메뉴 건너뛰기




Volumn 33, Issue 7-8, 1996, Pages 583-592

Characteristics of human antibody repertoires following active immune responses in vivo

Author keywords

antibody variable domain; germline gene usage; human monoclonal antibodies; J segment; phage display; somatic mutation; T cell dependent antibody response; V segment

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY;

EID: 0030152049     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/0161-5890(96)00018-1     Document Type: Note
Times cited : (49)

References (77)
  • 1
    • 0025868277 scopus 로고
    • Molecular characterization of five human anti-human immunodeficiency virus type 1 antibody heavy chains reveals extensive somatic mutation typical of an antigen-driven immune response
    • Andris J. S., Johnson S., Zolla-Pazner S. and Capra J. D. (1991) Molecular characterization of five human anti-human immunodeficiency virus type 1 antibody heavy chains reveals extensive somatic mutation typical of an antigen-driven immune response. Proc. natn. Acad. Sci. U.S.A. 88, 7783-7787.
    • (1991) Proc. Natn. Acad. Sci. U.S.A. , vol.88 , pp. 7783-7787
    • Andris, J.S.1    Johnson, S.2    Zolla-Pazner, S.3    Capra, J.D.4
  • 2
    • 0027095905 scopus 로고
    • Probing the human antibody repertoire to exogenous antigens. Characterization of the H and L chain V region gene segments from anti-hepatitis B virus antibodies
    • Andris J. S., Ehrlich P. H., Östberg L. and Capra J. D. (1992) Probing the human antibody repertoire to exogenous antigens. Characterization of the H and L chain V region gene segments from anti-hepatitis B virus antibodies. J. Immun. 149, 4053-5059.
    • (1992) J. Immun. , vol.149 , pp. 4053-5059
    • Andris, J.S.1    Ehrlich, P.H.2    Östberg, L.3    Capra, J.D.4
  • 3
    • 0027131399 scopus 로고
    • Molecular characterization of human antbodies to bacterial antigens: Utilization of the less frequently expressed VH2 and VH6 heavy chain variable region gene families
    • Andris J. S., Brodeur B. R. and Capra J. D. (1993) Molecular characterization of human antbodies to bacterial antigens: utilization of the less frequently expressed VH2 and VH6 heavy chain variable region gene families. Molec. Immun. 30, 1601-1616.
    • (1993) Molec. Immun. , vol.30 , pp. 1601-1616
    • Andris, J.S.1    Brodeur, B.R.2    Capra, J.D.3
  • 4
    • 0027272719 scopus 로고
    • The natural autoantibodies system: Between hypotheses and facts
    • Avrameas S. and Ternynck T. (1993) The natural autoantibodies system: between hypotheses and facts. Molec. Immun. 30, 1133-1142.
    • (1993) Molec. Immun. , vol.30 , pp. 1133-1142
    • Avrameas, S.1    Ternynck, T.2
  • 5
    • 0027173996 scopus 로고
    • Sequence determination of variable region genes of two human monoclonal antibodies against Neisseria meningitidis
    • Ayala Avila M., Vazques J., Danielsson L., Fernández de Cossio M. E. and Borrebaeck C. A. K. (1993) Sequence determination of variable region genes of two human monoclonal antibodies against Neisseria meningitidis. Gene 127, 273-274.
    • (1993) Gene , vol.127 , pp. 273-274
    • Ayala Avila, M.1    Vazques, J.2    Danielsson, L.3    Fernández De Cossio, M.E.4    Borrebaeck, C.A.K.5
  • 6
    • 0028001662 scopus 로고
    • Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120
    • Bagley J., Dillon P. J., Rosen C., Robinson J., Sodroski J. and Marasco W. A. (1994) Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120. Molec. Immun. 31, 1149-1160.
    • (1994) Molec. Immun. , vol.31 , pp. 1149-1160
    • Bagley, J.1    Dillon, P.J.2    Rosen, C.3    Robinson, J.4    Sodroski, J.5    Marasco, W.A.6
  • 8
  • 10
    • 84974752904 scopus 로고
    • Human monoclonal Fab fragments from a combinatorial library prepared from an individual with a low serum titer to a virus
    • Bender E., Pilkington G. R. and Burton D. R. (1994) Human monoclonal Fab fragments from a combinatorial library prepared from an individual with a low serum titer to a virus. Human Antibod. Hybrid. 5, 3-8.
    • (1994) Human Antibod. Hybrid. , vol.5 , pp. 3-8
    • Bender, E.1    Pilkington, G.R.2    Burton, D.R.3
  • 11
    • 0027340737 scopus 로고
    • Immunoglobulin VH3 gene products: Natural ligands for HIV gp120
    • Berberian L., Goodglick L., Kipps T. J. and Braun J. (1993) Immunoglobulin VH3 gene products: natural ligands for HIV gp120. Science 261, 1588-1591.
    • (1993) Science , vol.261 , pp. 1588-1591
    • Berberian, L.1    Goodglick, L.2    Kipps, T.J.3    Braun, J.4
  • 13
    • 0028082433 scopus 로고
    • Recombinant human Fab to glycoprotein D neutralizes infectivity and prevents cell-to-cell transmission of herpes simplex viruses 1 and 2 in vitro
    • Burioni R., Williamson R. A., Sanna P. S., Bloom F. E. and Burton D. R. (1994) Recombinant human Fab to glycoprotein D neutralizes infectivity and prevents cell-to-cell transmission of herpes simplex viruses 1 and 2 in vitro. Proc. natn. Acad. Sci. U.S.A. 91, 355-359.
    • (1994) Proc. Natn. Acad. Sci. U.S.A. , vol.91 , pp. 355-359
    • Burioni, R.1    Williamson, R.A.2    Sanna, P.S.3    Bloom, F.E.4    Burton, D.R.5
  • 14
    • 0026672681 scopus 로고
    • A recombinant human Fab expressed in Escherichia coli neutralizes rabies virus
    • Cheung S. C., Dietzschold B., Koprowski H., Notkins A. L. and Rando R. F. (1992) A recombinant human Fab expressed in Escherichia coli neutralizes rabies virus. J. Virol. 66, 6714-6720.
    • (1992) J. Virol. , vol.66 , pp. 6714-6720
    • Cheung, S.C.1    Dietzschold, B.2    Koprowski, H.3    Notkins, A.L.4    Rando, R.F.5
  • 16
    • 0025730554 scopus 로고
    • V lambda and J lambda-C lambda gene segments of the human immunoglobulin lambda light chain locus are separated by 14kb and rearrange by a deletion mechanism
    • Combriato G. and Klobeck H-G. (1991) V lambda and J lambda-C lambda gene segments of the human immunoglobulin lambda light chain locus are separated by 14kb and rearrange by a deletion mechanism. Eur. J. Immun. 21, 1513-1522.
    • (1991) Eur. J. Immun. , vol.21 , pp. 1513-1522
    • Combriato, G.1    Klobeck, H.-G.2
  • 17
    • 0028986982 scopus 로고
    • The human immunoglobulin VH repertoire
    • Cook G. P. and Tomlinson I. M. (1995) The human immunoglobulin VH repertoire. Immun. Today 16, 237-242.
    • (1995) Immun. Today , vol.16 , pp. 237-242
    • Cook, G.P.1    Tomlinson, I.M.2
  • 18
    • 0028326520 scopus 로고
    • A directory of human germ-line Vκ segments reveals a strong bias in their usage
    • Cox J. P. L., Tomlinson I. M. and Winter G. (1994) A directory of human germ-line Vκ segments reveals a strong bias in their usage. Eur. J. Immun. 24, 826-827.
    • (1994) Eur. J. Immun. , vol.24 , pp. 826-827
    • Cox, J.P.L.1    Tomlinson, I.M.2    Winter, G.3
  • 19
    • 0029093328 scopus 로고
    • Molecular characterization of human monoclonal antibodies specific for several HIV proteins: Analysis of VH3 family expression
    • David D., Goossens D., Desgranges C., Thèze J. and Zouali M. (1995) Molecular characterization of human monoclonal antibodies specific for several HIV proteins: analysis of VH3 family expression. Immun. Lett. 47, 107-112.
    • (1995) Immun. Lett. , vol.47 , pp. 107-112
    • David, D.1    Goossens, D.2    Desgranges, C.3    Thèze, J.4    Zouali, M.5
  • 20
    • 0028817452 scopus 로고
    • Variable region light chain genes encoding human antibodies to HIV-1
    • David D. and Zouali M. (1995) Variable region light chain genes encoding human antibodies to HIV-1. Molec. Immun. 32, 77-88.
    • (1995) Molec. Immun. , vol.32 , pp. 77-88
    • David, D.1    Zouali, M.2
  • 21
    • 0027209976 scopus 로고
    • Properties of a human monoclonal antibody specific for the NS4 region of hepatitis C virus
    • de Lalla C., Cerino A., Rosa C., Griva S., Bonelli F. and Mondelli M. U. (1993) Properties of a human monoclonal antibody specific for the NS4 region of hepatitis C virus. J. Hepatol. 18, 163-167.
    • (1993) J. Hepatol. , vol.18 , pp. 163-167
    • De Lalla, C.1    Cerino, A.2    Rosa, C.3    Griva, S.4    Bonelli, F.5    Mondelli, M.U.6
  • 23
    • 0028831142 scopus 로고
    • Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure
    • Ditzel H. J., Binley J. M., Moore J. P., Sodroski J., Sullivan N., Sawyer L. S. W., Hendry R. M., Yang W-P., Barbas III C.F. and Burton D. R. (1995) Neutralizing recombinant human antibodies to a conformational V2-and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure. J. Immun. 154, 893-906.
    • (1995) J. Immun. , vol.154 , pp. 893-906
    • Ditzel, H.J.1    Binley, J.M.2    Moore, J.P.3    Sodroski, J.4    Sullivan, N.5    Sawyer, L.S.W.6    Hendry, R.M.7    Yang, W.-P.8    Barbas C.F. III9    Burton, D.R.10
  • 24
    • 0029017297 scopus 로고
    • A point mutation in a murine immunoglobulin V-region strongly influence antibody yield in Escherichia coli
    • Dueñas M., Ayala M., Vázquez J., Ohlin M., Söderlind E., Borrebaeck C. A. K. and Gavilondo J. V. (1995) A point mutation in a murine immunoglobulin V-region strongly influence antibody yield in Escherichia coli. Gene 158, 61-66.
    • (1995) Gene , vol.158 , pp. 61-66
    • Dueñas, M.1    Ayala, M.2    Vázquez, J.3    Ohlin, M.4    Söderlind, E.5    Borrebaeck, C.A.K.6    Gavilondo, J.V.7
  • 25
    • 0028787062 scopus 로고
    • A human antibody specific for hepatitis C virus core protein: Synthesis in a bacterial system and characterization
    • Esposito G., Scarcelli E., Cerino A., Mondelli M. U., La Monica N. and Traboni C. (1995) A human antibody specific for hepatitis C virus core protein: synthesis in a bacterial system and characterization. Gene 164, 203-209.
    • (1995) Gene , vol.164 , pp. 203-209
    • Esposito, G.1    Scarcelli, E.2    Cerino, A.3    Mondelli, M.U.4    La Monica, N.5    Traboni, C.6
  • 26
    • 0027999656 scopus 로고
    • Phage display of a human antibody against Clostridium tetani toxin
    • Esposito G., Scarcelli E. and Traboni C. (1994) Phage display of a human antibody against Clostridium tetani toxin. Gene 148, 167-168.
    • (1994) Gene , vol.148 , pp. 167-168
    • Esposito, G.1    Scarcelli, E.2    Traboni, C.3
  • 27
    • 0025160356 scopus 로고
    • Nucleotide sequences of the cDNAs encoding the V-regions of H- and L-chains of a human monoclonal antibody specific for HIV-1-gp41
    • Felgenhauer M. and Kohl J., Ruker F. (1990) Nucleotide sequences of the cDNAs encoding the V-regions of H-and L-chains of a human monoclonal antibody specific for HIV-1-gp41. Nucl. Acids Res. 18, 4927.
    • (1990) Nucl. Acids Res. , vol.18 , pp. 4927
    • Felgenhauer, M.1    Kohl, J.2    Ruker, F.3
  • 28
    • 0027943261 scopus 로고
    • Conformational isomerism and the diversity of antibodies
    • Foote J. and Milstein C. (1994) Conformational isomerism and the diversity of antibodies. Proc. natn. Acad. Sci. U.S.A. 91, 10370-10374.
    • (1994) Proc. Natn. Acad. Sci. U.S.A. , vol.91 , pp. 10370-10374
    • Foote, J.1    Milstein, C.2
  • 30
    • 0028929284 scopus 로고
    • Molecular mimicry, anti-coxsackievirus B3 neutralizing monoclonal antibodies, and myocarditis
    • Gauntt C. J., Arizpe H. M., Higdon A. L., Wood H. J., Bowers D. F., Rozek M. M. and Crawley R. (1995) Molecular mimicry, anti-coxsackievirus B3 neutralizing monoclonal antibodies, and myocarditis. J. immun. 154, 2983-2995.
    • (1995) J. Immun. , vol.154 , pp. 2983-2995
    • Gauntt, C.J.1    Arizpe, H.M.2    Higdon, A.L.3    Wood, H.J.4    Bowers, D.F.5    Rozek, M.M.6    Crawley, R.7
  • 32
    • 0028352311 scopus 로고
    • Revenge of the microbes. Superantigens of the T and B cell lineage
    • Goodglick L. and Braun J. (1994) Revenge of the microbes. Superantigens of the T and B cell lineage. Am. J. Pathol. 144, 623-636.
    • (1994) Am. J. Pathol. , vol.144 , pp. 623-636
    • Goodglick, L.1    Braun, J.2
  • 33
    • 0028856065 scopus 로고
    • Mapping the Ig superantigen-binding site of HIV-1 gp 120
    • Goodglick L., Zevit N., Neshat M. S. and Braun J. (1995) Mapping the Ig superantigen-binding site of HIV-1 gp 120. J. Immun. 155, 5151-5159.
    • (1995) J. Immun. , vol.155 , pp. 5151-5159
    • Goodglick, L.1    Zevit, N.2    Neshat, M.S.3    Braun, J.4
  • 36
    • 0026522087 scopus 로고
    • Variable gene usage, physiology and development of Ly-1+ (CD5+) B cells
    • Hardy R. R. (1992) Variable gene usage, physiology and development of Ly-1+ (CD5+) B cells. Curr. Opin. Immun. 4, 181-185.
    • (1992) Curr. Opin. Immun. , vol.4 , pp. 181-185
    • Hardy, R.R.1
  • 37
    • 84974756271 scopus 로고
    • A human monoclonal antbody with the capacity to neutralize Staphylococcus aureus alpha-toxin
    • Heveker N., Hansen A., Hungerer K-D., von Baehr R. and Glaser R. W. (1994) A human monoclonal antbody with the capacity to neutralize Staphylococcus aureus alpha-toxin. Human Antibod. Hybrid. 5, 18-24.
    • (1994) Human Antibod. Hybrid. , vol.5 , pp. 18-24
    • Heveker, N.1    Hansen, A.2    Hungerer, K.-D.3    Von Baehr, R.4    Glaser, R.W.5
  • 38
    • 0027050981 scopus 로고
    • Sequence analyses of three immunoglobulin G anti-virus antibodies reveal their utilization of autoantibody-related immunoglobulin Vh genes, but not Vλ genes
    • Huang D.-F., Olee T., Masuho Y., Matsumoto Y.-I, Carson D. A. and Chen P. P. (1992) Sequence analyses of three immunoglobulin G anti-virus antibodies reveal their utilization of autoantibody-related immunoglobulin Vh genes, but not Vλ genes. J. clin. Invest. 90, 2197-2208.
    • (1992) J. Clin. Invest. , vol.90 , pp. 2197-2208
    • Huang, D.-F.1    Olee, T.2    Masuho, Y.3    Matsumoto, Y.-I.4    Carson, D.A.5    Chen, P.P.6
  • 39
    • 0028101448 scopus 로고
    • Analysis of the structural correlates for antibody polyreactivity by multiple reassortments of chimeric human immunoglobulin heavy and light chain V segments
    • Ichiyoshi Y. and Casali P. (1994) Analysis of the structural correlates for antibody polyreactivity by multiple reassortments of chimeric human immunoglobulin heavy and light chain V segments. J. exp. Med. 180, 885-895.
    • (1994) J. Exp. Med. , vol.180 , pp. 885-895
    • Ichiyoshi, Y.1    Casali, P.2
  • 40
    • 0027275899 scopus 로고
    • Clonal analysis of a human antibody response. II. Sequences of the VH genes of human IgM, IgG and IgA to rabies virus reveal preferential utilization of VHIII segments and somatic hypermutation
    • Ikematsu H., Harindranath N., Ueki Y., Notkins A. L. and Casali P. (1993) Clonal analysis of a human antibody response. II. Sequences of the VH genes of human IgM, IgG and IgA to rabies virus reveal preferential utilization of VHIII segments and somatic hypermutation. J. Immun. 150, 1325-1337.
    • (1993) J. Immun. , vol.150 , pp. 1325-1337
    • Ikematsu, H.1    Harindranath, N.2    Ueki, Y.3    Notkins, A.L.4    Casali, P.5
  • 41
    • 0027428398 scopus 로고
    • Expressed human immunoglobulin κ genes and their hypermutation
    • Klein R., Jaenichen R. and Zachau H. G. (1993) Expressed human immunoglobulin κ genes and their hypermutation. Eur. J. Immun. 23, 3248-3271.
    • (1993) Eur. J. Immun. , vol.23 , pp. 3248-3271
    • Klein, R.1    Jaenichen, R.2    Zachau, H.G.3
  • 42
    • 0027484057 scopus 로고
    • Human rheumatoid factor cross-idiotypes. IV. Studies on WA Xld-positive IgM without rheumatoid factor activity provide evidence that the WA Xld is not unique to rheumatoid factors and is distinct from the 17.109 and G6 ilds
    • Knight G. B., Agnello V., Bonagura V., Barnes J. L., Panka D. J. and Zhang Q.-X. (1993) Human rheumatoid factor cross-idiotypes. IV. Studies on WA Xld-positive IgM without rheumatoid factor activity provide evidence that the WA Xld is not unique to rheumatoid factors and is distinct from the 17.109 and G6 Ilds. J. exp. Med. 178, 1903-1911.
    • (1993) J. Exp. Med. , vol.178 , pp. 1903-1911
    • Knight, G.B.1    Agnello, V.2    Bonagura, V.3    Barnes, J.L.4    Panka, D.J.5    Zhang, Q.-X.6
  • 43
    • 0029029375 scopus 로고
    • Evidence for the overexpression of the VH4-34 (VH4.21) Ig gene segment in the normal adult human peripheral blood B cell repertoire
    • Kraj P., Friedman D. F., Stevenson F. and Silberstein L. E. (1995) Evidence for the overexpression of the VH4-34 (VH4.21) Ig gene segment in the normal adult human peripheral blood B cell repertoire. J. Immun. 154, 6406-6420.
    • (1995) J. Immun. , vol.154 , pp. 6406-6420
    • Kraj, P.1    Friedman, D.F.2    Stevenson, F.3    Silberstein, L.E.4
  • 44
    • 0029132603 scopus 로고
    • Single, antigen-specific B cells used to generate Fab fragments using CD40-mediated amplification or direct PCR cloning
    • Lagerkvist A. C. S., Furebring C. and Borrebaeck C. A. K. (1995) Single, antigen-specific B cells used to generate Fab fragments using CD40-mediated amplification or direct PCR cloning. BioTechniques 18, 862-869.
    • (1995) BioTechniques , vol.18 , pp. 862-869
    • Lagerkvist, A.C.S.1    Furebring, C.2    Borrebaeck, C.A.K.3
  • 45
    • 0027008598 scopus 로고
    • Therapeutic human antibodies derived from PCR amplification of B-cell variable regions
    • Larrick J. W., Wallace E. F., Coloma M. J., Bruderer U., Lang A. B. and Fry K. E. (1992) Therapeutic human antibodies derived from PCR amplification of B-cell variable regions. Immun. Rev. 130, 69-85.
    • (1992) Immun. Rev. , vol.130 , pp. 69-85
    • Larrick, J.W.1    Wallace, E.F.2    Coloma, M.J.3    Bruderer, U.4    Lang, A.B.5    Fry, K.E.6
  • 47
    • 0024677521 scopus 로고
    • Frequency of VH-gene utilization in human EBV-transformed B cell lines: The most JH-proximal VH segment encodes autoantibodies
    • Logtenberg T., Young F. M., van Es J., Gmelig-Meyling F. H. J., Berman J. E. and Alt F. W. (1989) Frequency of VH-gene utilization in human EBV-transformed B cell lines: the most JH-proximal VH segment encodes autoantibodies. J. Autoimmun. 2 (suppl.), 203-213.
    • (1989) J. Autoimmun. , vol.2 , Issue.SUPPL. , pp. 203-213
    • Logtenberg, T.1    Young, F.M.2    Van Es, J.3    Gmelig-Meyling, F.H.J.4    Berman, J.E.5    Alt, F.W.6
  • 48
    • 0022526892 scopus 로고
    • Restricted light chain subgroup expression on human rheumatoid factor paraproteins determined by monoclonal antibodies
    • Mageed R. A., Walker M. R. and Jefferis R. (1986) Restricted light chain subgroup expression on human rheumatoid factor paraproteins determined by monoclonal antibodies. Immunology 59, 473-478.
    • (1986) Immunology , vol.59 , pp. 473-478
    • Mageed, R.A.1    Walker, M.R.2    Jefferis, R.3
  • 49
  • 50
    • 0028225961 scopus 로고
    • Significance of the immune response to a major, conformational B cell epitope on the hepatitis C virus NS3 region defined by a human monoclonal antibody
    • Mondelli M. U., Cerino A., Boender P., Oudshoorn P., Middeldorp J., Fipaldini C., La Monica N. and Habets W. (1994) Significance of the immune response to a major, conformational B cell epitope on the hepatitis C virus NS3 region defined by a human monoclonal antibody. J. Virol. 68, 4829-4836.
    • (1994) J. Virol. , vol.68 , pp. 4829-4836
    • Mondelli, M.U.1    Cerino, A.2    Boender, P.3    Oudshoorn, P.4    Middeldorp, J.5    Fipaldini, C.6    La Monica, N.7    Habets, W.8
  • 51
    • 0027367543 scopus 로고
    • Variable region genes of anti-HIV human monoclonal antibodies: Non-restricted use of the V gene repertoire and extensive mutation
    • Moran M. J., Andris J. S., Matsumato Y.-I., Capra D. and Hersh E. M. (1993) Variable region genes of anti-HIV human monoclonal antibodies: non-restricted use of the V gene repertoire and extensive mutation. Molec. Immun. 30, 1543-1551.
    • (1993) Molec. Immun. , vol.30 , pp. 1543-1551
    • Moran, M.J.1    Andris, J.S.2    Matsumato, Y.-I.3    Capra, D.4    Hersh, E.M.5
  • 53
    • 0024005429 scopus 로고
    • Complete protein sequences of the variable regions of the cloned heavy and light chains of a human anti-cytomegalovirus antibody reveal a striking similarity to human monoclonal rheumatoid factors of the Wa idiotypic family
    • Newkirk M. M., Gram H., Heinrich G. F., Östberg L., Capra J. D. and Wasserman R. L. (1988) Complete protein sequences of the variable regions of the cloned heavy and light chains of a human anti-cytomegalovirus antibody reveal a striking similarity to human monoclonal rheumatoid factors of the Wa idiotypic family. J. clin. Invest. 81, 1511-1518.
    • (1988) J. Clin. Invest. , vol.81 , pp. 1511-1518
    • Newkirk, M.M.1    Gram, H.2    Heinrich, G.F.3    Östberg, L.4    Capra, J.D.5    Wasserman, R.L.6
  • 54
    • 0027453098 scopus 로고
    • Restricted immunoglobulin variable region usage by hybridoma rheumatoid factors from patients with systemic lupus erythematosus and rheumatoid arthritis
    • Newkirk M. M., Rauch J., Mageed R. A. K., Jefferis R., Posnett D. N. and Silverman G. J. (1993) Restricted immunoglobulin variable region usage by hybridoma rheumatoid factors from patients with systemic lupus erythematosus and rheumatoid arthritis. Molec. Immun. 30, 255-263.
    • (1993) Molec. Immun. , vol.30 , pp. 255-263
    • Newkirk, M.M.1    Rauch, J.2    Mageed, R.A.K.3    Jefferis, R.4    Posnett, D.N.5    Silverman, G.J.6
  • 55
    • 0029981792 scopus 로고    scopus 로고
    • Light chain shuffling of a high affinity antibody results in a drift in epitope recognition
    • Ohlin M., Owman H., Mach M. and Borrebaeck C. A. K. (1996) Light chain shuffling of a high affinity antibody results in a drift in epitope recognition. Molec. Immun. 33, 47-56.
    • (1996) Molec. Immun. , vol.33 , pp. 47-56
    • Ohlin, M.1    Owman, H.2    Mach, M.3    Borrebaeck, C.A.K.4
  • 56
    • 0028074342 scopus 로고
    • Restricted variable region gene usage and possible rheumatoid factor relationship among human monoclonal antibodies specific for the AD-1 epitope on cytomegalovirus glycoprotein B
    • Ohlin M., Owman H., Rioux J. D., Newkirk M. M. and Borrebaeck C. A. K. (1994) Restricted variable region gene usage and possible rheumatoid factor relationship among human monoclonal antibodies specific for the AD-1 epitope on cytomegalovirus glycoprotein B. Molec. Immun. 31, 983-991.
    • (1994) Molec. Immun. , vol.31 , pp. 983-991
    • Ohlin, M.1    Owman, H.2    Rioux, J.D.3    Newkirk, M.M.4    Borrebaeck, C.A.K.5
  • 57
    • 0025620796 scopus 로고
    • Heavy chain variable region gene utilization in human antibodies
    • Pascual V., Andris J. and Capra J. D. (1990) Heavy chain variable region gene utilization in human antibodies. Int. Rev. Immun. 5, 231-238.
    • (1990) Int. Rev. Immun. , vol.5 , pp. 231-238
    • Pascual, V.1    Andris, J.2    Capra, J.D.3
  • 58
    • 0028980901 scopus 로고
    • Combinatorial libraries: New insights into human organ-specific autoantibodies
    • Rapoport B., Portolano S. and McLachlan S. M. (1995) Combinatorial libraries: new insights into human organ-specific autoantibodies. Immun. Today 16, 43-49.
    • (1995) Immun. Today , vol.16 , pp. 43-49
    • Rapoport, B.1    Portolano, S.2    McLachlan, S.M.3
  • 59
    • 0028306645 scopus 로고
    • Structural characteristics of four human hybridoma antibodies specific for the pp65 protein of the human cytomegalovirus and their relationship to human rheumatoid factors
    • Rioux J. D., Larose Y., Brodeur B. R., Radzioch D. and Newkirk M. M. (1994) Structural characteristics of four human hybridoma antibodies specific for the pp65 protein of the human cytomegalovirus and their relationship to human rheumatoid factors. Molec. Immun. 31, 585-597.
    • (1994) Molec. Immun. , vol.31 , pp. 585-597
    • Rioux, J.D.1    Larose, Y.2    Brodeur, B.R.3    Radzioch, D.4    Newkirk, M.M.5
  • 60
    • 0029105358 scopus 로고
    • Molecular characterization of human monoclonal antibodies specific for the human cytomegalovirus: Relationship of variable region sequence to antigen specificity and rheumatoid factor-associated
    • Rioux J. D., Ohlin M., Borrebaeck C. A. K. and Newkirk M. M. (1995) Molecular characterization of human monoclonal antibodies specific for the human cytomegalovirus: relationship of variable region sequence to antigen specificity and rheumatoid factor-associated. Immun. Infect. Dis. 5, 43-52.
    • (1995) Immun. Infect. Dis. , vol.5 , pp. 43-52
    • Rioux, J.D.1    Ohlin, M.2    Borrebaeck, C.A.K.3    Newkirk, M.M.4
  • 61
    • 0028068381 scopus 로고
    • A human rheumatoid factor C304 shares VH and VL gene usage with antibodies specific for ubiquitous human viral pathogens
    • Rioux J. D., Rauch J., Silvestri L. and Newkirk M. M. (1994) A human rheumatoid factor C304 shares VH and VL gene usage with antibodies specific for ubiquitous human viral pathogens. Scand. J. Immun. 40, 350-354.
    • (1994) Scand. J. Immun. , vol.40 , pp. 350-354
    • Rioux, J.D.1    Rauch, J.2    Silvestri, L.3    Newkirk, M.M.4
  • 62
    • 0029073302 scopus 로고
    • Directed selection of recombinant human monoclonal antibodies to herpes simplex virus glycoproteins from phage display libraries
    • Sanna P. P., Williamson R. A., De Logu A., Bloom F. E. and Burton D. R. (1995) Directed selection of recombinant human monoclonal antibodies to herpes simplex virus glycoproteins from phage display libraries. Proc. natn. Acad. Sci. U.S.A. 92, 6439-6443
    • (1995) Proc. Natn. Acad. Sci. U.S.A. , vol.92 , pp. 6439-6443
    • Sanna, P.P.1    Williamson, R.A.2    De Logu, A.3    Bloom, F.E.4    Burton, D.R.5
  • 65
    • 0002410325 scopus 로고
    • Superantigens and the spectrum of unconventional B-cell antigens
    • Silverman G. J. (1994) Superantigens and the spectrum of unconventional B-cell antigens. The Immunologist 2, 51-57.
    • (1994) The Immunologist , vol.2 , pp. 51-57
    • Silverman, G.J.1
  • 66
    • 0028915995 scopus 로고
    • Two-phase approach for the expression of high-affinity human anti-human immunodeficiency virus immunoglobulin Fab domains in Escherichia coli
    • Takeda S., Dorfman N. A., Robert-Guroff M., Notkins A. L. and Rando R. F. (1995) Two-phase approach for the expression of high-affinity human anti-human immunodeficiency virus immunoglobulin Fab domains in Escherichia coli. Hybridoma 14, 9-18.
    • (1995) Hybridoma , vol.14 , pp. 9-18
    • Takeda, S.1    Dorfman, N.A.2    Robert-Guroff, M.3    Notkins, A.L.4    Rando, R.F.5
  • 67
    • 0028107057 scopus 로고
    • Variable region gene usage of human monoclonal rheumatoid factors derived from healthy donors following immunization
    • Thompson K. M., Randen I., Børretzen M., Førre Ø. and Natvig J. B. (1994) Variable region gene usage of human monoclonal rheumatoid factors derived from healthy donors following immunization. Eur. J. Immun. 24, 1771-1778.
    • (1994) Eur. J. Immun. , vol.24 , pp. 1771-1778
    • Thompson, K.M.1    Randen, I.2    Børretzen, M.3    Førre, Ø.4    Natvig, J.B.5
  • 68
    • 0026785856 scopus 로고
    • The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops
    • Tomlinson I. M., Walter G., Marks J. D., Llewelyn M. B. and Winter G. (1992) The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops. J. molec. Biol. 227, 776-798.
    • (1992) J. Molec. Biol. , vol.227 , pp. 776-798
    • Tomlinson, I.M.1    Walter, G.2    Marks, J.D.3    Llewelyn, M.B.4    Winter, G.5
  • 69
    • 0029610794 scopus 로고
    • Canonical structures repertoire of the antigen-binding site of immunoglobulin suggests strong geometrical restrictions associated to the mechanism of immune recognition
    • Vargas-Madrazo E., Lara-Ochoa F. and Almagro J. C. (1995) Canonical structures repertoire of the antigen-binding site of immunoglobulin suggests strong geometrical restrictions associated to the mechanism of immune recognition. J. molec. Biol. 254, 497-504.
    • (1995) J. Molec. Biol. , vol.254 , pp. 497-504
    • Vargas-Madrazo, E.1    Lara-Ochoa, F.2    Almagro, J.C.3
  • 70
    • 0028068414 scopus 로고
    • Staphylococcal protein A induces biased production of Ig by VH3-expressing B lymphocytes
    • Vasquez Kristiansen S., Pascual V. and Lipsky P. E. (1994) Staphylococcal protein A induces biased production of Ig by VH3-expressing B lymphocytes. J. Immun. 153, 2974-2982.
    • (1994) J. Immun. , vol.153 , pp. 2974-2982
    • Vasquez Kristiansen, S.1    Pascual, V.2    Lipsky, P.E.3
  • 71
    • 0028609273 scopus 로고
    • Molecular characterization of variable heavy and light chain regions of five HIV type 1-specific human monoclonal antibodies
    • van der Donk E. M. M., Schutten M., Osterhaus A.D.M.E., van der Heijden R. W. J. (1994) Molecular characterization of variable heavy and light chain regions of five HIV type 1-specific human monoclonal antibodies. AIDS Res. hum. Retrovir. 10, 1639-1649
    • (1994) AIDS Res. Hum. Retrovir. , vol.10 , pp. 1639-1649
    • Van Der Donk, E.M.M.1    Schutten, M.2    Osterhaus, A.D.M.E.3    Van Der Heijden, R.W.J.4
  • 72
    • 0026275206 scopus 로고
    • Some cautionary notes on interpreting immunoglobulin variable gene segment restriction in autoimmune disease
    • Edited by Bigazzi P. E. and Reichlin M. Marcel Dekker Inc., New York
    • Victor K., Andris J., Pascual V. and Capra J. D. (1991) Some cautionary notes on interpreting immunoglobulin variable gene segment restriction in autoimmune disease. In Systemic Autoimmunity (Edited by Bigazzi P. E. and Reichlin M.), pp. 1-12. Marcel Dekker Inc., New York.
    • (1991) Systemic Autoimmunity , pp. 1-12
    • Victor, K.1    Andris, J.2    Pascual, V.3    Capra, J.D.4
  • 73
    • 0027201551 scopus 로고
    • Cloning and sequencing of human immunoglobulin Vλ gene segments
    • Williams S. C. and Winter G. (1993) Cloning and sequencing of human immunoglobulin Vλ gene segments. Eur. J. Immun. 23, 1456-1461.
    • (1993) Eur. J. Immun. , vol.23 , pp. 1456-1461
    • Williams, S.C.1    Winter, G.2
  • 75
    • 0026099589 scopus 로고
    • Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes
    • Yamada M., Wasserman R., Reichard B. A., Shane S., Caton A. J. and Rovera G. (1991) Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes. J. exp. Med. 173, 395-407.
    • (1991) J. Exp. Med. , vol.173 , pp. 395-407
    • Yamada, M.1    Wasserman, R.2    Reichard, B.A.3    Shane, S.4    Caton, A.J.5    Rovera, G.6
  • 77
    • 0029084986 scopus 로고
    • B cell superantigens: Implications for selection of the human antibody repertoire
    • Zouali M. (1995) B cell superantigens: implications for selection of the human antibody repertoire. Immun. Today 16, 399-405.
    • (1995) Immun. Today , vol.16 , pp. 399-405
    • Zouali, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.