Insulin modulates PC-1 processing and recruitment in cultured human cells

American Journal of Physiology - Endocrinology and Metabolism

Volumn 284, Issue 3 47-3, 2003, Pages

  Menzaghi, C ^a,c   Di Paola, R ^c   Baj, G ^a,d   Funaro, A ^a,b   Arnulfo, A ^a,d   Ercolino, T ^c   Surico, N ^d   Malavasi, F ^a,b   Trischitta, V ^c,e  

^a UNIVERSITY OF TURIN   (Italy)

^b Experimental Medicine Center   (Italy)

^c CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^d UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Growth factor and ectoenzyme; Insulin desensitization; Insulin receptor; Insulin resistance; Plasma cell glycoprotein 1

Indexed keywords

GLYCOPROTEIN; GLYCOSIDASE; INSULIN; INSULIN RECEPTOR; MONENSIN; PHOSPHATIDYLINOSITOL 3 KINASE; PLASMA CELL GLYCOPROTEIN 1; RAPAMYCIN; S6 KINASE; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; AUTOPHOSPHORYLATION; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; DESENSITIZATION; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

EID: 0037370739     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00503.2001     Document Type: Article

References (34)

1. Beck-Nielsen H and Groop LC. Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus. J Clin Invest 94: 1714-1721, 1994.
2. Belli SI and Goding JW. Biochemical characterization of human PC-1, an enzyme possessing alkaline phosphodiesterase I and nucleotide pyrophosphatase activities. Eur J Biochem 226: 433-443, 1994.
3. Belli SI, Sali A, and Goding JW. Divalent cations stabilize the conformation of plasma cell membrane glycoprotein PC-1 (alkaline phosphodiesterase I). Biochem J 304: 75-80, 1994.
4. Bollen M, Gijsbers R, Ceulemans H, Stalmans W, and Stefan C. Nucleotide pyrophosphatases/phosphodiesterases on the move. Crit Rev Biochem Mol Biol 35: 393-432, 2000.
5. Costanzo BV, Trischitta V, Di Paola R, Spampinato D, Pizzuti A, Vigneri R, and Frittitta L. The Q allele variant (GLN121) of membrane glycoprotein PC-1 interacts with the insulin receptor and inhibits insulin signaling more effectively than the common K allele variant (LYS121). Diabetes 50: 831-836, 2001.
6. Frittitta L, Ercolino T, Bozzali M, Argiolas A, Graci S, Santagati MG, Spampinato D, Di Paola R, Cisternino C, Tassi V, Vigneri R, Pizzuti A, and Trischitta V. A cluster of three single nucleotide polymorphisms in the 3′-untranslated region of human glycoprotein PC-1 gene stabilizes PC-1 mRNA and is associated with increased PC-1 protein content and insulin resistance-related abnormalities. Diabetes 50: 1952-1955, 2001.
7. Frittitta L, Sbraccia P, Costanzo BV, Tassi V, D'Adamo M, Spampinato D, Ercolino T, Purrello F, Tamburrano G, Vigneri R, and Trischitta V. High insulin levels do not influence PC-1 gene expression and protein content in human muscle tissue and hepatoma cells. Diabetes Metab Res Rev 16: 26-32, 2000.
8. Frittitta L, Spampinato D, Solini A, Nosadini R, Goldfine ID, Vigneri R, and Trischitta V. Elevated PC-1 content in cultured skin fibroblasts correlates with decreased in vivo and in vitro insulin action in nondiabetic subjects: evidence that PC-1 may be an intrinsic factor in impaired insulin receptor signaling. Diabetes 47: 1095-1100, 1998.
9. Frittitta L, Youngren J, Vigneri R, Maddux BA, Trischitta V, and Goldfine ID. PC-1 content in skeletal muscle of non-obese, non-diabetic subjects: relationship to insulin receptor tyrosine kinase and whole body insulin sensitivity. Diabetologia 39: 1190-1195, 1996.
10. Frittitta L, Youngren JF, Sbraccia P, D'Adamo M, Buongiorno A, Vigneri R, Goldfine ID, and Trischitta V. Increased adipose tissue PC-1 protein content, but not tumour necrosis factor-alpha gene expression, is associated with a reduction of both whole body insulin sensitivity and insulin receptor tyrosine-kinase activity. Diabetologia 40: 282-289, 1997.
11. Funaro A, De Monte LB, Dianzani U, Forni M, and Malavasi F. Human CD38 is associated to distinct molecules which mediate transmembrane signaling in different lineages. Eur J Immunol 23: 2407-2411, 1993.
12. Goding JW and Howard MC. Ecto-enzymes of lymphoid cells. Immunol Rev 161: 5-10, 1998.
13. Goding JW, Terkeltaub R, Maurice M, Deterre P, Sali A, and Belli SI. Ecto-phosphodiesterase/pyrophosphatase of lymphocytes and non-lymphoid cells: structure and function of the PC-1 family. Immunol Rev 161: 11-26, 1998.
14. Jackson JG, White FM, and Yee D. Insulin receptor substrate-1 is the predominant signaling molecule activated by insulin-like growth factor, insulin, and interleukin-4 in estrogen receptor positive human breast cancer cells. J Biol Chem 273: 9994-10003, 2001.
15. Kahn BB and Flier JS. Obesity and insulin resistance. J Clin Invest 106: 473-481, 2000.
16. Maddux BA and Goldfine ID. Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor alpha-subunit. Diabetes 49: 13-19, 2000.
17. Maddux BA, Sbraccia P, Kumakura S, Sasson S, Youngren J, Fisher A, Spencer S, Grupe A, Henzel W, Stewart TA, Reaven GM, and Golfine ID. Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus. Nature 373: 448-451, 1995.
18. Pitterle DM, Sperling RT, Myers MG, White MF, and Blackshear PJ. Early biochemical events in insulin-stimulated fluid phase endocytosis. Am J Physiol Endocrinol Metab 276: E94-E105, 1999.
19. Pizzuti A, Frittitta L, Argiolas A, Baratta R, Goldfine ID, Bozzali M, Ercolino T, Scarlato G, Iacoviello L, Vigneri R, Tassi V, and Trischitta V. A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance. Diabetes 48: 1881-1884, 1999.
20. Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 37: 1595-1607, 1988.
21. Sakoda H, Ogihara T, Anai M, Funaki M, Inukai K, Katagiri H, Fukushima Y, Onishi Y, Ono H, Yazaki Y, Kikuchi M, Oka Y, and Asano T. No correlation of plasma cell 1 overexpression with insulin resistance in diabetic rats and 3T3-L1 adipocytes. Diabetes 48: 1365-1371, 1999.
22. Sarvazyan NA, Lim WK, and Neubig RR. Fluorescence analysis of receptor-G protein interaction in cell membranes. Biochemistry 41: 12858-12867, 2002.
23. i1α and βγ binding. SPIE 3256: 122-131, 1998.
24. Shao J, Catalano PM, Yamashita H, Ruyter I, Smith S, Youngren J, and Friedman JE. Decreased insulin receptor tyrosine kinase activity and plasma cell membrane glycoprotein-1 overexpression in skeletal muscle from obese women with gestational diabetes mellitus (GDM): evidence for increased serine/threonine phosphorylation in pregnancy and GDM. Diabetes 49: 603-610, 2000.
25. Solan JL, Deftos LJ, Goding JW, and Terkeltaub RA. Expression of the nucleoside triphosphate pyrophosphohydrolase PC-1 is induced by basic fibroblast growth factor (bFGF) and modulated by activation of the protein kinase A and C pathways in osteoblast-like osteosarcoma cells. J Bone Miner Res 11: 183-192, 1994.
26. Somwart R, Niu W, Kim DY, Sweeney G, Randhawa VK, Huang C, Ramlal T, and Klip A. Differential effects of phosphatidylinositol 3-kinase inhibition on intracellular signals regulating GLUT4 translocation and glucose transport. J Biol Chem 276: 46079-46087, 2001.
27. Teno S, Kanno H, Oga S, Kumakura S, Kanamuro R, and Iwamoto Y. Increased activity of membrane glycoprotein PC-1 in the fibroblasts from non-insulin-dependent diabetes mellitus patients with insulin resistance. Diabetes Res Clin Pract 45: 25-30, 1999.
28. Tomazic M, Janez A, Sketelj A, Kocijancic A, Eckel J, and Sharma PM. Comparison of alterations in insulin signalling pathway in adipocytes from Type II diabetic pregnant women and women with gestational diabetes mellitus. Diabetologia 45: 502-508, 2002.
29. Virkamaki A, Ueki K, and Kahn CR. Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance. J Clin Invest 103: 931-943, 1999.
30. Whitehead JP, Humphreys PJ, Dib K, Goding JW, and O'Rahilly S. Expression of the putative inhibitor of the insulin receptor tyrosine kinase PC-1 in dermal fibroblasts from patients with syndromes of severe insulin resistance. Clin Endocrinol (Oxf) 47: 65-70, 1997.
31. Yang J, Clarke JF, Ester CJ, Young PW, Kasuga M, and Molman GD. Phosphatidylinositol 3-kinase acts at an intracellular membrane site to enhance GLUT4 exocytosis in 3T3-L1 cells. Biochem J 313: 125-131, 1996.
32. Youngren JF, Maddux BA, Sasson S, Sbraccia P, Tapscott EB, Swanson MS, Dohm GL, and Goldfine ID. Skeletal muscle content of membrane glycoprotein PC-1 in obesity. Relationship to muscle glucose transport. Diabetes 45: 1324-1328, 1996.
33. Zimmermann H. Two novel families of ectonucleotidases: molecular structures, catalytic properties and a search for function. Trends Pharmacol Sci 20: 231-236, 1999.
34. Zubiaur M, Fernandez O, Ferrero E, Salmeròn J, Malissen B, Malavasi F, and Sancho J. CD38 is associated with lipid rafts and upon receptor stimulation leads to Akt/PKB and Erk activation in the absence of the CD3-ζ immune receptor tyrosinebased activation motifs. J Biol Chem 277: 13-22, 2002.