Optimal construction of non-immune scFv phage display libraries from mouse bone marrow and spleen established to select specific scFvs efficiently binding to antigen

Biochemical and Biophysical Research Communications

Volumn 323, Issue 2, 2004, Pages 583-591

  Okamoto, Takayuki ^a   Mukai, Yohei ^a   Yoshioka, Yasuo ^a,b   Shibata, Hiroko ^a   Kawamura, Maki ^a   Yamamoto, Yoko ^a   Nakagawa, Shinsaku ^a   Kamada, Haruhiko ^c   Hayakawa, Takao ^b   Mayumi, Tadanori ^b   Tsutsumi, Yasuo ^a,c  

^a OSAKA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c KOBE GAKUIN UNIVERSITY   (Japan)

Author keywords

Antibody therapy; Non immune library; Phage display system

Indexed keywords

MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY LIBRARY; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; GENE LIBRARY; IMMUNIZATION; MOLECULAR CLONING; MOUSE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY COMPLEX; BACTERIOPHAGES; BONE MARROW; CELLS, CULTURED; CLONING, MOLECULAR; DRUG DESIGN; IMMUNOASSAY; IMMUNOGLOBULIN VARIABLE REGION; MALE; MICE; MICE, INBRED C57BL; PEPTIDE LIBRARY; POLYMERASE CHAIN REACTION; PROTEIN ENGINEERING; SPLEEN;

ANIMALIA; PSEUDOMONAS;

EID: 4544239030     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.08.131     Document Type: Article

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