The nucleoside triphosphate pyrophosphohydrolase isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles

Journal of Rheumatology

Volumn 28, Issue 12, 2001, Pages 2681-2691

  Johnson, K ^a   Pritzker, K ^a   Goding, J ^a   Terkeltaub, R ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Autotaxin PD I ; B10 PDNP3; Chondrocalcinosis; Osteoarthritis; Pyrophosphate

Indexed keywords

ADENOSINE TRIPHOSPHATE; AUTOTAXIN; CALCIUM; INORGANIC PYROPHOSPHATASE; ISOENZYME; LIPOCORTIN 5; NUCLEOSIDE DERIVATIVE; PHOSPHATE; PROTEIN ANTIBODY; PROTEIN PC 1; PROTEIN PDNP3; UNCLASSIFIED DRUG;

AGING; APOPTOSIS; ARTICLE; CALCIFICATION; CARTILAGE CELL; CHONDROCALCINOSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; GENE EXPRESSION REGULATION; GENE TRANSFER; HUMAN; HUMAN CELL; MINERALIZATION; OSTEOARTHRITIS; PRECIPITATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; AUTOCRINE MOTILITY FACTOR; CARTILAGE, ARTICULAR; CASPASE 1; CELLS, CULTURED; CHONDROCALCINOSIS; CHONDROCYTES; EXTRACELLULAR MATRIX; GLYCOPROTEINS; HUMANS; IN SITU NICK-END LABELING; ISOENZYMES; KNEE JOINT; MEMBRANE GLYCOPROTEINS; MULTIENZYME COMPLEXES; PHOSPHODIESTERASE I; PHOSPHORIC DIESTER HYDROLASES; PYROPHOSPHATASES; RECOMBINANT PROTEINS; TRANSFECTION; UP-REGULATION;

EID: 0035199295     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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