Nitric oxide suppresses apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions

International Journal of Cancer

Volumn 106, Issue 5, 2003, Pages 666-675

  Wenzel, Uwe ^a,b   Kuntz, Sabine ^a   De Sousa, Ulrike Jambor ^a   Daniel, Hannelore ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b Molecular Nutrition Unit   (Germany)

Author keywords

Cytochrome c release; Mitochondrial apoptosis pathway; MRNA level; NO scavenging; Protein level

Indexed keywords

CAMPTOTHECIN; CASPASE 3; CYCLIN B; CYCLIN E; CYCLOOXYGENASE 2; CYTOCHROME C; FLAVONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MYC PROTEIN; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PEROXYNITRITE; PROTEIN BAX; PROTEIN BCL X; PROTEIN P21; PROTEIN P53; SCAVENGER; SUPEROXIDE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN HT29; COLON CARCINOMA; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

APOPTOSIS; BCL-X PROTEIN; CAMPTOTHECIN; CASPASE 3; CASPASES; COLONIC NEOPLASMS; CYTOCHROME C GROUP; DNA PRIMERS; DOWN-REGULATION; ENZYME ACTIVATION; FREE RADICAL SCAVENGERS; HT29 CELLS; HUMANS; IMMUNOBLOTTING; MEMBRANE POTENTIALS; MITOCHONDRIA; MUTATION; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROPRUSSIDE; PENICILLAMINE; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; SUPEROXIDES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0042524358     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.11294     Document Type: Article

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