Does exposure to swine leukocyte antigens after pig-to-nonhuman primate xenotransplantation provoke antibodies that cross-react with human leukocyte antigens?

Xenotransplantation

Volumn 11, Issue 5, 2004, Pages 452-456

  Key, Tim ^a,c   Schurman, Henk Jan ^b   Taylor, Craig J ^a  

^a CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^b Immerge Biotherapeutics Inc   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Anti Gal antibody; Anti HLA antibody; Anti SLA antibody; Cynomolgus monkey; HDAF transgenic pigs; Pig to primate kidney transplantation; Sensitization

Indexed keywords

CROSS REACTING ANTIBODY; DECAY ACCELERATING FACTOR; GALACTOSYLGALACTOSE ANTIBODY; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; IMMUNOGLOBULIN G; LEUKOCYTE ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; AUTOPSY; CONTROLLED STUDY; CROSS REACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; KIDNEY TRANSPLANTATION; MONKEY; NONHUMAN; PRIMATE; PRIORITY JOURNAL; SWINE; TRANSGENIC ANIMAL; XENOTRANSPLANTATION;

ANIMALS; ANTIBODIES, HETEROPHILE; ANTIBODY SPECIFICITY; CROSS REACTIONS; DISACCHARIDES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; HLA ANTIGENS; HUMANS; IMMUNOGLOBULIN G; KIDNEY TRANSPLANTATION; MACACA FASCICULARIS; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 4344627573     PISSN: 0908665X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3089.2004.00167.x     Document Type: Article

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