Retinoic acid receptors and retinoid X receptors in the mature retina: Subtype determination and cellular distribution

Current Eye Research

Volumn 19, Issue 4, 1999, Pages 338-347

  Janssen, Jacques J M ^a,b   Kuhlmann, Eleonoor D ^a   Van Vugt, Anke H M ^a   Winkens, Huub J ^a   Janssen, Bert P M ^a   Deutman, August F ^a   Driessen, Carola A G G ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Retina; Retinoic acid; Retinoic acid receptors; Retinoid X receptors; Visual cycle

Indexed keywords

DNA FRAGMENT; RECEPTOR SUBTYPE; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR;

ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; GENE AMPLIFICATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOTORECEPTOR CELL; PRIORITY JOURNAL; RAT; RECEPTOR GENE; RETINA; RETINA CELL; RETINA CONE; RETINA ROD; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0032746184     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.19.4.338.5307     Document Type: Article

References (44)

1. Bok D. The retinal pigment epithelium: a versatile partner in vision. J Cell Sci. 1993;17:189-195.
2. Simon A, Hellman U, Wernstedt C, Eriksson U. The retinal pigment epithelial-specific 11-cis retinol dehydrogenase belongs to the family of short chain alcohol dehydrogenases. J Biol Chem. 1995;270:1107-1112.
3. Driessen CAGG, Janssen APM, Winkens HJ, van Vugt AHM, de Leeuw ALM and Janssen JJM. Cloning and expression of a cDNA encoding bovine retinal pigment epithelial 11-cis retinol dehydrogenase. Invest Ophthalmol Vis Sci. 1995;36: 1988-1996.
4. Simon A, Lagercrantz J, Bajalica-Lagercrantz S, Eriksson U. Primary structure of human 11-cis retinol dehydrogenase and organization and chromosomal localization of the corresponding gene. Genomics. 1996;36:424-430.
5. Driessen CAGG, Winkens HJ, Deutman AF, Janssen JJM. Analysis of the mouse gene encoding retinal pigment epithelial 11- cis retinol dehydrogenase. Invest Ophthalmol Vis Sci. 1997; 38 (suppl. 3): S305.
6. Driessen CAGG, Winkens HJ, Kuhlmann ED, Janssen APM, van Vugt AHM, Deutman AF, Janssen JJM. The visual cycle retinol dehydrogenase: possible involvement in the 9-cis biosynthetic pathway. FEBS Lett. 1998; 428:135-140.
7. Giguere V, Ong ES, Evans RM. Identification of a receptor for the morphogen retinoic acid. Nature. 1987; 330:624-629.
8. Brand N, Petkovich M, Krust A, Chambon P, DeThe H, Marchio A, Tiollas P, Dejean A. Identification of a second human retinoic acid receptor. Nature. 1988:332:850-853.
9. Krust A, Kastner P, Petkovich M, Zelent A, Chambon P. A third human retinoic acid receptor. Proc Natl Acad Sci. 1989;86:5310-5314.
10. Mangelsdorf DJ, Ong ES, Dyck JA, Evans RM. Nuclear receptor that identifies a novel retinoic acid-response pathway. Nature. 1990;345:224-229.
11. Levin AA, Sturzenbecker LJ, Kazmer S, Bosakowski T, Huselton C, Allenby G, Speck, J, Kratzeisen C, Rosenberger M, Lovey A, Grippo JF. 9-cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα. Nature. 1992;355:359-361.
12. Heyman RA, Mangelsdorf DJ, Dydi JA, Stein RB, Eichele G, Evans RM, Thaller C. 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell. 1992; 68:397-406.
13. Kastner P, Chambon P, Leid M. Role of nuclear retinoic acid receptors in the regulation of gene expression. In Blomhoff R, ed. Vitamin A in Health and disease. New York: Marcel Dekker Inc; 1994:189-238.
14. Nagpal S, Friant S, Nakshatri H, Chambon P. RARs and RXRs evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo. EMBO J. 1993;12:2349-2360.
15. Mangelsdorf DJ, Evans RM. The RXR heterodimers and orphan receptors. Cell. 1995; 83:841-850.
16. Leroy A, Krust A, Zelent A, Mendolsohn C, Garnier J-M, Kastner P, Dierich A, Chambon P. Multiple isoforms of the mouse retinoic acid receptor a are generated by alternative splicing and differential induction by retinoic acid. EMBO J. 1991;10: 59-69.
17. Zelent A, Mendolsohn C, Kastner P, Krust A, Garnier J-M, Ruffenach F, Leroy A, Chambon P. Differentially expressed isoforms of the mouse retinoic acid receptor β are generated by usage of two promoters and alternative splicing. EMBO J. 1991;10:71-81.
18. Layer PG, Rothermel A, Hering H, Wolf B, DeGrip, WJ, Hicks D, Willbold E. Pigmented epithelium sustains cell proliferation and decreases expression of opsins and acetylcholinesterase in reaggregated chicken retinospheroids. Eur J Neurosci. 1997;9:1795-1803.
19. Rothermel A, Willbold E, DeGrip WJ, Layer PG. Pigmented epithelium induces complete retinal reconstitution from dispersed embryonic chick retinae in reaggregation culture. Proc R Soc Lond (Biol.). 1997;264:1293-1302.
20. McCaffery P, Posch KC, Napoli JL, Gudas L, Dräger UC. Changing patterns of the retinoic acid system in the developing retina. Dev Biol. 1993;158:390-399.
21. Dräger UC, McCaffery P. Retinoic acid and development of the retina. Prog Ret Eye Res. 1997;16:323-351.
22. Haytt G, Schmitt EA, Marsh-Amstrong NA, Dowling JE. Retinoic acid induced duplication of the zebrafish retina. Proc Natl Acad Sci. 1992;89:8293-8297.
23. Haytt G, Schmitt EA, Marsh-Amstrong N, McCaffery P, Dräger UC, Dowling JE. Retinoic acid establishes ventral retinal characteristics. Development. 1996;122:195-204.
24. Shenefelt RE. Morphogenesis of malformations in hamsters caused by retinoic acid. Teratology. 1972;5:403-418.
25. Li E, Sucov HM, Lee KF, Evans RM, Jaenisch R. Normal development and growth of mice carrying a targeted disruption of the al retinoic receptor gene. Proc Natl Acad Sci. 1993;90:1590-1594.
26. Lohnes D, Kastner P, Dierich A, Mark M, Lemeur M, Chambon P. Function of retinoic acid receptor γ in the mouse. Cell 1993;73:643-658.
27. Lufkin T, Lohnes D, Mark M, Dierich A, Gorry P, Gaub MP, LeMeur M, Chambon P. High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice Proc Natl Acad Sci. 1993;90:7225-7229.
28. Kastner P, Mark M, Chambon P. Nonsteroid nuclear receptors, what are genetic studies telling us about their role in real life? Cell. 1995;83:859-869.
29. McCaffery P, Mey J, Dräger UC. Light-mediated retinoic acid production. Proc Natl Acad Sci. 1996;93:12570-12574.
30. Kutty G, Duncan T, Nickerson JM, VanVeen T, Chader GJ, Wiggert B. Light deprivation profoundly affects gene expression of interphotoreceptor retinoid binding protein in the mouse eye. Exp Eye Res. 1994;58:65-75.
31. Auffray C, Rougeon F. Purification of mouse immunoglobulin heavy-chain messenger RNA's from total myeloma tumor RNA. Eur J Biochem. 1980;107:303-314.
32. Feinberg AP, Vogelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem. 1983;132:6-13.
33. Blanks JC, Johnson LV. Specific binding of peanut lectin to a class of retinal photoreceptors. Invest Ophthalmol Vis Sci. 1984;25:546-557.
34. Haq RU, Pfhal M, Chytil F. Retinoic acid affects the expression of nuclear retinoic acid receptors in tissues of retinol-deficient rats. Proc Natl Acad Sci 1991;88:8272-8276.
35. Giguere V. Retinoic acid receptors and cellular retinoid binding proteins: complex interplay in retinoid signaling. Endocrine Rev. 1994;15:61-79.
36. Hoover F, Seleiro EA, Kielland A, Brickell PM, Glover JC. Retinoid X receptor gamma gene transcripts are expressed by a subset of early generated retinal cells and eventually restricted to photoreceptors. J Comp Neurol. 1998;391:204-213.
37. Thompson PD, Jurutka PW, Haussler CA, Whitfield GK, Haussler MR. Heterodimeric DNA binding by the vitamin D receptor and retinoid X receptors is enhanced by 1,25-dihydroxyvitamin D3 and inhibited by 9-cis retinoic acid. Evidence for allosteric receptor interactions. J Biol Chem. 1998;273:8483-8491.
38. Johnson JA, Grande JP, Roche PC, Campbell RJ, Kumar R. Immuno-localization of the calcitriol receptor, calbindin-D28k and the plasma membrane calcium pump in the human eye. Curr Eye Res. 1995;14:101-108.
39. Weiler R, Schultz K, Pottek M, Janssen-Bienhold U. Retinoic acid has light-adaptive effects on horizontal cells in the retina. Proc Natl Acad Sci. 1998;95:7139-7144.
40. Pike J, Haussler MR. Association of 1,25-dihydroxy-vitamin D3 with cultured 3T6 mouse fibroblasts. Cellular uptake and receptor mediated migration to the nucleus. J Biol Chem. 1983;258:8554-8560.
41. Broekhuyse RM, Tolhuizen EF, Janssen AP, Winkens HJ. Light induced shift and binding of S-antigen in retinal rods. Curr Eye Res. 1985;4:613-618.
42. Kuo CH, Miki N. Translocation of a photoreceptor-specific MEKA protein by light. Neurosci Lett. 1989;103:8-10.
43. Terakita A, Takahama H, Tamotsu S, Suzuki T, Hariyama T, and Tsukahara Y. Light-modulated subcellular localization of the alpha-subunit of GTP-binding protein Gq in crayfish photoreceptors. Vis Neurosci. 1996;13:539-547.
44. Wang J, Chai X, Eriksson U, Napoli JL. Activity of the human 11-cis-retinol dehydrogenase (Rdh5) with steroids and retinoids and expression of its mRNA in extra-ocular human tissue. Biochem J. 1999;338:23-27.