Correction of the neuropathogenic human apolipoprotein E4 (APOE4) gene to APOE3 in vitro using synthetic RNA/DNA oligonucleotides (chimeraplasts)

Journal of Molecular Neuroscience

Volumn 25, Issue 1, 2005, Pages 95-103

  Tagalakis, Aristides D ^a   Dickson, J George ^b   Owen, James S ^a   Simons, J Paul ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Alzheimer's disease; apoE genotypes; Gene repair; Synthetic oligonucleotides

Indexed keywords

APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; DNA; OLIGONUCLEOTIDE; POLYETHYLENEIMINE; RNA; APOLIPOPROTEIN E;

ALLELE; ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CHIMERAPLASTY; CHO CELL; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; GENE SEQUENCE; GENOTYPE; HOMOZYGOSITY; LYMPHOCYTE; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR; WILD TYPE; ANIMAL; CHEMISTRY; CYTOLOGY; GENE THERAPY; GENETICS; HAMSTER; HUMAN; METHODOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

CRICETULUS GRISEUS;

ANIMALS; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; BASE SEQUENCE; CHO CELLS; CRICETINAE; DNA; GENE THERAPY; GENOTYPE; HUMANS; LYMPHOCYTES; MOLECULAR SEQUENCE DATA; NERVOUS SYSTEM DISEASES; OLIGONUCLEOTIDES; RNA;

EID: 25144511563     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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