-
1
-
-
13444282227
-
Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: Initial experience
-
Kuwaki K, Tseng YL, Dor FJ, et al. Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat Med 2005; 11:29-31. With Yamada et al. [2], reports the first experience of the transplantation of organs from GalT-KO pigs in nonhuman primates.
-
(2005)
Nat Med
, vol.11
, pp. 29-31
-
-
Kuwaki, K.1
Tseng, Y.L.2
Dor, F.J.3
-
2
-
-
13444269248
-
Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue
-
Yamada K, Yazawa K, Shimizu A, et al. Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3- galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue. Nat Med 2005; 11:32-34. With Kuwaki et ak. [1], reports the first experience of the transplantation of organs from GalT-KO pigs in nonhuman primates.
-
(2005)
Nat Med
, vol.11
, pp. 32-34
-
-
Yamada, K.1
Yazawa, K.2
Shimizu, A.3
-
3
-
-
4344688865
-
Thrombotic microangiopathy and graft arteriopathy in pig hearts following transplantation into baboons
-
Houser SL, Kuwaki K, Knosalla C, et al. Thrombotic microangiopathy and graft arteriopathy in pig hearts following transplantation into baboons. Xenotransplantation 2004; 11:416-425. Useful description of the thrombotic microangiopathy that develops when classical AHXR is prevented.
-
(2004)
Xenotransplantation
, vol.11
, pp. 416-425
-
-
Houser, S.L.1
Kuwaki, K.2
Knosalla, C.3
-
4
-
-
10044240662
-
Complete inhibition of acute humoral rejection using regulated expression of membrane-tethered anticoagulants on xenograft endothelium
-
Chen D, Weber M, McVey JH, et al. Complete inhibition of acute humoral rejection using regulated expression of membrane-tethered anticoagulants on xenograft endothelium. Am J Transplant 2004; 4:1958-1963.
-
(2004)
Am J Transplant
, vol.4
, pp. 1958-1963
-
-
Chen, D.1
Weber, M.2
McVey, J.H.3
-
5
-
-
13444269380
-
Improved assessment of graft function by echocardiography in cynomolgus monkey recipients of hDAF-transgenic pig cardiac xenografts
-
Stalder M, Tye T, Lam TT, et al. Improved assessment of graft function by echocardiography in cynomolgus monkey recipients of hDAF-transgenic pig cardiac xenografts. J Heart Lung Transplant 2005; 24:215-221.
-
(2005)
J Heart Lung Transplant
, vol.24
, pp. 215-221
-
-
Stalder, M.1
Tye, T.2
Lam, T.T.3
-
6
-
-
4344651097
-
Failure to deplete anti-Galalpha 1-3Gal antibodies after pig-to-baboon organ xenotransplantation by immunoaffinity columns containing multiple Galalpha1-3Gal oligosaccharides
-
Manez R, Domenech N, Centeno A, et al. Failure to deplete anti-Galalpha 1-3Gal antibodies after pig-to-baboon organ xenotransplantation by immunoaffinity columns containing multiple Galalpha1-3Gal oligosaccharides. Xenotransplantation 2004; 11:408-415.
-
(2004)
Xenotransplantation
, vol.11
, pp. 408-415
-
-
Manez, R.1
Domenech, N.2
Centeno, A.3
-
7
-
-
20044391388
-
Administration of GAS914 in an orthotopic pig-to-baboon heart transplantation model
-
Brandl U, Michel S, Erhardt M, et al. Administration of GAS914 in an orthotopic pig-to-baboon heart transplantation model. Xenotransplantation 2005; 12:134-141.
-
(2005)
Xenotransplantation
, vol.12
, pp. 134-141
-
-
Brandl, U.1
Michel, S.2
Erhardt, M.3
-
8
-
-
4444274059
-
Xenotransplantation of human decay accelerating factor transgenic porcine kidney to non-human primates: 4 Years experience at a Canadian center
-
Garcia B, Sun HT, Yang HJ, et al. Xenotransplantation of human decay accelerating factor transgenic porcine kidney to non-human primates: 4 years experience at a Canadian center. Transplant Proc 2004; 36:1714-1716.
-
(2004)
Transplant Proc
, vol.36
, pp. 1714-1716
-
-
Garcia, B.1
Sun, H.T.2
Yang, H.J.3
-
9
-
-
19944428636
-
The effect of soluble complement receptor type 1 on acute humoral xenograft rejection in hDAF-transgenic pig-to-primate life-supporting kidney xenografts
-
Lam TT, Hausen B, Hook L, et al. The effect of soluble complement receptor type 1 on acute humoral xenograft rejection in hDAF-transgenic pig-to-primate life-supporting kidney xenografts. Xenotransplantation 2005; 12:20-29.
-
(2005)
Xenotransplantation
, vol.12
, pp. 20-29
-
-
Lam, T.T.1
Hausen, B.2
Hook, L.3
-
10
-
-
7044235964
-
Anti-non-Gal porcine endothelial cell antibodies in acute humoral xenograft rejection of hDAF-transgenic porcine hearts in cynomolgus monkeys
-
Lam TT, Paniagua R, Shivaram G, et al. Anti-non-Gal porcine endothelial cell antibodies in acute humoral xenograft rejection of hDAF-transgenic porcine hearts in cynomolgus monkeys. Xenotransplantation 2004; 11:531-535.
-
(2004)
Xenotransplantation
, vol.11
, pp. 531-535
-
-
Lam, T.T.1
Paniagua, R.2
Shivaram, G.3
-
11
-
-
7044272896
-
Hyperacute rejection of hDAF-transgenic pig organ xenografts in cynomolgus monkeys: Influence of pre-existing anti-pig antibodies and prevention by the alpha GAL glycoconjugate GAS914
-
Lam TT, Hausen B, Boeke-Purkis K, et al. Hyperacute rejection of hDAF-transgenic pig organ xenografts in cynomolgus monkeys: influence of pre-existing anti-pig antibodies and prevention by the alpha GAL glycoconjugate GAS914. Xenotransplantation 2004; 11:517-524.
-
(2004)
Xenotransplantation
, vol.11
, pp. 517-524
-
-
Lam, T.T.1
Hausen, B.2
Boeke-Purkis, K.3
-
12
-
-
0028889431
-
Human anti-porcine xenogeneic T-cell response: Evidence for allelic specificity of MLR and for both direct and indirect pathways of recognition
-
Yamada K, Sachs DH, DerSimonian H. Human anti-porcine xenogeneic T-cell response: evidence for allelic specificity of MLR and for both direct and indirect pathways of recognition. J Immunol 1995; 155:5249-5256.
-
(1995)
J Immunol
, vol.155
, pp. 5249-5256
-
-
Yamada, K.1
Sachs, D.H.2
DerSimonian, H.3
-
13
-
-
0028406899
-
Porcine aortic endothelial cells activate human T cells: Direct presentation of MHC antigens and costimulation by ligands for human CD2 and CD28
-
Murray AG, Khodadoust MM, Pober JS, et al. Porcine aortic endothelial cells activate human T cells: direct presentation of MHC antigens and costimulation by ligands for human CD2 and CD28. Immunity 1994; 1:57-63.
-
(1994)
Immunity
, vol.1
, pp. 57-63
-
-
Murray, A.G.1
Khodadoust, M.M.2
Pober, J.S.3
-
14
-
-
0034653832
-
Thymic transplantation in miniature swine, II: Induction of tolerance by transplantation of composite thymokidneys to thymectomized recipients
-
Yamada K, Shimizu A, Utsugi R, et al. Thymic transplantation in miniature swine, II: induction of tolerance by transplantation of composite thymokidneys to thymectomized recipients. J Immunol 2000; 164:3079-3086.
-
(2000)
J Immunol
, vol.164
, pp. 3079-3086
-
-
Yamada, K.1
Shimizu, A.2
Utsugi, R.3
-
15
-
-
0041465732
-
Thymic transplantation in miniature swine, III: Induction of tolerance by transplantation of composite thymokidneys across fully major histocompatibility complex-mismatched barriers
-
Yamada K, Vagefi PA, Utsugi R, et al. Thymic transplantation in miniature swine, III: induction of tolerance by transplantation of composite thymokidneys across fully major histocompatibility complex-mismatched barriers. Transplantation 2003; 76:530-536.
-
(2003)
Transplantation
, vol.76
, pp. 530-536
-
-
Yamada, K.1
Vagefi, P.A.2
Utsugi, R.3
-
16
-
-
0038012548
-
Xenogeneic thymokidney and thymic tissue transplantation in a pig-to-baboon model, I: Evidence for pig-specific T-cell unresponsiveness
-
Barth RN, Yamamoto S, LaMattina JC, et al. Xenogeneic thymokidney and thymic tissue transplantation in a pig-to-baboon model, I: evidence for pig-specific T-cell unresponsiveness. Transplantation 2003; 75:1615-1624.
-
(2003)
Transplantation
, vol.75
, pp. 1615-1624
-
-
Barth, R.N.1
Yamamoto, S.2
LaMattina, J.C.3
-
17
-
-
10644296310
-
Cardiac xenotransplantation: Progress toward the clinic
-
McGregor CG, Teotia SS, Byrne GW, et al. Cardiac xenotransplantation: progress toward the clinic. Transplantation 2004; 78:1569-1575. Reports some of the best results to date in a pig-to-nonhuman primate organ transplantation model.
-
(2004)
Transplantation
, vol.78
, pp. 1569-1575
-
-
McGregor, C.G.1
Teotia, S.S.2
Byrne, G.W.3
-
18
-
-
4344630827
-
Effective antiplatelet therapy does not prolong transgenic pig to baboon cardiac xenograft survival
-
Schirmer JM, Pass DN, Byrne GW, et al. Effective antiplatelet therapy does not prolong transgenic pig to baboon cardiac xenograft survival. Xenotransplantation 2004; 11:436-443. Provides evidence that anti-platelet therapy does not reduce the incidence of thrombotic microangiopathy in pig organ grafts after transplantation into nonhuman primates.
-
(2004)
Xenotransplantation
, vol.11
, pp. 436-443
-
-
Schirmer, J.M.1
Pass, D.N.2
Byrne, G.W.3
-
19
-
-
10744228498
-
Suppression of natural and elicited antibodies in pig-to-baboon heart transplantation using a human anti-human CD154 mAb-based regimen
-
Kuwaki K, Knosalla C, Dor FJ, et al. Suppression of natural and elicited antibodies in pig-to-baboon heart transplantation using a human anti-human CD154 mAb-based regimen. Am J Transplant 2004; 4:363-372.
-
(2004)
Am J Transplant
, vol.4
, pp. 363-372
-
-
Kuwaki, K.1
Knosalla, C.2
Dor, F.J.3
-
20
-
-
14644406764
-
Prevention, detection, and management of early bacterial and fungal infections in a preclinical cardiac xenotransplantation model that achieves prolonged survival
-
Teotia SS, Walker RC, Schirmer JM, et al. Prevention, detection, and management of early bacterial and fungal infections in a preclinical cardiac xenotransplantation model that achieves prolonged survival. Xenotransplantation 2005; 12:127-133.
-
(2005)
Xenotransplantation
, vol.12
, pp. 127-133
-
-
Teotia, S.S.1
Walker, R.C.2
Schirmer, J.M.3
-
21
-
-
10744224843
-
Characterization of a CD46 transgenic pig and protection of transgenic kidneys against hyperacute rejection in non-immunosuppressed baboons
-
Loveland BE, Milland J, Kyriakou P, et al. Characterization of a CD46 transgenic pig and protection of transgenic kidneys against hyperacute rejection in non-immunosuppressed baboons. Xenotransplantation 2004; 11:171-183.
-
(2004)
Xenotransplantation
, vol.11
, pp. 171-183
-
-
Loveland, B.E.1
Milland, J.2
Kyriakou, P.3
-
22
-
-
4644297157
-
Transgenic expression in pig hearts of both human decay-accelerating factor and human membrane cofactor protein does not provide an additional benefit to that of human decay-accelerating factor alone in pig-to-baboon xenotransplantation
-
Manez R, Lopez-Pelaez E, Centeno A, et al. Transgenic expression in pig hearts of both human decay-accelerating factor and human membrane cofactor protein does not provide an additional benefit to that of human decay-accelerating factor alone in pig-to-baboon xenotransplantation. Transplantation 2004; 78:930-933.
-
(2004)
Transplantation
, vol.78
, pp. 930-933
-
-
Manez, R.1
Lopez-Pelaez, E.2
Centeno, A.3
-
23
-
-
2442720110
-
Characterization of human CD55 and CD59 transgenic pigs and kidney xenotransplantation in the pig-to-baboon combination
-
Menoret S, Plat M, Blancho G, et al. Characterization of human CD55 and CD59 transgenic pigs and kidney xenotransplantation in the pig-to-baboon combination. Transplantation 2004; 77:1468-1471.
-
(2004)
Transplantation
, vol.77
, pp. 1468-1471
-
-
Menoret, S.1
Plat, M.2
Blancho, G.3
-
24
-
-
10744231680
-
The study of mitoxantrone as a potential immunosuppressor in transgenic pig renal xenotransplantation in baboons: Comparison with cyclophosphamide
-
Ashton-Chess J, Meurette G, Karam G, et al. The study of mitoxantrone as a potential immunosuppressor in transgenic pig renal xenotransplantation in baboons: comparison with cyclophosphamide. Xenotransplantation 2004; 11:112-122.
-
(2004)
Xenotransplantation
, vol.11
, pp. 112-122
-
-
Ashton-Chess, J.1
Meurette, G.2
Karam, G.3
-
25
-
-
0347367029
-
Production of alpha 1,3-galactosyltransferase-deficient pigs
-
Phelps CJ, Koike C, Vaught TD, et al. Production of alpha 1,3-galactosyltransferase-deficient pigs. Science 2003; 299:411-414.
-
(2003)
Science
, vol.299
, pp. 411-414
-
-
Phelps, C.J.1
Koike, C.2
Vaught, T.D.3
-
26
-
-
2442567900
-
Production of {alpha}-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations
-
Kolber-Simonds D, Lai L, Watt SR, et al. Production of {alpha}-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations. Proc Natl Acad Sci U S A 2004; 101:7335-7340. This paper reports the successful production of α1,3-galactosyltransferase gene knockout pigs through nuclear transfer technology using nuclei from a fibroblast line derived from a highly inbred line of miniature swine.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 7335-7340
-
-
Kolber-Simonds, D.1
Lai, L.2
Watt, S.R.3
-
27
-
-
0037468699
-
Histocompatible miniature swine: An inbred large-animal model
-
Mezrich JD, Haller GW, Arn JS, et al. Histocompatible miniature swine: an inbred large-animal model. Transplantation 2003; 75:904-907.
-
(2003)
Transplantation
, vol.75
, pp. 904-907
-
-
Mezrich, J.D.1
Haller, G.W.2
Arn, J.S.3
-
28
-
-
3142717365
-
Alpha1,3-Galactosyltransferase gene-knockout miniature swine produce natural cytotoxic anti-Gal antibodies
-
Dor FJ, Tseng YL, Cheng J, et al. alpha1,3-Galactosyltransferase gene-knockout miniature swine produce natural cytotoxic anti-Gal antibodies. Transplantation 2004; 78:15-20. Provides evidence that, like GalT-KO mice, GalT-KO pigs make natural anti-Gal antibodies.
-
(2004)
Transplantation
, vol.78
, pp. 15-20
-
-
Dor, F.J.1
Tseng, Y.L.2
Cheng, J.3
-
29
-
-
0037087534
-
Vascularized thymic lobe transplantation in miniature swine, I: Vascularized thymic lobe allografts support thymopoiesis
-
LaMattina JC, Kumagai N, Barth RN, et al. Vascularized thymic lobe transplantation in miniature swine, I: vascularized thymic lobe allografts support thymopoiesis. Transplantation 2002; 73:826-831.
-
(2002)
Transplantation
, vol.73
, pp. 826-831
-
-
LaMattina, J.C.1
Kumagai, N.2
Barth, R.N.3
-
30
-
-
1642350860
-
Vascularized thymic lobe transplantation in miniature swine: Thymopoiesis and tolerance induction across fully MHC-mismatched barriers
-
Kamano C, Vagefi PA, Kumagai N, et al. Vascularized thymic lobe transplantation in miniature swine: thymopoiesis and tolerance induction across fully MHC-mismatched barriers. Proc Natl Acad Sci U S A 2004; 101:3827-3832. This study demonstrates that porcine vascularized thymic lobe transplantation induces transplantation tolerance across full MHC-mismatched barriers.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3827-3832
-
-
Kamano, C.1
Vagefi, P.A.2
Kumagai, N.3
-
31
-
-
0033572777
-
Thymic transplantation in miniature swine. I. Development and function of the 'thymokidney.'
-
Yamada K, Shimizu A, Ierino FL, et al. Thymic transplantation in miniature swine. I. Development and function of the 'thymokidney.' Transplantation 1999; 68:1684-1692.
-
(1999)
Transplantation
, vol.68
, pp. 1684-1692
-
-
Yamada, K.1
Shimizu, A.2
Ierino, F.L.3
-
32
-
-
2942661758
-
Acute vascular rejection of xenografts: Roles of natural and elicited xenoreactive antibodies in activation of vascular endothelial cells and induction of procoagulant activity
-
Gollackner B, Goh SK, Qawi I, et al. Acute vascular rejection of xenografts: roles of natural and elicited xenoreactive antibodies in activation of vascular endothelial cells and induction of procoagulant activity. Transplantation 2004; 77:1735-1741.
-
(2004)
Transplantation
, vol.77
, pp. 1735-1741
-
-
Gollackner, B.1
Goh, S.K.2
Qawi, I.3
-
33
-
-
0742305872
-
Absence of humoral and cellular alloreactivity in baboons sensitized to pig antigens
-
Baertschiger RM, Dor FJ, Prabharasuth D, et al. Absence of humoral and cellular alloreactivity in baboons sensitized to pig antigens. Xenotransplantation 2004; 11:27-32. This study demonstrates that sensitization to pig antigens following xenotransplantation will not be detrimental to subsequent allotransplantation.
-
(2004)
Xenotransplantation
, vol.11
, pp. 27-32
-
-
Baertschiger, R.M.1
Dor, F.J.2
Prabharasuth, D.3
-
34
-
-
4344627573
-
Does exposure to swine leukocyte antigens after pig-to-nonhuman primate xenotransplantation provoke antibodies that cross-react with human leukocyte antigens?
-
Key T, Schuurman HJ, Taylor CJ. Does exposure to swine leukocyte antigens after pig-to-nonhuman primate xenotransplantation provoke antibodies that cross-react with human leukocyte antigens? Xenotransplantation 2004; 11:452-456.
-
(2004)
Xenotransplantation
, vol.11
, pp. 452-456
-
-
Key, T.1
Schuurman, H.J.2
Taylor, C.J.3
-
35
-
-
7044284602
-
Reduction of consumptive coagulopathy using porcine cytomegalovirus-free cardiac porcine grafts in pig-to-primate xenotransplantation
-
Mueller NJ, Kuwaki K, Dor FJ, et al. Reduction of consumptive coagulopathy using porcine cytomegalovirus-free cardiac porcine grafts in pig-to-primate xenotransplantation. Transplantation 2004; 78:1449-1453. Provides data on the role of porcine cytomegalovirus in the development of a consumptive coagulopathy after pig organ xenotransplantation.
-
(2004)
Transplantation
, vol.78
, pp. 1449-1453
-
-
Mueller, N.J.1
Kuwaki, K.2
Dor, F.J.3
-
36
-
-
19944426952
-
Early weaning of piglets fails to exclude porcine lymphotropic herpesvirus
-
Mueller NJ, Kuwaki K, Knosalla C, et al. Early weaning of piglets fails to exclude porcine lymphotropic herpesvirus. Xenotransplantation 2005; 12:59-62.
-
(2005)
Xenotransplantation
, vol.12
, pp. 59-62
-
-
Mueller, N.J.1
Kuwaki, K.2
Knosalla, C.3
-
37
-
-
2442455370
-
Activation of porcine cytomegalovirus, but not porcine lymphotropic herpesvirus, in pig-to-baboon xenotransplantation
-
Mueller NJ, Livingston C, Knosalla C, et al. Activation of porcine cytomegalovirus, but not porcine lymphotropic herpesvirus, in pig-to-baboon xenotransplantation. J Infect Dis 2004; 189:1628-1633.
-
(2004)
J Infect Dis
, vol.189
, pp. 1628-1633
-
-
Mueller, N.J.1
Livingston, C.2
Knosalla, C.3
-
38
-
-
3042611661
-
Inhibition of porcine endogenous retroviruses by RNA interference: Increasing the safety of xenotransplantation
-
Karlas A, Kurth R, Denner J. Inhibition of porcine endogenous retroviruses by RNA interference: increasing the safety of xenotransplantation. Virology 2004; 325:18-23. Important new technique for reducing PERV expression in pig cells.
-
(2004)
Virology
, vol.325
, pp. 18-23
-
-
Karlas, A.1
Kurth, R.2
Denner, J.3
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