Control of MAPK signalling: From complexity to what really matters

Oncogene

Volumn 24, Issue 36, 2005, Pages 5533-5542

  Hornberg, Jorrit J ^a   Binder, Bernd ^a,b   Bruggeman, Frank J ^a   Schoeberl, Birgit ^c   Heinrich, Reinhart ^b   Westerhoff, Hans V ^a,d  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b HUMBOLDT UNIVERSITY   (Germany)

^c MERRIMACK PHARMACEUTICALS   (United States)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Control analysis; Kinetic model; MAPK signalling; Systems biology

Indexed keywords

EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; CARCINOGENESIS; CONTROL; MUTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; COMPUTER SIMULATION; DRUG EFFECT; GENE EXPRESSION; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

COMPUTER SIMULATION; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; MAP KINASE SIGNALING SYSTEM; PHOSPHORYLATION;

EID: 24644456999     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1208817     Document Type: Article

References (54)

1. Asthagiri AR and Lauffenburger DA. (2001). Biotechnol. Prog., 17, 227-239.
2. Asthagiri AR, Reinhart CA, Horwitz AF and Lauffenburger DA. (2000). J. Cell Sci., 113 (Partt 24), 4499-4510.
3. Bakker BM, Michels PA, Opperdoes FR and Westerhoff HV. (1999). J. Biol. Chem., 274, 14551-14559.
4. Bhalla US and Iyengar R. (1999). Science, 283, 381-387.
5. Bos JL. (1989). Cancer Res., 49, 4682-4689.
6. Bruggeman F, Westerhoff H, Hoek J and Kholodenko B. (2002). J. Theor. Biol., 218, 507.
7. Bruggeman FJ, van Heeswijk WC, Boogerd FC and Westerhoff HV. (2000). Biol. Chem., 381, 965-972.
8. Buday L, Warne PH and Downward J. (1995). Oncogene, 11, 1327-1331.
9. Campbell SL, Khosravi-Far R, Rossman KL, Clark GJ and Der CJ. (1998). Oncogene, 17, 1395-1413.
10. Carpenter G. (2000). BioEssays, 22, 697-707.
11. Cascante M, Boros LG, Comin-Anduix B, de Atauri P, Centelles JJ and Lee PW. (2002). Nat. Biotechnol., 20, 243-249.
12. Cobb MH. (1999). Prog. Biophys. Mol. Biol., 71, 479-500.
13. Cook SJ, Aziz N and McMahon M. (1999). Mol. Cell. Biol., 19, 330-341.
14. Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR and Futreal PA. (2002). Nature, 417, 949-954.
15. Dong C, Waters SB, Holt KH and Pessin JE. (1996). J. Biol. Chem., 271, 6328-6332.
16. Fell DA. (1992). Biochem. J., 286, 313-330.
17. Groen AK, Wanders RJ, Westerhoff HV, van der Meer R and Tager JM. (1982). J. Biol. Chem., 257, 2754-2757.
18. Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW and Weinberg RA. (1999). Nature, 400, 464-468
19. Hanahan D and Weinberg RA. (2000). Cell, 100, 57-70.
20. Haugh JM, Huang AC, Wiley HS, Wells A and Lauffenburger DA. (1999). J. Biol. Chem., 274, 34350-34360.
21. Heinrich R, Neel BG and Rapoport TA. (2002). Mol. Cell, 9, 957-970.
22. Heinrich R and Rapoport TA. (1974). Eur. J. Biochem., 42, 89-95.
23. Hornberg JJ, Bruggeman FJ, Binder B, Geest CR, Bij de Vaate AJM, Lankelma J, Heinrich R and Westerhoff HV. (2005). FEBS J., 272, 244-258.
24. Hornberg JJ, Tijssen MR and Lankelma J. (2004). Eur. J. Biochem., 271, 3905-3913.
25. Hoshino R, Chatani Y, Yamori T, Tsuruo T, Oka H, Yoshida O, Shimada Y, Ari-i S, Wada H, Fujimoto J and Kohno M. (1999). Oncogene, 18, 813-822.
26. Huang CY and Ferrell Jr JE. (1996). Proc. Natl. Acad. Sci. USA, 93, 10078-10083.
27. Kacser H and Burns JA. (1973). Symp. Soc. Exp. Biol., 27, 65-104.
28. Keyse SM. (2000). Curr. Opin. Cell Biol., 12, 186-192.
29. Kholodenko BN and Westerhoff HV. (1993). FEBS Lett., 320, 71-74.
30. Kholodenko BN. (2000). Eur. J. Biochem., 267, 1583-1588.
31. Kholodenko BN, Demin OV, Moehren G and Hoek JB. (1999). J. Biol. Chem., 274, 30169-30181.
32. Kholodenko BN, Hoek JB and Westerhoff HV. (2000). Trends Cell Biol., 10, 173-178.
33. Lee E, Salic A, Kruger R, Heinrich R and Kirschner MW. (2003). pLoS Biol., 1, e10.
34. Lewis TS, Shapiro PS and Ahn NG. (1998). Adv. Cancer Res., 74, 49-139.
35. Magnuson NS, Beck T, Vahidi H, Hahn H, Smola U and Rapp UR. (1994). Semin. Cancer Biol., 5, 247-253.
36. Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K, Vande Woude GF and Ahn NG. (1994). Science, 265, 966-970.
37. Marshall CJ. (1995). Cell, 80, 179-185.
38. Millward TA, Zolnierowicz S and Hemmings BA. (1999). Trends Biochem. Sci., 24, 186-191.
39. Oksvold MP, Skarpen E, Wierod L, Paulsen RE and Huitfeldt HS. (2001). Eur. J. Cell Biol., 80, 285-294.
40. Pagès G, Lenormand P, L'Allemain G, Chambard JC, Meloche S and Pouyssegur J. (1993). Proc. Natl. Acad. Sci. USA, 90, 8319-8323.
41. Pedersen MW, Meltorn M, Damstrup L and Poulsen HS. (2001). Ann. Oncol., 12, 745-760.
42. Periwal V and Szallasi Z. (2002). Nat. Biotechnol., 20, 345-346.
43. Porfiri E and McCormick F. (1996). J. Biol. Chem., 271, 5871-5877.
44. Rapp UR, Goldsborough MD, Mark GE, Bonner TI, Groffen J, Reynolds Jr FH and Stephenson JR. (1983). Proc. Natl. Acad. Sci. USA, 80, 4218-4222.
45. Schoeberl B, Eichler-Jonsson C, Gilles ED and Muller G. (2002). Nat. Biotechnol., 20, 370-375.
46. Schuster R and Holzhutter HG. (1995). Eur. J. Biochem., 229, 403-418.
47. Sebolt-Leopold JS. (2000). Oncogene, 19, 6594-6599.
48. Snoep JL and Westerhoff HV. (2005). Curr. Genomics, 5, 687-697.
49. Teusink B, Passarge J, Reijenga CA, Esgalhado E, van der Weijden CC, Schepper M, Walsh MC, Bakker BM, van Dam K, Westerhoff HV and Snoep JL. (2000). Eur. J. Biochem., 267, 5313-5329.
50. Todd JL, Tanner KG and Denu JM. (1999). J. Biol. Chem., 274, 13271-13280.
51. Tombes RM, Auer KL, Mikkelsen R, Valerie K, Wymann MP, Marshall CJ, McMahon M and Dent P. (1998). Biochem. J., 330, 1451-1460.
52. Treisman R. (1996). Curr. Opin. Cell Biol., 8, 205-215.
53. Vogelstein B and Kinzler KW. (2004). Nat. Med., 10, 789-799.
54. Westerhoff HV and Van Dam K. (1987). Thermodynamics, Control of Biological Free-energy Transduction. Elsevier: Amsterdam.