Role of dendritic and follicular dendritic cells in HIV infection and pathogenesis

Current Opinion in Immunology

Volumn 9, Issue 4, 1997, Pages 563-567

  Grouard, Geraldine ^a   Clark, Edward A ^a  

^a UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN;

DENDRITIC CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOID TISSUE; OVARY FOLLICLE CELL; REVIEW; T LYMPHOCYTE; VIRUS PATHOGENESIS;

EID: 0030864869     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(97)80111-2     Document Type: Article

References (41)

1. Kelsoe G. Life and death in germinal centers (redux). Immunity. 4:1996;107-111.
2. Liu YJ, Grouard G, de Bouteiller O, Banchereau J. Follicular dendritic cells and germinal centers. Int Rev Cytol. 166:1996;139-179.
3. Banchereau J, Schmitt D. Dendritic Cells in Fundamental and Clinical Immunology. 1995;Plenum Press, New York.
4. Steinman RM. The dendritic cell in clinical immunology: the AIDS example. J Lab Clin Med. 128:1996;531-535.
5. Sallusto F, Cella M, Danieli C, Lanzavecchia A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med. 182:1995;389-400.
6. Cella M, Scheidegger D, Palmer-Lehmann K, Lane P, Lanzavecchia A, Alber G. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J Exp Med. 184:1996;747-752.
7. Chvatchko Y, Kosco-Vilbois MH, Herren S, Lefort J, Bonnefoy J-Y. Germinal center formation and local immunoglobulin E (IgE) production in the lung after an airway antigenic challenge. J Exp Med. 184:1996;2353-2360.
8. Clark EA. The interdependence of lymphocyte, stromal cell, and follicular dendritic cell maturation. Adv Exp Med Biol. 378:1995;285-288.
9. Liu YJ, Xu J, de Bouteiller O, Parham CL, Grouard G, Djossou O, de Saint Vis B, Lebecque S, Banchereau J, Moore KW. Follicular dendritic cells specifically express the long CR2/CD21 isoform. J Exp Med. 185:1997;165-170.
10. Pantaleo G, Graziosi C, Demarest JF, Butini L, Montroni M, Fox CH, Orenstein JM, Kotler DP, Fauci AS. HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature. 362:1993;355-358.
11. Embretson J, Zupancic M, Ribas JL, Burke A, Racz P, Tenner Racz K, Haase AT. Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature. 362:1993;359-362.
12. Fauci AS. Host factors and the pathogenesis of HIV-induced disease. Nature. 384:1996;529-534.
13. Clark EA. HIV: dendritic cells as embers for the infectious fire. Curr Biol. 6:1996;655-657.
14. Zambruno G, Giannetti A, Bertazzoni U, Girolomoni G. Langerhans cells and HIV infection. Immunol Today. 16:1995;520-524.
15. Frankel SS, Thompson BM, Burke AP, Mannan P, Thompson LDR, Abbondanzo SL, Melson AM, Pope M, Steinman RM. HIV-1 replication in syncytia, derived from dendritic cells, at the mucosal surface of the adenoid. of outstanding interest Science. 272:1996;115-117 Demonstration that HIV-1 can be found in vivo in the mucosal tissue from asymptomatic HIV infected individuals. The mucosal tissue was shown to contain syncytia, apparently composed of DCs and T cells, and to be infected with HIV-1.
16. Spira AI, Marx PA, Patterson BK, Mahoney J, Koup RA, Wolinsky SM, Ho DD. Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques. of special interest J Exp Med. 183:1996;215-225 Evaluation of cells expressing SIV in the vaginal mucosa early after intravaginal infection of macaques with SIV. The first cellular targets for SIV are found to be in the lamina propria of the cervicovaginal mucosa and are likely to be DCs.
17. Cameron PU, Lowe MG, Sotzik F, Coughlan AF, Crowe SM, Shortman K. The interaction of macrophage and non-macrophage tropic isolates of HIV-1 with thymic and tonsillar dendritic cells in vitro. of special interest J Exp Med. 183:1996;1851-1856 Reports that both tonsillar and thymic DCs can be infected directly with a monocytotropic HIV-1 isolate but not with a T cell tropic isolate; however, the uninfected DCs could carry and promote infection of T cells by the T cell tropic isolate.
18. Sotzik F, Rosenberg Y, Boyd AW, Honeyman M, Metcalf D, Scollay R, Wu L, Shortman K. Assessment of CD4 expression by early T precursor cells and by dendritic cells in the human thymus. J Immunol. 152:1994;3370-3377.
19. O'Doherty U, Steinman RM, Peng M, Cameron PU, Gezelter S, Kopeloff I, Swiggard WJ, Pope M, Bhardwaj N. Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium. J Exp Med. 178:1993;1067-1076.
20. Granelli-Piperno A, Moser B, Pope M, Chen D, Wei Y, Isdell F, O'Doherty U, Paxton W, Koup R, Mojsov S, Bhardwaj N, et al. Efficient interaction HIV-1 with purified dendritic cells via multiple chemokine coreceptors. of outstanding interest J Exp Med. 184:1996;2433-2438 Investigation of HIV-1 cDNA synthesis and expression in DCs revealed that both monocytotropic and T cell tropic HIV isolates efficiently enter DCs and that HIV-1 actually begins reverse transcription much more efficiently in DCs than in T cells. DCs express both CCR5 and CXCR4 co-receptors for HIV-1.
21. + T cells. Science. 257:1992;383-387.
22. Pinchuk LM, Polacino PS, Agy MB, Klaus SJ, Clark EA. The role of CD40 and CD80 accessory cell molecules in dendritic cell-dependent HIV-1 infection. Immunity. 1:1994;317-325.
23. Pope M, Betjes MG, Romani N, Hirmand H, Cameron PU, Hoffman L, Gezelter S, Schuler G, Steinman RM. Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1. Cell. 78:1994;389-398.
24. Weiss RA. HIV receptors and the pathogenesis of AIDS. Science. 272:1996;1885-1886.
25. Liu R, Paxton WA, Choe S, Ceradini D, Martin SR, Horuk R, MacDonald ME, Stuhlmann H, Koup RA, Landau NR. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. of special interest Cell. 86:1996;367-377 Reports that some individuals have mutations in the gene encoding the HIV-1 co-receptor CCR-5 which protect them from infection by HIV-1, even after multiple potential exposures.
26. + T cells requires a cyclosporin A-sensitive pathway. J Immunol. 158:1997;512-517.
27. Kozak SL, Platt EJ, Madani N, Ferro FE Jr, Peden K, Kabat D. CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1. J Virol. 71:1997;873-882.
28. Grouard G, Durand I, Filgueira L, Banchereau J, Liu YJ. Dendritic cells capable of stimulating T cells in germinal centres. of special interest Nature. 384:1996;364-367 Identification of a new subset of DCs in germinal centers, which are distinct from FDCs, and are probable candidates for regulators of immunological memory.
29. Caux C, Banchereau J. In vitro regulation of dendritic cell development and function. Whetton T, Gordon G. Blood Cell Biochemistry. 1996;263-301 Plenum Press, London.
30. Canque B, Rosenzwajg M, Camus S, Yagello M, Bonnet ML, Guigon M, Gluckman JC. The effect of in vitro human immunodeficiency virus infection on dendritic-cell differentiation and function. Blood. 88:1996;4215-4228.
31. Charbonnier AS, Verrier B, Jacquet C, Massacrier C, Fiers MM, Mallet F, Dezutter-Dambuyant C, Schmitt D. In vitro HIV1 infection of CD34+ progenitor-derived dendritic/Langerhans cells at different stages of their differentiation in the presence of GM-CSF/TNF alpha. Res Virol. 147:1996;89-95.
32. Fox CH, Cottler-Fox M. The pathobiology of HIV infection. Immunol Today. 13:1992;353-356.
33. Schmitz J, van-Luzen J, Tenner-Racz K, Grossschupff G, Racz P, Schmitz H, Dietrich M, Hufert FT. Follicular dendritic cells retain HIV-1 particles on their plasma membrane, but are not productively infected in asymptomatic patients with follicular hyperplasia. J Immunol. 153:1994;1352-1359.
34. Reinhart TA, Rogan MJ, Viglianti GA, Rausch DM, Eiden LE, Haase AT. A new approach to investigating the relationship between productive infection and cytopathicity in vivo. of outstanding interest Nat Med. 3:1997;218-221 A sensitive in situ hybridization method was used to detect unspliced and spliced SIV viral mRNAs in lymphoid tissues from SIV-infected animals. Spliced RNAs were not detected in FDCs, so FDCs are not productively infected.
35. Haase AT, Henry K, Zupancic M, Sedgewick G, Faust RA, Melroe H, Cavert W, Gebhard K, Staskus K, Zhang ZQ, et al. Quantitative image analysis of HIV-1 infection in lymphoid tissue. of outstanding interest Science. 274:1996;985-989 A careful analysis correlating the amount of circulating HIV in the blood with the amount of HIV detected associated with peripheral lymphoid FDCs.
36. Heath SL, Tew GJ, Tew JG, Szakal AK, Burton GF. Follicular dendritic cells and human immunodeficiency virus infectivity. Nature. 377:1995;740-744.
37. Kim HS, Zhang X, Choi YS. Activation and proliferation of follicular dendritic cell-like cells by activated T lymphocytes. J Immunol. 153:1994;2951-2961.
38. Pantaleo G, Fauci AS. New concepts in the immunopathogenesis of HIV infection. Annu Rev Immunol. 13:1995;487-512.
39. Kapasi ZF, Burton GF, Schultz LD, Tew J, Szakal AK. Induction of functional follicular dendritic cell development in severe combined immunodeficiency mice. J Immunol. 150:1993;2648-2658.
40. Yoshida K, Kaji M, Takahashi T, Van Den Berg TK, Dijkstra CD. Host origin of follicular dendritic cells induced in the spleen of Scid mice after transfer of allogeneic lymphocytes. Immunology. 84:1995;117-126.
41. Grouard G, Rissoan MC, Filgueira L, Durand I, Banchereau J, Liu YJ. The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand. J Exp Med. 185:1997;1101-1111.