Excess cone cell proliferation due to lack of a functional NR2E3 causes retinal dysplasia and degeneration in rd7/rd7 mice

Human Molecular Genetics

Volumn 10, Issue 16, 2001, Pages 1619-1626

  Haider, N B ^a   Naggert, J K ^a   Nishina, P M ^a  

^a JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; EOSIN; HEMATOXYLIN; RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INTERACTION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE MODEL; EMBRYO; EMBRYO DEVELOPMENT; EXON; EYE FUNDUS; FEMALE; GENE DELETION; GENE MUTATION; GENETIC ANALYSIS; GENETIC DISORDER; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTRON; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; OPHTHALMOSCOPY; PHENOTYPE; PHOTORECEPTOR CELL; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RETINA CONE; RETINA DEGENERATION; RETINA FOVEA; RETINA MALFORMATION; RNA SPLICING; STAINING; TISSUE SECTION;

ANIMALIA;

EID: 0035421442     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/10.16.1619     Document Type: Article

References (30)

1. Mouse fundus photography and angiography: A catalogue of normal and mutant phenotypes
2. A deletion in a photoreceptor-specific nuclear receptor mRNA causes retinal degeneration in the rd7 mouse
3. The steroid receptor superfamily: Mechanisms of diversity
4. Ligand-protein interactions in nuclear receptors of hormones
5. The structure of the nuclear hormone receptors
6. Structural elements of an orphan nuclear receptor-DNA complex
7. The control of ell fate in the embryonic visual system by atonal, tailless, and EGFR signaling
8. The Xenopus homologue of the Drosophila gene tailless has a function in early eye development
9. Identification of a photoreceptor cell-specific nuclear receptor
10. Mutation of a nuclear receptor gene, NR2E3, causes enhanced S cone syndrome, a disorder of retinal cell fate
11. SWS (blue) cone hypersensitivity in a newly identified retinal degeneration
12. Enhanced S cone syndrome: Evidence for an abnormally large number of S cones
13. Diagnostic clinical findings of a new syndrome with night blindness, maculopathy, and enhanced S cone sensitivity
14. Unique topographic separation of two spectral classes of cones in the mouse retina
15. Migration and synaptogenesis of cone photoreceptors in the developing mouse retina
16. Rods and cones in the mouse retina
17. Spatial and temporal differences between the expression of short-and middle-wave Sensitive cone pigments in the mouse retina
18. The murine cone photoreceptor: A single cone type expresses both S and M opsins with retinal spatial patterning
19. Retina-specific nuclear receptor: A potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Müller glial cells
20. The association of nonsense codons with exon skipping
21. Core LXXLL motif sequences in CBP, SRC1, and RIP140 define affinity and selectivity for steroid and retinoid receptors
22. The mouse homolog of the orphan nuclear receptor tailless is expressed in the developing forebrain
23. Topography of cone electrophysiology in the enhanced S cone syndrome
24. Ligands of steroid/thyroid receptors induce cone photoreceptors in vertebrate retina
25. A thyroid hormone receptor that is required for the development of green cone photoreceptors
26. An array of early differentiating cones precedes the emergence of the photoreceptor mosaic in the fetal monkey retina
27. Development of photoreceptor mosaics in primate retina
28. The development of photoreceptor-specific proteins in primate retina
29. Isolation of DNA from biological specimens without extraction with phenol
30. Cell-specific expression of tubby gene family members (tub, Tulp 1, 2, and 3) in the retina