메뉴 건너뛰기




Volumn 6, Issue 3, 2004, Pages 248-257

Inhibition of tumor growth and angiogenesis by soluble EphB4

Author keywords

Angiogenesis; Endothelial cells; EphB4; EphrinB2; Tumor

Indexed keywords

EPHRIN; EPHRIN B2; EPHRIN B4; EPHRIN RECEPTOR; LIGAND; UNCLASSIFIED DRUG;

EID: 2442706421     PISSN: 15228002     EISSN: None     Source Type: Journal    
DOI: 10.1593/neo.3457     Document Type: Article
Times cited : (120)

References (42)
  • 1
    • 0035313727 scopus 로고    scopus 로고
    • Excitatory Eph receptors and adhesive ephrin ligands
    • Klein R (2001). Excitatory Eph receptors and adhesive ephrin ligands. Curr Opin Cell Biol 13, 196-203.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 196-203
    • Klein, R.1
  • 2
    • 0036303033 scopus 로고    scopus 로고
    • Mechanisms and functions of Eph and ephrin signalling
    • Kullander K and Klein R (2002). Mechanisms and functions of Eph and ephrin signalling. Nat Rev Mol Cell Biol 3, 475-486.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 475-486
    • Kullander, K.1    Klein, R.2
  • 3
    • 0035875044 scopus 로고    scopus 로고
    • Signaling downstream of Eph receptors and ephrin ligands
    • Schmucker D and Zipursky SL (2001). Signaling downstream of Eph receptors and ephrin ligands. Cell 105, 701-704.
    • (2001) Cell , vol.105 , pp. 701-704
    • Schmucker, D.1    Zipursky, S.L.2
  • 4
    • 0030891962 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of transmembrane ligands for Eph receptors
    • Bruckner K, Pasquale EB, and Klein R (1997). Tyrosine phosphorylation of transmembrane ligands for Eph receptors. Science 275, 1640-1643.
    • (1997) Science , vol.275 , pp. 1640-1643
    • Bruckner, K.1    Pasquale, E.B.2    Klein, R.3
  • 5
    • 0029851690 scopus 로고    scopus 로고
    • Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands
    • Holland SJ, Gale NW, Mbamalu G, Yancopoulos GD, Henkemeyer M, and Pawson T (1996). Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands. Nature 383, 722-725.
    • (1996) Nature , vol.383 , pp. 722-725
    • Holland, S.J.1    Gale, N.W.2    Mbamalu, G.3    Yancopoulos, G.D.4    Henkemeyer, M.5    Pawson, T.6
  • 6
    • 0030929986 scopus 로고    scopus 로고
    • The Eph receptor family: Axonal guidance by contact repulsion
    • Orioli D and Klein R (1997). The Eph receptor family: axonal guidance by contact repulsion. Trends Genet 13, 354-359.
    • (1997) Trends Genet , vol.13 , pp. 354-359
    • Orioli, D.1    Klein, R.2
  • 7
    • 0032577446 scopus 로고    scopus 로고
    • Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
    • Wang HU, Chen ZF, and Anderson DJ (1998). Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93, 741-753.
    • (1998) Cell , vol.93 , pp. 741-753
    • Wang, H.U.1    Chen, Z.F.2    Anderson, D.J.3
  • 8
    • 0033082959 scopus 로고    scopus 로고
    • Roles of ephrinB ligands and EphB receptors in cardiovascular development: Demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis
    • Adams RH, Wilkinson GA, Weiss C, Diella F, Gale NW, Deutsch U, Risau W, and Klein R (1999). Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev 13, 295-306.
    • (1999) Genes Dev , vol.13 , pp. 295-306
    • Adams, R.H.1    Wilkinson, G.A.2    Weiss, C.3    Diella, F.4    Gale, N.W.5    Deutsch, U.6    Risau, W.7    Klein, R.8
  • 9
    • 0036445885 scopus 로고    scopus 로고
    • Vascular patterning by Eph receptor tyrosine kinases and ephrins
    • Adams RH (2002). Vascular patterning by Eph receptor tyrosine kinases and ephrins. Semin Cell Dev Biol 13, 55-60.
    • (2002) Semin Cell Dev Biol , vol.13 , pp. 55-60
    • Adams, R.H.1
  • 10
    • 0035865227 scopus 로고    scopus 로고
    • Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth muscle cells
    • Gale NW, Baluk P, Pan L, Kwan M, Holash J, DeChiara TM, McDonald DM, and Yancopoulos GD (2001). Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth muscle cells. Dev Biol 230, 151-160.
    • (2001) Dev Biol , vol.230 , pp. 151-160
    • Gale, N.W.1    Baluk, P.2    Pan, L.3    Kwan, M.4    Holash, J.5    DeChiara, T.M.6    McDonald, D.M.7    Yancopoulos, G.D.8
  • 11
    • 0035865049 scopus 로고    scopus 로고
    • Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization
    • Shin D, Garcia-Cardena G, Hayashi SI, Gerety S, Asahara T, Stavrakis G, Isner J, Folkman J, Gimbrone MA, and Anderson DJ (2001). Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization. Dev Biol 230, 139-150.
    • (2001) Dev Biol , vol.230 , pp. 139-150
    • Shin, D.1    Garcia-Cardena, G.2    Hayashi, S.I.3    Gerety, S.4    Asahara, T.5    Stavrakis, G.6    Isner, J.7    Folkman, J.8    Gimbrone, M.A.9    Anderson, D.J.10
  • 12
    • 0035846911 scopus 로고    scopus 로고
    • The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration
    • Adams RH, Diella F, Hennig S, Helmbacher F, Deutsch U, and Klein R (2001). The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration. Cell 104, 57-69.
    • (2001) Cell , vol.104 , pp. 57-69
    • Adams, R.H.1    Diella, F.2    Hennig, S.3    Helmbacher, F.4    Deutsch, U.5    Klein, R.6
  • 13
    • 0038497941 scopus 로고    scopus 로고
    • Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells
    • Füller T, Korff T, Kilian A, Dandekar G, and Augustin HG (2003). Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells. J Cell Sci 116, 2461-2470.
    • (2003) J Cell Sci , vol.116 , pp. 2461-2470
    • Füller, T.1    Korff, T.2    Kilian, A.3    Dandekar, G.4    Augustin, H.G.5
  • 15
    • 0034693857 scopus 로고    scopus 로고
    • Eph receptors and ephrin ligands: Embryogenesis to tumorigenesis
    • Dodelet VC and Pasquale EB (2000). Eph receptors and ephrin ligands: embryogenesis to tumorigenesis. Oncogene 19, 5614-5619.
    • (2000) Oncogene , vol.19 , pp. 5614-5619
    • Dodelet, V.C.1    Pasquale, E.B.2
  • 17
    • 0034619758 scopus 로고    scopus 로고
    • The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization
    • Ogawa K, Pasqualini R, Lindberg RA, Kain R, Freeman AL, and Pasquale EB (2000). The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization. Oncogene 19, 6043-6052.
    • (2000) Oncogene , vol.19 , pp. 6043-6052
    • Ogawa, K.1    Pasqualini, R.2    Lindberg, R.A.3    Kain, R.4    Freeman, A.L.5    Pasquale, E.B.6
  • 20
    • 0037093097 scopus 로고    scopus 로고
    • Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior
    • Carles-Kinch K, Kilpatrick KE, Stewart JC, and Kinch MS (2002). Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior. Cancer Res 62, 2840-2847.
    • (2002) Cancer Res , vol.62 , pp. 2840-2847
    • Carles-Kinch, K.1    Kilpatrick, K.E.2    Stewart, J.C.3    Kinch, M.S.4
  • 21
    • 0036785161 scopus 로고    scopus 로고
    • Diverse roles for the Eph family of receptor tyrosine kinases in carcinogenesis
    • Nakamoto M and Bergemann AD (2002). Diverse roles for the Eph family of receptor tyrosine kinases in carcinogenesis. Microsc Res Tech 59, 58-67.
    • (2002) Microsc Res Tech , vol.59 , pp. 58-67
    • Nakamoto, M.1    Bergemann, A.D.2
  • 22
    • 0242688270 scopus 로고    scopus 로고
    • EphB4/ephrinB2 expression by malignant mesothelioma as a potential therapeutic target
    • Chen E, Xia G, Kundra A, Smith DL, Masood R, and Gill P (2003). EphB4/ephrinB2 expression by malignant mesothelioma as a potential therapeutic target. Proc Am Assoc Cancer Res 44, 475.
    • (2003) Proc Am Assoc Cancer Res , vol.44 , pp. 475
    • Chen, E.1    Xia, G.2    Kundra, A.3    Smith, D.L.4    Masood, R.5    Gill, P.6
  • 24
    • 0031946730 scopus 로고    scopus 로고
    • Overexpression of Lerk-5/Eplg5 messenger RNA: A novel marker for increased tumorigenicity and metastatic potential in human malignant melanomas
    • Vogt T, Stolz W, Welsh J, Jung B, Kerbel RS, Kobayashi H, Landthaler M, and McClelland M (1998). Overexpression of Lerk-5/Eplg5 messenger RNA: a novel marker for increased tumorigenicity and metastatic potential in human malignant melanomas. Clin Cancer Res 4, 791-797.
    • (1998) Clin Cancer Res , vol.4 , pp. 791-797
    • Vogt, T.1    Stolz, W.2    Welsh, J.3    Jung, B.4    Kerbel, R.S.5    Kobayashi, H.6    Landthaler, M.7    McClelland, M.8
  • 25
    • 0035345024 scopus 로고    scopus 로고
    • Expression of receptor tyrosine kinase EphB4 and its ligand ephrin-B2 is associated with malignant potential in endometrial cancer
    • Takai N, Miyazaki T, Fujisawa K, Nasu K, and Miyakawa I (2001). Expression of receptor tyrosine kinase EphB4 and its ligand ephrin-B2 is associated with malignant potential in endometrial cancer. Oncol Rep 8, 567-573.
    • (2001) Oncol Rep , vol.8 , pp. 567-573
    • Takai, N.1    Miyazaki, T.2    Fujisawa, K.3    Nasu, K.4    Miyakawa, I.5
  • 26
    • 0031786126 scopus 로고    scopus 로고
    • Cell-type specific and estrogen dependent expression of the receptor tyrosine kinase EphB4 and its ligand ephrinB2 during mammary gland morphogenesis
    • Nikolova Z, Djonov V, Zuercher G, Andres AC, and Ziemiecki A (1998). Cell-type specific and estrogen dependent expression of the receptor tyrosine kinase EphB4 and its ligand ephrinB2 during mammary gland morphogenesis. J Cell Sci 111, 2741-2751.
    • (1998) J Cell Sci , vol.111 , pp. 2741-2751
    • Nikolova, Z.1    Djonov, V.2    Zuercher, G.3    Andres, A.C.4    Ziemiecki, A.5
  • 27
    • 0032979215 scopus 로고    scopus 로고
    • High-level expression of EPHB6, EFNB2, and EFNB3 is associated with low tumor stage and high TrkA expression in human neuroblastomas
    • Tang XX, Evans AE, Zhao H, Cnaan A, London W, Cohn SL, Brodeur GM, and Ikegaki N (1999). High-level expression of EPHB6, EFNB2, and EFNB3 is associated with low tumor stage and high TrkA expression in human neuroblastomas. Clin Cancer Res 5, 1491-1496.
    • (1999) Clin Cancer Res , vol.5 , pp. 1491-1496
    • Tang, X.X.1    Evans, A.E.2    Zhao, H.3    Cnaan, A.4    London, W.5    Cohn, S.L.6    Brodeur, G.M.7    Ikegaki, N.8
  • 29
    • 0037099598 scopus 로고    scopus 로고
    • PTK787/ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging
    • Drevs J, Müller-Driver R, Wittig C, Fuxius S, Esser N, Hugenschmidt H, Konerding MA, Allegrini PR, Wood J, Hennig J, Unger C, and Marme D (2002). PTK787/ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging. Cancer Res 62, 4015-4022.
    • (2002) Cancer Res , vol.62 , pp. 4015-4022
    • Drevs, J.1    Müller-Driver, R.2    Wittig, C.3    Fuxius, S.4    Esser, N.5    Hugenschmidt, H.6    Konerding, M.A.7    Allegrini, P.R.8    Wood, J.9    Hennig, J.10    Unger, C.11    Marme, D.12
  • 30
    • 0033168916 scopus 로고    scopus 로고
    • Two independent mechanisms essential for tumor angiogenesis: Inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway
    • Siemeister G, Schirner M, Weindel K, Reusch P, Menrad A, Marme D, and Martiny-Baron G (1999). Two independent mechanisms essential for tumor angiogenesis: inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway. Cancer Res 59, 3185-3191.
    • (1999) Cancer Res , vol.59 , pp. 3185-3191
    • Siemeister, G.1    Schirner, M.2    Weindel, K.3    Reusch, P.4    Menrad, A.5    Marme, D.6    Martiny-Baron, G.7
  • 31
    • 0032583125 scopus 로고    scopus 로고
    • Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation
    • Korff T and Augustin HG (1998). Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation. J Cell Biol 143, 1341-1352.
    • (1998) J Cell Biol , vol.143 , pp. 1341-1352
    • Korff, T.1    Augustin, H.G.2
  • 32
    • 0032748089 scopus 로고    scopus 로고
    • Tensional forces in fibrillar extracellular matrices control directional capillary sprouting
    • Korff T and Augustin HG (1999). Tensional forces in fibrillar extracellular matrices control directional capillary sprouting. J Cell Sci 112, 3249-3258.
    • (1999) J Cell Sci , vol.112 , pp. 3249-3258
    • Korff, T.1    Augustin, H.G.2
  • 35
    • 0036985699 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: Therapeutic implications
    • Ferrara N (2002). Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications. Semin Oncol 29, 10-14.
    • (2002) Semin Oncol , vol.29 , pp. 10-14
    • Ferrara, N.1
  • 40
    • 0030609013 scopus 로고    scopus 로고
    • Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells
    • Barleon B, Siemeister G, Martiny-Baron G, Weindel K, Herzog C, and Marme D (1997). Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells. Cancer Res 57, 5421-5425.
    • (1997) Cancer Res , vol.57 , pp. 5421-5425
    • Barleon, B.1    Siemeister, G.2    Martiny-Baron, G.3    Weindel, K.4    Herzog, C.5    Marme, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.