Retinoid X receptor γ is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina

Investigative Ophthalmology and Visual Science

Volumn 46, Issue 8, 2005, Pages 2897-2904

  Roberts, Melanie R ^a   Hendrickson, Anita ^a   McGuire, Christopher R ^a   Reh, Thomas A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OPSIN; RETINOID X RECEPTOR GAMMA; THYROID HORMONE RECEPTOR BETA; SHORT WAVELENGTH OPSIN; SHORT-WAVELENGTH OPSIN;

ANIMAL TISSUE; ARTICLE; DOWN REGULATION; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA; RETINA CONE; ANIMAL; C57BL MOUSE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; IN SITU HYBRIDIZATION; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; POLYMERASE CHAIN REACTION;

ANIMALS; CONES (RETINA); FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; IN SITU HYBRIDIZATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OPSIN; POLYMERASE CHAIN REACTION; RETINA; RETINOID X RECEPTOR GAMMA; THYROID HORMONE RECEPTORS BETA;

EID: 24644470128     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.05-0093     Document Type: Article

References (38)

1. McKenna NJ, O'Malley BW. Combinatorial control of gene expression by nuclear receptors and coregulators. Cell. 2002;108:465-474.
2. Chiang MY, Misner D, Kempermann G, et al. An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression. Neuron. 1998;21:1353-1361.
3. Saga Y, Kobayashi M, Ohta H, et al. Impaired extrapyramidal function caused by the targeted disruption of retinoid X receptor RXRgamma1 isoform. Genes Cells. 1999;4:219-228.
4. Kastner P, Grondona JM, Mark M, et al. Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis. Cell. 1994;78:987-1003.
5. Dolle P, Fraulob V, Kastner P, Chambon P. Developmental expression of murine retinoid X receptor (RXR) genes. Mech Dev. 1994; 45:91-104.
6. Mon M, Ghyselinck NB, Chambon P, Mark M. Systematic immunolocalization of retinoid receptors in developing and adult mouse eyes. Invest Ophthalmol Vis Sci. 2001;42:1312-1318.
7. Krezel W, Ghyselinck N, Samad TA, et al. Impaired locomotion and dopamine signaling in retinoid receptor mutant mice. Science. 1998;279:863-867.
8. Samad TA, Krezel W, Chambon P, Borrelli E. Regulation of dopaminergic pathways by retinoids: activation of the D2 receptor promoter by members of the retinoic acid receptor-retinoid X receptor family. Proc Natl Acad Sci USA. 1997;94:14349-14354.
9. Luria A, Furlow JD. Spatiotemporal retinoid-X receptor activation detected in live vertebrate embryos. Proc Natl Acad Sci USA. 2004;101:8987-8992.
10. Hoover F, Seleiro EA, Kielland A, Brickell PM, Glover JC. Retinoid X receptor gamma gene transcripts are expressed by a subset of early generated retinal cells and eventually restricted to photoreceptors. J Comp Neurol. 1998;391:204-213.
11. Ng L, Hurley JB, Dierks B, et al. A thyroid hormone receptor that is required for the development of green cone photoreceptors. Nat Genet. 2001;27:94-98.
12. Szel A, Rohlich P, Caffe AR, van Veen T. Distribution of cone photoreceptors in the mammalian retina. Microsc Res Tech. 1996; 35:445-462.
13. Xiao M, Hendrickson A. Spatial and temporal expression of short, long/medium, or both opsins in human fetal cones. J Comp Neurol. 2000;425:545-559.
14. Bumsted K, Hendrickson A. Distribution and development of short-wavelength cones differ between Macaca monkey and human fovea. J Comp Neurol. 1999:403:502-516.
15. Applebury ML, Antoch MP, Baxter LC, et al. The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning. Neuron. 2000;27:513-523.
16. Kubota R, McGuire C, Dierks B, Reh TA. Identification of ciliary epithelial-specific genes using subtractive libraries and cDNA arrays in the avian eye. Dev Dyn. 2004;229:529-540.
17. Janssen JJ, Kuhlmann ED, van Vugt AH, et al. Retinoic acid receptors and retinoid X receptors in the mature retina: subtype determination and cellular distribution. Curr Eye Res. 1999;19:338-347.
18. Carter-Dawson LD, LaVail MM. Rods and cones in the mouse retina. II. Autoradiographic analysis of cell generation using tritiated thymidine. J Comp Neurol. 1979;188:263-272.
19. Milam AH, Hendrickson AE, Xiao M, et al. Localization of tubby-like protein 1 in developing and adult human retinas. Invest Ophthalmol Vis Sci. 2000;41:2352-2356.
20. Cornish EE, Xiao M, Yang Z, Provis JM, Hendrickson AE. The role of opsin expression and apoptosis in determination of cone types in human retina. Exp Eye Res. 2004;78:1143-1154.
21. Zhang XK, Hoffmann B, Tran PB, Graupner G, Pfahl M. Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors. Nature. 1992;355:441-446.
22. Sjoberg M, Vennstrom B. Ligand-dependent and -independent transactivation by thyroid hormone receptor beta 2 is determined by the structure of the hormone response element. Mol Cell Biol. 1995;15:4718-4726.
23. Puzianowska-Kuznicka M, Damjanovski S, Shi YB. Both thyroid hormone and 9-cis retinoic acid receptors are required to efficiently mediate the effects of thyroid hormone on embryonic development and specific gene regulation in Xenopus laevis. Mol Cell Biol. 1997;17:4738-4749.
24. Campos-Barros A, Erway LC, Krezel W, et al. Absence of thyroid hormone receptor beta-retinoid X receptor interactions in auditory function and in the pituitary-thyroid axis. Neuroreport. 1998;9:2933-2937.
25. Hatakeyama J, Kageyama R. Retinal cell fate determination and bHLH factors. Semin Cell Dev Biol. 2004;15:83-89.
26. Bumsted O'Brien KM, Cheng H, Jiang Y, Schulte D, Swaroop A, Hendrickson AE. Expression of photoreceptor-specific nuclear receptor NR2E3 in rod photoreceptors of fetal human retina. Invest Ophthalmol Vis Sci. 2004;45:2807-2812.
27. Cheng H, Khanna H, Oh EC, Hicks D, Mitton KP, Swaroop A. Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors. Hum Mol Genet. 2004; 13:1563-1575.
28. Milam AH, Rose L, Cideciyan AV, et al. The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration. Proc Natl Acad Sci USA. 2002;99:473-478.
29. Haider NB, Jacobson SG, Cideciyan AV, et al. Mutation of a nuclear receptor gene, NR2E3, causes enhanced S cone syndrome, a disorder of retinal cell fate. Nat Genet. 2000;24:127-131.
30. Haider NB, Naggert JK, Nishina PM. Excess cone cell proliferation due to lack of a functional NR2E3 causes retinal dysplasia and degeneration in rd7/rd7 mice. Hum Mol Genet. 2001;10:1619-1626.
31. Mears AJ, Kondo M, Swain PK, et al. Nrl is required for rod photoreceptor development. Nat Genet. 2001;29:447-452.
32. Heyman RA, Mangelsdorf DJ, Dyck JA, et al. 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell. 1992;68:397-406.
33. de Urquiza AM, Liu S, Sjoberg M, et al. Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. Science. 2000; 290:2140-2144.
34. McCaffery P, Lee MO, Wagner MA, Sladek NE, Drager UC. Asymmetrical retinoic acid synthesis in the dorsoventral axis of the retina. Development. 1992;115:371-382.
35. McCaffery P, Posch KC, Napoli JL, Gudas L, Drager UC. Changing patterns of the retinoic acid system in the developing retina. Dev Biol. 1993;158:390-399.
36. Cook T, Desplan C. Photoreceptor subtype specification: from flies to humans. Semin Cell Dev Biol. 2001;12:509-518.
37. Oro AE, McKeown M, Evans RM. The Drosophila retinoid X receptor homolog ultraspiracle functions in both female reproduction and eye morphogenesis. Development. 1992;115:449-462.
38. Zelhof AC, Ghbeish N, Tsai C, Evans RM, McKeown M. A role for ultraspiracle, the Drosophila RXR, in morphogenetic furrow movement and photoreceptor cluster formation. Development. 1997; 124:2499-2506.