IFN-γ sensitizes MIN6N8 insulinoma cells to TNF-α-induced apoptosis by inhibiting NF-κB-mediated XIAP upregulation

Biochemical and Biophysical Research Communications

Volumn 336, Issue 3, 2005, Pages 847-853

  Hun, Sik Kim ^a   Kim, Sunshin ^a   Lee, Myung Shik ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Apoptosis; Diabetes; IFN ; MIN6N8 cell; NF B; TNF ; XIAP

Indexed keywords

ADENOVIRUS VECTOR; ANTISENSE OLIGONUCLEOTIDE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TUMOR NECROSIS FACTOR ALPHA; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; INSULINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIZATION; TUMOR CELL; UPREGULATION;

ANIMALS; APOPTOSIS; CASPASES; CELL LINE, TUMOR; DRUG SYNERGISM; INSULINOMA; INTERFERON TYPE II; ISLETS OF LANGERHANS; MICE; MICE, INBRED NOD; NF-KAPPA B; PANCREATIC NEOPLASMS; PROTEINS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 25144464087     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.08.183     Document Type: Article

References (35)

1. D. Mauricio, and T. Mandrup-Poulsen Apoptosis and the pathogenesis of IDDM: a question of life and death Diabetes 47 1998 1537 1543
2. D.L. Eizirik, and T. Mandrup-Poulsen A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis Diabetologia 44 2001 2115 2133
3. I.L. Campbell, A. Iscaro, and L.C. Harrison IFN-γ and tumor necrosis factor-α: cytotoxicity to murine islets of Langerhans J. Immunol. 141 1988 2325 2329
4. K. Suk, S. Kim, Y.H. Kim, K.A. Kim, I. Chang, H. Yagita, M. Shong, and M.S. Lee IFN-γ/TNF-α synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic β cell death J. Immunol. 166 2001 4481 4489
5. A.A. Beg, and D. Baltimore An essential role for NF-κB in preventing TNF-α-induced cell death Science 274 1996 782 784
6. C.Y. Wang, M.W. Mayo, and A.S. Baldwin Jr. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB Science 274 1996 784 787
7. D.J. Van Antwerp, S.J. Martin, T. Kafri, D.R. Green, and I.M. Verma Suppression of TNF-α-induced apoptosis by NF-κB Science 274 1996 787 789
8. C.Y. Wang, M.W. Mayo, R.G. Korneluk, D.V. Goeddel, and A.S. Baldwin Jr. NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation Science 281 1998 1680 1683
9. C. Stehlik, R. de Martin, I. Kumabashiri, J.A. Schmid, B.R. Binder, and J. Lipp Nuclear factor (NF)-κB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor α-induced apoptosis J. Exp. Med. 188 1998 211 216
10. Z.L. Chu, T.A. McKinsey, L. Liu, J.J. Gentry, M.H. Malim, and D.W. Ballard Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control Proc. Natl. Acad. Sci. USA 94 1997 10057 10062
11. A. Schneider, A. Martin-Villalba, F. Weih, J. Vogel, T. Wirth, and M. Schwaninger NF-κB is activated and promotes cell death in focal cerebral ischemia Nat. Med. 5 1999 554 559
12. A. Dumont, S.P. Hehner, T.G. Hofmann, M. Ueffing, W. Droge, and M.L. Schmitz Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-κB Oncogene 18 1999 747 757
13. I. Chang, S. Kim, J.Y. Kim, N. Cho, Y.H. Kim, H.S. Kim, M.K. Lee, K.W. Kim, and M.S. Lee Nuclear factor κB protects pancreatic β-cells from tumor necrosis factor-α-mediated apoptosis Diabetes 52 2003 1169 1175
14. H. Heimberg, Y. Heremans, C. Jobin, R. Leemans, A.K. Cardozo, M. Darville, and D.L. Eizirik Inhibition of cytokine-induced NF-κB activation by adenovirus-mediated expression of NF-κB super-repressor prevents β-cell apoptosis Diabetes 50 2001 2219 2224
15. N. Giannoukakis, W.A. Rudert, M. Trucco, and P.D. Robbins Protection of human islets from the effects of interleukin-1β By adenoviral gene transfer of an IκB repressor J. Biol. Chem. 275 2000 36509 36513
16. G. Chen, H.E. Hohmer, R. Gasa, V.V. Tran, and C.B. Newgard Selection of insulinoma cell lines with resistance to interleukin-1β- and γ-interferon-induced cytotoxicity Diabetes 49 2000 562 570
17. X. Han, Y. Sun, S. Scott, and D. Bleich Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islet and β-cells Diabetes 50 2001 1047 1055
18. Q.L. Deveraux, and J.C. Reed IAP family proteins-suppressors of apoptosis Genes Dev. 13 1999 239 252
19. M. Holcik, and R.G. Korneluk XIAP, the guardian angel Nat. Rev. Mol. Cell Biol. 2 2001 550 556
20. P. Liston, N. Roy, K. Tamai, C. Lefebvre, S. Baird, G. Cherton-Horvat, R. Farahani, M. McLean, J.E. Ikeda, A. MacKenzie, and R.G. Korneluk Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes Nature 379 1996 349 353
21. D. Xu, Y. Bureau, D.C. McIntyre, D.W. Nicholson, P. Liston, Y. Zhu, W.G. Fong, S.J. Crocker, R.G. Korneluk, and G.S. Robertson Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus J. Neurosci. 19 1999 5026 5033
22. C.W. Xiao, K. Ash, and B.K. Tsang Nuclear factor-κ B-mediated X-linked inhibitor of apoptosis protein expression prevents rat granulosa cells from tumor necrosis factor α-induced apoptosis Endocrinology 142 2001 557 563
23. D. Petrin, A. Baker, S.G. Coupland, P. Liston, M. Narang, K. Damji, B. Leonard, V.A. Chiodo, A. Timmers, W. Hauswirth, R.G. Korneluk, and C. Tsilfidis Structural and functional protection of photoreceptors from MNU-induced retinal degeneration by the X-linked inhibitor of apoptosis Invest. Ophthalmol. Vis. Sci. 44 2003 2757 2763
24. T. Zou, J.N. Rao, X. Guo, L. Liu, H.M. Zhang, E.D. Strauch, B.L. Bass, and J.Y. Wang NF-κB-mediated IAP expression induces resistance of intestinal epithelial cells to apoptosis after polyamine depletion Am. J. Physiol. Cell Physiol. 286 2004 C1009 C1018
25. H. Lin, C. Chen, and B.D. Chen Resistance of bone marrow-derived macrophages to apoptosis is associated with the expression of X-linked inhibitor of apoptosis protein in primary cultures of bone marrow cells Biochem. J. 353 2001 299 306
26. Z. Liu, C. Sun, E.T. Olejniczak, R.P. Meadows, S.F. Betz, T. Oost, J. Herrmann, J.C. Wu, and S.W. Fesik Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain Nature 40 2000 1004 1008
27. A.M. Verhagen, P.G. Ekert, M. Pakusch, J. Silke, L.M. Connolly, G.E. Reid, R.L. Moritz, R.J. Simpson, and D.L. Vaux Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins Cell 102 2000 43 53
28. L. Yang, T. Mashima, S. Sato, M. Mochizuki, H. Sakamoto, T. Yamori, T. Oh-Hara, and T. Tsuruo Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine-conjugated Smac peptide Cancer Res. 63 2003 831 837
29. H.S. Kim, I. Chang, J.Y. Kim, K.H. Choi, and M.S. Lee Caspase-mediated p65 cleavage promotes TRAIL-induced apoptosis Cancer Res. 65 2005 6111 6119
30. M. Karin, and A. Lin NF-κB at the crossroads of life and death Nat. Immunol. 3 2002 221 227
31. K. Suk, I. Chang, Y.H. Kim, S. Kim, J.Y. Kim, H. Kim, and M.S. Lee Interferon γ (IFNγ) and tumor necrosis factor α synergism in ME-180 cervical cancer cell apoptosis and necrosis: IFNγ inhibits cytoprotective NF-κB through STAT1/IRF-1 pathways J. Biol. Chem. 276 2001 13153 13159
32. K. Suk, Y.H. Kim, I. Chang, J.Y. Kim, Y.H. Choi, K.Y. Lee, and M.S. Lee IFNα sensitizes ME-180 human cervical cancer cells to TNFα-induced apoptosis by inhibiting cytoprotective NF-κB activation FEBS Lett. 495 2001 66 70
33. N.A. McMillan, B.W. Carpick, B. Hollis, W.M. Toone, M. Zamanian-Daryoush, and B.R. Williams Mutational analysis of the double-stranded RNA (dsRNA) binding domain of the dsRNA-activated protein kinase, PKR J. Biol. Chem. 270 1995 2601 2606
34. B.D. Williamson, E.A. Carswell, B.Y. Rubin, J.S. Prendergast, and L.J. Old Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon Proc. Natl. Acad. Sci. USA 80 1983 5397 5401
35. V. Ruggiero, J. Tavernier, W. Fiers, and C. Baglioni Induction of the synthesis of tumor necrosis factor receptors by interferon-γ J. Immunol. 136 1986 2445 2450