Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by gram-negative sepsis: Studies in p47phox-/- and gp91phox-/- mice

Journal of Immunology

Volumn 168, Issue 8, 2002, Pages 3974-3982

  Gao, Xiao Pei ^a   Standiford, Thedodore J ^a   Rahman, Arshad ^a   Newstead, Michael ^a   Holland, Steven M ^a   Dinauer, Mary C ^a   Liu, Qing Hui ^a   Malik, Asrar B ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; GLYCOPROTEIN; GLYCOPROTEIN GP 91; MACROPHAGE INFLAMMATORY PROTEIN 2; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; ENZYME MECHANISM; ESCHERICHIA COLI; GRAM NEGATIVE SEPSIS; KNOCKOUT MOUSE; LUNG INJURY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY BURST;

EID: 0037090069     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.8.3974     Document Type: Article

References (49)

1. 2 integrin-dependent mechanism
2. Increased endothelial permeability after neutrophil activation occurs by a diffusion-dependent mechanism
3. Vascular endothelial adhesion molecules and tissue inflammation
4. Adhesion molecules and cellular biomechanical changes in acute lung injury: Giles F. Filley lecture
5. phox-/- mice: Implications for fungal pathogenicity and host defense in chronic granulomatous disease
6. Role of oxygen radicals generated by NADPH oxidase in apoptosis induced in human leukemia cells
7. Interactions between the components of the human NADPH oxidase: A review about the intrigues in the phox family
8. National Institutes of Health conference: Recent advances in chronic granulomatous disease
9. Effect of the NADPH oxidase inhibitor apocynin on ischemia-reperfusion lung injury
10. phox mouse knockout model of chronic granulomatous disease
11. Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production
12. phox: Beyond the endothelium
13. phox is the heme binding subunit of the superoxide-generating NADPH oxidase
14. Redox-dependent signal transduction
15. phox: An essential component of NADPH oxidase
16. phox-/- mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs
17. Absence of respiratory burst in X-linked chronic granulomatous disease mice leads to abnormalities in both host defense and inflammatory response to Aspergillus fumigatus
18. Differential role of CD18 integrins in mediating lung neutrophil sequestration and increased microvascular permeability induced by Escherichia coli in mice
19. Abnormal regulation of inflammatory skin responses in male patients with chronic granulomatous disease
20. phox-/- mice
21. Neutralization of IL-10 increases lethality in endotoxemia: Cooperative effects of macrophage inflammatory protein-2 and TNF
22. Bacterial clearance and survival are dependent on CXC chemokine receptor-2 ligands in a murine model of pulmonary Nocardia asteroides infection
23. Neutralization of macrophage inflammatory protein-2 attenuates neutrophil recruitment and bacterial clearance in murine Klebsiella pneumonia
24. Chemokine-dependent neutrophil recruitment in a murine model of Legionella pneumonia: Potential role of neutrophils as immunoregulatory cells
25. Dopamine transporter-immunoreactive neurons decrease with age in the human substantia nigra
26. Accurate quantification of cells recovered by bronchoalveolar lavage
27. Neutralization of IL-10 increases survival in a murine model of Klebsiella pneumonia
28. In vivo inhibition of NF-κB activation prevents inducible nitric oxide synthase expression and systemic hypotension in a rat model of septic shock
29. Protein kinase C-ζ mediates TNF-α-induced ICAM-1 gene transcription in endothelial cells
30. Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1
31. Reversibility of increased microvessel permeability in response to VE-cadherin disassembly
32. Abrogation of thrombin-induced increase in pulmonary microvascular permeability in PAR-1 knockout mice
33. Tumor necrosis factor mediates experimental pulmonary edema by ICAM-1 and CD18-dependent mechanisms
34. Pulmonary microvascular responses to arachidonic acid in isolated perfused guinea pig lung
35. 2-integrin blockade driven by E-selectin promoter prevents neutrophil sequestration and lung injury in mice
36. Evidence for role of hydroxyl radical in complement and neutrophil-dependent tissue injury
37. phox-/- mouse model of chronic granulomatous disease
38. Regulation of macrophage chemokine expression by lipopolysaccharide in vitro and in vivo
39. CXC chemokine receptor CXCR2 is essential for protective innate host response in murine Pseudomonas aeruginosa pneumonia
40. Inhibition of pulmonary neutrophil trafficking during endotoxemia is dependent on the stimulus for migration
41. Inhibition of alveolar neutrophil immigration in endotoxemia is macrophage inflammatory protein 2 independent
42. Regulation of early peritoneal neutrophil migration by macrophage inflammatory protein-2 and mast cells in experimental peritonitis
43. The effects of granulocyte colony-stimulating factor and neutrophil recruitment on the pulmonary chemokine response to intratracheal endotoxin
44. Macrophage inflammatory protein-2 is a mediator of polymorphonuclear neutrophil influx in ocular bacterial infection
45. Increased superoxide anion release from human endothelial cells in response to cytokines
46. In vitro and in vivo dependency of chemokine generation on C5a and TNF-α
47. Soluble ICAM-1 activates lung macrophages and enhances lung injury
48. Impaired pulmonary NF-κB activation in response to lipopolysaccharide in NADPH oxidase-deficient mice
49. NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease