HIV-1 exposed dendritic cells show increased pro-inflammatory cytokine production but reduced IL-1ra following lipopolysaccharide stimulation

AIDS

Volumn 13, Issue 15, 1999, Pages 2013-2021

  Loré, Karin ^a,b   Sönnerborg, Anders ^a   Olsson, Jenny ^a   Patterson, Bruce K ^c   Fehniger, Thomas E ^a   Perbeck, Leif ^b   Andersson, Jan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Cytokines; Dendritic cells; HIV replication; IL 1; Immunopathogenesis; TNF

Indexed keywords

CHEMOKINE; CYTOKINE; GAG PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ASSAY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL;

EID: 2442749666     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199910220-00003     Document Type: Article

References (36)

1. Granelli-Piperno A, Moser B, Pope M, et al. Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors. J Exp Med 1996, 184:2433-2438.
2. Blauvelt A, Asada H, Saville M, et al. Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways. J Clin Invest 1997, 100:2043-2053.
3. Pope M, Betjes MGH, Romani N, et al. Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1. Cell 1994, 78:389-398.
4. Pope M, Gezelter S, Gallo N, Hoffman L, Steinman R. Low levels of HIV-1 infection in cutaneous dendritic cells promote extensive viral replication upon binding to memory CD4+ T cells. J Exp Med 1995, 182:2045-2056.
5. Pope M, Elmore D, Ho D, Marx P. Dendrite cell-T cell mixtures, isolated from the skin and mucosae of macaques, support the replication of SIV. AIDS Res Hum Retroviruses 1997, 13:819-827.
6. Woods T, Roberts B, Butera S, Folks T. Loss of inducible virus in CD45RA naive cells after human munodeficiency virus-1 entry accounts for preferential viral replication in CD45RO memory cells. Blood 1997, 89:1635-1641.
7. Zocchi MR, Poggi A, Rubartelli A. The RGD-containing domain of exogenous HIV-1 Tat inhibits the engulfment of apoptotic bodies by dendritic cells. AIDS 1997, 11:1227-1235.
8. Romani N, Gruner S, Brang D, et al. Proliferating dendritic cell progenitors in human blood. J Exp Med 1994, 180:83-93.
9. Sallusto F, Lanziavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage-colony-stimulating factor plus interleukin 4 and down regulated by tumor necrosis factor α. J Exp Med 1994, 179:1109-1118.
10. Loré K, Sonnerborg A, Spetz AL, Andersson U, Andersson J. Immunocytochemical detection of cytokines and chemokines in Langerhans cells and in vitro derived dendritic cells [corrected and republished in J Immunol Meth 1998 Sep 1, 218:173-187] J Immunol Meth 1998, 214:97-111.
11. Patterson B, Jiyamapa D, Mayrand E, et al. Detection of HIV-1 DNA in cells and tissue by fluorescent in situ 5′-nuclease assay (FISNA). Nuc Acid Res 1996, 24:3656-3658.
12. Sander B, Andersson J, Andersson U. Assesment of cytokines by immunofluorecence and the paraformaldehyd-saponin procedure. Immunol Rev 1991, 119:65-93.
13. Björk L, Fehniger TE, Andersson U, Andersson J. Computerized assessment of production of multiple human cytokines at the single-cell level using image analysis. J Leucoc Biol 1996, 59:287-295.
14. Liu R, Paxton W, Choe S, et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996, 86:367-377.
15. Andersson J, Björk L, Dinarello C, Towbin H, Andersson U. Lipopolysaccharide induces human interleukin-1 receptor antagonist and interleukin-1 production in the same cell. Eur J Immunol 1992, 22:2617-2623.
16. Andersson J, Fehniger T, Patterson B, et al. Early reduction of immune activation in lymphoid tissue following highly active HIV therapy. AIDS 1998, 12:F123-F129.
17. Ghanekar S, Zheng L, Logar A, et al. Cytokine Expression by human peripheral blood dendritic cells stimulated in vitro with HIV-1 and herpes simplex virus. J Immunol 1996, 157:4028-4036.
18. Grouard C, Clark E. Role of dendritic and follicular dendritic cells in HIV infection and pathogenesis. Curr Opin Immunol 1997, 9:563-567.
19. Chun T, Engel D, Mizell S, Ehler L, Fauci A. Induction of HIV-1 replication in latently infected CD4+ T cells using a combination of cytokines. J Exp Med 1998, 188:83-91.
20. Weissman D, Daucher J, Barker T, et al. Cytokine Regulation of HIV replication induced by dendritic cell-CD4-positive T cell interactions. Aids Res Hum Retroviruses 1996, 12:759-767.
21. Fauci A, Pantaleo G, Stanley S, Weissman D. Immunopathogenic mechanisms of HIV infection. Ann Intern Med 1996, 124:654-663.
22. Graziosi C, Pantaleo C, Gantt KR, et al. Lack of evidence for the dichotomy of TH1 and TH2 predominance in HIV-infected individuals. Science 1994, 265:248-252.
23. Poli G, Fauci AS. The role of cytokines in the pathogenesis of human immunodeficiency virus infection. In Human Cytokines: Their Role in Disease and Therapy. Edited by Aggarwal BB Puri RK. Cambridge, MA: Blackwell Scientific; 1995:421-449.
24. Sönnerborg A, Ehrnst A, Bergdahl S, et al. HIV isolation from cerebrospinal fluid in relation to neurological symptoms and immunological deficiency. AIDS 1988, 2:89-93.
25. Salazar-Gonzalez J, Martinez-Maza O, Aziz N, et al. Relationship of plasma HIV-RNA levels and levels of TNF-alpha and immune activation products in HIV infection. Clin Immunol Immunopathol 1997, 84:36-45.
26. Godard CM, Chermann J-C. Stimulation of bystander T-cell proliferation by tumor necrosis factor produced by HIV-1 infected macrophages. J Hum Virol 1998, 1:257-266.
27. Jacque J, Mann A, Enslen H, et al. Modulation of HIV-1 infectivity by MARK, a virion-associated kinase. EMBO J 1998, 18:2607-2618.
28. Cohen P, Nakshatri H, Dennis J, et al. CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency. Proc Natl Acad Sci USA 1996, 9:3967-3971.
29. Lee J, Laydon J, McDonnell P, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994, 372:739-746.
30. Sawaya BE, Thatikunta P, Denisova L, et al. Regulation of TNFalpha and TGFbeta-1 gene transcription by HIV-1 Tat in CNS cells. J Neuroimmunol 1998, 87:33-42.
31. Yang X, Gabuzda D. Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway. J Virol 1999, 73:3460-3466.
32. Larrick J, Morhenn V, Chiang Y, Shi T. Activated Langerhans cells release tumor necrosis factor. J Leukoc Biol 1989, 45:429-433.
33. Ulevitch R, Tobias P. Recognition of endotoxin by cells leading to transmembrane signaling. Curr Opin Immunol 1994, 6:125-130.
34. Ulevitch R, Tobias P. Receptor-dependent mechanism of cell stimulation by bacterial mechanism. Annu Rev Immunol 1995, 13:437-457.
35. Zhang F, Kirschning C, Mancinelli R, et al. Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J Biol Chem 1999, 274:7611-7614.
36. Canque B, Rosenzwajg M, Camus S, et al. The effect of in vitro human immunodeficiency virus infection on dendritic-cell differentiation and function. Blood 1996, 88:4215-4228.