Investigation of the role of Endo180/urokinase-type plasminogen activator receptor-associated protein as a collagenase 3 (matrix metalloproteinase 13) receptor

Biochemical Journal

Volumn 363, Issue 1, 2002, Pages 67-72

  Bailey, Louise ^a   Wienke, Dirk ^a   Howard, Matthew ^a   Knäuper, Vera ^a   Isacke, Clare M ^a   Murphy, Gillian ^a  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

MMP 13; MT1 MMP; UPA; UPAR

Indexed keywords

CELL MEMBRANES; CELLS; PRECIPITATION (CHEMICAL);

IMMUNOLOCALIZATION;

PROTEINS;

COLLAGENASE 3; GLYCOPROTEIN; LIGAND; LOW DENSITY LIPOPROTEIN RECEPTOR; MANNOSE RECEPTOR; MATRIX METALLOPROTEINASE 14; PROCOLLAGENASE; RECEPTOR; RECEPTOR PROTEIN; UROKINASE RECEPTOR;

ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; ENZYME BINDING; FIBROSARCOMA; HUMAN; HUMAN CELL; IMMUNOLOCALIZATION; IMMUNOPRECIPITATION; INTERNALIZATION; MACROPHAGE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BINDING; TUMOR CELL LINE;

BLOTTING, WESTERN; CELL LINE; COLLAGENASES; DNA, COMPLEMENTARY; HUMANS; LIGANDS; MATRIX METALLOPROTEINASE 13; MICROSCOPY, FLUORESCENCE; OSTEOBLASTS; PRECIPITIN TESTS; PROTEIN BINDING; RECEPTORS, CELL SURFACE; RECEPTORS, MITOGEN; RNA, MESSENGER; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0036534413     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3630067     Document Type: Article

References (16)

1. Cellular mechanisms for human procollagenase 3 (MMP 13) activation. Evidence that MT1-MMP (MMP.14) and gelatinase A (MMP-2) are able to generate active enzyme
2. The role of the C-terminal domain of human collagenase-3 (MMP-13) in the activation of procollagenase 3, substrate specificity, and tissue inhibitor of metalloproteinase interaction
3. Induction of matrix metalloproteinase activation cascades based on membrane-type 1 matrix metalloproteinase: Associated activation of gelatinase A, gelatinase B and collagenase 3
4. Regulation of the collagenase-3 receptor and its role in intracellular ligand processing in rat osteoblastic cells
5. Collagenase-3 binds to a specific receptor, and requires the low density lipoprotein receptor-related protein for internalisation
6. p180, a novel recycling transmembrane glycoprotein with restricted cell type expression
7. Endo180, an endocytic recycling glycoprotein related to the macrophage mannose receptor is expressed on fibroblasts, endothelial cells and macrophages and functions as a lectin receptor
8. Characterisation of a novel member of the macrophage mannose receptor type C lectin family
9. A urokinase receptor-associated protein with specific collagen binding properties
10. The urokinase receptor associated protein (uPARAP/Endo180): A novel internalization receptor connected to the plasminogen activation system
11. The urokinase plasminogen activator receptor-associated protein/endo180 is coexpressed with its interaction partners urokinase plasminogen activator receptor and matrix metalloproteinase-13 during osteogenesis
12. Expression of recombinant membrane-type MMPs
13. Biochemical characterization of human collagenase-3
14. Identification of a specific receptor for interstitial collagenase on osteoblastic cells
15. Membrane type 1 matrix metalloproteinase and gelatinase A synergistically degrade type 1 collagen in a cell model