2
Lee, S.3
-
47
-
-
0033807374
-
Allelic variation in the serotonin transporter promoter affects onset of paroxetine treatment response in late-life depression
-
Pollock, B.G., Ferrell, R.E., Mulsant, B.H., et al. (2000) Allelic variation in the serotonin transporter promoter affects onset of paroxetine treatment response in late-life depression. Neuropsychopharmacology 23, 587-590.
-
(2000)
Neuropsychopharmacology
, vol.23
, pp. 587-590
-
-
Pollock, B.G.1
Ferrell, R.E.2
Mulsant, B.H.3
-
48
-
-
0033984363
-
Efficacy of paroxetine in depression is influenced by a functional polymorphism within the promoter of the serotonin transporter gene
-
Zanardi, R., Benedetti, F., Di Bella, D., Catalano, M., and Smeraldi, E. (2000) Efficacy of paroxetine in depression is influenced by a functional polymorphism within the promoter of the serotonin transporter gene. J. Clin. Psychopharmacol. 20, 105-107.
-
(2000)
J. Clin. Psychopharmacol.
, vol.20
, pp. 105-107
-
-
Zanardi, R.1
Benedetti, F.2
Di Bella, D.3
Catalano, M.4
Smeraldi, E.5
-
49
-
-
0036325415
-
Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome
-
Camilleri, M., Atanasova, E., Carlson, P.J., et al. (2002) Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome. Gastroenterology 123, 425-432.
-
(2002)
Gastroenterology
, vol.123
, pp. 425-432
-
-
Camilleri, M.1
Atanasova, E.2
Carlson, P.J.3
-
50
-
-
0025931429
-
Nucleoside triphosphates are required to open the CFTR chloride channel
-
Anderson, M.P., Berger, H.A., Rich, D.P., Gregory, R.J., Smith, A.E., and Welsh, M.J. (1991) Nucleoside triphosphates are required to open the CFTR chloride channel. Cell 67, 775-784.
-
(1991)
Cell
, vol.67
, pp. 775-784
-
-
Anderson, M.P.1
Berger, H.A.2
Rich, D.P.3
Gregory, R.J.4
Smith, A.E.5
Welsh, M.J.6
-
51
-
-
0026077676
-
Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel
-
Berger, H.A., Anderson, M.P., Gregory, R.J., et al. (1991) Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel. J. Clin. Invest. 88, 1422-1431.
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 1422-1431
-
-
Berger, H.A.1
Anderson, M.P.2
Gregory, R.J.3
-
52
-
-
0033669078
-
Support for allelic association of a polymorphic site in the promoter region of the serotonin transporter gene with risk for alcohol dependence
-
Lichtermann, D., Hranilovic, D., Trixler, M., et al. (2000) Support for allelic association of a polymorphic site in the promoter region of the serotonin transporter gene with risk for alcohol dependence. Am. J. Psychiatry. 157, 2045-2047.
-
(2000)
Am. J. Psychiatry
, vol.157
, pp. 2045-2047
-
-
Lichtermann, D.1
Hranilovic, D.2
Trixler, M.3
-
53
-
-
0032744001
-
Structural, mechanistic and clinical aspects of MRP1
-
Hipfner, D.R., Deeley, R.G., and Cole, S.P. (1999) Structural, mechanistic and clinical aspects of MRP1. Biochim. Biophys. Acta 1461, 359-376.
-
(1999)
Biochim. Biophys. Acta
, vol.1461
, pp. 359-376
-
-
Hipfner, D.R.1
Deeley, R.G.2
Cole, S.P.3
-
54
-
-
0032750225
-
The multidrug resistance protein family
-
Borst, P., Evers, R., Kool, M., and Wijnholds, J. (1999) The multidrug resistance protein family. Biochim. Biophys. Acta 1461, 347-357.
-
(1999)
Biochim. Biophys. Acta
, vol.1461
, pp. 347-357
-
-
Borst, P.1
Evers, R.2
Kool, M.3
Wijnholds, J.4
-
55
-
-
0344927562
-
Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
-
Konig, J., Nies, A.T., Cui, Y., Leier, I., and Keppler, D. (1999) Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance. Biochim. Biophys. Acta 1461, 377-394.
-
(1999)
Biochim. Biophys. Acta
, vol.1461
, pp. 377-394
-
-
Konig, J.1
Nies, A.T.2
Cui, Y.3
Leier, I.4
Keppler, D.5
-
56
-
-
0027978128
-
A unique gene organization for two cholinergic markers, choline acetyltransferase and a putative vesicular transporter of acetylcholine
-
Bejanin, S., Cervini, R., Mallet, J., and Berrard, S. (1994) A unique gene organization for two cholinergic markers, choline acetyltransferase and a putative vesicular transporter of acetylcholine. J. Biol. Chem. 269, 21944-21947.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21944-21947
-
-
Bejanin, S.1
Cervini, R.2
Mallet, J.3
Berrard, S.4
-
57
-
-
0028048214
-
Functional identification of a vesicular acetylcholine transporter and its expression from a "cholinergic" gene locus
-
Erickson, J.D., Varoqui, H., Schafer, M.K., et al. (1994) Functional identification of a vesicular acetylcholine transporter and its expression from a "cholinergic" gene locus. J. Biol. Chem. 269, 21929-21932.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21929-21932
-
-
Erickson, J.D.1
Varoqui, H.2
Schafer, M.K.3
-
58
-
-
26244448572
-
-
Protein Data Bank (PDB)
-
Protein Data Bank (PDB): http://www.rcsb.org/pdb/
-
-
-
-
61
-
-
0033071210
-
Genotype/Phenotype analysis of a photoreceptor-specific ATP-binding cassette transporter gene, ABCR, in Stargardt disease
-
Lewis, R.A., Shroyer, N.F., Singh, N., et al. (1999) Genotype/Phenotype analysis of a photoreceptor-specific ATP-binding cassette transporter gene, ABCR, in Stargardt disease. Am. J. Hum. Genet. 64, 422-434.
-
(1999)
Am. J. Hum. Genet.
, vol.64
, pp. 422-434
-
-
Lewis, R.A.1
Shroyer, N.F.2
Singh, N.3
-
62
-
-
0344364566
-
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis
-
Tokuhiro, S., Yamada, R., Chang, X., et al. (2003) An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nat Genet. 35, 341-348.
-
(2003)
Nat Genet.
, vol.35
, pp. 341-348
-
-
Tokuhiro, S.1
Yamada, R.2
Chang, X.3
-
63
-
-
0032748555
-
Pharmacogenetics and pharmacogenomics: Why is this relevant to the clinical geneticist?
-
Nebert, D.W. (1999) Pharmacogenetics and pharmacogenomics: why is this relevant to the clinical geneticist? Clin Genet. 56, 247-258.
-
(1999)
Clin Genet.
, vol.56
, pp. 247-258
-
-
Nebert, D.W.1
-
64
-
-
0033733489
-
Pharmacogenetics: A molecular sophistication or a new clinical tool for cardiologists?
-
Dirckx, C., Donati, M.B., and Iacoviello, L. (2000) Pharmacogenetics: a molecular sophistication or a new clinical tool for cardiologists? Ital. Heart J. 1, 662-666.
-
(2000)
Ital. Heart J.
, vol.1
, pp. 662-666
-
-
Dirckx, C.1
Donati, M.B.2
Iacoviello, L.3
-
65
-
-
10744220811
-
Effects of dopamine transporter and receptor polymorphisms on smoking cessation in a bupropion clinical trial
-
Lerman, C., Shields, P.G., Wileyto, E.P., et al. (2003) Effects of dopamine transporter and receptor polymorphisms on smoking cessation in a bupropion clinical trial. Health Psychol. 22, 541-548.
-
(2003)
Health Psychol.
, vol.22
, pp. 541-548
-
-
Lerman, C.1
Shields, P.G.2
Wileyto, E.P.3
-
66
-
-
0031823433
-
Genomics and drugs: Finding the optimal drug for the right patient
-
Sadee, W. (1998) Genomics and drugs: finding the optimal drug for the right patient. Pharm. Res. 15, 959-963.
-
(1998)
Pharm. Res.
, vol.15
, pp. 959-963
-
-
Sadee, W.1
-
67
-
-
0347185032
-
Pharmacogenomics and "individualized drug therapy": High expectations and disappointing achievements
-
Nebert, D.W., Jorge-Nebert, L., and Vesell, E.S. (2003) Pharmacogenomics and "individualized drug therapy": high expectations and disappointing achievements. Am. J. Pharmacogenomics. 3, 361-370.
-
(2003)
Am. J. Pharmacogenomics
, vol.3
, pp. 361-370
-
-
Nebert, D.W.1
Jorge-Nebert, L.2
Vesell, E.S.3
-
68
-
-
0032813808
-
Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
-
Brooks-Wilson, A., Marcil, M., Clee, S. M., et al. (1999) Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nature Genet. 22, 336-345.
-
(1999)
Nature Genet.
, vol.22
, pp. 336-345
-
-
Brooks-Wilson, A.1
Marcil, M.2
Clee, S.M.3
-
69
-
-
0032813809
-
The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease
-
Bodzioch, M., Orso, E., Klucken, J., et al. (1999) The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease. Nature Genet. 22, 347-351.
-
(1999)
Nature Genet.
, vol.22
, pp. 347-351
-
-
Bodzioch, M.1
Orso, E.2
Klucken, J.3
-
70
-
-
0012119330
-
Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration
-
Allikmets, R., Shroyer, N. F., Singh, N., et al. (1997) Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration. Science 277, 1805-1807.
-
(1997)
Science
, vol.277
, pp. 1805-1807
-
-
Allikmets, R.1
Shroyer, N.F.2
Singh, N.3
-
71
-
-
0033804333
-
A comprehensive survey of sequence variation in the ABCA4 (ABCR) gene in Stargardt disease and age-related macular degeneration
-
Rivera, A., White, K., Stohr, H., et al. (2000) A comprehensive survey of sequence variation in the ABCA4 (ABCR) gene in Stargardt disease and age-related macular degeneration. Am. J. Hum. Genet. 67, 800-813.
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 800-813
-
-
Rivera, A.1
White, K.2
Stohr, H.3
-
72
-
-
17644443114
-
Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: Evidence for a defect in protein trafficking
-
Dixon, P. H., Weerasekera, N., Linton, K. J., et al. (2000) Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking. Hum. Molec. Genet. 9, 1209-1217.
-
(2000)
Hum. Molec. Genet.
, vol.9
, pp. 1209-1217
-
-
Dixon, P.H.1
Weerasekera, N.2
Linton, K.J.3
-
73
-
-
0027375464
-
Abnormal messenger RNA expression and a missense mutation in patients with X-linked adrenoleukodystrophy
-
Cartier, N., Sarde, C.-O., Douar, A.-M., Mosser, J., Mandel, J.-L., and Aubourg, P. (1993) Abnormal messenger RNA expression and a missense mutation in patients with X-linked adrenoleukodystrophy. Hum. Molec. Genet. 2, 1949-1951.
-
(1993)
Hum. Molec. Genet.
, vol.2
, pp. 1949-1951
-
-
Cartier, N.1
Sarde, C.-O.2
Douar, A.-M.3
Mosser, J.4
Mandel, J.-L.5
Aubourg, P.6
-
74
-
-
0030060578
-
Identification of mutations in the ALD-gene of 20 families with adrenoleukodystrophy/adrenomyeloneuropathy
-
Krasemann, E. W., Meier, V., Korenke, G. C., Hunneman, D. H., and Hanefeld, F. (1996) Identification of mutations in the ALD-gene of 20 families with adrenoleukodystrophy/adrenomyeloneuropathy. Hum. Genet. 97, 194-197.
-
(1996)
Hum. Genet.
, vol.97
, pp. 194-197
-
-
Krasemann, E.W.1
Meier, V.2
Korenke, G.C.3
Hunneman, D.H.4
Hanefeld, F.5
-
75
-
-
0028017998
-
Occipital horn syndrome and a mild Menkes phenotype associated with splice site mutations at the MNK locus
-
Kaler, S. G., Gallo, L. K., Proud, V. K., et al. (1994) Occipital horn syndrome and a mild Menkes phenotype associated with splice site mutations at the MNK locus. Nature Genet. 8, 195-202.
-
(1994)
Nature Genet.
, vol.8
, pp. 195-202
-
-
Kaler, S.G.1
Gallo, L.K.2
Proud, V.K.3
-
76
-
-
0028820678
-
Molecular pathology and haplotype analysis of Wilson disease in Mediterranean populations
-
Figus, A., Angius, A., Loudianos, G., et al. (1995) Molecular pathology and haplotype analysis of Wilson disease in Mediterranean populations. Am. J. Hum. Genet. 57, 1318-1324.
-
(1995)
Am. J. Hum. Genet.
, vol.57
, pp. 1318-1324
-
-
Figus, A.1
Angius, A.2
Loudianos, G.3
-
77
-
-
0345480774
-
Identification of three novel mutations and a high frequency of the arg778-to-leu mutation in Korean patients with Wilson disease
-
Kim, E. K., Yoo, O. J., Song, K. Y., et al. (1998) Identification of three novel mutations and a high frequency of the arg778-to-leu mutation in Korean patients with Wilson disease. Hum. Mutat. 11, 275-278.
-
(1998)
Hum. Mutat.
, vol.11
, pp. 275-278
-
-
Kim, E.K.1
Yoo, O.J.2
Song, K.Y.3
-
78
-
-
12244295084
-
Band 3 Tuscaloosa: pro327-to-arg327 substitution in the cytoplasmic domain of erythrocyte band 3 protein associated with spherocytic hemolytic anemia and partial deficiency of protein 4.2
-
Jarolim, P., Palek, J., Rubin, H. L., Prchal, J. T., Korsgren, C., and Cohen, C. M. (1991) Band 3 Tuscaloosa: pro327-to-arg327 substitution in the cytoplasmic domain of erythrocyte band 3 protein associated with spherocytic hemolytic anemia and partial deficiency of protein 4.2. (Abstract) Blood 78 (suppl.), 252a.
-
(1991)
(Abstract) Blood
, vol.78
, Issue.SUPPL.
-
-
Jarolim, P.1
Palek, J.2
Rubin, H.L.3
Prchal, J.T.4
Korsgren, C.5
Cohen, C.M.6
-
79
-
-
0035746511
-
Phenotype and genotype variation in primary carnitine deficiency
-
Wang, Y., Korman, S. H., Ye, J., et al. (2001) Phenotype and genotype variation in primary carnitine deficiency. Genet. Med. 3, 387-392.
-
(2001)
Genet. Med.
, vol.3
, pp. 387-392
-
-
Wang, Y.1
Korman, S.H.2
Ye, J.3
-
80
-
-
7144253130
-
Two frequent missense mutations in Pendred syndrome
-
Van Hauwe, P., Everett, L. A., Coucke, P., et al. (1998) Two frequent missense mutations in Pendred syndrome. Hum. Molec. Genet. 7, 1099-1104.
-
(1998)
Hum. Molec. Genet.
, vol.7
, pp. 1099-1104
-
-
Van Hauwe, P.1
Everett, L.A.2
Coucke, P.3
-
81
-
-
0033015606
-
Non-syndromic hearing loss associated with enlarged vestibular aqueduct is caused by PDS mutations
-
Usami, S., Abe, S., Weston, M. D., Shinkawa, H., Van Camp, G., and Kimberling, W. J. (1999) Non-syndromic hearing loss associated with enlarged vestibular aqueduct is caused by PDS mutations. Hum. Genet. 104, 188-192.
-
(1999)
Hum. Genet.
, vol.104
, pp. 188-192
-
-
Usami, S.1
Abe, S.2
Weston, M.D.3
Shinkawa, H.4
Van Camp, G.5
Kimberling, W.J.6
-
82
-
-
0026602751
-
Allelic variants of the human putative peptide transporter involved in antigen processing
-
Colonna, M., Bresnahan, M., Bahram, S., Strominger, J. L., and Spies, T. (1992) Allelic variants of the human putative peptide transporter involved in antigen processing. Proc. Nat. Acad. Sci. USA 89, 3932-3936.
-
(1992)
Proc. Nat. Acad. Sci. USA
, vol.89
, pp. 3932-3936
-
-
Colonna, M.1
Bresnahan, M.2
Bahram, S.3
Strominger, J.L.4
Spies, T.5
-
83
-
-
0034777332
-
Plasmodium falciparum pfcrt and pfmdr1 polymorphisms are associated with the pfdhfr N108 pyrimethamine-resistance mutation in isolates from Ghana
-
Mockenhaupt, F.P., Eggelte, T.A., Till, H., and Bienzle, U. (2001) Plasmodium falciparum pfcrt and pfmdr1 polymorphisms are associated with the pfdhfr N108 pyrimethamine-resistance mutation in isolates from Ghana. Trop. Med. Int. Health 6, 749-755.
-
(2001)
Trop. Med. Int. Health
, vol.6
, pp. 749-755
-
-
Mockenhaupt, F.P.1
Eggelte, T.A.2
Till, H.3
Bienzle, U.4
-
84
-
-
0035876910
-
Analysis of the key pfcrt point mutation and in vitro and in vivo response to chloroquine in Yaounde, Cameroon
-
Basco, L.K. and Ringwald, P. (2001) Analysis of the key pfcrt point mutation and in vitro and in vivo response to chloroquine in Yaounde, Cameroon. J. Infect. Dis. 183, 1828-1831.
-
(2001)
J. Infect. Dis.
, vol.183
, pp. 1828-1831
-
-
Basco, L.K.1
Ringwald, P.2
-
85
-
-
3042772026
-
Identification of functionally variant MDR1 alleles among European Americans and African Americans
-
Kim, R.B., Leake, B.F., Choo, E.F., et al. (2001) Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin. Pharmacol. Ther. 70, 189-199.
-
(2001)
Clin. Pharmacol. Ther.
, vol.70
, pp. 189-199
-
-
Kim, R.B.1
Leake, B.F.2
Choo, E.F.3
-
86
-
-
0035929574
-
Polymorphisms in OATP-C: Identification of multiple allelic variants associated with altered transport activity among European- and African-Americans
-
Tirana, R.G., Leake, B.F., Merino, G., and Kim, R.B. (2001) Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans. J. Biol. Chem. 276, 35669-35675.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35669-35675
-
-
Tirana, R.G.1
Leake, B.F.2
Merino, G.3
Kim, R.B.4
-
87
-
-
0032695572
-
Association of the dopamine transporter gene (DAT1) with poor methylphenidate response
-
Winsberg, B.G. and Comings, D.E. (1999) Association of the dopamine transporter gene (DAT1) with poor methylphenidate response. J. Am. Acad. Child Adolesc. Psychiatry 38, 1474-1477.
-
(1999)
J. Am. Acad. Child Adolesc. Psychiatry
, vol.38
, pp. 1474-1477
-
-
Winsberg, B.G.1
Comings, D.E.2
|