In vitro allergy diagnosis: Should we follow the flow?

Clinical and Experimental Allergy

Volumn 34, Issue 3, 2004, Pages 332-339

  Ebo, D G ^a   Hagendorens, M M ^a   Bridts, C H ^a   Schuerwegh, A J ^a   De Clerck, L S ^a   Stevens, W J ^a,b  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b Laboratorium Immunologie   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; AUTOANTIBODY; BETA LACTAM ANTIBIOTIC; BIOLOGICAL MARKER; CD63 ANTIGEN; DIPYRONE; IMMUNOGLOBULIN E; LATEX; MUSCLE RELAXANT AGENT; RUBBER; VENOM;

ALLERGY; BASOPHIL; CELL ACTIVATION; CHRONIC URTICARIA; DRUG HYPERSENSITIVITY; FLOW CYTOMETRY; FOOD; HOUSE DUST; HUMAN; HYMENOPTERA; IMMUNOSTIMULATION; IN VITRO STUDY; MITE; POLLEN; PRACTICE GUIDELINE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVIEW;

ALLERGENS; ANTIGENS, CD; BASOPHILS; BIOLOGICAL MARKERS; FLOW CYTOMETRY; HISTAMINE RELEASE; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; LEUKOCYTE COUNT; PHOSPHORIC DIESTER HYDROLASES; PLATELET MEMBRANE GLYCOPROTEINS; PYROPHOSPHATASES;

EID: 1642395034     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2004.01891.x     Document Type: Review

References (98)

1. Young E, Stoneham MD, Petruckevitch A, Barton J, Rona R. A population study of food intolerance. Lancet 1994; 343:1127-30.
2. Ortolani C, Ispano M, Pastorello EA, Ansaloni R, Magri GC. Comparison of results of skin prick tests (with fresh foods and commercial food extracts) and RAST in 100 patients with oral allergy syndrome. J Allergy Clin Immunol 1989; 83:683-90.
3. Asero R, Mistrello G, Roncarolo D, Antoniotti P, Cislaghi C, Falagiani P. A new apple extract. Allergy 1999; 54:87-8.
4. Lockey RF. Adverse reactions associated with skin testing and immunotherapy. Allergy Proc 1995; 16:293-6.
5. Hamilton RG, Adkinson Jr NF. Diagnosis of natural rubber latex allergy: multicenter latex skin testing efficacy study Multicenter Latex Skin Testing Study Task Force. J Allergy Clin Immunol 1998; 102:482-90.
6. Ruëff F, Przybilla B, Müller U, Mosbech H. The sting challenge test in Hymenoptera venom allergy. Position paper of the Subcommittee on Insect Venom Allergy of the European Academy of Allergology and Clinical Immunology. Allergy 1996; 51:216-25.
7. Pajno GB, Passalacqua G, Magazzu G, Barberio G, Vita D, Canonica GW. Anaphylaxis to sesame. Allergy 2000; 55:199-201.
8. Skamstrup HK, Vestergaard H, Stahl SP et al. Double-blind, placebo-controlled food challenge with apple. Allergy 2001; 56:109-17.
9. Hamilton RG. Clinical laboratory assessment of IgE-dependent hypersensitivity. J Allergy Clin Immunol 2003: S687-701.
10. Mari A, lacovacci P, Afferni C et al. Specific IgE to cross-reactive carbohydrate determinants strongly affect the in vitro diagnosis of allergic diseases. J Allergy Clin Immunol 1999; 103:1005-11.
11. Aalberse RC, Akkerdaas J, van Ree R. Cross-reactivity of IgE antibodies to allergens. Allergy 2001; 56:478-90.
12. van Ree R. Carbohydrate epitopes and their relevance for the diagnosis and treatment of allergic diseases. Int Arch Allergy Immunol 2002; 129:189-97.
13. Bircher AJ, Van Melle G, Haller E, Curty B, Frei PC. IgE to food allergens are highly prevalent in patients allergic to pollens, with and without symptoms of food allergy. Clin Exp Allergy 1994; 24:367-74.
14. Schafer T, Przybilla B. IgE antibodies to Hymenoptera venoms in the serum are common in the general population and are related to indications of atopy. Allergy 1996; 51:372-7.
15. Ebo DG, Stevens WJ, Bridts CH, De Clerck LS. Latex-specific IgE, skin testing, and lymphocyte transformation to latex in latex allergy. J Allergy Clin Immunol 1997; 100:618-23.
16. Stevens WJ, Ebo DG, De Clerck LS, Bridts CH, De Gendt CM, Mertens AV. Evolution of lymphocyte transformation to wasp venom antigen during immunotherapy for wasp venom anaphylaxis. Clin Exp Allergy 1998; 28:249-52.
17. Nolte H. The clinical utility of basophil histamine release. Allergy Proc 1993; 14:251-4.
18. DeWeek AL, Stadler BM, Urwyler A, Wehner HU, Bühlmann RP. Cellular allergen stimulation test (CAST). Allergy Clin Immunol News 1993; 5:9-14.
19. Sanz ML, Prieto I, Oehling A. The histamine release test as an important complement to the diagnosis of allergic diseases. Allergy Clin Immunol News 1995; 7:56-60.
20. De Weck AL. Zellulärer Allergen Stimulieringstest (CAST). Eine Übersicht und kritische Auswertung der klinischen Anwendung in der Allergiediagnose. Allergologie 1997; 20:487-502.
21. Crockard AD, Ennis M. Basophil histamine release tests in the diagnosis of allergy and asthma. Clin Exp Allergy 2001; 31:345-50.
22. Demoly P, Lebel B, Arnoux B. Allergen-induced mediator release tests. Allergy 2003; 58:553-8.
23. Moneret-Vautrin DA, Sainte-Laudy J, Kanny G, Fremont S. Human basophil activation measured by CD63 expression and LTC4 release in IgE-mediated food allergy. Ann Allergy Asthma Immunol 1999; 82:33-40.
24. Bochner BS, Sterbinsky SA, Saini SA, Columbo M, Macglashan DW. Studies of cell adhesion and flow cytometric analyses of degranulation, surface phenotype, and viability using human eosinophils, basophils, and mast cells. Methods 1997; 13:61-8.
25. Bochner BS. Systemic activation of basophils and eosinophils: markers and consequences. J Allergy Clin Immunol 2000; 106:S292-302.
26. Nieuwenhuis HK, vanOosterhout JJ, Rozemuller E, van Iwaarden F, Sixma JJ. Studies with a monoclonal antibody against activated platelets: evidence that a secreted 53,000-molecular weight lysosome-like granule protein is exposed on the surface of activated platelets in the circulation. Blood 1987; 70:838-45.
27. Metzelaar MJ, Wijngaard PL, Peters PJ, Sixma JJ, Nieuwenhuis HK, Clevers HC. CD63 antigen. A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells. J Biol Chem 1991; 266:3239-45.
28. Füreder W, Agis H, Sperr WR, Lechner K, Valent P. The surface membrane antigen phenotype of human blood basophils. Allergy 1994; 49:861-5.
29. Valent P, Schernthaner GH, Sperr WR et al. Variable expression of activation-linked surface antigens on human mast cells in health and disease. Immunol Rev 2001; 179:74-81.
30. Yoshimura C, Yamaguchi M, Iikura M et al. Activation markers of human basophils: CD69 expression is strongly and preferentially induced by IL-3. J Allergy Clin Immunol 2002; 109:817-23.
31. Hauswirth AW, Natter S, Ghannadan M et al. Recombinant allergens promote expression of CD203c on basophils in sensitized individuals. J Allergy Clin Immunol 2002; 110:102-9.
32. Sainte-Laudy J, Sabbah A, Vallon C, Guerin JC. Analysis of anti-IgE and allergen induced human basophil activation by flow cytometry. Comparison with histamine release. Inflamm Res 1998; 47:401-8.
33. Lambert C, Guilloux L, Dzviga C, Gourgaud-Massias C, Genin C. Flow cytometry versus histamine release analysis of in vitro basophil degranulation in allergy to Hymenoptera venom. Cytometry 2003; 52B:13-9.
34. Deissler H, Lottspeich F, Rajewsky MF. Affinity purification and cDNA cloning of rat neural differentiation and tumor cell surface antigen gp13ORB13-6 reveals relationship to human and murine PC-1. J Biol Chem 1995; 270:9849-55.
35. Deissler H, Blass-Kampmann S, Bruyneel E, Marcel M, Rajewsky MF. Neural cell surface differentiation antigen gp130(RB13-6) induces fibroblasts and glioma cells to express astroglial proteins and invasive properties. FASEB J 1999; 13:657-66.
36. Buhring HJ, Seiffert M, Giesert C et al. The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/ phosphodiesterase 3. Blood 2001; 97:3303-5.
37. Buckley MF, Loveland KA, McKinstry WJ, Garson OM, Goding JW. Plasma cell membrane glycoprotein PC-1. cDNA cloning of the human molecule, amino acid sequence, and chromosomal location. J Biol Chem 1990; 265:17506-11.
38. Murata J, Lee HY, Clair T et al. cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases. J Biol Chem 1994; 269:30479-84.
39. Buhring HJ, Simmons PJ, Pudney M et al. The monoclonal antibody 97A6 defines a novel surface antigen expressed on human basophils and their multipotent and unipotent progenitors. Blood 1999; 94:2343-56.
40. Kurimoto Y, De Week AL, Dahinden CA. The effect of interleukin 3 upon IgE-dependent and IgE-independent basophil degranulation and leukotriene generation. Eur J Immunol 1991; 21: 361-8.
41. Sugiyama H, Eda R, Hopp RJ, Bewtra AK, Townley RG. Importance of interleukin-3 on histamine release from human basophils. Ann Allergy 1993; 71:391-5.
42. Miadonna A, Salmaso C, Cottini M, Milazzo N, Tedeschi A. Enhancement of basophil histamine release by interleukin-3: reduced effect in atopic subjects. Allergy 1996; 51:525-31.
43. Cozon G, Ferrandiz J, Peyramond D, Brunet J. Detection of activated basophils using flow cytometry for diagnosis in atopic patients. Allergol Immunopathol (Madr) 1999; 27:182-7.
44. Binder M, Fierlbeck G, King T, Valent P, Buhring HJ. Individual hymenoptera venom compounds induce upregulation of the basophil activation marker ectonucleotide pyrophosphatase/phosphodiesterase 3 (CD203c) in sensitized patients. Int Arch Allergy Immunol 2002; 129:160-8.
45. Lie WJ, Mul FP, Roos D, Verhoeven AJ, Knol EF. Degranulation of human basophils by picomolar concentrations of IL-3, IL-5, or granulocyte-macrophage colony-stimulating factor. J Allergy Clin Immunol 1998; 101:683-90.
46. Lie WJ, Van der Veen MJ, Knol EF et al. Influence of bronchial allergen challenge on histamine release by human basophils. Clin Exp Allergy 2000; 30:882-90.
47. Abrahamsen O, Haas H, Schreiber J, Schlaak M. Differential mediator release from basophils of allergic and non-allergic asthmatic patients after stimulation with anti-IgE and C5a. Clin Exp Allergy 2001:368-78.
48. Kleine Budde I, de Heer PG, van der Zee JS. The stripped basophil histamine release bioassay as a tool for the detection of allergen-specific IgE in serum. Int Arch Allergy Immunol 2001; 126:277-85.
49. Ebo DG, Lechkar B, Schuerwegh AJ, Bridts CH, De Clerck LS, Stevens WJ. Validation of a two-color flow cytometric assay detecting in vitro basophil activation for the diagnosis of IgE-mediated natural rubber latex allergy. Allergy 2002; 57:706-12.
50. Sanz ML, Gamboa PM, Antepara I et al. Flow cytometric basophil activation test by detection of CD63 expression in patients with immediate-type reactions to betalactam antibiotics. Clin Exp Allergy 2002; 32:277-86.
51. Platz I, Binder M, Marxer A, Lischka G, Valent P, Buhring HJ. Hymenoptera venom-induced upregulation of the basophil activation marker ecto-nucleotide pyrophosphatase/phosphodieserase 3 (E-NNP3, CD203c) in sensitized individuals. Int Arch Allergy Immunol 2001; 126:335-42.
52. Ebo DG, Schuerwegh A, Stevens WJ. Anaphylaxis to starch. Allergy 2000; 55:1098-9.
53. Wedi B, Novacovic V, Koerner M, Kapp A. Chronic urticaria serum induces histamine release, leukotriene production, and basophil CD63 surface expression-inhibitory effects of anti-inflammatory drugs. J Allergy Clin Immunol 2000; 105:552-60.
54. Sanz ML, Maselli JP, Gamboa PM, Oehling A, Dieguez I, De Weck AL. Flow cytometric basophil activation test: a review. J Invest Allergol Clin Immunol 2002; 12:143-54.
55. DeWeck AL, Sanz ML. Flow cytometric cellular allergen stimulation test (FAST/Flow-CAST). Technical and clinical evaluation of a new diagnostic test in allergy and pseudo-allergy. Allergy Clin Immunol Int 2002; 14:204-15.
56. Kazemi-Shirazi L, Niederberger V, Linhart B, Lidholm J, Kraft D, Valenta R. Recombinant marker allergens: diagnostic gatekeepers for treatment of allergy. Int Arch Allergy Immunol 2002; 127:259-68.
57. Chapman DD, Smith AM, Vailes LD, Arruda LK. Recombinant mite allergens: new technologies for the management of patients with asthma. Allergy 1997; 52:374-9.
58. Thomas WR, Smith W. Towards defining the full spectrum of house dust mite allergens. Clin Exp Allergy 1999; 29:1583-7.
59. Sussman GL, Beezhold DH, Kurup VP. Allergens and natural rubber proteins. J Allergy Clin Immunol 2002; 110:S33-9.
60. Müller UR. Recombinant Hymenoptera venom allergens. Allergy 2002; 57:570-6.
61. Kurup VP. Fungal allergens. Curr Allergy Asthma Rep 2003; 3:416-23.
62. Lorenz AR, Schuerer S, Haustein D, Vieths S. Recombinant food allergens. J Chromatogr B Biomed Sci Appl 2001; 756:255-79.
63. Andersson K, Lidholm J. Characteristics and immunobiology of grass pollen allergens. Int Arch Allergy Immunol 2003; 130:87-107.
64. Valenta R, Lidholm J, Niederberger V, Hayek B, Kraft D, Grönland H. The recombinant allergen-based concept of component-resolved diagnostics and immunotherapy (CRD and CRIT). Curr Allergy Asthma Rep 1999; 29:896-904.
65. Pauli G. Evolution in the understanding of cross-reactivities of respiratory allergies: the role of recombinant allergens. Int Arch Allergy Immunol 2000; 123:183-95.
66. Gregoire C, Chapman MD. Recombinant allergens. Clin Rev Allergy Immunol 2001; 21:215-27.
67. Vieths S, Schuerer S, Reindl J et al. Optimized allergen extracts and recombinant allergens in diagnostic application. Allergy 2001; 56:S78-82.
68. Moneret-Vautrin DA, Kanny G, Fremont S. Laboratory tests for diagnosis of food allergy: advantages, disadvantages and future directives. Allerg Immunol (Paris) 2003; 35:113-9.
69. Harwanegg C, Laffer S, Hiller R et al. Microarrayed recombinant allergens for diagnosis of allergy. Clin Exp Allergy 2003; 33:7-13.
70. Sanz ML, Gamboa PM, Garcia-Aviles C et al. Flow-cytometric cellular allergen stimulation test in latex allergy. Int Arch Allergy Immunol 2003; 130:33-9.
71. Paris-Kohler A, Demoly P, Persi L, Lebel B, Bousquet J, Arnoux B. In vitro diagnosis of cypress pollen allergy by using cytofluorimetric analysis of basophils (Basotest). J Allergy Clin Immunol 2000; 105:339-45.
72. Erdmann SM, Heussen N, Moll-Slodowy S, Merk HF, Sachs B. CD63 expression on basophils as a tool for the diagnosis of pollen-associated food allergy: sensitivity and specificity. Clin Exp Allergy 2003; 33:607-14.
73. Ebo DG, Toelen C, Van Tongelen S et al. Validation of a basophil activation test (BAT) for the diagnosis of birch pollen associated apple-mediated oral allergy syndrome (OAS). J Allergy Clin Immunol 2003; 111:S254-5.
74. Abuaf N, Rajoely B, Ghazouani E et al. Validation of a flow cytometric assay detecting in vitro basophil activation for the diagnosis of muscle relaxant allergy. J Allergy Clin Immunol 1999; 104:411-8.
75. Kahlert H, Cromwell O, Fiebig H. Measurement of basophil-activating capacity of grass pollen allergens, allergoids and hypoallergenic recombinant derivates by flow cytometry using anti-CD203c. Clin Exp Allergy 2003; 33:1266-72.
76. Sihra BS, Kon OM, Grant JA, Kay AB. Expression of high-affinity receptors (FceRI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: relationship to total serum IgE levels. J Allergy Clin Immunol 1997; 99:699-706.
77. Boumiza R, Monneret G, Forissier MF et al. Marked improvement of the basophil activation test by detecting CD203c instead of CD63. Clin Exp Allergy 2003; 33:259-65.
78. Ebo DG, Lechkar B, Schuerwegh AJ, Bridts CH, De Clerck LS, Stevens WJ. Comments regarding 'Marked improvement of the basophil activation test by detecting CD203c in stead of CD63' by Boumiza et al. [Correspondence]. Clin Exp Allergy 2003; 33:849.
79. De Week AL, Sanz ML. For allergy diagnostic flow cytometry, detection of CD203c in stead of CD63 is not at all an improvement in other hands [Correspondence]. Clin Exp Allergy 2003; 33:849-52.
80. Sperr WR, Agis H, Semper H et al. Inhibition of allergen-induced histamine release from human basophils by cyclosporine A and FK-506. Int Arch Allergy Immunol 1997; 114:68-73.
81. Majlesi Y, Samorapoompichit P, Hauswirth AW et al. Cerivastatin and atorvastatin inhibit IL-3-dependent differentiation and IgE-mediated histamine release in human basophils and downmodulate expression of the basophil-activation antigen CD203c/E-NPP3. J Leukoc Biol 2003; 73:107-17.
82. Fortson JS, Zone JJ, Hammond ME, Groggel GC. Hypocomplementemic urticarial vasculitis syndrome responsive to dapsone. J Am Acad Dermatol 1986; 15:1137-42.
83. Nurnberg W, Grabbe J, Czarnetzki BM. Urticarial vasculitis syndrome effectively treated with dapsone and pentoxifylline. Acta Derm Venereol 1995; 75:54-6.
84. Decco ML, Neeno TA, Hunt LW, O'Connell EJ, Yunginger JW, Sachs MI. Nebulized lidocaine in the treatment of severe asthma in children: a pilot study. Ann Allergy Asthma Immunol 1999; 82:29-32.
85. Ghannadan M, Hauswirth AW, Schernthaner GH et al. Detection of novel CD antigens on the surface of human mast cells and basophils. Int Arch Allergy Immunol 2002; 127:299-307.
86. Sanz ML, Sanchez G, Gamboa PM et al. Allergen-induced basophil activation: CD63 cell expression detected by flow cytometry in patients allergic to Dermatophagoides pteronyssinus and Lolium perenne. Clin Exp Allergy 2001; 31:1007-13.
87. Saporta M, Kamei S, Persi L, Bousquet J, Arnoux B. Basophil activation during pollen season in patients monosensitized to grass pollens. Allergy 2001; 56:442-5.
88. Sainte-Laudy J, Sabbah A, Drouet M, Lauret MG, Loiry M. Diagnosis of venom allergy by flow cytometry. Correlation with clinical history, skin tests, specific IgE, histamine and leukotriene C4 release. Clin Exp Allergy 2000; 30:1166-71.
89. Gamboa PM, Sanz ML, Caballero MR et al. Use of CD63 expression as a marker of in vitro basophil activation and leukotriene determination in metamizol allergic patients. Allergy 2003; 58:312-7.
90. Schleimer RP, Derse CP, Friedman B et al. Regulation of human basophil mediator release by cytokines. I. Interaction with antiinflammatory steroids. J Immunol 1989; 143:1310-7.
91. Knol EF, Mul FP, Lie WJ, Verhoeven AJ, Roos D. The role of basophils in allergic disease. Eur Respir J 1996; 22 (Suppl.):S126-31.
92. Ebo DG, Piel GC, Conraads V, Stevens WJ. IgE-mediated anaphylaxis after first intravenous infusion of cyclosporine. Ann Allergy Asthma Immunol 2001; 87:243-5.
93. Harle DG, Baldo BA, Fisher MM. Assays for, and cross-reactivities of, IgE antibodies to the muscle relaxants gallamine, decamethonium and succinylcholine (suxamethonium). J Immunol Methods 1985; 78:293-305.
94. Zuberbier T, Henz BM, Fiebiger E, Maurer D, Stingl G. Anti-FcepsilonRIalpha serum autoantibodies in different subtypes of urticaria. Allergy 2000; 55:951-4.
95. Plebani M, Borghesan F, Basso D, Faggian D. Reveiver-operating characteristic (ROC) curves: a fundamental tool for improving the clinical usefulness of in vitro IgE tests. Allergy 1996: 407-11.
96. Greiner M, Pfeiffer D, Smith RD. Principles and practical application of the receiver-operating characteristic analysis for diagnostic tests. Prev Vet Med 2000; 45:23-41.
97. Valenta R, Kraft D. Recombinant allergen molecules: tools to study effector cell activation. Immunol Rev 2001; 179:119-27.
98. Varro R, Chen C-H. A no-wash 3-color basophil degrabulation assay using the CD123+HLA DR-phenotype for basophil classification. Cytometry 2000; 10:S116.