Murine psoriasis-like disorder induced by naive CD4+ T cells

Nature Medicine

Volumn 3, Issue 2, 1997, Pages 183-188

  Schön, Michael P ^a   Detmar, Michael ^b   Parker, Christina M ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; MOUSE; MOUSE STRAIN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PSORIASIS; SKIN CELL; T LYMPHOCYTE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; HUMANS; IMMUNOLOGIC MEMORY; MICE; MICE, INBRED BALB C; MICE, SCID; PSORIASIS; T-LYMPHOCYTE SUBSETS;

ANIMALIA; MURINAE;

EID: 0031047296     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0297-183     Document Type: Article

References (7)

1. Christophers, E. & Sterry, W. in Dermatology in General Medicine (eds. Fitzpatrick, T.B., Eisen, A.Z., Wolff, K., Freedberg, I.M. & Austen, K.F.) 489-514 (McCraw-Hill, New York, 1993).
2. Barker, J.N.W.N. The immunopathology of psoriasis. Bailliere's Clin. Rheumatol. 8, 429-437 (1994).
3. Christophers, E. The immunopathology of psoriasis. Int. Arch. Allergy Immunol. 110, 199-206 (1996).
4. 389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis. Nature Med. 1, 442-447 (1995).
5. Carroll, J.M., Romero, M.R. & Watt, F.M. Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis. Cell 83, 957-968 (1995).
6. Groves, R.W., Mizutani, H., Kieffer, J.D. & Kupper, T.S. Inflammatory skin disease in transgenic mice that express high levels of interleukin 1α in basal epidermis. Proc. Natl. Acad. Sci. USA 92, 11874-11878 (1995).
7. Wilson, J.B., Weinberg, W., Johnson, R., Yuspa, S. & Levine, A.J. Expression of the BNLF-1 oncogene of Epstein-Barr virus in the skin of transgenic mice induces hyperplasia and aberrant expression of keratin 6. Cell 61, 1315-1327 (1990).