2-Methoxyestradiol induces apoptosis in Ewing sarcoma cells through mitochondrial hydrogen peroxide production

Oncogene

Volumn 22, Issue 17, 2003, Pages 2558-2567

  Djavaheri Mergny, Mojgan ^a   Wietzerbin, Juana ^a   Besançon, Françoise ^a  

^a INSERM   (France)

Author keywords

2 Methoxyestradiol; Apoptosis; Ewing tumor; Mitochondria; Reactive oxygen species

Indexed keywords

2 METHOXYESTRADIOL; ALPHA TOCOPHEROL; CASPASE 9; CYTOCHROME C; EBSELEN; HYDROGEN PEROXIDE; PROTEIN P53; ROTENONE; STRESS ACTIVATED PROTEIN KINASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL DESTRUCTION; CANCER SURVIVAL; CELL DEATH; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME RELEASE; EWING SARCOMA; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; OXIDATION; PRIORITY JOURNAL; REDUCTION; SURVIVAL RATE;

ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; CASPASES; CELL DIVISION; ESTRADIOL; HUMANS; HYDROGEN PEROXIDE; MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, TUMOR NECROSIS FACTOR; SARCOMA, EWING'S; TUMOR CELLS, CULTURED;

EID: 0038531029     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206356     Document Type: Article

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