Lysophosphatidic acid inhibits Ca2+ signaling in response to epidermal growth factor receptor stimulation in human astrocytoma cells by a mechanism involving phospholipase Cγ and a G(αi) protein

Journal of Neurochemistry

Volumn 75, Issue 4, 2000, Pages 1575-1582

  Hernández, Marita ^a,b   Barrero, María José ^a,b   Crespo, Mariano Sánchez ^a,b,c   Nieto, María Luisa ^a,b  

^a UNIVERSITY OF VALLADOLID   (Spain)

^b HOSPITAL CLÍNICO UNIVERSITARIO DE VALLADOLID   (Spain)

^c UNIVERSITY OF VALLADOLID   (Spain)

Author keywords

Astrocyte; Growth factors; Lipid mediators; Mitogen activated protein kinase; Phospholipase

Indexed keywords

CALCIUM; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GENE PRODUCT; GUANINE NUCLEOTIDE BINDING PROTEIN; LYSOPHOSPHATIDIC ACID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C; SPHINGOSINE 1 PHOSPHATE;

ARTICLE; ASTROCYTOMA CELL; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

ASTROCYTOMA; CALCIUM SIGNALING; EPIDERMAL GROWTH FACTOR; GROWTH SUBSTANCES; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; ISOENZYMES; LYSOPHOSPHOLIPIDS; MAP KINASE SIGNALING SYSTEM; NUCLEAR PROTEINS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, LYSOPHOSPHATIDIC ACID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; VIRULENCE FACTORS, BORDETELLA;

EID: 0033822092     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0751575.x     Document Type: Article

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