Efficient construction of a highly useful phage-displayed human antibody repertoire

Biochemical and Biophysical Research Communications

Volumn 336, Issue 4, 2005, Pages 1207-1213

  Rojas, Gertrudis ^a   Lamdan, Humberto ^a   Padron, Sheila ^a   Munoz, Yasmiana ^a   Ayala, Marta ^a   Gavilondo, Jorge V ^a  

^a CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

Author keywords

Antibody library; Phage display; Repertoire size

Indexed keywords

ANTIBODY;

ANTIBODY LIBRARY; ANTIGEN BINDING; ARTICLE; BACTERIOPHAGE; BINDING AFFINITY; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOCYTE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANTIGENS; HUMANS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOCYTES; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PROTEIN BINDING; SURFACE PLASMON RESONANCE;

EID: 25644448735     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.09.005     Document Type: Article

References (28)

1. H. de Haard, P. Henderikx, and H.R. Hoogenboom Creating and engineering human antibodies for immunotherapy Adv. Drug Delivery Rev. 31 1998 5 31
2. E. Rey, M. Zeidel, C. Rhine, J. Tami, K. Krolick, M. Fischbach, and I. Sanz Characterization of human anti-acetylcholine receptor monoclonal autoantibodies from the peripheral blood of a myasthenia gravis patient using combinatorial libraries Clin. Immunol. 96 2000 269 279
3. N. Reiche, A. Jung, T. Brabletz, T. Vater, T. Kirchner, and G. Faller Generation and characterization of human monoclonal scFv antibodies against Helicobacter pylori antigens Infect. Immunity 70 2002 4158 4164
4. J.D. Marks, H.R. Hoogenboom, T.P. Bonnert, J. McCafferty, A.D. Griffiths, and G. Winter By-passing immunization- human antibodies from V-gene libraries displayed on phage J. Mol. Biol. 222 1991 581 597
5. T.J. Vaughan, A.J. Williams, K. Pritchard, J.K. Osbourn, A.R. Pope, J.C. Earnshaw, J. McCafferty, R.A. Hodits, J. Wilton, and K.S. Johnson Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library Nat. Biotechnol. 14 1996 309 314
6. M.D. Sheets, P. Amersdorfer, R. Finnern, P. Saregent, E. Lindqvist, R. Schier, G. Hemingsen, C. Wong, J.C. Gerhart, and J.D. Marks Efficient construction of a large nonimmune phage antibody library: the production of high affinity human single-chain antibodies to protein antigens Proc. Natl. Acad. Sci. USA 95 1998 6157 6162
7. H. de Haard, N. van Neer, A. Reurs, S.E. Hufton, R.C. Roovers, P. Henderikx, A.P. de Bruine, J.-W. Arends, and H.R. Hoogenboom A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies J. Biol. Chem. 274 1999 18218 18230
8. D. Sblattero, and A. Bradbury Exploiting recombination in single bacteria to make large phage antibody libraries Nat. Biotechnol. 18 2000 75 80
9. D. Sblattero, J. Lou, R. Marzari, and A. Bradbury In vivo recombination as a tool to generate molecular diversity in phage antibody libraries Rev. Mol. Biotechnol. 74 2001 303 315
10. J. Lou, R. Marzari, V. Verzillo, F. Ferrero, D. Pak, M. Sheng, C. Yang, D. Sblattero, and A. Bradbury Antibodies in haystacks: how selection strategy influences the outcome of selection from molecular diversity libraries J. Immunol. Methods 253 2001 233 242
11. A. Knappik, L. Ge, A. Honegger, P. Pack, M. Fischer, G. Wellnhofer, A. Hoess, J. Wolle, A. Pluckthun, and B. Virnekas Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides J. Mol. Biol. 296 2000 57 86
12. M. Little, M. Welschof, M. Braunagel, I. Hermes, C. Christ, A. Keller, P. Rohrbach, T. Kurschner, S. Schmidt, C. Kleist, and P. Terness Generation of a complex antibody library from multiple donors J. Immunol. Methods 231 1999 3 9
13. T. Okamoto, Y. Mukai, Y. Yoshioka, H. Shibata, M. Kawamur, Y. Yamamoto, S. Nakagawa, H. Kamada, T. Hayakawa, T. Mayumi, and Y. Tsutsumi Optimal construction of non-immune scFv phage display libraries from mouse bone marrow and spleen established to select specific scFvs efficiently binding to antigen Biochem. Biophys. Res. Commun. 323 2004 583 591
14. G. Rojas, A. Talavera, Y. Munoz, E. Rengifo, U. Krengel, J. Angstrom, J.V. Gavilondo, and E. Moreno Light chain shuffling results in successful phage display selection of functional prokaryotic-expressed antibody fragments to N-glycolyl GM3 ganglioside J. Immunol. Methods 293 2004 71 83
15. P. Chames, R.A. Willemsen, G. Rojas, D. Dieckman, L. Rem, G. Schuler, R.L. Bolhuis, and H.R. Hoogenboom TCR-like human antibodies expressed on human CTLs mediate antibody affinity dependent cytolytic activity J. Immunol. 169 2002 1110 1118
16. P.D. Hodgkin Role of cross-reactivity in the development of antibody responses The Immunologist 6 1998 223 226
17. N.S. Greenspan Epitopes, paratopes and other topes: do immunologists know what they are talking about? Bull. Inst. Pasteur 90 1992 267 279
18. S.J. Smith-Gill Protein epitopes: functional vs. structural definitions Res. Immunol. 145 1994 67 70
19. D.M. Webster, A.H. Henry, and A.R. Rees Antibody-antigen interactions Curr. Opin. Struct. Biol. 4 1994 123 129
20. P.M. Colman Effects of amino acid changes on antibody-antigen interactions Res. Immunol. 145 1994 33 36
21. G.A. Bentley, G. Boulot, and V. Chitarra Cross-reactivity in antibody-antigen interactions Res. Immunol. 145 1994 45 48
22. M. Cohn The wisdom of hindsight Annu. Rev. Immunol. 12 1994 1 62
23. J.E. Butler Immunoglobulin gene organization and the mechanism of repertoire development: a review Scand. J. Immunol. 45 1997 269 276
24. T. Ota, T. Sitnikova, and M. Nei Evolution of vertebrate immunoglobulin variable gene segments Curr. Top. Microbiol. Immunol. 248 2000 221 245
25. M. Ohlin, and C.A.K. Borrebaeck Characteristics of human antibody repertoires following active immune responses in vivo Mol. Immunol. 33 1996 583 592
26. R.M.T. de Wildt, C.R. Mundy, B.D. Gorick, and I.M. Tomlinson Antibody arrays for high throughput screening of antibody-antigen interactions Nat. Biotechnol. 18 2000 989 994
27. Z. Konthur, and G. Walter Automation of phage display for high throughput antibody development Targets 1 2002 30 36
28. J. Hallborn, and J.R. Carlsson Automated screening procedure for high-throughput generation of antibody fragments BioTechniques 33 2002 S30 S37