αvβ6 integrin down-regulates the MMP-13 expression in oral squamous cell carcinoma cells

Experimental Cell Research

Volumn 309, Issue 2, 2005, Pages 273-283

  Ylipalosaari, M ^a   Thomas, G J ^b   Nystrom, M ^b   Salhimi, S ^b   Marshall, J F ^b   Huotari, V ^c   Tervahartiala, T ^d   Sorsa, T ^d   Salo, T ^a  

^a UNIVERSITY OF OULU   (Finland)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c OULU UNIVERSITY HOSPITAL   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

Author keywords

MMP 13; Oral squamous cell carcinoma; Regulation; v 6 integrin

Indexed keywords

ALPHA5 INTEGRIN; COLLAGEN TYPE 1; COLLAGENASE 3; INTEGRIN ALPHA 5 BETA 6; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CELL CULTURE; COLLAGEN DEGRADATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; MALE; MOUTH CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SQUAMOUS CELL CARCINOMA; TONGUE CARCINOMA; TUMOR GROWTH;

EID: 24944581672     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2005.06.008     Document Type: Article

References (50)

1. H.L. Goel, and L.R. Languino Integrin signaling in cancer Cancer Treat. Res. 119 2004 15 31 (Review)
2. G.J. Thomas, M.P. Lewis, J.F. Marshall, and P.M. Speight AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells through up-regulation of matrix metalloproteinase-9 Int. J. Cancer 2 2001 641 650
3. D.M. Ramos, M. But, J. Regezi, B.L. Schmidt, A. Atakilit, D. Dang, D. Ellis, R. Jordan, and X. Li Expression of integrin beta 6 enhances invasive behavior in oral squamous cell carcinoma Matrix Biol. 1 2002 297 307
4. L.J. McCawley, and L.M. Matrisian Matrix metalloproteinases: they're not just for matrix anymore! Curr. Opin. Cell Biol. 3 2001 534 540 (Review)
5. C.M. Overall, and C. López-Otín Strategies for MMP inhibition in cancer: innovations for the post-trial era Nat. Rev., Cancer 2 2002 657 672 (Review)
6. A.H. Baker, D.R. Edwards, and G.M. Murphy Metalloproteinase inhibitors: biological actions and therapeutic opportunities J. Cell Sci. 115 2002 3719 3727 (Review)
7. G.J. Thomas, and P.M. Speight Cell adhesion molecules and oral cancer Crit. Rev. Oral Biol. Med. 12 2001 479 498 (Review)
8. B.L. Ziober, S.S. Silverman, and R.H. Kramer Jr. Adhesive mechanisms regulating invasion and metastasis in oral cancer Crit. Rev. Oral Biol. Med. 12 2001 499 510 (Review)
9. J.M. Breuss, J. Gallo, H.M. Aldape, K. DeLisser, I.V. Klimanskaya, H.G. Folkesson, J.F. Pittet, S.L. Nishimura, D.V. Landers, W. Carpenter, N. Gillett, and D. Sheppard Expression of the beta 6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodelling J. Cell Sci. 108 1995 2241 2251
10. J. Jones, F.M. Watt, and P.M. Speight Changes in the expression of alpha v integrins in oral squamous cell carcinomas J. Oral Pathol. Med. 26 1997 63 68
11. M. Agrez, A. Chen, R.I. Cone, R. Pytela, and D. Sheppard The alpha v beta 6 integrin promotes proliferation of colon carcinoma cells through a unique region of the beta 6 cytoplasmic domain J. Cell Biol. 127 1994 547 556
12. J. Niu, X. Gu, J. Turton, C. Meldrum, E.W. Howard, and M. Agrez Integrin-mediated signalling of gelatinase B secretion in colon cancer cells Biochem. Biophys. Res. Commun. 249 1998 287 291
13. N. Ahmed, F. Pansino, R. Clyde, P. Murthi, M.A. Quinn, G.E. Rice, M.V. Agrez, S. Mok, and M.S. Baker Overexpression of alpha(v)beta6 integrin in serous epithelial ovarian cancer regulates extracellular matrix degradation via the plasminogen activation cascade Carcinogenesis 23 2002 237 244
14. G.J. Thomas, M.P. Lewis, S.A. Whawell, A. Russell, D. Sheppard, I.R. Hart, P.M. Speight, and J.F. Marshall Expression of the alphavbeta6 integrin promotes migration and invasion in squamous carcinoma cells J. Invest. Dermatol. 117 2001 67 73
15. D. Dang, Y. Yang, X.A. Li, A. Atakilit, J. Regezi, D. Eisele, D. Ellis, and D.M. Ramos Matrix metalloproteinases and TGFbeta1 modulate oral tumor cell matrix Biochem. Biophys. Res. Commun. 316 2004 937 942
16. G.J. Thomas, I.R. Hart, P.M. Speight, and J.F. Marshall Binding of TGF-beta1 latency-associated peptide (LAP) to alpha(v)beta6 integrin modulates behaviour of squamous carcinoma cells Br. J. Cancer 87 2002 859 867
17. U. Bergmann, J. Michaelis, R. Oberhoff, V. Knäuper, R. Beckmann, and H. Tschesche Enzyme linked immunosorbent assays (ELISA) for the quantitative determination of human leukocyte collagenase and gelatinase J. Clin. Chem. Clin. Biochem. 27 1989 349 351
18. J. Michaelis, M.C. Vissers, and C.C. Winternbourn Human neutrophil collagenase cleaves alpha 1-antitrypsin Biochem. J. 270 1990 809 814
19. H. Palosaari, J. Wahlgren, M. Larmas, H. Rönkä, T. Sorsa, T. Salo, and L. Tjäderhane The expression of MMP-8 in human odontoblasts and dental pulp cells is down-regulated by TGF-β1 J. Dent. Res. 79 2000 77 84
20. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 277 1970 680 685
21. G.W. Oliver, J.D. Leferson, W. Stetler-Stevenson, and D. Kleiner Quantitative reverse zymography: analysis of picogram amounts of metalloproteinase inhibitors using gelatinase A and B reverse zymograms Anal. Biochem. 244 1997 161 166
22. M. Mäkelä, T. Salo, V.J. Uitto, and H. Larjava Matrix metalloproteinases (MMP-2 and MMP-9) of the oral cavity: cellular origin and relationship to periodontal status J. Dent. Res. 73 1994 1397 1406
23. R. Hanemaaijer, T. Sorsa, Y.T. Konttinen, Y. Ding, M. Sutinen, H. Visser, V.W.M. van Hinsbergh, T. Helaakoski, T. Kainulainen, H. Rönkä, H. Tschesche, and T. Salo Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells. Regulation by tumor necrosis factor-alpha and doxycycline J. Biol. Chem. 272 1997 31504 31509
24. P.H. Weinreb, K.J. Simon, P. Rayhorn, W.J. Yang, D.R. Leone, B.M. Dolinski, B.R. Pearse, Y. Yokota, H. Kawakatsu, A. Atakilit, D. Sheppard, and S.M. Violette Function-blocking integrin alphavbeta6 monoclonal antibodies: distinct ligand-mimetic and nonligand-mimetic classes J. Biol. Chem. 279 2004 17875 17887
25. N. Dalvi, G.J. Thomas, J.F. Marshall, M. Morgan, R. Bass, V. Ellis, P.M. Speight, and S.A. Whawell Modulation of the urokinase-type plasminogen activator receptor by the beta6 integrin subunit Biochem. Biophys. Res. Commun. 317 2004 92 99
26. H. Xue, A. Atakilit, W. Zhu, X. Li, D.M. Ramos, and R. Pytela Role of the alpha(v)beta6 integrin in human oral squamous cell carcinoma growth in vivo and in vitro Biochem. Biophys. Res. Commun. 288 2001 610 618
27. J.A. Regezi, D.M. Ramos, R. Pytela, N.P. Dekker, and R.C.K. Jordan Tenascin and beta 6 integrin are overexpressed in floor of mouth in situ carcinomas and invasive squamous cell carcinomas Oral Oncol. 38 2004 332 336
28. S. Hamidi, T. Salo, T. Kainulainen, J. Epstein, K. Lerner, and H. Larjava Expression of alpha(v)beta6 integrin in oral leukoplakia Br. J. Cancer 82 2000 1433 1440
29. K. Arihiro, M. Kaneko, S. Fujii, K. Inai, and Y. Yokosaki Significance of alpha 9 beta 1 and alpha v beta 6 integrin expression in breast carcinoma Breast Cancer 7 2000 19 26
30. M.R. Morgan, G.J. Thomas, A. Russell, I.R. Hart, and J.F. Marshall The integrin cytoplasmic-tail motif EKQKVDLSTDC is sufficient to promote tumor cell invasion mediated by matrix metalloproteinase (MMP)-2 or MMP-9 J. Biol. Chem. 279 2004 26533 26539
31. D.G. Morris, X. Huang, N. Kaminski, Y. Wang, S.D. Shapiro, G. Dolganov, A. Glick, and D. Sheppard Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes MM P 12-dependent emphysema Nature 422 2003 169 173
32. M. Sutinen, T. Kainulainen, T. Hurskainen, E. Vesterlund, J.P. Alexander, C.M. Overall, T. Sorsa, and T. Salo Expression of matrix metalloproteinases (MMP-1 and -2) and their inhibitors (TIMP-1, -2 and -3) in oral lichen planus, dysplasia, squamous cell carcinoma and lymph node metastasis Br. J. Cancer 77 1998 2239 2245
33. M. Moilanen, E. Pirilä, R. Grenman, T. Sorsa, and T. Salo Expression and regulation of collagenase-2 (MMP-8) in head and neck squamous cell carcinomas J. Pathol. 197 2002 72 81
34. M. Nagata, H. Fujita, H. Ida, H. Hoshina, T. Inoue, Y. Seki, M. Ohnishi, T. Ohyama, S. Shingaki, M. Kaji, T. Saku, and R. Takagi Identification of potential biomarkers of lymph node metastasis in oral squamous cell carcinoma by cDNA microarray analysis Int. J. Cancer 106 2003 683 689
35. S. Kurahara, M. Shinohara, M. Beppu, A. Hiraki, H. Takeuchi, and K. Shirasuna Expression of MMPS, MT-MMP, and TIMPs in squamous cell carcinoma of the oral cavity: correlations with tumor invasion and metastasis Head Neck 21 1999 627 638
36. P. O-charoenrat, P.H. Rhys-Evans, and S.A. Eccles Expression of matrix metalloproteinases and their inhibitors correlates with invasion and metastasis in squamous cell carcinoma of the head and neck Arch. Otolaryngol., Head Neck Surg. 127 2001 813 820
37. M. Agrez, X. Gu, J. Turton, C. Meldrum, J. Niu, T. Antalis, and E.W. Howard The alpha v beta 6 integrin induces gelatinase B secretion in colon cancer cells Int. J. Cancer 81 1999 90 97
38. N. Johansson, K. Airola, R. Grenman, A.L. Kariniemi, U. Saarialho-Kere, and V.M. Kähäri Expression of collagenase-3 (matrix metalloproteinase-13) in squamous cell carcinomas of the head and neck Am. J. Pathol. 151 1997 499 508
39. U. Impola, V.J. Uitto, J. Hietanen, L. Häkkinen, L. Zhang, H. Larjava, K. Isaka, and U. Saarialho-Kere Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer J. Pathol. 202 2004 14 22
40. A.M. Pendás, J.A. Uría, M.G. Jiménez, M. Balbín, J.P. Freije, and C. López-Otín Expression and regulation of collagenase-3 (MMP-13) in human malignant tumors APMIS 107 2000 45 53 (Review)
41. M. Balbín, A. Fueyo, A. Tester, A.M. Pendás, A.S. Pitiot, A. Astudillo, C.M. Overall, S.D. Shapiro, and C. López-Otín Loss of collagenase-2 confers increased skin tumor susceptibility to male mice Nat. Genet. 35 2004 252 257
42. C.A. Owen, Z. Hu, C. López-Otín, and S.D. Shapiro Membrane-bound matrix metalloproteinase-8 on activated polymorphonuclear cells is a potent, tissue inhibitor of metalloproteinase-resistant collagenase and serpinase J. Immunol. 172 2004 7791 7803
43. V. Montel, J. Kleeman, D. Agarwal, D. Spinella, K. Kawai, and D. Tarin Altered metastatic behavior of human breast cancer cells after experimental manipulation of matrix metalloproteinase 8 gene expression Cancer Res. 64 2004 1687 1694
44. R. Ala-aho, M. Ahonen, S.J. George, J. Heikkilä, R. Grénman, M. Kallajoki, and V.M. Kähäri Targeted inhibition of human collagenase-3 (MMP-13) expression inhibits squamous cell carcinoma growth in vivo Oncogene 23 2004 5111 5123
45. C.B. Forsyth, J. Pulai, and R.F. Loeser Fibronectin fragments and blocking antibodies to alpha2beta1 and alpha5beta1 integrins stimulate mitogen-activated protein kinase signaling and increase collagenase 3 (matrix metalloproteinase 13) production by human articular chondrocytes Arthritis Rheum. 46 2002 2368 2376
46. J.S. Munger, X. Huang, H. Kawakatsu, M.J.D. Griffiths, S.L. Dalton, J. Wu, J.F. Pittet, N. Kaminski, C. Garat, M.A. Matthay, D.B. Rifkin, and D. Sheppard The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis Cell 96 1999 319 328
47. V. Knäuper, H. Will, C. López-Otín, B. Smith, S.J. Atkinson, H. Stanton, R.M. Hembry, and G. Murphy Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme J. Biol. Chem. 271 1996 17124 17131
48. J.M. Holopainen, J.A. Moilanen, T. Sorsa, M. Kivelä-Rajamäki, T. Tervahartiala, M.H. Vesaluoma, and T.M. Tervo Activation of matrix metalloproteinase-8 by membrane type 1-MMP and their expression in human tears after photorefractive keratectomy Invest. Ophthalmol. Visual Sci. 44 2003 2550 2556
49. L. Bailey, D. Wienke, M. Howard, V. Knäuper, C.M. Isacke, and G. Murphy Investigation of the role of Endo180/urokinase-type plasminogen activator receptor-associated protein as a collagenase 3 (matrix metalloproteinase 13) receptor Biochem. J. 363 2002 67 72
50. World Health Organization J.J. Pindborg P.A. Reichart C.J Smith I. vand der Waal Histological Typing of Cancer and Precancer of the Oral Mucosa Second edition 1997 Springer-Verlag Berlin