Protein engineering as a strategy to avoid formation of amyloid fibrils

Protein Science

Volumn 9, Issue 9, 2000, Pages 1700-1708

  Villegas, Virtudes ^a   Zurdo, Jesús ^b   Filimonov, Vladimir V ^c   Avilés, Francesc X ^a   Dobson, Christopher M ^b   Serrano, Luis ^d  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF GRANADA   (Spain)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

ADA2h domain; Amyloid fibrils; Amyloid formation; Protein engineering; Protein misfolding; Secondary structure propensity

Indexed keywords

AMYLOID; CARBOXYPEPTIDASE A; ENZYME PRECURSOR;

AMYLOIDOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME DENATURATION; ENZYME STABILITY; ENZYME STRUCTURE; GENETIC ENGINEERING; PRIORITY JOURNAL; PROTEIN STRUCTURE;

EID: 0033814617     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.9.9.1700     Document Type: Article

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