Development of a high-throughput robotic fluorescence-based assay for HsEg5 inhibitor screening

Analytical Biochemistry

Volumn 345, Issue 2, 2005, Pages 326-335

  Zhang, Bin ^a   Senator, David ^a   Wilson, Christopher J ^a   Ng, Shi Chung ^a  

^a ARQULE INC   (United States)

Author keywords

ATPase; Fluorescence; High throughput screening; HsEg5; Inhibitor

Indexed keywords

COLORIMETRY; ROBOTICS;

ATPASE; HIGH THROUGHPUT SCREENING; HSEG5; INHIBITOR; INHIBITOR SCREENINGS; INHIBITORY ACTIVITY; LIMITED DYNAMIC RANGES; SPECIFIC INHIBITORS;

FLUORESCENCE;

ANTINEOPLASTIC AGENT; CK 0106023; CK 1016023; HSEG5 INHIBITOR; ISPINESIB; UNCLASSIFIED DRUG;

ACCURACY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CALCULATION; COLORIMETRY; CONCENTRATION RESPONSE; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVITY; FLUORESCENCE; HYDROLYSIS; IC 50; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; ROBOTICS; SENSITIVITY AND SPECIFICITY;

EID: 25444501831     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2005.07.020     Document Type: Article

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