-
1
-
-
0035749803
-
The promise of retinoids to fight against cancer
-
Altucci L., Gronemeyer H. The promise of retinoids to fight against cancer. Nature Rev Cancer. 1:2001;181-193
-
(2001)
Nature Rev Cancer
, vol.1
, pp. 181-193
-
-
Altucci, L.1
Gronemeyer, H.2
-
2
-
-
0022547592
-
Hepatitis virus DNA integration in a sequence homologous to v-erbA and steroid receptors genes in a hepatocellular carcinoma
-
Dejean A., Bougueleret L., Grzeschick K., Tiollais P. Hepatitis virus DNA integration in a sequence homologous to v-erbA and steroid receptors genes in a hepatocellular carcinoma. Nature. 322:1986;70-72
-
(1986)
Nature
, vol.322
, pp. 70-72
-
-
Dejean, A.1
Bougueleret, L.2
Grzeschick, K.3
Tiollais, P.4
-
3
-
-
0025098239
-
Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene
-
de Thé H., Vivanco-Ruiz MdM., Tiollais P., Stunnenberg H., Dejean A. Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene. Nature. 343:1990;177-180
-
(1990)
Nature
, vol.343
, pp. 177-180
-
-
De Thé, H.1
Vivanco-Ruiz, MdM.2
Tiollais, P.3
Stunnenberg, H.4
Dejean, A.5
-
4
-
-
0028967616
-
R.A.R. specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation
-
Chen J.-Y., Penco S., Ostrowski J., et al. R.A.R. specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation. EMBO J. 14:1995;1187-1197
-
(1995)
EMBO J.
, vol.14
, pp. 1187-1197
-
-
Chen, J.-Y.1
Penco, S.2
Ostrowski, J.3
-
5
-
-
0028999532
-
All-trans retinoic acid as a differentiating agent in the treatment of acute promyelocytic leukemia
-
Degos L., Dombret H., Chomienne C., et al. All-trans retinoic acid as a differentiating agent in the treatment of acute promyelocytic leukemia. Blood. 85:1995;2643-2653
-
(1995)
Blood
, vol.85
, pp. 2643-2653
-
-
Degos, L.1
Dombret, H.2
Chomienne, C.3
-
6
-
-
0033561797
-
Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia
-
Melnick A., Licht J.D. Deconstructing a disease. RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia Blood. 93:1999;3167-3215
-
(1999)
Blood
, vol.93
, pp. 3167-3215
-
-
Melnick, A.1
Licht, J.D.2
-
7
-
-
0030615230
-
A PML RAR alpha transgene initiates murine acute promyelocytic leukemia
-
Brown D., Kogan S., Lagasse E., et al. A PML RAR alpha transgene initiates murine acute promyelocytic leukemia. Proc. Natl. Acad. Sci. USA. 94:1997;2551-2556
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2551-2556
-
-
Brown, D.1
Kogan, S.2
Lagasse, E.3
-
8
-
-
0023752982
-
Use of all trans retinoic acid in the treatment of acute promyelocytic leukaemia
-
Huang M., Ye Y., Chen R., et al. Use of all trans retinoic acid in the treatment of acute promyelocytic leukaemia. Blood. 72:1988;567-572
-
(1988)
Blood
, vol.72
, pp. 567-572
-
-
Huang, M.1
Ye, Y.2
Chen, R.3
-
10
-
-
0031561478
-
Retinoic acid and arsenic: Towards oncogene targeted treatments of acute promyelocytic leukaemia
-
Quignon F., Chen Z., de Thé H. Retinoic acid and arsenic. towards oncogene targeted treatments of acute promyelocytic leukaemia Biochim. Biophys. Acta. 1333:1997;M53-M61
-
(1997)
Biochim. Biophys. Acta
, vol.1333
-
-
Quignon, F.1
Chen, Z.2
De Thé, H.3
-
11
-
-
0035969111
-
Pathways of retinoic acid- or arsenic trioxide-induced PML/RARalpha catabolism, role of oncogene degradation in disease remission
-
Zhu J., Lallemand-Breitenbach V., de The H. Pathways of retinoic acid- or arsenic trioxide-induced PML/RARalpha catabolism, role of oncogene degradation in disease remission. Oncogene. 20:2001;7257-7265
-
(2001)
Oncogene
, vol.20
, pp. 7257-7265
-
-
Zhu, J.1
Lallemand-Breitenbach, V.2
De The, H.3
-
12
-
-
0033638969
-
Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation
-
Minucci S., Maccarana M., Cioce M., et al. Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation. Mol. Cell. 5:2000;811-820
-
(2000)
Mol. Cell
, vol.5
, pp. 811-820
-
-
Minucci, S.1
MacCarana, M.2
Cioce, M.3
-
13
-
-
0032546017
-
Role of the histone deacetylase complex in acute promyelocytic leukaemia
-
Lin R.J., Nagy L., Inoue S., Shao W.L., Miller W.H., Evans R.M. Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature. 391:1998;811-814
-
(1998)
Nature
, vol.391
, pp. 811-814
-
-
Lin, R.J.1
Nagy, L.2
Inoue, S.3
Shao, W.L.4
Miller, W.H.5
Evans, R.M.6
-
14
-
-
17144458786
-
Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia
-
Grignani F., de Matteis S., Nervi C., et al. Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia. Nature. 391:1998;815-818
-
(1998)
Nature
, vol.391
, pp. 815-818
-
-
Grignani, F.1
De Matteis, S.2
Nervi, C.3
-
15
-
-
0029942879
-
Accelerated degradation of PML-retinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia. Possible role of the proteasome pathway
-
Yoshida H., Kitamura K., Tanaka K., et al. Accelerated degradation of PML-retinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia. Possible role of the proteasome pathway. Cancer Res. 56:1996;2945-2948
-
(1996)
Cancer Res.
, vol.56
, pp. 2945-2948
-
-
Yoshida, H.1
Kitamura, K.2
Tanaka, K.3
-
16
-
-
0029919406
-
The PML/RAR alpha oncoprotein is a direct molecular target of retinoic acid in acute promyelocytic leukemia cells
-
Raelson J.V., Nervi C., Rosenauer A., et al. The PML/RAR alpha oncoprotein is a direct molecular target of retinoic acid in acute promyelocytic leukemia cells. Blood. 88:1996;2826-2832
-
(1996)
Blood
, vol.88
, pp. 2826-2832
-
-
Raelson, J.V.1
Nervi, C.2
Rosenauer, A.3
-
17
-
-
0033592948
-
Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RAR alpha) and oncogenic RAR alpha fusion proteins
-
Zhu J., Gianni M., Kopf E., et al. Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RAR alpha) and oncogenic RAR alpha fusion proteins. Proc. Natl. Acad. Sci. USA. 96:1999;14807-14812
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14807-14812
-
-
Zhu, J.1
Gianni, M.2
Kopf, E.3
-
18
-
-
0028095410
-
PML, a growth suppressor disrupted in acute promyelocytic leukemia
-
Mu Z.M., Chin K.V., Liu J.H., Lozano G., Chang K.S. PML, a growth suppressor disrupted in acute promyelocytic leukemia. Mol. Cell. Biol. 14:1994;6858-6867
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6858-6867
-
-
Mu, Z.M.1
Chin, K.V.2
Liu, J.H.3
Lozano, G.4
Chang, K.S.5
-
19
-
-
0031794632
-
PML induces a caspase-independent cell death process
-
Quignon F., de Bels F., Koken M., Feunteun J., Ameisen J.-C., de Thé H. PML induces a caspase-independent cell death process. Nat Genet. 20:1998;259-265
-
(1998)
Nat Genet
, vol.20
, pp. 259-265
-
-
Quignon, F.1
De Bels, F.2
Koken, M.3
Feunteun, J.4
Ameisen, J.-C.5
De Thé, H.6
-
20
-
-
0028916423
-
The PML growth-suppressor has an altered expression in human oncogenesis
-
Koken M.H.M., Linares-Cruz G., Quignon F., et al. The PML growth-suppressor has an altered expression in human oncogenesis. Oncogene. 10:1995;1315-1324
-
(1995)
Oncogene
, vol.10
, pp. 1315-1324
-
-
Koken, M.H.M.1
Linares-Cruz, G.2
Quignon, F.3
-
21
-
-
0028951531
-
PML nuclear bodies are general targets for inflammation and cell proliferation
-
Terris B., Baldin V., Dubois S., et al. PML nuclear bodies are general targets for inflammation and cell proliferation. Cancer Res. 55:1995;1590-1597
-
(1995)
Cancer Res.
, vol.55
, pp. 1590-1597
-
-
Terris, B.1
Baldin, V.2
Dubois, S.3
-
22
-
-
0031791875
-
PML is essential for multiple apoptotic pathways
-
Wang Z.-G., Ruggero D., Ronchetti S., et al. PML is essential for multiple apoptotic pathways. Nat Genet. 20:1998;266-272
-
(1998)
Nat Genet
, vol.20
, pp. 266-272
-
-
Wang, Z.-G.1
Ruggero, D.2
Ronchetti, S.3
-
23
-
-
0000237552
-
Role of PML in cell growth and the retinoic acid pathway
-
Wang Z.G., Delva L., Gaboli M., et al. Role of PML in cell growth and the retinoic acid pathway. Science. 279:1998;1547-1551
-
(1998)
Science
, vol.279
, pp. 1547-1551
-
-
Wang, Z.G.1
Delva, L.2
Gaboli, M.3
-
24
-
-
0028293945
-
The t(15;17) translocation alters a nuclear body in a RA-reversible fashion
-
Koken M.H.M., Puvion-Dutilleul F., Guillemin M.C., et al. The t(15;17) translocation alters a nuclear body in a RA-reversible fashion. EMBO J. 13:1994;1073-1083
-
(1994)
EMBO J.
, vol.13
, pp. 1073-1083
-
-
Koken, M.H.M.1
Puvion-Dutilleul, F.2
Guillemin, M.C.3
-
25
-
-
0028158682
-
Retinoic acid regulates aberrant nuclear localization of PML/RARα in acute promyelocytic leukemia cells
-
Weis K., Rambaud S., Lavau C., et al. Retinoic acid regulates aberrant nuclear localization of PML/RARα in acute promyelocytic leukemia cells. Cell. 76:1994;345-356
-
(1994)
Cell
, vol.76
, pp. 345-356
-
-
Weis, K.1
Rambaud, S.2
Lavau, C.3
-
26
-
-
0028179010
-
A novel macromolecular structure is a target of the promyelocyte- retinoic acid receptor oncoprotein
-
Dyck J.A., Maul G.G., Miller W.H., Chen J.D., Kakizuka A., Evans R.M. A novel macromolecular structure is a target of the promyelocyte- retinoic acid receptor oncoprotein. Cell. 76:1994;333-343
-
(1994)
Cell
, vol.76
, pp. 333-343
-
-
Dyck, J.A.1
Maul, G.G.2
Miller, W.H.3
Chen, J.D.4
Kakizuka, A.5
Evans, R.M.6
-
27
-
-
0026532516
-
A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies
-
Stuurman N., de Graaf A., Floore A., et al. A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies. J. Cell Sci. 101:1992;773-784
-
(1992)
J. Cell Sci.
, vol.101
, pp. 773-784
-
-
Stuurman, N.1
De Graaf, A.2
Floore, A.3
-
28
-
-
0032721540
-
PML is critical for N.D.10 formation and recruits the PML-interacting protein Daxx to this nuclear structure when modified by SUMO-1
-
Ishov A.M., Sotnikov A.G., Negorev D., et al. PML is critical for N.D.10 formation and recruits the PML-interacting protein Daxx to this nuclear structure when modified by SUMO-1. J. Cell Biol. 147:1999;221-234
-
(1999)
J. Cell Biol.
, vol.147
, pp. 221-234
-
-
Ishov, A.M.1
Sotnikov, A.G.2
Negorev, D.3
-
29
-
-
0035908032
-
Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As(2)O(3)-induced PML or PML/retinoic acid receptor alpha degradation
-
Lallemand-Breitenbach V., Zhu J., Puvion F., et al. Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As(2)O(3)-induced PML or PML/retinoic acid receptor alpha degradation. J Exp Med. 193:2001;1361-1372
-
(2001)
J Exp Med.
, vol.193
, pp. 1361-1372
-
-
Lallemand-Breitenbach, V.1
Zhu, J.2
Puvion, F.3
-
30
-
-
0343776952
-
Role of SUMO-1-modified PML in nuclear body formation
-
Zhong S., Muller S., Ronchetti S., Freemont P.S., Dejean A., Pandolfi P.P. Role of SUMO-1-modified PML in nuclear body formation. Blood. 95:2000;2748-2752
-
(2000)
Blood
, vol.95
, pp. 2748-2752
-
-
Zhong, S.1
Muller, S.2
Ronchetti, S.3
Freemont, P.S.4
Dejean, A.5
Pandolfi, P.P.6
-
31
-
-
0010740572
-
4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins
-
4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins. Blood. 88:1996;1052-1061
-
(1996)
Blood
, vol.88
, pp. 1052-1061
-
-
Chen, G.-Q.1
Zhu, J.2
Shi, X.-G.3
-
32
-
-
0030610686
-
3 exerts dose- dependent dual effects on APL cells
-
3 exerts dose- dependent dual effects on APL cells Blood. 89:1997;3345-3353
-
(1997)
Blood
, vol.89
, pp. 3345-3353
-
-
Chen, G.-Q.1
Shi, X.-G.2
Tang, W.3
-
33
-
-
9344234374
-
Pharmacokinetics and efficacy of low-dose all-trans retinoic acid in the treatment of acute promyelocytic leukemia
-
Chen G.Q., Shen Z.X., Wu F., et al. Pharmacokinetics and efficacy of low-dose all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Leukemia. 10:1996;825-828
-
(1996)
Leukemia
, vol.10
, pp. 825-828
-
-
Chen, G.Q.1
Shen, Z.X.2
Wu, F.3
-
34
-
-
0033526012
-
Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia
-
Lallemand-Breitenbach V., Guillemin M.-C., Janin A., et al. Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia. J. Exp. Med. 189:1999;1043-1052
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1043-1052
-
-
Lallemand-Breitenbach, V.1
Guillemin, M.-C.2
Janin, A.3
-
35
-
-
0030890942
-
Arsenic-induced PML targeting onto nuclear bodies: Implications for the treatment of acute promyelocytic leukemia
-
Zhu J., Koken M.H.M., Quignon F., et al. Arsenic-induced PML targeting onto nuclear bodies. implications for the treatment of acute promyelocytic leukemia Proc. Natl. Acad. Sci. USA. 94:1997;3978-3983
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3978-3983
-
-
Zhu, J.1
Koken, M.H.M.2
Quignon, F.3
-
36
-
-
0012316186
-
Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1
-
vom Baur E., Zechel C., Heery D., et al. Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. EMBO J. 15:1996;110-124
-
(1996)
EMBO J.
, vol.15
, pp. 110-124
-
-
Vom Baur, E.1
Zechel, C.2
Heery, D.3
-
37
-
-
17944372810
-
Novel differentiation-inducing therapy for acute promyelocytic leukemia with a combination of arsenic trioxide and GM-CSF
-
Muto A., Kizaki M., Kawamura C., et al A. novel differentiation-inducing therapy for acute promyelocytic leukemia with a combination of arsenic trioxide and GM-CSF. Leukemia. 15:2001;1176-1184
-
(2001)
Leukemia
, vol.15
, pp. 1176-1184
-
-
Muto, A.1
Kizaki, M.2
Kawamura, C.3
Et Al, A.4
-
38
-
-
0036464602
-
Synergic effects of arsenic trioxide and cAMP during acute promyelocytic leukemia cell maturation subtends a novel signaling cross-talk
-
Zhu Q., Zhang J.W., Zhu H.Q., et al. Synergic effects of arsenic trioxide and cAMP during acute promyelocytic leukemia cell maturation subtends a novel signaling cross-talk. Blood. 99:2002;1014-1022
-
(2002)
Blood
, vol.99
, pp. 1014-1022
-
-
Zhu, Q.1
Zhang, J.W.2
Zhu, H.Q.3
-
39
-
-
0034961181
-
Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL
-
Altucci L., Rossin A., Raffelsberger W., Reitmair A., Chomienne C., Gronemeyer H. Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL. Nat Med. 7:2001;680-686
-
(2001)
Nat Med.
, vol.7
, pp. 680-686
-
-
Altucci, L.1
Rossin, A.2
Raffelsberger, W.3
Reitmair, A.4
Chomienne, C.5
Gronemeyer, H.6
-
40
-
-
0034730198
-
Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins
-
Rego E.M., He L.Z., Warrell R.P. Jr., Wang Z.G., Pandolfi P.P. Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins. Proc Natl Acad Sci USA. 97:2000;10173-10178
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10173-10178
-
-
Rego, E.M.1
He, L.Z.2
Warrell Jr., R.P.3
Wang, Z.G.4
Pandolfi, P.P.5
-
41
-
-
0035161286
-
Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo
-
Jing Y., Wang L., Xia L., et al. Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo. Blood. 97:2001;264-269
-
(2001)
Blood
, vol.97
, pp. 264-269
-
-
Jing, Y.1
Wang, L.2
Xia, L.3
-
42
-
-
0034786069
-
Arsenic trioxide is a potent inhibitor of the interaction of SMRT corepressor with Its transcription factor partners, including the PML-retinoic acid receptor alpha oncoprotein found in human acute promyelocytic leukemia
-
Hong S.H., Yang Z., Privalsky M.L. Arsenic trioxide is a potent inhibitor of the interaction of SMRT corepressor with Its transcription factor partners, including the PML-retinoic acid receptor alpha oncoprotein found in human acute promyelocytic leukemia. Mol Cell Biol. 21:2001;7172-7182
-
(2001)
Mol Cell Biol.
, vol.21
, pp. 7172-7182
-
-
Hong, S.H.1
Yang, Z.2
Privalsky, M.L.3
-
43
-
-
0035045676
-
Modeling acute promyelocytic leukemia in the mouse: New insights in the pathogenesis of human leukemias
-
Merghoub T., Gurrieri C., Piazza F., Pandolfi P.P. Modeling acute promyelocytic leukemia in the mouse. new insights in the pathogenesis of human leukemias Blood Cells Mol Dis. 27:2001;231-248
-
(2001)
Blood Cells Mol Dis
, vol.27
, pp. 231-248
-
-
Merghoub, T.1
Gurrieri, C.2
Piazza, F.3
Pandolfi, P.P.4
-
44
-
-
0034144710
-
Leukemia initiated by PMLRARalpha: The PML domain plays a critical role while retinoic acid-mediated transactivation is dispensable
-
Kogan S.C., Hong S.H., Shultz D.B., Privalsky M.L., Bishop J.M. Leukemia initiated by PMLRARalpha. the PML domain plays a critical role while retinoic acid-mediated transactivation is dispensable Blood. 95:2000;1541-1550
-
(2000)
Blood
, vol.95
, pp. 1541-1550
-
-
Kogan, S.C.1
Hong, S.H.2
Shultz, D.B.3
Privalsky, M.L.4
Bishop, J.M.5
-
45
-
-
0035189761
-
Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia
-
He L.Z., Tolentino T., Grayson P., et al. Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia. J Clin Invest. 108:2001;1321-1330
-
(2001)
J Clin Invest.
, vol.108
, pp. 1321-1330
-
-
He, L.Z.1
Tolentino, T.2
Grayson, P.3
|