메뉴 건너뛰기




Volumn 280, Issue 2 49-2, 2001, Pages

Inhibition of p38 MAPK α/β reduces ischemic injury and does not block protective effects of preconditioning

Author keywords

31P nuclear magnetic resonance; Intracellular pH; Left ventricular developed pressure; Necrosis; SB 202190

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; MITOGEN ACTIVATED PROTEIN KINASE; TRIPHENYLTETRAZOLIUM;

EID: 0035008371     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.2.h499     Document Type: Article
Times cited : (87)

References (39)
  • 1
    • 0033105619 scopus 로고    scopus 로고
    • Phosphorylation state of hsp27 and p38 MAPK during preconditioning and protein phosphatase inhibitor protection of rabbit cardiomyocytes
    • Armstrong SC, Delacey M, and Ganote CE. Phosphorylation state of hsp27 and p38 MAPK during preconditioning and protein phosphatase inhibitor protection of rabbit cardiomyocytes. J Mol Cell Cardiol 31: 555-567, 1999.
    • (1999) J Mol Cell Cardiol , vol.31 , pp. 555-567
    • Armstrong, S.C.1    Delacey, M.2    Ganote, C.E.3
  • 3
    • 0030036727 scopus 로고    scopus 로고
    • Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kmases and c-Jun N-terminal kinases are activated by ischemia/reperfusion
    • Bogoyevitch MA, Gillespie-Brown J, Ketterman AJ, Fuller SJ, Ben-Levy R, Ashworth A, Marshall CJ, and Sugden PH. Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kmases and c-Jun N-terminal kinases are activated by ischemia/reperfusion. Circ Res 79: 162-73, 1996.
    • (1996) Circ Res , vol.79 , pp. 162-173
    • Bogoyevitch, M.A.1    Gillespie-Brown, J.2    Ketterman, A.J.3    Fuller, S.J.4    Ben-Levy, R.5    Ashworth, A.6    Marshall, C.J.7    Sugden, P.H.8
  • 4
    • 0030783156 scopus 로고    scopus 로고
    • The search for physiological substrates of MAP and SAP kinases in mammalian cells
    • Cohen P. The search for physiological substrates of MAP and SAP kinases in mammalian cells. Trends Cell Biol 7: 353-361, 1997.
    • (1997) Trends Cell Biol , vol.7 , pp. 353-361
    • Cohen, P.1
  • 5
    • 0028988138 scopus 로고
    • SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
    • Cuenda A, Rouse J, Doza YN, Meier R, Cohen P, Gallagher TF, Young PR, and Lee JC. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 364: 229-233, 1995.
    • (1995) FEBS Lett , vol.364 , pp. 229-233
    • Cuenda, A.1    Rouse, J.2    Doza, Y.N.3    Meier, R.4    Cohen, P.5    Gallagher, T.F.6    Young, P.R.7    Lee, J.C.8
  • 6
    • 0032479983 scopus 로고    scopus 로고
    • Mitogen-and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB
    • Deak M, Clifton AD, Lucocq LM, and Alessi DR. Mitogen-and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. EMBO J 17: 4426-4441, 1998.
    • (1998) EMBO J , vol.17 , pp. 4426-4441
    • Deak, M.1    Clifton, A.D.2    Lucocq, L.M.3    Alessi, D.R.4
  • 8
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: Downstream AKTion blocks apoptosis
    • Franke TF, Kaplan DR, and Cantley LC. PI3K: downstream AKTion blocks apoptosis. Cell 88: 435-437, 1997.
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 9
    • 0021888348 scopus 로고
    • Effects of anoxic or oxygenated reperfusion in globally ischemic, isovolumic, perfused rat hearts
    • Ganote CE and Humphrey SM. Effects of anoxic or oxygenated reperfusion in globally ischemic, isovolumic, perfused rat hearts. Am J Pathol 120: 129-145, 1985.
    • (1985) Am J Pathol , vol.120 , pp. 129-145
    • Ganote, C.E.1    Humphrey, S.M.2
  • 11
    • 0018631684 scopus 로고
    • Studies of acidosis in the ischaemic heart by phosphorus nuclear magnetic resonance
    • Garlick PB, Radda GK, and Seeley PJ. Studies of acidosis in the ischaemic heart by phosphorus nuclear magnetic resonance. Biochem J 184: 547-554, 1979.
    • (1979) Biochem J , vol.184 , pp. 547-554
    • Garlick, P.B.1    Radda, G.K.2    Seeley, P.J.3
  • 12
    • 0028860586 scopus 로고
    • The activation of distinct mitogen-activated protein kinase cascades is required for the stimulation of 2-deoxyglucose uptake by interleukin-1 and insulin-like growth factor-1 in KB cells
    • Gould GW, Cuenda A, Thomson FJ, and Cohen P. The activation of distinct mitogen-activated protein kinase cascades is required for the stimulation of 2-deoxyglucose uptake by interleukin-1 and insulin-like growth factor-1 in KB cells. Biochem J 311: 735-738, 1995.
    • (1995) Biochem J , vol.311 , pp. 735-738
    • Gould, G.W.1    Cuenda, A.2    Thomson, F.J.3    Cohen, P.4
  • 13
    • 0031056783 scopus 로고    scopus 로고
    • Regulation of actin filament dynamics by p38 MAP kinase-mediated phosphorylation of heat shock protein 27
    • Guay J, Lambert H, Gingras-Breton G, Lavoie JN, Huot J, and Landry J. Regulation of actin filament dynamics by p38 MAP kinase-mediated phosphorylation of heat shock protein 27. J Cell Sci 110: 357-368, 1997.
    • (1997) J Cell Sci , vol.110 , pp. 357-368
    • Guay, J.1    Lambert, H.2    Gingras-Breton, G.3    Lavoie, J.N.4    Huot, J.5    Landry, J.6
  • 15
    • 0030198344 scopus 로고    scopus 로고
    • Protein kinase cascades activated by stress and inflammatory cytokines
    • Kyriakis JM and Avruch J. Protein kinase cascades activated by stress and inflammatory cytokines. Bioessays 18: 567-577, 1996.
    • (1996) Bioessays , vol.18 , pp. 567-577
    • Kyriakis, J.M.1    Avruch, J.2
  • 16
    • 0034629345 scopus 로고    scopus 로고
    • The pyridinyl imidazole inhibitor SB203580 blocks phosphoinositide-dependent protein kinase activity, protein kinase B phosphorylation, and retinoblastoma hyperphosphorylation in interleukin-2stimulated T cells independently of p38 mitogen-activated protein kinase
    • Lali FV, Hunt AE, Turner SJ, and Foxwell BM. The pyridinyl imidazole inhibitor SB203580 blocks phosphoinositide-dependent protein kinase activity, protein kinase B phosphorylation, and retinoblastoma hyperphosphorylation in interleukin-2stimulated T cells independently of p38 mitogen-activated protein kinase. J Biol Chem 275: 7395-7402, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 7395-7402
    • Lali, F.V.1    Hunt, A.E.2    Turner, S.J.3    Foxwell, B.M.4
  • 17
    • 0027166979 scopus 로고
    • Ischemic and hypoxic preconditioning enhances post ischemic recovery of function in rat heart
    • Lasley RD, Anderson GM, and Mentzer RM. Ischemic and hypoxic preconditioning enhances post ischemic recovery of function in rat heart. Cardiovasc Res 27: 565-570, 1993.
    • (1993) Cardiovasc Res , vol.27 , pp. 565-570
    • Lasley, R.D.1    Anderson, G.M.2    Mentzer, R.M.3
  • 19
    • 0026490398 scopus 로고
    • Ischemic preconditioning protects against infarction in rat heart
    • Liu Y and Downey JM. Ischemic preconditioning protects against infarction in rat heart. Am J Physiol Heart Circ Physiol 263: H1107-H1112, 1992.
    • (1992) Am J Physiol Heart Circ Physiol , vol.263
    • Liu, Y.1    Downey, J.M.2
  • 20
    • 0033528695 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion
    • Ma XL, Kumar S, Feng G, Lounden CS, Lopez BL, Christopher TA, Wang C, Lee JC, Feuerstein GZ, and Yue T. Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion. Circulation 99: 1685-1691, 1999.
    • (1999) Circulation , vol.99 , pp. 1685-1691
    • Ma, X.L.1    Kumar, S.2    Feng, G.3    Lounden, C.S.4    Lopez, B.L.5    Christopher, T.A.6    Wang, C.7    Lee, J.C.8    Feuerstein, G.Z.9    Yue, T.10
  • 21
    • 0033525760 scopus 로고    scopus 로고
    • An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia
    • Mackay K and Mochly-Rosen D. An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia. J Biol Chem 274: 6272-6279, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 6272-6279
    • Mackay, K.1    Mochly-Rosen, D.2
  • 22
    • 0030569291 scopus 로고    scopus 로고
    • Ischemic preconditioning triggers the activation of MAP kinases and MAPKAP kinase 2 in rat hearts
    • Maulik N, Watanabe M, Zu YL, Huang CK, Cordis GA, Schley JA, and Das DK. Ischemic preconditioning triggers the activation of MAP kinases and MAPKAP kinase 2 in rat hearts. FEBS Lett 396: 233-237, 1996.
    • (1996) FEBS Lett , vol.396 , pp. 233-237
    • Maulik, N.1    Watanabe, M.2    Zu, Y.L.3    Huang, C.K.4    Cordis, G.A.5    Schley, J.A.6    Das, D.K.7
  • 23
    • 0022970945 scopus 로고
    • Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
    • Murry CE, Jennings RB, and Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74: 1124-1136, 1986.
    • (1986) Circulation , vol.74 , pp. 1124-1136
    • Murry, C.E.1    Jennings, R.B.2    Reimer, K.A.3
  • 24
    • 0025216421 scopus 로고
    • Ischemic preconditioning slows energy metabolism and delays ultrastructural damage during a sustained ischemic episode
    • Murry CE, Richard VJ, Reimer KA, and Jennings RB. Ischemic preconditioning slows energy metabolism and delays ultrastructural damage during a sustained ischemic episode. Circ Res 66: 913-931, 1990.
    • (1990) Circ Res , vol.66 , pp. 913-931
    • Murry, C.E.1    Richard, V.J.2    Reimer, K.A.3    Jennings, R.B.4
  • 25
    • 0033960626 scopus 로고    scopus 로고
    • Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: Evidence for involvement of p38 MAPK
    • Nakano A, Baines CP, Kim SO, Pelech SL, Downey JM, Cohen MV, and Critz SD. Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: evidence for involvement of p38 MAPK. Circ Res 86: 144-151, 2000.
    • (2000) Circ Res , vol.86 , pp. 144-151
    • Nakano, A.1    Baines, C.P.2    Kim, S.O.3    Pelech, S.L.4    Downey, J.M.5    Cohen, M.V.6    Critz, S.D.7
  • 26
    • 0034640266 scopus 로고    scopus 로고
    • Role of p38 mitogen-activated protein kinases in preconditioning: A detrimental factor or a protective kinase?
    • Ping P and Murphy E. Role of p38 mitogen-activated protein kinases in preconditioning: a detrimental factor or a protective kinase? Circ Res 86: 921-922, 2000.
    • (2000) Circ Res , vol.86 , pp. 921-922
    • Ping, P.1    Murphy, E.2
  • 28
    • 0024820708 scopus 로고
    • Effect of a critical coronary stenosis on myocardial neutrophil accumulation during ischemia and early reperfusion in dogs
    • Richard VJ, Brooks SE, Jennings RB, and Reimer KA. Effect of a critical coronary stenosis on myocardial neutrophil accumulation during ischemia and early reperfusion in dogs. Circulation 80: 1805-1815, 1989.
    • (1989) Circulation , vol.80 , pp. 1805-1815
    • Richard, V.J.1    Brooks, S.E.2    Jennings, R.B.3    Reimer, K.A.4
  • 29
    • 6644226740 scopus 로고    scopus 로고
    • Inhibition of P38 alpha activation may underlay protection in surrogate model of ischemic preconditioning
    • Saurin AT, Heads RJ, Foley C, Wang Y, and Marber MS. Inhibition of P38 alpha activation may underlay protection in surrogate model of ischemic preconditioning. Circulation 100: 1-492, 1999.
    • (1999) Circulation , vol.100 , pp. 1-492
    • Saurin, A.T.1    Heads, R.J.2    Foley, C.3    Wang, Y.4    Marber, M.S.5
  • 31
    • 0032563677 scopus 로고    scopus 로고
    • "Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium
    • Sugden PH and Clerk A. "Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium. Circ Res 83: 345-352, 1998.
    • (1998) Circ Res , vol.83 , pp. 345-352
    • Sugden, P.H.1    Clerk, A.2
  • 32
    • 0033537853 scopus 로고    scopus 로고
    • An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes
    • Sweeney G, Somwar R, Ramlal T, Volchuk A, Ueyama A, and Klip A. An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes. J Biol Chem 274: 10071-10078, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 10071-10078
    • Sweeney, G.1    Somwar, R.2    Ramlal, T.3    Volchuk, A.4    Ueyama, A.5    Klip, A.6
  • 33
    • 0034697132 scopus 로고    scopus 로고
    • Preconditioning enhanced glucose uptake is mediated by p38 MAP kinase not by phosphatidylinositol 3-kinase
    • Tong H, Chen W, London RE, Murphy E, and Steenbergen C. Preconditioning enhanced glucose uptake is mediated by p38 MAP kinase not by phosphatidylinositol 3-kinase. J Biol Chem 275: 11981-11986, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 11981-11986
    • Tong, H.1    Chen, W.2    London, R.E.3    Murphy, E.4    Steenbergen, C.5
  • 34
    • 0022380879 scopus 로고
    • Triphenyltetrazolium staining of irreversible ischemic injury following coronary artery occlusion in rats
    • Vivaldi MT, Kloner RA, and Schoen FJ. Triphenyltetrazolium staining of irreversible ischemic injury following coronary artery occlusion in rats. Am J Pathol 121: 522-530, 1985.
    • (1985) Am J Pathol , vol.121 , pp. 522-530
    • Vivaldi, M.T.1    Kloner, R.A.2    Schoen, F.J.3
  • 35
    • 0029806856 scopus 로고    scopus 로고
    • 2 are abrogated by an inhibitor of the p38 mitogen-activated protein kinase cascade in human neutrophils
    • 2 are abrogated by an inhibitor of the p38 mitogen-activated protein kinase cascade in human neutrophils. Biochem J 319: 17-20, 1996.
    • (1996) Biochem J , vol.319 , pp. 17-20
    • Waterman, W.H.1    Molski, T.F.2    Huang, C.K.3    Adams, J.L.4    Sha'afi, R.I.5
  • 36
    • 0031239584 scopus 로고    scopus 로고
    • Phoshorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart
    • Weinbrenner C, Liu GS, Cohen MV, and Downey JM. Phoshorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart. J Cell Molec Cardiol 29: 2383-2391, 1997.
    • (1997) J Cell Molec Cardiol , vol.29 , pp. 2383-2391
    • Weinbrenner, C.1    Liu, G.S.2    Cohen, M.V.3    Downey, J.M.4
  • 37
    • 0029793913 scopus 로고    scopus 로고
    • Attenuated glycogenolysis reduces glycolytic catabolite accumulation during ischemia in preconditioned rat hearts
    • Weiss RG, de Albuquerque CP, Vandegaer K, Chacko VP, and Gerstenblith G. Attenuated glycogenolysis reduces glycolytic catabolite accumulation during ischemia in preconditioned rat hearts. Circ Res 79: 435-446, 1996.
    • (1996) Circ Res , vol.79 , pp. 435-446
    • Weiss, R.G.1    De Albuquerque, C.P.2    Vandegaer, K.3    Chacko, V.P.4    Gerstenblith, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.